Page last updated: 2024-11-05

zolpidem and Intertrochanteric Fractures

zolpidem has been researched along with Intertrochanteric Fractures in 11 studies

Zolpidem: An imidazopyridine derivative and short-acting GABA-A receptor agonist that is used for the treatment of INSOMNIA.
zolpidem : An imidazo[1,2-a]pyridine compound having a 4-tolyl group at the 2-position, an N,N-dimethylcarbamoylmethyl group at the 3-position and a methyl substituent at the 6-position.

Research Excerpts

ExcerptRelevanceReference
"The relative risk for hip fractures for suvorexant used in the model was based on data from pre-approval clinical trials."7.88Cost-effectiveness analysis of suvorexant for the treatment of Japanese elderly patients with chronic insomnia in a virtual cohort. ( Nakao, M; Nishimura, S, 2018)
"Zolpidem use was associated with a significant increased risk of hip fracture (adjusted odds ratio (AOR) 1."5.31Zolpidem use and hip fractures in older people. ( Avorn, J; Bohn, RL; Glynn, RJ; Mogun, H; Wang, PS, 2001)
"The relative risk for hip fractures for suvorexant used in the model was based on data from pre-approval clinical trials."3.88Cost-effectiveness analysis of suvorexant for the treatment of Japanese elderly patients with chronic insomnia in a virtual cohort. ( Nakao, M; Nishimura, S, 2018)
"Comparing zolpidem users with nonusers, there was considerable overestimation of an association with hip fractures if ADL scores (21."3.73Claims data studies of sedative-hypnotics and hip fractures in older people: exploring residual confounding using survey information. ( Schneeweiss, S; Wang, PS, 2005)
"For the treatment of insomnia in older adults, eszopiclone may present a safer alternative to zolpidem, in terms of fall-related injuries."1.43Nonbenzodiazepine Sedative Hypnotics and Risk of Fall-Related Injury. ( Albrecht, JS; Park, Y; Tom, SE; Wickwire, EM, 2016)
"Zolpidem use was associated with a significant increased risk of hip fracture (adjusted odds ratio (AOR) 1."1.31Zolpidem use and hip fractures in older people. ( Avorn, J; Bohn, RL; Glynn, RJ; Mogun, H; Wang, PS, 2001)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's6 (54.55)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Nagamine, T1
Donnelly, K1
Bracchi, R1
Hewitt, J1
Routledge, PA1
Carter, B1
Nishimura, S1
Nakao, M1
Bliwise, DL1
Lin, FY1
Chen, PC1
Liao, CH1
Hsieh, YW1
Sung, FC1
Tom, SE1
Wickwire, EM1
Park, Y1
Albrecht, JS1
Finkle, WD1
Der, JS1
Greenland, S1
Adams, JL1
Ridgeway, G1
Blaschke, T1
Wang, Z1
Dell, RM1
VanRiper, KB1
Schneeweiss, S1
Wang, PS3
Allain, H1
Bentué-Ferrer, D1
Polard, E1
Akwa, Y1
Patat, A1
Winkelmayer, WC1
Mehta, J1
Bohn, RL1
Glynn, RJ1
Mogun, H1
Avorn, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Web-based Cognitive Behavioral Treatment for Insomnia in Dementia Caregivers[NCT04632628]60 participants (Anticipated)Interventional2022-01-01Recruiting
SPIDER: A Structured Process Informed by Data, Evidence and Research - A Research and Quality Improvement Collaboration Supporting Practices in Improving Care for Complex Elderly Patients[NCT03689049]104 participants (Anticipated)Interventional2018-03-26Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for zolpidem and Intertrochanteric Fractures

ArticleYear
Benzodiazepines, Z-drugs and the risk of hip fracture: A systematic review and meta-analysis.
    PloS one, 2017, Volume: 12, Issue:4

    Topics: Benzodiazepines; Hip Fractures; Humans; Pyridines; Zolpidem

2017
Postural instability and consequent falls and hip fractures associated with use of hypnotics in the elderly: a comparative review.
    Drugs & aging, 2005, Volume: 22, Issue:9

    Topics: Accidental Falls; Acetamides; Aged; Aged, 80 and over; Azabicyclo Compounds; Benzodiazepines; Case-C

2005

Other Studies

9 other studies available for zolpidem and Intertrochanteric Fractures

ArticleYear
Long-term preoperative use of zolpidem is associated with postoperative delirium in elderly patients undergoing hip surgery.
    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2021, Volume: 21, Issue:4

    Topics: Aged; Delirium; Hip Fractures; Humans; Postoperative Complications; Risk Factors; Zolpidem

2021
Cost-effectiveness analysis of suvorexant for the treatment of Japanese elderly patients with chronic insomnia in a virtual cohort.
    Journal of medical economics, 2018, Volume: 21, Issue:7

    Topics: Aged; Aged, 80 and over; Azepines; Chronic Disease; Computer Simulation; Cost-Benefit Analysis; Fema

2018
Cataloging nocturia (circa 2014).
    Sleep, 2014, Apr-01, Volume: 37, Issue:4

    Topics: Behavior Therapy; Female; Hip Fractures; Humans; Male; Nocturia; Pyridines; Sleep Initiation and Mai

2014
Retrospective population cohort study on hip fracture risk associated with zolpidem medication.
    Sleep, 2014, Apr-01, Volume: 37, Issue:4

    Topics: Adolescent; Adult; Aged; Cohort Studies; Female; Hip Fractures; Humans; Hypnotics and Sedatives; Inc

2014
Nonbenzodiazepine Sedative Hypnotics and Risk of Fall-Related Injury.
    Sleep, 2016, 05-01, Volume: 39, Issue:5

    Topics: Accidental Falls; Acetamides; Aged; Aged, 80 and over; Brain Injuries, Traumatic; Cross-Over Studies

2016
Risk of fractures requiring hospitalization after an initial prescription for zolpidem, alprazolam, lorazepam, or diazepam in older adults.
    Journal of the American Geriatrics Society, 2011, Volume: 59, Issue:10

    Topics: Aged; Aged, 80 and over; Alprazolam; Causality; Cohort Studies; Cross-Sectional Studies; Diazepam; F

2011
Claims data studies of sedative-hypnotics and hip fractures in older people: exploring residual confounding using survey information.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:6

    Topics: Activities of Daily Living; Aged; Benzodiazepines; Confounding Factors, Epidemiologic; Cross-Section

2005
Benzodiazepine use and mortality of incident dialysis patients in the United States.
    Kidney international, 2007, Volume: 72, Issue:11

    Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Cohort Studies; Depression; Female; Foll

2007
Zolpidem use and hip fractures in older people.
    Journal of the American Geriatrics Society, 2001, Volume: 49, Issue:12

    Topics: Aged; Aged, 80 and over; Aging; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Benzot

2001