Page last updated: 2024-11-05

zolpidem and Tauopathies

zolpidem has been researched along with Tauopathies in 2 studies

Zolpidem: An imidazopyridine derivative and short-acting GABA-A receptor agonist that is used for the treatment of INSOMNIA.
zolpidem : An imidazo[1,2-a]pyridine compound having a 4-tolyl group at the 2-position, an N,N-dimethylcarbamoylmethyl group at the 3-position and a methyl substituent at the 6-position.

Tauopathies: Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with ALZHEIMER DISEASE; DEMENTIA; PARKINSONIAN DISORDERS; progressive supranuclear palsy (SUPRANUCLEAR PALSY, PROGRESSIVE); and corticobasal degeneration.

Research Excerpts

ExcerptRelevanceReference
"Tauopathies are also associated with deficits in synaptic plasticity such as long-term potentiation (LTP), but the specific role of tau in the manifestation of these deficiencies is not well-understood."1.39Tau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments. ( Cain, P; Franke, TF; Hoeffer, CA; Krishnamurthy, P; Levenga, J; Rajamohamedsait, H; Sigurdsson, EM; Wong, H, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Keenan, RJ1
Daykin, H1
Chu, J1
Cornthwaite-Duncan, L1
Allocca, G1
Hoyer, D1
Jacobson, LH1
Levenga, J1
Krishnamurthy, P1
Rajamohamedsait, H1
Wong, H1
Franke, TF1
Cain, P1
Sigurdsson, EM1
Hoeffer, CA1

Other Studies

2 other studies available for zolpidem and Tauopathies

ArticleYear
Differential sleep/wake response and sex differences following acute suvorexant, MK-1064 and zolpidem administration in the rTg4510 mouse model of tauopathy.
    British journal of pharmacology, 2022, Volume: 179, Issue:13

    Topics: Animals; Azepines; Disease Models, Animal; Female; Hypnotics and Sedatives; Male; Mice; Mice, Transg

2022
Tau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments.
    Acta neuropathologica communications, 2013, Jul-11, Volume: 1

    Topics: Animals; Cell Count; Cerebral Cortex; Disease Models, Animal; GABA-A Receptor Agonists; GABAergic Ne

2013