Page last updated: 2024-11-05

zonisamide and Intellectual Disability

zonisamide has been researched along with Intellectual Disability in 3 studies

Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.

Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)

Research Excerpts

ExcerptRelevanceReference
"This study aimed to evaluate the tolerability and efficacy of zonisamide (ZNS) in adult patients with drug-resistant epilepsy and intellectual disability (ID) at our epilepsy centre."8.02Long-term effects of zonisamide in adult patients with intellectual disability. ( Eck, K; Hamer, H; Kerling, F; Rauch, C; Winterholler, M, 2021)
"Zonisamide is a new drug with broad-spectrum antiepileptic activity against partial as well as generalized seizures."6.69Long-term effects of zonisamide in the treatment of epilepsy in children with intellectual disability. ( Cho, K; Iinuma, K; Kajii, N; Minami, T; Tachi, N, 1998)
"This study aimed to evaluate the tolerability and efficacy of zonisamide (ZNS) in adult patients with drug-resistant epilepsy and intellectual disability (ID) at our epilepsy centre."4.02Long-term effects of zonisamide in adult patients with intellectual disability. ( Eck, K; Hamer, H; Kerling, F; Rauch, C; Winterholler, M, 2021)
"Zonisamide is a new drug with broad-spectrum antiepileptic activity against partial as well as generalized seizures."2.69Long-term effects of zonisamide in the treatment of epilepsy in children with intellectual disability. ( Cho, K; Iinuma, K; Kajii, N; Minami, T; Tachi, N, 1998)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Eck, K1
Rauch, C1
Kerling, F1
Hamer, H1
Winterholler, M1
Ortiz-Madinaveitia, S1
Serrano-Madrid, ML1
Conejo-Moreno, D1
Sagarra-Mur, D1
Jimenez-Corral, C1
Gutierrez-Alvarez, AM1
Iinuma, K1
Minami, T1
Cho, K1
Kajii, N1
Tachi, N1

Trials

1 trial available for zonisamide and Intellectual Disability

ArticleYear
Long-term effects of zonisamide in the treatment of epilepsy in children with intellectual disability.
    Journal of intellectual disability research : JIDR, 1998, Volume: 42 Suppl 1

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Intellectual

1998

Other Studies

2 other studies available for zonisamide and Intellectual Disability

ArticleYear
Long-term effects of zonisamide in adult patients with intellectual disability.
    Acta neurologica Scandinavica, 2021, Volume: 144, Issue:3

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Female; Humans; Intellectual Disability; Middle Aged; Retr

2021
[Early onset epileptic encephalopathy in a patient with mutation in
    Revista de neurologia, 2017, Dec-16, Volume: 65, Issue:12

    Topics: Age of Onset; Amino Acid Substitution; Anticonvulsants; Child, Preschool; Drug Resistant Epilepsy; D

2017