Page last updated: 2024-11-05

zolpidem and Hepatic Insufficiency

zolpidem has been researched along with Hepatic Insufficiency in 1 studies

Zolpidem: An imidazopyridine derivative and short-acting GABA-A receptor agonist that is used for the treatment of INSOMNIA.
zolpidem : An imidazo[1,2-a]pyridine compound having a 4-tolyl group at the 2-position, an N,N-dimethylcarbamoylmethyl group at the 3-position and a methyl substituent at the 6-position.

Hepatic Insufficiency: Conditions in which the LIVER functions fall below the normal ranges. Severe hepatic insufficiency may cause LIVER FAILURE or DEATH. Treatment may include LIVER TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
"This paper addresses the pharmacokinetic properties of eszopiclone and the extent to which the longer half-life of eszopiclone compared to other commonly used hypnotics (immediate-release zolpidem, modified-release zolpidem, triazolam, zaleplon) may translate into either improved efficacy in enhancing sleep maintenance, or increased probability of residual sedative or performance-impairing effects."1.38Pharmacokinetic evaluation of eszopiclone: clinical and therapeutic implications. ( Greenblatt, DJ; Zammit, GK, 2012)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Greenblatt, DJ1
Zammit, GK1

Other Studies

1 other study available for zolpidem and Hepatic Insufficiency

ArticleYear
Pharmacokinetic evaluation of eszopiclone: clinical and therapeutic implications.
    Expert opinion on drug metabolism & toxicology, 2012, Volume: 8, Issue:12

    Topics: Acetamides; Adult; Aged; Azabicyclo Compounds; Clinical Trials as Topic; Cytochrome P-450 CYP3A; Cyt

2012