zolpidem has been researched along with Stroke in 12 studies
Zolpidem: An imidazopyridine derivative and short-acting GABA-A receptor agonist that is used for the treatment of INSOMNIA.
zolpidem : An imidazo[1,2-a]pyridine compound having a 4-tolyl group at the 2-position, an N,N-dimethylcarbamoylmethyl group at the 3-position and a methyl substituent at the 6-position.
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| "During 15 years, 23 clinical reports and 6 studies have demonstrated associations between sub-sedative doses of zolpidem and recoveries from brain damage due to strokes, trauma and hypoxia." | 8.95 | A review of the evidence of zolpidem efficacy in neurological disability after brain damage due to stroke, trauma and hypoxia: A justification of further clinical trials. ( Clauss, RP; Sutton, JA, 2017) |
| "Objective To evaluate the effects of zolpidem on functional recovery in a rat model of acute ischemic stroke." | 7.88 | Effect of zolpidem on functional recovery in a rat model of ischemic stroke. ( Chae, SW; Choi, HY; Chun, SW; Lee, YT; Oh, MK; Park, YH; Park, YS; Shin, HS; Yoon, KJ, 2018) |
| "To evaluate the relationship between the use of zolpidem and risk of subsequent stroke in Taiwanese patients." | 7.79 | Relationship between zolpidem use and stroke risk: a Taiwanese population-based case-control study. ( Chang, YJ; Huang, WS; Kao, CH; Lin, CC; Muo, CH; Sung, FC; Tsai, CH, 2013) |
| "Zolpidem was associated with a dramatic improvement in apathy, as assessed with the Apathy Inventory and the Behavioral Dysexecutive Syndrome Inventory." | 5.39 | Transient improvement of poststroke apathy with zolpidem: a single-case, placebo-controlled double-blind study. ( Arnould, A; Autret, K; Azouvi, P; Mathieu, S, 2013) |
| "During 15 years, 23 clinical reports and 6 studies have demonstrated associations between sub-sedative doses of zolpidem and recoveries from brain damage due to strokes, trauma and hypoxia." | 4.95 | A review of the evidence of zolpidem efficacy in neurological disability after brain damage due to stroke, trauma and hypoxia: A justification of further clinical trials. ( Clauss, RP; Sutton, JA, 2017) |
| "Pharmacotherapy of aphasia had been discussed for the last twenty years with first bromocriptine and amphetamine and then serotoninergic, GABAergic and cholinergic agents." | 4.84 | Pharmacotherapy of aphasia: myth or reality? ( de Boissezon, X; de Boysson, C; Démonet, JF; Peran, P, 2007) |
| "Objective To evaluate the effects of zolpidem on functional recovery in a rat model of acute ischemic stroke." | 3.88 | Effect of zolpidem on functional recovery in a rat model of ischemic stroke. ( Chae, SW; Choi, HY; Chun, SW; Lee, YT; Oh, MK; Park, YH; Park, YS; Shin, HS; Yoon, KJ, 2018) |
| "Sutton and Clauss presented a detailed review about the effectiveness of zolpidem, discussing recoveries from brain damage due to strokes, trauma and hypoxia." | 3.88 | Zolpidem efficacy and safety in disorders of consciousness. ( Estévez, M; Machado, C; Rodriguez-Rojas, R, 2018) |
| "To evaluate the relationship between the use of zolpidem and risk of subsequent stroke in Taiwanese patients." | 3.79 | Relationship between zolpidem use and stroke risk: a Taiwanese population-based case-control study. ( Chang, YJ; Huang, WS; Kao, CH; Lin, CC; Muo, CH; Sung, FC; Tsai, CH, 2013) |
| "The study investigates the effect of zolpidem (CAS 82626-48-0) on brain injuries and cerebellar diaschisis." | 3.72 | Effect of zolpidem on brain injury and diaschisis as detected by 99mTc HMPAO brain SPECT in humans. ( Clauss, RP; Nel, WH, 2004) |
| "Ischaemic stroke is the leading cause of severe long-term disability yet lacks drug therapies that promote the repair phase of recovery." | 1.43 | Enhanced phasic GABA inhibition during the repair phase of stroke: a novel therapeutic target. ( Badgely, C; Bliss, TM; Farzampour, Z; Hamilton, SA; Hiu, T; Huguenard, JR; Lemmens, R; Liang, X; Micheva, KD; Nishiyama, Y; O'Rourke, N; Olson, A; Paz, JT; Smith, SJ; Steinberg, GK; Tran, KV; Wang, EH; Wang, G, 2016) |
| "Zolpidem is a non-benzodiazepine drug used for the therapy of insomnia, which has selectivity for stimulating the effect of GABA-A receptors." | 1.39 | Zolpidem induces paradoxical metabolic and vascular changes in a patient with PVS. ( Alvarez, L; Carballo, M; Carrick, FR; Chinchilla, M; DeFina, P; Estevez, M; Machado, C; Pavon, N; Perez-Nellar, J; Rodriguez-Rojas, R, 2013) |
