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zonisamide and Diabetic Neuropathies

zonisamide has been researched along with Diabetic Neuropathies in 3 studies

Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.

Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)

Research Excerpts

ExcerptRelevanceReference
"We evaluated the effects of zonisamide on inflammatory and neuropathic pain using the mouse formalin test and streptozotocin (STZ)-induced diabetic mice with a reduced withdrawal threshold to mechanical stimuli, respectively."7.74Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy. ( Murakami, T; Ono, H; Tanabe, M, 2008)
"We evaluated the effects of zonisamide on inflammatory and neuropathic pain using the mouse formalin test and streptozotocin (STZ)-induced diabetic mice with a reduced withdrawal threshold to mechanical stimuli, respectively."3.74Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy. ( Murakami, T; Ono, H; Tanabe, M, 2008)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bektas, N1
Arslan, R1
Ozturk, Y1
Moore, RA1
Wiffen, PJ1
Derry, S1
Lunn, MP1
Tanabe, M1
Murakami, T1
Ono, H1

Reviews

1 review available for zonisamide and Diabetic Neuropathies

ArticleYear
Zonisamide for neuropathic pain in adults.
    The Cochrane database of systematic reviews, 2015, Jan-22, Volume: 1

    Topics: Adult; Analgesics; Anticonvulsants; Diabetic Neuropathies; Female; Humans; Isoxazoles; Male; Middle

2015

Other Studies

2 other studies available for zonisamide and Diabetic Neuropathies

ArticleYear
Zonisamide: Antihyperalgesic efficacy, the role of serotonergic receptors on efficacy in a rat model for painful diabetic neuropathy.
    Life sciences, 2014, Jan-24, Volume: 95, Issue:1

    Topics: Animals; Anticonvulsants; Carbamazepine; Diabetic Neuropathies; Disease Models, Animal; Dose-Respons

2014
Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy.
    Journal of pharmacological sciences, 2008, Volume: 107, Issue:2

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Formaldehyde; Inflammation; Isoxazo

2008