Page last updated: 2024-11-05

zolpidem and Obesity

zolpidem has been researched along with Obesity in 5 studies

Zolpidem: An imidazopyridine derivative and short-acting GABA-A receptor agonist that is used for the treatment of INSOMNIA.
zolpidem : An imidazo[1,2-a]pyridine compound having a 4-tolyl group at the 2-position, an N,N-dimethylcarbamoylmethyl group at the 3-position and a methyl substituent at the 6-position.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"Lorcaserin is a selective and potent serotonin 2C receptor subtype (5-HT(2C)) agonist under development for the treatment of obesity."5.15Evaluation of the abuse potential of lorcaserin, a serotonin 2C (5-HT2C) receptor agonist, in recreational polydrug users. ( Anderson, CM; Bartlett, C; Schoedel, KA; Sellers, EM; Shazer, RL; Shram, MJ, 2011)
"Zolpidem (Ambien), a relatively new nonbenzodiazepine sedative-hypnotic, was involved in the death of a 39-year-old obese male who was being treated for depression and insomnia."3.69Zolpidem tissue concentrations in a multiple drug related death involving Ambien. ( Benson, PA; Macapagal, EC; Meeker, JE; Som, CW, 1995)
"16 patients with severe obstructive sleep apnea (apnea+ hypopnea index > 30/hr), on CPAP therapy for at least 6 months."2.72Effect of zolpidem on the efficacy of continuous positive airway pressure as treatment for obstructive sleep apnea. ( Berry, RB; Patel, PB, 2006)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buysse, DJ1
Pérez-Díaz, H1
Iranzo, A1
Santamaría, J1
Shram, MJ1
Schoedel, KA1
Bartlett, C1
Shazer, RL1
Anderson, CM1
Sellers, EM1
Berry, RB1
Patel, PB1
Meeker, JE1
Som, CW1
Macapagal, EC1
Benson, PA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double-Blind, Double-Dummy, Placebo- and Active-Controlled Crossover Study to Evaluate the Abuse Potential of Single Doses of Lorcaserin in Healthy Recreational Polydrug Users[NCT00828659]Phase 135 participants (Anticipated)Interventional2008-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for zolpidem and Obesity

ArticleYear
Evaluation of the abuse potential of lorcaserin, a serotonin 2C (5-HT2C) receptor agonist, in recreational polydrug users.
    Clinical pharmacology and therapeutics, 2011, Volume: 89, Issue:5

    Topics: Adolescent; Adult; Benzazepines; Cross-Over Studies; Double-Blind Method; Female; Humans; Illicit Dr

2011
Effect of zolpidem on the efficacy of continuous positive airway pressure as treatment for obstructive sleep apnea.
    Sleep, 2006, Volume: 29, Issue:8

    Topics: Adult; Arousal; Body Mass Index; Combined Modality Therapy; Continuous Positive Airway Pressure; Cro

2006

Other Studies

3 other studies available for zolpidem and Obesity

ArticleYear
Toward optimal health: diagnosis and management of disordered sleep in women: Dr. Daniel J Buysse interviewd by Jodi R. Godfrey.
    Journal of women's health (2002), 2009, Volume: 18, Issue:2

    Topics: Behavior Therapy; Cognition Disorders; Comorbidity; Female; Health Status; Humans; Hypnotics and Sed

2009
[Zolpidem-induced sleep-related behavioural disorders].
    Neurologia (Barcelona, Spain), 2010, Volume: 25, Issue:8

    Topics: Adult; Aged; Animals; Behavior; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Obesity;

2010
Zolpidem tissue concentrations in a multiple drug related death involving Ambien.
    Journal of analytical toxicology, 1995, Volume: 19, Issue:6

    Topics: Administration, Oral; Adult; Depression; Drug Overdose; Fatal Outcome; Gas Chromatography-Mass Spect

1995