zonisamide has been researched along with Adolescent Myoclonic Epilepsy in 7 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 30-year-old woman with primary generalized tonic-clonic seizures and myoclonic jerks was taking zonisamide 200 mg daily as her sole antiepileptic agent when she conceived." | 7.74 | Zonisamide concentrations during pregnancy. ( Bell, WL; Oles, KS, 2008) |
| "A 30-year-old woman with primary generalized tonic-clonic seizures and myoclonic jerks was taking zonisamide 200 mg daily as her sole antiepileptic agent when she conceived." | 3.74 | Zonisamide concentrations during pregnancy. ( Bell, WL; Oles, KS, 2008) |
| " Mean duration of zonisamide therapy was 55 weeks (range 5-168 weeks) and mean maintenance dosage was 7." | 2.73 | Long-term use of zonisamide in refractory childhood-onset epilepsy. ( Holthausen, H; Kluger, G; Zsoter, A, 2008) |
| "Juvenile myoclonic epilepsy is a common idiopathic generalized epileptic syndrome that includes generalized myoclonic seizures and commonly generalized tonic-clonic and generalized absence seizures." | 2.45 | The first line of therapy in a girl with juvenile myoclonic epilepsy: should it be valproate or a new agent? ( Abou-Khalil, B; Montouris, G, 2009) |
| "Under lamotrigine, seizure aggravation was observed in 15 patients (two patients during levetiracetam, one patient during zonisamide, none during phenobarbital and valproic acid)." | 1.62 | Risk factors of paradoxical reactions to anti-seizure medication in genetic generalized epilepsy. ( Beier, CP; Gesche, J; Hjalgrim, H; Rubboli, G, 2021) |
| "The recommended treatment for juvenile myoclonic epilepsy (JME) is valproate (VPA)." | 1.32 | Efficacy and tolerability of zonisamide in juvenile myoclonic epilepsy. ( Hardison, H; Khurana, DS; Kothare, SV; Legido, A; Melvin, JJ; Valencia, I, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Gesche, J | 1 |
| Hjalgrim, H | 1 |
| Rubboli, G | 1 |
| Beier, CP | 1 |
| Oles, KS | 1 |
| Bell, WL | 1 |
| Montouris, G | 1 |
| Abou-Khalil, B | 1 |
| Szaflarski, JP | 1 |
| Kothare, SV | 1 |
| Valencia, I | 1 |
| Khurana, DS | 1 |
| Hardison, H | 1 |
| Melvin, JJ | 1 |
| Legido, A | 1 |
| O'Rourke, D | 1 |
| Flynn, C | 1 |
| White, M | 1 |
| Doherty, C | 1 |
| Delanty, N | 1 |
| Kluger, G | 1 |
| Zsoter, A | 1 |
| Holthausen, H | 1 |
1 review available for zonisamide and Adolescent Myoclonic Epilepsy
| Article | Year |
|---|---|
The first line of therapy in a girl with juvenile myoclonic epilepsy: should it be valproate or a new agent?
Topics: Anticonvulsants; Congenital Abnormalities; Delayed-Action Preparations; Drug Design; Epilepsy, Gener | 2009 |
1 trial available for zonisamide and Adolescent Myoclonic Epilepsy
| Article | Year |
|---|---|
Long-term use of zonisamide in refractory childhood-onset epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Drug Administration Schedule; Drug Eval | 2008 |
5 other studies available for zonisamide and Adolescent Myoclonic Epilepsy
| Article | Year |
|---|---|
Risk factors of paradoxical reactions to anti-seizure medication in genetic generalized epilepsy.
Topics: Adult; Anticonvulsants; Epilepsy, Generalized; Humans; Lamotrigine; Levetiracetam; Myoclonic Epileps | 2021 |
Zonisamide concentrations during pregnancy.
Topics: Adult; Anticonvulsants; Female; Humans; Isoxazoles; Myoclonic Epilepsy, Juvenile; Pregnancy; Pregnan | 2008 |
Effects of zonisamide on the electroencephalogram of a patient with juvenile myoclonic epilepsy.
Topics: Adult; Anticonvulsants; Electroencephalography; Humans; Isoxazoles; Male; Myoclonic Epilepsy, Juveni | 2004 |
Efficacy and tolerability of zonisamide in juvenile myoclonic epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Child; Dose-Response Relationship, Drug; Drug Interactions; Drug | 2004 |
Potential efficacy of zonisamide in refractory juvenile myoclonic epilepsy: retrospective evidence from an Irish compassionate-use case series.
Topics: Adolescent; Adult; Anticonvulsants; Empathy; Female; Humans; Ireland; Isoxazoles; Myoclonic Epilepsy | 2007 |