zonisamide has been researched along with Exanthem in 4 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Drug rash with eosinophilia and systemic symptoms (DRESS syndrome) is a very serious but rare adverse effect of anticonvulsants such as carbamazepine and phenytoin; however, the reported incidence on zonisamide is scant." | 8.12 | Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in a paediatric patient taking zonisamide. ( Govindan, R; Sharma, S; Trivedi, A, 2022) |
| " The current report describes a man who was prescribed zonisamide for epilepsy and subsequently developed widespread skin rash, acute kidney injury, high-grade fever, eosinophilia, liver dysfunction, lymphadenopathy and an increase in antihuman herpesvirus-6 immunoglobulin G titer." | 7.76 | Acute kidney injury caused by zonisamide-induced hypersensitivity syndrome. ( Fujita, Y; Hasegawa, M; Matsunaga, K; Murakami, K; Nabeshima, K; Nakai, S; Tomita, M; Yamakita, T, 2010) |
| " Drug rash with eosinophilia and systemic symptoms (DRESS syndrome) is a very serious but rare adverse effect of anticonvulsants such as carbamazepine and phenytoin; however, the reported incidence on zonisamide is scant." | 4.12 | Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in a paediatric patient taking zonisamide. ( Govindan, R; Sharma, S; Trivedi, A, 2022) |
| " The current report describes a man who was prescribed zonisamide for epilepsy and subsequently developed widespread skin rash, acute kidney injury, high-grade fever, eosinophilia, liver dysfunction, lymphadenopathy and an increase in antihuman herpesvirus-6 immunoglobulin G titer." | 3.76 | Acute kidney injury caused by zonisamide-induced hypersensitivity syndrome. ( Fujita, Y; Hasegawa, M; Matsunaga, K; Murakami, K; Nabeshima, K; Nakai, S; Tomita, M; Yamakita, T, 2010) |
| "Zonisamide (ZNS) is an anticonvulsant (AC) that contains a sulpha moiety potentially triggering hypersensitivity syndrome reactions (HSR)." | 1.35 | Predicting possible zonisamide hypersensitivity syndrome. ( Cohen, L; Kessas, M; Lee, AW; Malkiewicz, IM; Neuman, MG; Shear, NH, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Trivedi, A | 1 |
| Sharma, S | 1 |
| Govindan, R | 1 |
| Hosohata, K | 1 |
| Inada, A | 1 |
| Oyama, S | 1 |
| Niinomi, I | 1 |
| Wakabayashi, T | 1 |
| Iwanaga, K | 1 |
| Neuman, MG | 1 |
| Shear, NH | 1 |
| Malkiewicz, IM | 1 |
| Kessas, M | 1 |
| Lee, AW | 1 |
| Cohen, L | 1 |
| Fujita, Y | 1 |
| Hasegawa, M | 1 |
| Nabeshima, K | 1 |
| Tomita, M | 1 |
| Murakami, K | 1 |
| Nakai, S | 1 |
| Yamakita, T | 1 |
| Matsunaga, K | 1 |
4 other studies available for zonisamide and Exanthem
| Article | Year |
|---|---|
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in a paediatric patient taking zonisamide.
Topics: Child; Drug Hypersensitivity Syndrome; Eosinophilia; Exanthema; Humans; Male; Phenytoin; Zonisamide | 2022 |
Adverse Cutaneous Drug Reactions Associated with Old- and New- Generation Antiepileptic Drugs Using the Japanese Pharmacovigilance Database.
Topics: Anticonvulsants; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Exanthema; Fem | 2019 |
Predicting possible zonisamide hypersensitivity syndrome.
Topics: Adult; Age Factors; Aged; Animals; Anticonvulsants; Cell Survival; Diagnostic Techniques and Procedu | 2008 |
Acute kidney injury caused by zonisamide-induced hypersensitivity syndrome.
Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Adult; Anticonvulsants; Drug Hypersensitivity; Epileps | 2010 |