Page last updated: 2024-11-05

zonisamide and Drug Refractory Epilepsy

zonisamide has been researched along with Drug Refractory Epilepsy in 8 studies

Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.

Research Excerpts

ExcerptRelevanceReference
"We present a summary of clinical cases of oral zonisamide (ZNS) used to treat refractory and super-refractory episodes of status epilepticus (SE)."9.05Treatment of status epilepticus with zonisamide: A multicenter cohort study of 34 patients and review of literature. ( Bauer, S; Hubert, K; Knake, S; Rosenow, F; Strzelczyk, A; Voss, M, 2020)
"Zonisamide (ZNS) is a new generation antiepileptic drug (AED) used in refractory epilepsy."8.12Effectiveness of zonisamide in childhood refractory epilepsy. ( Aslan, M; Gungor, S, 2022)
"Pregnancy is a state where drug pharmacokinetic changes are more pronounced and more rapid than any other period of life."5.48Effect of zonisamide on refractory epilepsy during pregnancy in lamotrigine resistant kindled rats. ( Keramati, K; Mahdavi, A; Moezifar, M; Narenji Sani, R; Saberi, N, 2018)
"We present a summary of clinical cases of oral zonisamide (ZNS) used to treat refractory and super-refractory episodes of status epilepticus (SE)."5.05Treatment of status epilepticus with zonisamide: A multicenter cohort study of 34 patients and review of literature. ( Bauer, S; Hubert, K; Knake, S; Rosenow, F; Strzelczyk, A; Voss, M, 2020)
"Zonisamide (ZNS) is a new generation antiepileptic drug (AED) used in refractory epilepsy."4.12Effectiveness of zonisamide in childhood refractory epilepsy. ( Aslan, M; Gungor, S, 2022)
" Two trials provided evidence of a dose-response relationship for this outcome."2.66Zonisamide add-on therapy for focal epilepsy. ( Behzadifar, M; Bragazzi, NL; Brigo, F; Igwe, SC; Lattanzi, S, 2020)
" Two trials provided evidence of a dose-response relationship for this outcome."2.58Zonisamide add-on therapy for focal epilepsy. ( Behzadifar, M; Bragazzi, NL; Brigo, F; Igwe, SC; Lattanzi, S, 2018)
"Pregnancy is a state where drug pharmacokinetic changes are more pronounced and more rapid than any other period of life."1.48Effect of zonisamide on refractory epilepsy during pregnancy in lamotrigine resistant kindled rats. ( Keramati, K; Mahdavi, A; Moezifar, M; Narenji Sani, R; Saberi, N, 2018)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's4 (50.00)2.80

Authors

AuthorsStudies
Aslan, M1
Gungor, S1
Hubert, K1
Knake, S1
Bauer, S1
Voss, M1
Rosenow, F1
Strzelczyk, A1
Brigo, F3
Lattanzi, S2
Igwe, SC2
Behzadifar, M2
Bragazzi, NL2
Quon, RJ1
Meisenhelter, S1
Adamovich-Zeitlin, RH1
Song, Y1
Steimel, SA1
Camp, EJ1
Testorf, ME1
MacKenzie, TA1
Gross, RE1
Lega, BC1
Sperling, MR1
Kahana, MJ1
Jobst, BC1
Tezzon, F1
Nardone, R1
Narenji Sani, R1
Keramati, K1
Saberi, N1
Moezifar, M1
Mahdavi, A1
Ortiz-Madinaveitia, S1
Serrano-Madrid, ML1
Conejo-Moreno, D1
Sagarra-Mur, D1
Jimenez-Corral, C1
Gutierrez-Alvarez, AM1

Reviews

3 reviews available for zonisamide and Drug Refractory Epilepsy

ArticleYear
Treatment of status epilepticus with zonisamide: A multicenter cohort study of 34 patients and review of literature.
    Epilepsy & behavior : E&B, 2020, Volume: 109

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Ataxia; Cohort Studies; Drug Resistant Epilepsy; Fe

2020
Zonisamide add-on therapy for focal epilepsy.
    The Cochrane database of systematic reviews, 2020, 07-24, Volume: 7

    Topics: Anticonvulsants; Drug Resistant Epilepsy; Drug Therapy, Combination; Epilepsies, Partial; Humans; In

2020
Zonisamide add-on therapy for focal epilepsy.
    The Cochrane database of systematic reviews, 2018, 10-18, Volume: 10

    Topics: Anticonvulsants; Drug Resistant Epilepsy; Drug Therapy, Combination; Epilepsies, Partial; Humans; In

2018

Other Studies

5 other studies available for zonisamide and Drug Refractory Epilepsy

ArticleYear
Effectiveness of zonisamide in childhood refractory epilepsy.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2022, Volume: 38, Issue:5

    Topics: Child; Drug Resistant Epilepsy; Epilepsies, Partial; Epilepsy; Humans; Reproducibility of Results; R

2022
Factors correlated with intracranial interictal epileptiform discharges in refractory epilepsy.
    Epilepsia, 2021, Volume: 62, Issue:2

    Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Drug Resistant Epilepsy; Electrocorticography; Fem

2021
Forced normalization and antiepileptic drugs interacting with glutamatergic neurotransmission: Caution is needed.
    Journal of the neurological sciences, 2017, 08-15, Volume: 379

    Topics: Adult; Anticonvulsants; Drug Resistant Epilepsy; Electroencephalography; Female; Glutamic Acid; Huma

2017
Effect of zonisamide on refractory epilepsy during pregnancy in lamotrigine resistant kindled rats.
    Neuroscience letters, 2018, 01-18, Volume: 664

    Topics: Animals; Animals, Newborn; Anticonvulsants; Brain; Drug Resistance; Drug Resistant Epilepsy; Female;

2018
[Early onset epileptic encephalopathy in a patient with mutation in
    Revista de neurologia, 2017, Dec-16, Volume: 65, Issue:12

    Topics: Age of Onset; Amino Acid Substitution; Anticonvulsants; Child, Preschool; Drug Resistant Epilepsy; D

2017