Page last updated: 2024-11-05

zonisamide and Headache

zonisamide has been researched along with Headache in 5 studies

Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.

Headache: The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"At this moment, zonisamide represents a robust option in the treatment of a large number of patients with epilepsy, based on its multiple mechanism of action and efficacy in different situations."8.89[Zonisamide in the epilepsy treatment: a literature review from add-on therapy to monotherapy]. ( Serrano-Castro, PJ; Villanueva, V, 2013)
"Generally, prognosis of hypertensive encephalopathy in childhood is favorable."5.33Zonisamide eradicated paroxysmal headache with EEG abnormalities triggered by hypertensive encephalopathy due to purpura nephritic syndrome. ( Anzai, Y; Hayashi, M; Ohya, T, 2006)
"At this moment, zonisamide represents a robust option in the treatment of a large number of patients with epilepsy, based on its multiple mechanism of action and efficacy in different situations."4.89[Zonisamide in the epilepsy treatment: a literature review from add-on therapy to monotherapy]. ( Serrano-Castro, PJ; Villanueva, V, 2013)
"One hundred and twenty migraineurs who were refractory to topiramate were recruited."2.79Efficacy of zonisamide in migraineurs with nonresponse to topiramate. ( Chung, JY; Kim, M; Kim, MW, 2014)
" The most common adverse events were somnolence, headache, dizziness, and nausea during the titration phase and headache and pharyngitis during the fixed-dose assessment phase."2.71Dose-dependent safety and efficacy of zonisamide: a randomized, double-blind, placebo-controlled study in patients with refractory partial seizures. ( Bitenskyy, V; Brodie, MJ; Duncan, R; Lucas, C; Solyom, A; Vespignani, H, 2005)
"Generally, prognosis of hypertensive encephalopathy in childhood is favorable."1.33Zonisamide eradicated paroxysmal headache with EEG abnormalities triggered by hypertensive encephalopathy due to purpura nephritic syndrome. ( Anzai, Y; Hayashi, M; Ohya, T, 2006)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Villanueva, V1
Serrano-Castro, PJ1
Chung, JY1
Kim, MW1
Kim, M1
Frediani, F1
Brodie, MJ1
Duncan, R1
Vespignani, H1
Solyom, A1
Bitenskyy, V1
Lucas, C1
Anzai, Y1
Hayashi, M1
Ohya, T1

Reviews

2 reviews available for zonisamide and Headache

ArticleYear
[Zonisamide in the epilepsy treatment: a literature review from add-on therapy to monotherapy].
    Revista de neurologia, 2013, Apr-16, Volume: 56, Issue:8

    Topics: Adult; Animals; Anorexia; Anticonvulsants; Antioxidants; Carbonic Anhydrase Inhibitors; Child; Dizzi

2013
Anticonvulsant drugs in primary headaches prophylaxis.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2004, Volume: 25 Suppl 3

    Topics: Amines; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fruct

2004

Trials

2 trials available for zonisamide and Headache

ArticleYear
Efficacy of zonisamide in migraineurs with nonresponse to topiramate.
    BioMed research international, 2014, Volume: 2014

    Topics: Adult; Female; Fructose; Headache; Humans; Isoxazoles; Male; Middle Aged; Migraine Disorders; Parest

2014
Dose-dependent safety and efficacy of zonisamide: a randomized, double-blind, placebo-controlled study in patients with refractory partial seizures.
    Epilepsia, 2005, Volume: 46, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Child; Dose-Response Relationship, Drug; Doub

2005

Other Studies

1 other study available for zonisamide and Headache

ArticleYear
Zonisamide eradicated paroxysmal headache with EEG abnormalities triggered by hypertensive encephalopathy due to purpura nephritic syndrome.
    Brain & development, 2006, Volume: 28, Issue:9

    Topics: Anticonvulsants; Child, Preschool; Electroencephalography; Female; Headache; Humans; Hypertensive En

2006