zonisamide has been researched along with Cerebral Ischemia in 3 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Zonisamide (ZNS) has shown anti-apoptosis effects in recent studies." | 5.62 | Neuroprotective effects of zonisamide on cerebral ischemia injury via inhibition of neuronal apoptosis. ( Chen, R; Chen, Y; He, J; He, W; Xie, Y; Yang, Y; Zhang, X, 2021) |
| "Zonisamide (ZNS) has shown anti-apoptosis effects in recent studies." | 1.62 | Neuroprotective effects of zonisamide on cerebral ischemia injury via inhibition of neuronal apoptosis. ( Chen, R; Chen, Y; He, J; He, W; Xie, Y; Yang, Y; Zhang, X, 2021) |
| "When zonisamide (75 mg/kg) was administered i." | 1.29 | Zonisamide reduces hypoxic-ischemic brain damage in neonatal rats irrespective of its anticonvulsive effect. ( Hattori, H; Hayakawa, T; Higuchi, Y; Nigami, H, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| He, J | 1 |
| Zhang, X | 1 |
| He, W | 1 |
| Xie, Y | 1 |
| Chen, Y | 1 |
| Yang, Y | 1 |
| Chen, R | 1 |
| Costa, C | 1 |
| Tozzi, A | 1 |
| Siliquini, S | 1 |
| Galletti, F | 1 |
| Cardaioli, G | 1 |
| Tantucci, M | 1 |
| Pisani, F | 1 |
| Calabresi, P | 1 |
| Hayakawa, T | 1 |
| Higuchi, Y | 1 |
| Nigami, H | 1 |
| Hattori, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Neuroprotective Effect of Dapsone in Patients With Aneurysmal Subarachnoid Hemorrhage: Prospective, Randomized, Double-Blinded, Placebo-Controlled, Clinical Trial[NCT05131295] | Phase 3 | 49 participants (Actual) | Interventional | 2007-09-05 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for zonisamide and Cerebral Ischemia
| Article | Year |
|---|---|
Neuroprotective effects of zonisamide on cerebral ischemia injury via inhibition of neuronal apoptosis.
Topics: Animals; Apoptosis; Brain Ischemia; Infarction, Middle Cerebral Artery; Mice; Neuroprotective Agents | 2021 |
A critical role of NO/cGMP/PKG dependent pathway in hippocampal post-ischemic LTP: modulation by zonisamide.
Topics: Animals; Anticonvulsants; Brain Ischemia; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease | 2011 |
Zonisamide reduces hypoxic-ischemic brain damage in neonatal rats irrespective of its anticonvulsive effect.
Topics: Animals; Anticonvulsants; Body Temperature; Brain; Brain Ischemia; Electroencephalography; Hippocamp | 1994 |