zonisamide has been researched along with Complex Partial Epilepsy in 4 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Antiepileptics (carbamazepine, sodium valproate, zonisamide, clobazam, and topiramate), which are used for complex partial epilepsy or secondary generalized epilepsy in clinical practice, were orally administrated to kindled rats." | 3.76 | The usefulness of olfactory bulb kindling as a model for evaluation of antiepileptics. ( Akagi, M; Fujiwara, A; Ishikawa, T; Kaida, Y; Kamei, C; Takechi, K; Watanabe, Y, 2010) |
| " The most common adverse events were somnolence, headache, dizziness, and nausea during the titration phase and headache and pharyngitis during the fixed-dose assessment phase." | 2.71 | Dose-dependent safety and efficacy of zonisamide: a randomized, double-blind, placebo-controlled study in patients with refractory partial seizures. ( Bitenskyy, V; Brodie, MJ; Duncan, R; Lucas, C; Solyom, A; Vespignani, H, 2005) |
| "Zonisamide is a sulfonamide antiepilepsy drug with sodium and calcium channel-blocking actions." | 2.70 | Randomized controlled trial of zonisamide for the treatment of refractory partial-onset seizures. ( Ayala, R; Faught, E; Leppik, IE; Montouris, GG, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujiwara, A | 1 |
| Watanabe, Y | 1 |
| Takechi, K | 1 |
| Ishikawa, T | 1 |
| Kaida, Y | 1 |
| Akagi, M | 1 |
| Kamei, C | 1 |
| Noguchi, T | 1 |
| Fukatsu, N | 1 |
| Kato, H | 1 |
| Oshima, T | 1 |
| Kanemoto, K | 1 |
| Brodie, MJ | 1 |
| Duncan, R | 1 |
| Vespignani, H | 1 |
| Solyom, A | 1 |
| Bitenskyy, V | 1 |
| Lucas, C | 1 |
| Faught, E | 1 |
| Ayala, R | 1 |
| Montouris, GG | 1 |
| Leppik, IE | 1 |
2 trials available for zonisamide and Complex Partial Epilepsy
| Article | Year |
|---|---|
Dose-dependent safety and efficacy of zonisamide: a randomized, double-blind, placebo-controlled study in patients with refractory partial seizures.
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Child; Dose-Response Relationship, Drug; Doub | 2005 |
Randomized controlled trial of zonisamide for the treatment of refractory partial-onset seizures.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Cross-Over Studies; Dose-Response Relationship, Drug; Doub | 2001 |
2 other studies available for zonisamide and Complex Partial Epilepsy
| Article | Year |
|---|---|
The usefulness of olfactory bulb kindling as a model for evaluation of antiepileptics.
Topics: Amygdala; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Disease Models, Animal; Electri | 2010 |
Impact of antiepileptic drugs on genesis of psychosis.
Topics: Adolescent; Adult; Anticonvulsants; Epilepsy, Complex Partial; Female; Follow-Up Studies; Humans; In | 2012 |