zonisamide has been researched along with Innate Inflammatory Response in 5 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present findings revealed that zonisamide treatment prevented the development of seizures in animals." | 7.88 | A mechanistic approach to explore the neuroprotective potential of zonisamide in seizures. ( Attri, SV; Kumar, B; Medhi, B; Modi, M; Patial, A; Saikia, B, 2018) |
| "We evaluated the effects of zonisamide on inflammatory and neuropathic pain using the mouse formalin test and streptozotocin (STZ)-induced diabetic mice with a reduced withdrawal threshold to mechanical stimuli, respectively." | 7.74 | Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy. ( Murakami, T; Ono, H; Tanabe, M, 2008) |
| "Degenerative cervical myelopathy (DCM) is a severe condition of the spinal cord caused by chronic compression." | 5.91 | Zonisamide improves Fas/FasL-mediated apoptosis and inflammation in a degenerative cervical myelopathy rat model. ( Tan, Y; Wang, Z; Xu, F, 2023) |
| "The present findings revealed that zonisamide treatment prevented the development of seizures in animals." | 3.88 | A mechanistic approach to explore the neuroprotective potential of zonisamide in seizures. ( Attri, SV; Kumar, B; Medhi, B; Modi, M; Patial, A; Saikia, B, 2018) |
| "We evaluated the effects of zonisamide on inflammatory and neuropathic pain using the mouse formalin test and streptozotocin (STZ)-induced diabetic mice with a reduced withdrawal threshold to mechanical stimuli, respectively." | 3.74 | Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy. ( Murakami, T; Ono, H; Tanabe, M, 2008) |
| "Degenerative cervical myelopathy (DCM) is a severe condition of the spinal cord caused by chronic compression." | 1.91 | Zonisamide improves Fas/FasL-mediated apoptosis and inflammation in a degenerative cervical myelopathy rat model. ( Tan, Y; Wang, Z; Xu, F, 2023) |
| " The most widely used MAO-B inhibitor to maintain the bioavailability of dopamine in the brain of PD patients is L-deprenyl, despite of its potential side-effects." | 1.48 | Garcinol, an effective monoamine oxidase-B inhibitor for the treatment of Parkinson's disease. ( Bhattacharya, P; Borah, A; Chakrabarty, J; Dutta, A; Mazumder, MK; Paul, R; Phukan, BC, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Wang, Z | 1 |
| Tan, Y | 1 |
| Xu, F | 1 |
| Kumar, B | 1 |
| Medhi, B | 1 |
| Modi, M | 1 |
| Saikia, B | 1 |
| Attri, SV | 1 |
| Patial, A | 1 |
| Mazumder, MK | 1 |
| Paul, R | 1 |
| Phukan, BC | 1 |
| Dutta, A | 1 |
| Chakrabarty, J | 1 |
| Bhattacharya, P | 1 |
| Borah, A | 1 |
| Tanabe, M | 1 |
| Murakami, T | 1 |
| Ono, H | 1 |
5 other studies available for zonisamide and Innate Inflammatory Response
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Zonisamide improves Fas/FasL-mediated apoptosis and inflammation in a degenerative cervical myelopathy rat model.
Topics: Animals; Apoptosis; Caspase 10; Caspase 3; Caspase 8; Caspase 9; Fas Ligand Protein; Inflammation; P | 2023 |
A mechanistic approach to explore the neuroprotective potential of zonisamide in seizures.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroshock; Epilepsy; Free Radicals; Inflammatio | 2018 |
Garcinol, an effective monoamine oxidase-B inhibitor for the treatment of Parkinson's disease.
Topics: Humans; Inflammation; Isoxazoles; Levodopa; Ligands; Molecular Conformation; Molecular Docking Simul | 2018 |
Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Formaldehyde; Inflammation; Isoxazo | 2008 |