Page last updated: 2024-11-05

zonisamide and Acidosis, Renal Tubular

zonisamide has been researched along with Acidosis, Renal Tubular in 4 studies

Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.

Acidosis, Renal Tubular: A group of genetic disorders of the KIDNEY TUBULES characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic ACIDOSIS. Defective renal acidification of URINE (proximal tubules) or low renal acid excretion (distal tubules) can lead to complications such as HYPOKALEMIA, hypercalcinuria with NEPHROLITHIASIS and NEPHROCALCINOSIS, and RICKETS.

Research Excerpts

ExcerptRelevanceReference
"A 3-year-old neutered male golden retriever administered zonisamide for the treatment of seizures showed lethargy and had normal anion gap metabolic acidosis with hypokalaemia, hyperchloremia, and alkaline urine."8.12Distal renal tubular acidosis and lethargy associated with zonisamide treatment in a dog with idiopathic epilepsy. ( Akashi, N; Hata, A; Itoi, T; Kanda, T; Kutara, K; Miyama, TS; Shimizu, Y; Sugimoto, K, 2022)
"A 3-year-old neutered male golden retriever administered zonisamide for the treatment of seizures showed lethargy and had normal anion gap metabolic acidosis with hypokalaemia, hyperchloremia, and alkaline urine."4.12Distal renal tubular acidosis and lethargy associated with zonisamide treatment in a dog with idiopathic epilepsy. ( Akashi, N; Hata, A; Itoi, T; Kanda, T; Kutara, K; Miyama, TS; Shimizu, Y; Sugimoto, K, 2022)
"Distal renal tubular acidosis was diagnosed."1.31Renal tubular acidosis associated with zonisamide therapy. ( Gondo, K; Hara, T; Ikeda, K; Inoue, T; Kaku, Y; Kira, R, 2000)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Itoi, T1
Akashi, N1
Shimizu, Y1
Sugimoto, K1
Hata, A1
Kutara, K1
Miyama, TS1
Kanda, T1
MacMahon, T1
Kelly, YP1
Mirza, NS1
Alfirevic, A1
Jorgensen, A1
Marson, AG1
Pirmohamed, M1
Inoue, T1
Kira, R1
Kaku, Y1
Ikeda, K1
Gondo, K1
Hara, T1

Other Studies

4 other studies available for zonisamide and Acidosis, Renal Tubular

ArticleYear
Distal renal tubular acidosis and lethargy associated with zonisamide treatment in a dog with idiopathic epilepsy.
    Veterinary medicine and science, 2022, Volume: 8, Issue:6

    Topics: Acidosis, Renal Tubular; Animals; Bicarbonates; Dog Diseases; Dogs; Epilepsy; Lethargy; Male; Zonisa

2022
Zonisamide-induced distal renal tubular acidosis and critical hypokalaemia.
    BMJ case reports, 2023, Apr-11, Volume: 16, Issue:4

    Topics: Acidosis; Acidosis, Renal Tubular; Female; Humans; Hypokalemia; Muscle Weakness; Zonisamide

2023
Metabolic acidosis with topiramate and zonisamide: an assessment of its severity and predictors.
    Pharmacogenetics and genomics, 2011, Volume: 21, Issue:5

    Topics: Acid-Base Equilibrium; Acidosis, Renal Tubular; Adult; Aged; Carbonic Anhydrase Inhibitors; Carbonic

2011
Renal tubular acidosis associated with zonisamide therapy.
    Epilepsia, 2000, Volume: 41, Issue:12

    Topics: Acidosis, Renal Tubular; Anticonvulsants; Blood Gas Analysis; Child; Electrolytes; Epilepsies, Parti

2000