zonisamide has been researched along with Allodynia in 4 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the ability of zonisamide (Zonegran) to relieve thermal hyperalgesia and/or mechanical allodynia in the chronic constriction injury model of neuropathic pain." | 7.72 | The effect of systemic zonisamide (Zonegran) on thermal hyperalgesia and mechanical allodynia in rats with an experimental mononeuropathy. ( Azevedo, MI; Chalfoun, AG; Denson, DD; Hord, AH, 2003) |
| " We have evaluated the effects and investigated the possible mechanisms of action of zonisamide, an antiepileptic drug, on thermal hyperalgesia and tactile allodynia in a murine chronic pain model that was prepared by partial ligation of the sciatic nerve." | 3.73 | Centrally mediated antihyperalgesic and antiallodynic effects of zonisamide following partial nerve injury in the mouse. ( Honda, M; Ono, H; Sakaue, A; Takasu, K; Tanabe, M, 2005) |
| "We studied the ability of zonisamide (Zonegran) to relieve thermal hyperalgesia and/or mechanical allodynia in the chronic constriction injury model of neuropathic pain." | 3.72 | The effect of systemic zonisamide (Zonegran) on thermal hyperalgesia and mechanical allodynia in rats with an experimental mononeuropathy. ( Azevedo, MI; Chalfoun, AG; Denson, DD; Hord, AH, 2003) |
| "Cellular mechanisms underlying neuropathic pain remain mostly elusive, and partial pain relief can be achieved in a limited number of patients by antidepressants, anticonvulsants topical anesthetics, and others." | 1.56 | Zonisamide ameliorates neuropathic pain partly by suppressing microglial activation in the spinal cord in a mouse model. ( Imagama, S; Inoue, T; Ishiguro, N; Ito, M; Kanbara, S; Kiryu-Seo, S; Kiyama, H; Konishi, H; Koshimizu, H; Masuda, A; Nakashima, H; Ohkawara, B; Ohno, K; Ota, K; Sayo, A; Tomita, H, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koshimizu, H | 1 |
| Ohkawara, B | 1 |
| Nakashima, H | 1 |
| Ota, K | 1 |
| Kanbara, S | 1 |
| Inoue, T | 1 |
| Tomita, H | 1 |
| Sayo, A | 1 |
| Kiryu-Seo, S | 1 |
| Konishi, H | 1 |
| Ito, M | 1 |
| Masuda, A | 1 |
| Ishiguro, N | 1 |
| Imagama, S | 1 |
| Kiyama, H | 1 |
| Ohno, K | 1 |
| Bektas, N | 1 |
| Arslan, R | 1 |
| Ozturk, Y | 1 |
| Hord, AH | 1 |
| Denson, DD | 1 |
| Chalfoun, AG | 1 |
| Azevedo, MI | 1 |
| Tanabe, M | 1 |
| Sakaue, A | 1 |
| Takasu, K | 1 |
| Honda, M | 1 |
| Ono, H | 1 |
4 other studies available for zonisamide and Allodynia
| Article | Year |
|---|---|
Zonisamide ameliorates neuropathic pain partly by suppressing microglial activation in the spinal cord in a mouse model.
Topics: Animals; Anticonvulsants; Cytokines; Disease Models, Animal; Hyperalgesia; Male; Mice; Microglia; Ne | 2020 |
Zonisamide: Antihyperalgesic efficacy, the role of serotonergic receptors on efficacy in a rat model for painful diabetic neuropathy.
Topics: Animals; Anticonvulsants; Carbamazepine; Diabetic Neuropathies; Disease Models, Animal; Dose-Respons | 2014 |
The effect of systemic zonisamide (Zonegran) on thermal hyperalgesia and mechanical allodynia in rats with an experimental mononeuropathy.
Topics: Animals; Anticonvulsants; Behavior, Animal; Constriction; Dose-Response Relationship, Drug; Hot Temp | 2003 |
Centrally mediated antihyperalgesic and antiallodynic effects of zonisamide following partial nerve injury in the mouse.
Topics: Animals; Antioxidants; Central Nervous System; Disease Models, Animal; Dose-Response Relationship, D | 2005 |