Page last updated: 2024-11-05

zolpidem and Idiopathic Parkinson Disease

zolpidem has been researched along with Idiopathic Parkinson Disease in 12 studies

Zolpidem: An imidazopyridine derivative and short-acting GABA-A receptor agonist that is used for the treatment of INSOMNIA.
zolpidem : An imidazo[1,2-a]pyridine compound having a 4-tolyl group at the 2-position, an N,N-dimethylcarbamoylmethyl group at the 3-position and a methyl substituent at the 6-position.

Research Excerpts

ExcerptRelevanceReference
"Zolpidem use might unmask preclinical Parkinson's disease, especially in patients with depression."3.81Risk of Parkinson's disease following zolpidem use: a retrospective, population-based cohort study. ( Huang, HC; Kao, CH; Lin, KH; Lu, MK; Muo, CH; Sung, FC; Tsai, CH, 2015)
"To illustrate the beneficial effect of zolpidem on the neuropsychiatric and motor symptoms in a patient with Parkinson disease (PD) after bilateral subthalamic nucleus deep brain stimulation."3.78Zolpidem improves neuropsychiatric symptoms and motor dysfunction in a patient with Parkinson's disease after deep brain stimulation. ( Chiou, SM; Hsu, YT; Huang, HY; Kao, CH; Tsai, CH; Tsai, MC; Wu, YC, 2012)
"Zolpidem is an imidazopyridine agonist with a high affinity on the benzodiazepine site of GABA(A) receptors containing alpha 1 subunit."1.34Zolpidem modulates GABA(A) receptor function in subthalamic nucleus. ( Chen, L; Fung, KS; Xie, JX; Yung, WH, 2007)
"Patients with Parkinson's disease have been known to have sleep disturbances of various types."1.33[A hypnotic drug for sleep disturbances in patients with Parkinson's disease]. ( Abe, K; Hikita, T; Sakoda, S, 2005)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's5 (41.67)29.6817
2010's5 (41.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yang, YW1
Hsieh, TF1
Yu, CH1
Huang, YS1
Lee, CC1
Tsai, TH1
Hall, SD1
Prokic, EJ1
McAllister, CJ1
Ronnqvist, KC1
Williams, AC1
Yamawaki, N1
Witton, C1
Woodhall, GL1
Stanford, IM1
Huang, HC1
Tsai, CH2
Muo, CH1
Lin, KH1
Lu, MK1
Sung, FC1
Kao, CH2
Kojović, M1
Gregorič Kramberger, M1
Huang, HY1
Hsu, YT1
Wu, YC1
Chiou, SM1
Tsai, MC1
Abe, K1
Hikita, T1
Sakoda, S1
Chen, L1
Xie, JX1
Fung, KS1
Yung, WH1
Chen, YY1
Sy, HN1
Wu, SL1
Daniele, A1
Albanese, A1
Gainotti, G1
Gregori, B1
Bartolomeo, P1
Lavoisy, J1
Marsac, J1
Růzicka, E1
Roth, J1
Jech, R1
Busek, P1
Evidente, VG1

Trials

1 trial available for zolpidem and Idiopathic Parkinson Disease

ArticleYear
Zolpidem in Parkinson's disease.
    Lancet (London, England), 1997, Apr-26, Volume: 349, Issue:9060

    Topics: Antiparkinson Agents; Cross-Over Studies; Double-Blind Method; Female; Globus Pallidus; Humans; Hypn

1997

Other Studies

11 other studies available for zolpidem and Idiopathic Parkinson Disease

ArticleYear
Zolpidem and the risk of Parkinson's disease: a nationwide population-based study.
    Journal of psychiatric research, 2014, Volume: 58

    Topics: Adult; Analysis of Variance; Cohort Studies; Community Health Planning; Female; Humans; Hypnotics an

2014
GABA-mediated changes in inter-hemispheric beta frequency activity in early-stage Parkinson's disease.
    Neuroscience, 2014, Dec-05, Volume: 281

    Topics: Aged; Beta Rhythm; Electroencephalography Phase Synchronization; Female; GABA-A Receptor Agonists; H

2014
Risk of Parkinson's disease following zolpidem use: a retrospective, population-based cohort study.
    The Journal of clinical psychiatry, 2015, Volume: 76, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzodiazepines; Comorbidity; Depression; Female; Humans

2015
Zolpidem withdrawal status dystonicus in the patient with advanced Parkinson's disease.
    Parkinsonism & related disorders, 2015, Volume: 21, Issue:6

    Topics: Dystonia; GABA-A Receptor Agonists; Humans; Male; Middle Aged; Parkinson Disease; Pyridines; Severit

2015
Zolpidem improves neuropsychiatric symptoms and motor dysfunction in a patient with Parkinson's disease after deep brain stimulation.
    Acta neurologica Taiwanica, 2012, Volume: 21, Issue:2

    Topics: Confusion; Deep Brain Stimulation; Female; Fluorodeoxyglucose F18; Humans; Hypnotics and Sedatives;

2012
[A hypnotic drug for sleep disturbances in patients with Parkinson's disease].
    No to shinkei = Brain and nerve, 2005, Volume: 57, Issue:4

    Topics: Adult; Aged; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Parkinson Disease; Pyridine

2005
Zolpidem modulates GABA(A) receptor function in subthalamic nucleus.
    Neuroscience research, 2007, Volume: 58, Issue:1

    Topics: Animals; Flumazenil; GABA Agonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antag

2007
Zolpidem improves akinesia, dystonia and dyskinesia in advanced Parkinson's disease.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2008, Volume: 15, Issue:8

    Topics: Dyskinesias; Dystonia; Humans; Hypnotics and Sedatives; Male; Middle Aged; Parkinson Disease; Pyridi

2008
Zolpidem in Parkinson's disease.
    Lancet (London, England), 1997, Jul-05, Volume: 350, Issue:9070

    Topics: Antiparkinson Agents; Humans; Hypnotics and Sedatives; Parkinson Disease; Pyridines; Zolpidem

1997
Subhypnotic doses of zolpidem oppose dopaminergic-induced dyskinesia in Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2000, Volume: 15, Issue:4

    Topics: Dopamine Agents; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; GABA Agonists;

2000
Zolpidem improves dystonia in "Lubag" or X-linked dystonia-parkinsonism syndrome.
    Neurology, 2002, Feb-26, Volume: 58, Issue:4

    Topics: Adult; Dystonic Disorders; Genetic Linkage; Humans; Hypnotics and Sedatives; Male; Parkinson Disease

2002