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zolpidem and Long QT Syndrome

zolpidem has been researched along with Long QT Syndrome in 5 studies

Zolpidem: An imidazopyridine derivative and short-acting GABA-A receptor agonist that is used for the treatment of INSOMNIA.
zolpidem : An imidazo[1,2-a]pyridine compound having a 4-tolyl group at the 2-position, an N,N-dimethylcarbamoylmethyl group at the 3-position and a methyl substituent at the 6-position.

Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.

Research Excerpts

ExcerptRelevanceReference
"Zolpidem, a short-acting hypnotic drug prescribed to treat insomnia, has been clinically associated with acquired long QT syndrome (LQTS) and torsade de pointes (TdP) tachyarrhythmia."7.79Mechanisms of zolpidem-induced long QT syndrome: acute inhibition of recombinant hERG K(+) channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells. ( Becker, R; Deschenes, I; Ficker, E; Jehle, J; Katus, HA; Kisselbach, J; Schmidt, C; Schweizer, PA; Staudacher, I; Thomas, D; Wan, X; Wiedmann, F, 2013)
"Zolpidem, a short-acting hypnotic drug prescribed to treat insomnia, has been clinically associated with acquired long QT syndrome (LQTS) and torsade de pointes (TdP) tachyarrhythmia."3.79Mechanisms of zolpidem-induced long QT syndrome: acute inhibition of recombinant hERG K(+) channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells. ( Becker, R; Deschenes, I; Ficker, E; Jehle, J; Katus, HA; Kisselbach, J; Schmidt, C; Schweizer, PA; Staudacher, I; Thomas, D; Wan, X; Wiedmann, F, 2013)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Ahn, HJ1
Jeong, WJ1
Kim, KJ1
Kim, SC1
Kim, DW1
Chang, HJ1
Kang, CS1
Oh, SK1
Cho, SU1
Min, JH1
Cho, YC1
Park, JS1
Ryu, S1
You, YH1
Lee, JW1
Kim, MS1
Suarez, L1
Kolla, BP1
Hall-Flavin, D1
Mansukhani, MP1
Jehle, J1
Ficker, E1
Wan, X1
Deschenes, I1
Kisselbach, J1
Wiedmann, F1
Staudacher, I1
Schmidt, C1
Schweizer, PA1
Becker, R1
Katus, HA1
Thomas, D1
Letsas, KP1
Filippatos, GS1
Kounas, SP1
Efremidis, M1
Sideris, A1
Kardaras, F1
Somberg, J1
Molnar, J1

Other Studies

5 other studies available for zolpidem and Long QT Syndrome

ArticleYear
Serial plasma and urine measurements of a patient with acute intoxication of zolpidem and flunitrazepam resulting in QT prolongation and ventricular tachycardia.
    Clinical toxicology (Philadelphia, Pa.), 2020, Volume: 58, Issue:6

    Topics: Aged; Electrocardiography; Female; Flunitrazepam; Humans; Long QT Syndrome; Poisoning; Tachycardia,

2020
QTc Prolongation Secondary to Zolpidem Use.
    The primary care companion for CNS disorders, 2020, Mar-19, Volume: 22, Issue:2

    Topics: Aged; Female; Humans; Long QT Syndrome; Sleep Aids, Pharmaceutical; Sleep Initiation and Maintenance

2020
Mechanisms of zolpidem-induced long QT syndrome: acute inhibition of recombinant hERG K(+) channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells.
    British journal of pharmacology, 2013, Volume: 168, Issue:5

    Topics: Action Potentials; Animals; Cells, Cultured; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans;

2013
QT interval prolongation and Torsades de Pointes in a patient receiving zolpidem and amiodarone.
    Cardiology, 2006, Volume: 105, Issue:3

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Drug Interactions; Electric Countershock; Female; Heart Co

2006
Letter from Konstantinos P. Letsas et al. - invited editorial comment.
    Cardiology, 2006, Volume: 105, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Drug Interactions; Humans; Hypnotics and Sedatives; Long QT Synd

2006