zonisamide has been researched along with Benign Infantile Myoclonic Epilepsy in 10 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the efficacy and safety of zonisamide (ZNS) adjunctive therapy in children with intractable epilepsy to existing antiepileptic drugs (AEDs)." | 9.14 | Efficacy and tolerability of adjunctive therapy with zonisamide in childhood intractable epilepsy. ( Kang, HC; Kim, HD; Lee, JS; Lee, YJ; Seo, JH, 2010) |
| "This study investigated the efficacy and safety of zonisamide (ZNS) adjunctive therapy in children with intractable epilepsy to existing antiepileptic drugs (AEDs)." | 5.14 | Efficacy and tolerability of adjunctive therapy with zonisamide in childhood intractable epilepsy. ( Kang, HC; Kim, HD; Lee, JS; Lee, YJ; Seo, JH, 2010) |
| "Zonisamide (ZNS) is a broad-spectrum antiepileptic drug in both animal models of epilepsy and patients with epilepsy." | 4.80 | Zonisamide. ( Leppik, IE, 1999) |
| "Vigabatrin has shown promise in treating IS patients, particularly those with tuberous sclerosis." | 2.42 | Pharmacologic treatment of the catastrophic epilepsies. ( Conry, JA, 2004) |
| "Severe myoclonic epilepsy of infants usually worsens with lamotrigine, but occasionally, children improve." | 2.40 | Myoclonus and epilepsy in childhood: a review of treatment with valproate, ethosuximide, lamotrigine and zonisamide. ( Wallace, SJ, 1998) |
| "The recommended treatment for juvenile myoclonic epilepsy (JME) is valproate (VPA)." | 1.32 | Efficacy and tolerability of zonisamide in juvenile myoclonic epilepsy. ( Hardison, H; Khurana, DS; Kothare, SV; Legido, A; Melvin, JJ; Valencia, I, 2004) |
| "Zonisamide was given at doses of 100-600 mg/day for a period of 2 to 3 years." | 1.30 | Zonisamide for progressive myoclonus epilepsy: long-term observations in seven patients. ( Ben-Menachem, E; Kyllerman, M, 1998) |
| "Two patients with progressive myoclonus epilepsy of the Unverricht-Lundborg type and with intractable seizures in spite of standard anticonvulsant regimens were treated with zonisamide." | 1.27 | Progressive myoclonus epilepsy treated with zonisamide. ( Gumnit, RJ; Henry, TR; Jacobs, M; Leppik, IE, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, YJ | 1 |
| Kang, HC | 1 |
| Seo, JH | 1 |
| Lee, JS | 1 |
| Kim, HD | 1 |
| Kelemen, A | 1 |
| Rásonyl, G | 1 |
| Neuwirth, M | 1 |
| Barcs, G | 1 |
| Szucs, A | 1 |
| Jakus, R | 1 |
| Fabó, D | 1 |
| Juhos, V | 1 |
| Pálfy, B | 1 |
| Halász, P | 1 |
| Conry, JA | 1 |
| Kothare, SV | 1 |
| Valencia, I | 1 |
| Khurana, DS | 1 |
| Hardison, H | 1 |
| Melvin, JJ | 1 |
| Legido, A | 1 |
| Kyllerman, M | 1 |
| Ben-Menachem, E | 1 |
| Wallace, SJ | 1 |
| Leppik, IE | 2 |
| Kanazawa, O | 1 |
| Sander, JW | 1 |
| Hart, YM | 1 |
| Duncan, JS | 1 |
| Shorvon, SD | 1 |
| Henry, TR | 1 |
| Gumnit, RJ | 1 |
| Jacobs, M | 1 |
4 reviews available for zonisamide and Benign Infantile Myoclonic Epilepsy
| Article | Year |
|---|---|
Pharmacologic treatment of the catastrophic epilepsies.
Topics: Anticonvulsants; Child, Preschool; Epilepsies, Myoclonic; Epilepsy; Fructose; Humans; Infant; Isoxaz | 2004 |
Myoclonus and epilepsy in childhood: a review of treatment with valproate, ethosuximide, lamotrigine and zonisamide.
Topics: Anticonvulsants; Child; Child, Preschool; Epilepsies, Myoclonic; Ethosuximide; Humans; Infant; Isoxa | 1998 |
Zonisamide.
Topics: Adult; Animals; Anticonvulsants; Clinical Trials as Topic; Disease Models, Animal; Drug Administrati | 1999 |
Refractory grand mal seizures with onset during infancy including severe myoclonic epilepsy in infancy.
Topics: Anticonvulsants; Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic; Humans; Infant; Isoxazoles; Zonisami | 2001 |
1 trial available for zonisamide and Benign Infantile Myoclonic Epilepsy
| Article | Year |
|---|---|
Efficacy and tolerability of adjunctive therapy with zonisamide in childhood intractable epilepsy.
Topics: Adolescent; Anticonvulsants; Chemotherapy, Adjuvant; Child; Child, Preschool; Dose-Response Relation | 2010 |
5 other studies available for zonisamide and Benign Infantile Myoclonic Epilepsy
| Article | Year |
|---|---|
Our clinical experience with zonisamide in resistant generalized epilepsy syndromes.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Confusion; Disorders of Excessive Somno | 2011 |
Efficacy and tolerability of zonisamide in juvenile myoclonic epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Child; Dose-Response Relationship, Drug; Drug Interactions; Drug | 2004 |
Zonisamide for progressive myoclonus epilepsy: long-term observations in seven patients.
Topics: Adult; Anticonvulsants; Epilepsies, Myoclonic; Female; Humans; Isoxazoles; Male; Middle Aged; Time F | 1998 |
Zonisamide usage.
Topics: Epilepsies, Myoclonic; Humans; Isoxazoles; Kidney Calculi; Oxazoles; Zonisamide | 1989 |
Progressive myoclonus epilepsy treated with zonisamide.
Topics: Adult; Epilepsies, Myoclonic; Humans; Isoxazoles; Male; Oxazoles; Zonisamide | 1988 |