zonisamide has been researched along with Alcohol Abuse in 6 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Zonisamide is an anticonvulsant medication with GABAergic, glutamatergic, and monoaminergic effects." | 2.75 | Placebo-controlled trial of zonisamide for the treatment of alcohol dependence. ( Arias, AJ; Covault, J; Feinn, R; Kranzler, HR; Oncken, C, 2010) |
| "Diazepam was administered using a similar regimen (from 130-50 mg/day tapering to 5-15 mg/day)." | 2.75 | Zonisamide versus diazepam in the treatment of alcohol withdrawal syndrome. ( Alamo, C; Ferre, F; Jiménez-Arriero, MÁ; López-Muñoz, F; Martínez-Gras, I; Pascual, JM; Ponce, G; Rubio, G, 2010) |
| "The comorbidity between alcohol use disorder and post-traumatic stress disorder represents a serious health care burden with few effective treatment options." | 1.56 | Evaluation of the effect of doxasozin and zonisamide on voluntary ethanol intake in mice that experienced chronic intermittent ethanol exposure and stress. ( Becker, HC; Carper, BA; Lopez, MF; Nolen, TL; Reasons, SE; Williams, RL, 2020) |
| "Zonisamide is a new anti-epileptic drug whose mechanism of action is associated with neurotransmission systems also involved in the pathogenesis of addiction." | 1.46 | The Impact of Zonisamide on the Development and Course of Alcohol Dependence in Rabbits. A pharmaco-EEG study. ( Kordala, A; Krupa-Burtnik, A; Pietrzak, B; Zwierzynska, E, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Pietrzak, B | 2 |
| Krupa-Burtnik, A | 2 |
| Zwierzyńska, E | 2 |
| Lopez, MF | 1 |
| Reasons, SE | 1 |
| Carper, BA | 1 |
| Nolen, TL | 1 |
| Williams, RL | 1 |
| Becker, HC | 1 |
| Kordala, A | 1 |
| Coelho, R | 1 |
| Rodrigues, S | 1 |
| Gaspar, R | 1 |
| Silva, R | 1 |
| Lopes, J | 1 |
| Macedo, G | 1 |
| Arias, AJ | 1 |
| Feinn, R | 1 |
| Oncken, C | 1 |
| Covault, J | 1 |
| Kranzler, HR | 1 |
| Rubio, G | 1 |
| López-Muñoz, F | 1 |
| Ponce, G | 1 |
| Pascual, JM | 1 |
| Martínez-Gras, I | 1 |
| Ferre, F | 1 |
| Jiménez-Arriero, MÁ | 1 |
| Alamo, C | 1 |
2 trials available for zonisamide and Alcohol Abuse
| Article | Year |
|---|---|
Placebo-controlled trial of zonisamide for the treatment of alcohol dependence.
Topics: Adolescent; Adult; Aged; Alcoholism; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle A | 2010 |
Zonisamide versus diazepam in the treatment of alcohol withdrawal syndrome.
Topics: Adult; Alcoholism; Anticonvulsants; Diazepam; Dose-Response Relationship, Drug; Ethanol; Female; Hum | 2010 |
4 other studies available for zonisamide and Alcohol Abuse
| Article | Year |
|---|---|
The Effect of Zonisamide and Ethanol on Various Types of Memory in Rats.
Topics: Alcoholism; Animals; Anticonvulsants; Ethanol; Hippocampus; Rats; Rats, Wistar; Zonisamide | 2023 |
Evaluation of the effect of doxasozin and zonisamide on voluntary ethanol intake in mice that experienced chronic intermittent ethanol exposure and stress.
Topics: Alcohol Drinking; Alcoholism; Animals; Doxazosin; Ethanol; Female; Male; Mice; Mice, Inbred C57BL; S | 2020 |
The Impact of Zonisamide on the Development and Course of Alcohol Dependence in Rabbits. A pharmaco-EEG study.
Topics: Administration, Oral; Alcoholism; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electr | 2017 |
Zonisamide-induced Acute-on-Chronic Liver Failure: First Report.
Topics: Acute-On-Chronic Liver Failure; Adult; Alcoholism; Anticonvulsants; Epilepsy; Female; Humans; Isoxaz | 2016 |