zonisamide has been researched along with Epilepsies, Myoclonic in 10 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
Epilepsies, Myoclonic: A clinically diverse group of epilepsy syndromes characterized either by myoclonic seizures or by myoclonus in association with other seizure types. Myoclonic epilepsy syndromes are divided into three subtypes based on etiology: familial, cryptogenic, and symptomatic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the efficacy and safety of zonisamide (ZNS) adjunctive therapy in children with intractable epilepsy to existing antiepileptic drugs (AEDs)." | 9.14 | Efficacy and tolerability of adjunctive therapy with zonisamide in childhood intractable epilepsy. ( Kang, HC; Kim, HD; Lee, JS; Lee, YJ; Seo, JH, 2010) |
| "This study investigated the efficacy and safety of zonisamide (ZNS) adjunctive therapy in children with intractable epilepsy to existing antiepileptic drugs (AEDs)." | 5.14 | Efficacy and tolerability of adjunctive therapy with zonisamide in childhood intractable epilepsy. ( Kang, HC; Kim, HD; Lee, JS; Lee, YJ; Seo, JH, 2010) |
| "Zonisamide (ZNS) is a broad-spectrum antiepileptic drug in both animal models of epilepsy and patients with epilepsy." | 4.80 | Zonisamide. ( Leppik, IE, 1999) |
| "Vigabatrin has shown promise in treating IS patients, particularly those with tuberous sclerosis." | 2.42 | Pharmacologic treatment of the catastrophic epilepsies. ( Conry, JA, 2004) |
| "Severe myoclonic epilepsy of infants usually worsens with lamotrigine, but occasionally, children improve." | 2.40 | Myoclonus and epilepsy in childhood: a review of treatment with valproate, ethosuximide, lamotrigine and zonisamide. ( Wallace, SJ, 1998) |
| "The recommended treatment for juvenile myoclonic epilepsy (JME) is valproate (VPA)." | 1.32 | Efficacy and tolerability of zonisamide in juvenile myoclonic epilepsy. ( Hardison, H; Khurana, DS; Kothare, SV; Legido, A; Melvin, JJ; Valencia, I, 2004) |
| "Zonisamide was given at doses of 100-600 mg/day for a period of 2 to 3 years." | 1.30 | Zonisamide for progressive myoclonus epilepsy: long-term observations in seven patients. ( Ben-Menachem, E; Kyllerman, M, 1998) |
| "Two patients with progressive myoclonus epilepsy of the Unverricht-Lundborg type and with intractable seizures in spite of standard anticonvulsant regimens were treated with zonisamide." | 1.27 | Progressive myoclonus epilepsy treated with zonisamide. ( Gumnit, RJ; Henry, TR; Jacobs, M; Leppik, IE, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, YJ | 1 |
| Kang, HC | 1 |
| Seo, JH | 1 |
| Lee, JS | 1 |
| Kim, HD | 1 |
| Kelemen, A | 1 |
| Rásonyl, G | 1 |
| Neuwirth, M | 1 |
| Barcs, G | 1 |
| Szucs, A | 1 |
| Jakus, R | 1 |
| Fabó, D | 1 |
| Juhos, V | 1 |
| Pálfy, B | 1 |
| Halász, P | 1 |
| Conry, JA | 1 |
| Kothare, SV | 1 |
| Valencia, I | 1 |
| Khurana, DS | 1 |
| Hardison, H | 1 |
| Melvin, JJ | 1 |
| Legido, A | 1 |
| Kyllerman, M | 1 |
| Ben-Menachem, E | 1 |
| Wallace, SJ | 1 |
| Leppik, IE | 2 |
| Kanazawa, O | 1 |
| Sander, JW | 1 |
| Hart, YM | 1 |
| Duncan, JS | 1 |
| Shorvon, SD | 1 |
| Henry, TR | 1 |
| Gumnit, RJ | 1 |
| Jacobs, M | 1 |
4 reviews available for zonisamide and Epilepsies, Myoclonic
| Article | Year |
|---|---|
Pharmacologic treatment of the catastrophic epilepsies.
Topics: Anticonvulsants; Child, Preschool; Epilepsies, Myoclonic; Epilepsy; Fructose; Humans; Infant; Isoxaz | 2004 |
Myoclonus and epilepsy in childhood: a review of treatment with valproate, ethosuximide, lamotrigine and zonisamide.
Topics: Anticonvulsants; Child; Child, Preschool; Epilepsies, Myoclonic; Ethosuximide; Humans; Infant; Isoxa | 1998 |
Zonisamide.
Topics: Adult; Animals; Anticonvulsants; Clinical Trials as Topic; Disease Models, Animal; Drug Administrati | 1999 |
Refractory grand mal seizures with onset during infancy including severe myoclonic epilepsy in infancy.
Topics: Anticonvulsants; Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic; Humans; Infant; Isoxazoles; Zonisami | 2001 |
1 trial available for zonisamide and Epilepsies, Myoclonic
| Article | Year |
|---|---|
Efficacy and tolerability of adjunctive therapy with zonisamide in childhood intractable epilepsy.
Topics: Adolescent; Anticonvulsants; Chemotherapy, Adjuvant; Child; Child, Preschool; Dose-Response Relation | 2010 |
5 other studies available for zonisamide and Epilepsies, Myoclonic
| Article | Year |
|---|---|
Our clinical experience with zonisamide in resistant generalized epilepsy syndromes.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Confusion; Disorders of Excessive Somno | 2011 |
Efficacy and tolerability of zonisamide in juvenile myoclonic epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Child; Dose-Response Relationship, Drug; Drug Interactions; Drug | 2004 |
Zonisamide for progressive myoclonus epilepsy: long-term observations in seven patients.
Topics: Adult; Anticonvulsants; Epilepsies, Myoclonic; Female; Humans; Isoxazoles; Male; Middle Aged; Time F | 1998 |
Zonisamide usage.
Topics: Epilepsies, Myoclonic; Humans; Isoxazoles; Kidney Calculi; Oxazoles; Zonisamide | 1989 |
Progressive myoclonus epilepsy treated with zonisamide.
Topics: Adult; Epilepsies, Myoclonic; Humans; Isoxazoles; Male; Oxazoles; Zonisamide | 1988 |