zolpidem has been researched along with Tauopathies in 2 studies
Zolpidem: An imidazopyridine derivative and short-acting GABA-A receptor agonist that is used for the treatment of INSOMNIA.
zolpidem : An imidazo[1,2-a]pyridine compound having a 4-tolyl group at the 2-position, an N,N-dimethylcarbamoylmethyl group at the 3-position and a methyl substituent at the 6-position.
Tauopathies: Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with ALZHEIMER DISEASE; DEMENTIA; PARKINSONIAN DISORDERS; progressive supranuclear palsy (SUPRANUCLEAR PALSY, PROGRESSIVE); and corticobasal degeneration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tauopathies are also associated with deficits in synaptic plasticity such as long-term potentiation (LTP), but the specific role of tau in the manifestation of these deficiencies is not well-understood." | 1.39 | Tau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments. ( Cain, P; Franke, TF; Hoeffer, CA; Krishnamurthy, P; Levenga, J; Rajamohamedsait, H; Sigurdsson, EM; Wong, H, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Keenan, RJ | 1 |
| Daykin, H | 1 |
| Chu, J | 1 |
| Cornthwaite-Duncan, L | 1 |
| Allocca, G | 1 |
| Hoyer, D | 1 |
| Jacobson, LH | 1 |
| Levenga, J | 1 |
| Krishnamurthy, P | 1 |
| Rajamohamedsait, H | 1 |
| Wong, H | 1 |
| Franke, TF | 1 |
| Cain, P | 1 |
| Sigurdsson, EM | 1 |
| Hoeffer, CA | 1 |
2 other studies available for zolpidem and Tauopathies
| Article | Year |
|---|---|
Differential sleep/wake response and sex differences following acute suvorexant, MK-1064 and zolpidem administration in the rTg4510 mouse model of tauopathy.
Topics: Animals; Azepines; Disease Models, Animal; Female; Hypnotics and Sedatives; Male; Mice; Mice, Transg | 2022 |
Tau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments.
Topics: Animals; Cell Count; Cerebral Cortex; Disease Models, Animal; GABA-A Receptor Agonists; GABAergic Ne | 2013 |