zonisamide has been researched along with Cardiomegaly in 2 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tian, JH | 2 |
| Wu, Q | 2 |
| He, YX | 2 |
| Shen, QY | 1 |
| Rekep, M | 1 |
| Zhang, GP | 2 |
| Luo, JD | 2 |
| Xue, Q | 2 |
| Liu, YH | 2 |
| Huang, YY | 1 |
| Huang, YQ | 1 |
| Yu, XY | 1 |
2 other studies available for zonisamide and Cardiomegaly
| Article | Year |
|---|---|
Zonisamide, an antiepileptic drug, alleviates diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress.
Topics: Animals; Anticonvulsants; Apoptosis; Blood Glucose; Body Weight; Cardiomegaly; Diabetes Mellitus, Ty | 2021 |
Zonisamide alleviates cardiac hypertrophy in rats by increasing Hrd1 expression and inhibiting endoplasmic reticulum stress.
Topics: Animals; Aorta, Abdominal; Apoptosis; Cardiomegaly; Endoplasmic Reticulum Stress; Endoplasmic Reticu | 2021 |