zonisamide has been researched along with Exanthema in 4 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
Exanthema: Diseases in which skin eruptions or rashes are a prominent manifestation. Classically, six such diseases were described with similar rashes; they were numbered in the order in which they were reported. Only the fourth (Duke's disease), fifth (ERYTHEMA INFECTIOSUM), and sixth (EXANTHEMA SUBITUM) numeric designations survive as occasional synonyms in current terminology.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Drug rash with eosinophilia and systemic symptoms (DRESS syndrome) is a very serious but rare adverse effect of anticonvulsants such as carbamazepine and phenytoin; however, the reported incidence on zonisamide is scant." | 8.12 | Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in a paediatric patient taking zonisamide. ( Govindan, R; Sharma, S; Trivedi, A, 2022) |
| " The current report describes a man who was prescribed zonisamide for epilepsy and subsequently developed widespread skin rash, acute kidney injury, high-grade fever, eosinophilia, liver dysfunction, lymphadenopathy and an increase in antihuman herpesvirus-6 immunoglobulin G titer." | 7.76 | Acute kidney injury caused by zonisamide-induced hypersensitivity syndrome. ( Fujita, Y; Hasegawa, M; Matsunaga, K; Murakami, K; Nabeshima, K; Nakai, S; Tomita, M; Yamakita, T, 2010) |
| " Drug rash with eosinophilia and systemic symptoms (DRESS syndrome) is a very serious but rare adverse effect of anticonvulsants such as carbamazepine and phenytoin; however, the reported incidence on zonisamide is scant." | 4.12 | Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in a paediatric patient taking zonisamide. ( Govindan, R; Sharma, S; Trivedi, A, 2022) |
| " The current report describes a man who was prescribed zonisamide for epilepsy and subsequently developed widespread skin rash, acute kidney injury, high-grade fever, eosinophilia, liver dysfunction, lymphadenopathy and an increase in antihuman herpesvirus-6 immunoglobulin G titer." | 3.76 | Acute kidney injury caused by zonisamide-induced hypersensitivity syndrome. ( Fujita, Y; Hasegawa, M; Matsunaga, K; Murakami, K; Nabeshima, K; Nakai, S; Tomita, M; Yamakita, T, 2010) |
| "Zonisamide (ZNS) is an anticonvulsant (AC) that contains a sulpha moiety potentially triggering hypersensitivity syndrome reactions (HSR)." | 1.35 | Predicting possible zonisamide hypersensitivity syndrome. ( Cohen, L; Kessas, M; Lee, AW; Malkiewicz, IM; Neuman, MG; Shear, NH, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Trivedi, A | 1 |
| Sharma, S | 1 |
| Govindan, R | 1 |
| Hosohata, K | 1 |
| Inada, A | 1 |
| Oyama, S | 1 |
| Niinomi, I | 1 |
| Wakabayashi, T | 1 |
| Iwanaga, K | 1 |
| Neuman, MG | 1 |
| Shear, NH | 1 |
| Malkiewicz, IM | 1 |
| Kessas, M | 1 |
| Lee, AW | 1 |
| Cohen, L | 1 |
| Fujita, Y | 1 |
| Hasegawa, M | 1 |
| Nabeshima, K | 1 |
| Tomita, M | 1 |
| Murakami, K | 1 |
| Nakai, S | 1 |
| Yamakita, T | 1 |
| Matsunaga, K | 1 |
4 other studies available for zonisamide and Exanthema
| Article | Year |
|---|---|
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in a paediatric patient taking zonisamide.
Topics: Child; Drug Hypersensitivity Syndrome; Eosinophilia; Exanthema; Humans; Male; Phenytoin; Zonisamide | 2022 |
Adverse Cutaneous Drug Reactions Associated with Old- and New- Generation Antiepileptic Drugs Using the Japanese Pharmacovigilance Database.
Topics: Anticonvulsants; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Exanthema; Fem | 2019 |
Predicting possible zonisamide hypersensitivity syndrome.
Topics: Adult; Age Factors; Aged; Animals; Anticonvulsants; Cell Survival; Diagnostic Techniques and Procedu | 2008 |
Acute kidney injury caused by zonisamide-induced hypersensitivity syndrome.
Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Adult; Anticonvulsants; Drug Hypersensitivity; Epileps | 2010 |