| "Zolpidem was associated with a dramatic improvement in apathy, as assessed with the Apathy Inventory and the Behavioral Dysexecutive Syndrome Inventory." | 1.39 | Transient improvement of poststroke apathy with zolpidem: a single-case, placebo-controlled double-blind study. ( Arnould, A; Autret, K; Azouvi, P; Mathieu, S, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 9 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sutton, JA | 1 |
| Clauss, RP | 3 |
| Oh, MK | 1 |
| Yoon, KJ | 1 |
| Lee, YT | 1 |
| Chae, SW | 1 |
| Choi, HY | 1 |
| Shin, HS | 1 |
| Park, YH | 1 |
| Chun, SW | 1 |
| Park, YS | 1 |
| Machado, C | 2 |
| Estévez, M | 2 |
| Rodriguez-Rojas, R | 2 |
| Huang, WS | 1 |
| Tsai, CH | 1 |
| Lin, CC | 1 |
| Muo, CH | 1 |
| Sung, FC | 1 |
| Chang, YJ | 1 |
| Kao, CH | 1 |
| Alvarez, L | 1 |
| Carballo, M | 1 |
| Perez-Nellar, J | 1 |
| Pavon, N | 1 |
| Chinchilla, M | 1 |
| Carrick, FR | 1 |
| DeFina, P | 1 |
| Horton, JC | 1 |
| Hiu, T | 1 |
| Farzampour, Z | 1 |
| Paz, JT | 1 |
| Wang, EH | 1 |
| Badgely, C | 1 |
| Olson, A | 1 |
| Micheva, KD | 1 |
| Wang, G | 1 |
| Lemmens, R | 1 |
| Tran, KV | 1 |
| Nishiyama, Y | 1 |
| Liang, X | 1 |
| Hamilton, SA | 1 |
| O'Rourke, N | 1 |
| Smith, SJ | 1 |
| Huguenard, JR | 1 |
| Bliss, TM | 1 |
| Steinberg, GK | 1 |
| Hall, SD | 1 |
| Yamawaki, N | 1 |
| Fisher, AE | 1 |
| Woodhall, GL | 1 |
| Stanford, IM | 1 |
| Autret, K | 1 |
| Arnould, A | 1 |
| Mathieu, S | 1 |
| Azouvi, P | 1 |
| Cohen, L | 1 |
| Chaaban, B | 1 |
| Habert, MO | 1 |
| Nel, WH | 1 |
| de Boissezon, X | 1 |
| Peran, P | 1 |
| de Boysson, C | 1 |
| Démonet, JF | 1 |
2 reviews available for zolpidem and Stroke
| Article | Year |
|---|---|
A review of the evidence of zolpidem efficacy in neurological disability after brain damage due to stroke, trauma and hypoxia: A justification of further clinical trials.
Topics: Brain Injuries; Humans; Hypnotics and Sedatives; Hypoxia; Nervous System Diseases; Pyridines; Stroke | 2017 |
Pharmacotherapy of aphasia: myth or reality?
Topics: Amphetamine; Aphasia; Bromocriptine; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; | 2007 |
10 other studies available for zolpidem and Stroke
| Article | Year |
|---|---|
Effect of zolpidem on functional recovery in a rat model of ischemic stroke.
Topics: Animals; Brain Ischemia; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Drug Administrat | 2018 |
Zolpidem efficacy and safety in disorders of consciousness.
Topics: Brain; Consciousness; Humans; Hypoxia; Persistent Vegetative State; Stroke; Zolpidem | 2018 |
Relationship between zolpidem use and stroke risk: a Taiwanese population-based case-control study.
Topics: Adult; Aged; Brain Ischemia; Case-Control Studies; Comorbidity; Female; Humans; Hypnotics and Sedati | 2013 |
Zolpidem induces paradoxical metabolic and vascular changes in a patient with PVS.
Topics: Adult; Female; GABA-A Receptor Agonists; Hemodynamics; Humans; Magnetic Resonance Imaging; Magnetic | 2013 |
In-flight emergency.
Topics: Aged; Aircraft; Confusion; Emergencies; Humans; Hypnotics and Sedatives; Male; Pyridines; Stroke; Zo | 2015 |
Enhanced phasic GABA inhibition during the repair phase of stroke: a novel therapeutic target.
Topics: Animals; Drug Delivery Systems; GABA-A Receptor Agonists; Male; Mice; Mice, Inbred C57BL; Neocortex; | 2016 |
GABA(A) alpha-1 subunit mediated desynchronization of elevated low frequency oscillations alleviates specific dysfunction in stroke--a case report.
Topics: Biological Clocks; Cognition Disorders; Evoked Potentials, Somatosensory; GABA Agonists; Humans; Mag | 2010 |
Transient improvement of poststroke apathy with zolpidem: a single-case, placebo-controlled double-blind study.
Topics: Adult; Apathy; Double-Blind Method; GABA-A Receptor Agonists; Humans; Male; Pyridines; Stroke; Surve | 2013 |
Transient improvement of aphasia with zolpidem.
Topics: Aphasia; Cerebrovascular Circulation; Female; GABA Agonists; Humans; Middle Aged; Pyridines; Stroke; | 2004 |
Effect of zolpidem on brain injury and diaschisis as detected by 99mTc HMPAO brain SPECT in humans.
Topics: Adult; Brain Injuries; Cerebellar Diseases; Cerebrovascular Circulation; Child, Preschool; Diabetes | 2004 |