zolpidem has been researched along with Drug Overdose in 26 studies
Zolpidem: An imidazopyridine derivative and short-acting GABA-A receptor agonist that is used for the treatment of INSOMNIA.
zolpidem : An imidazo[1,2-a]pyridine compound having a 4-tolyl group at the 2-position, an N,N-dimethylcarbamoylmethyl group at the 3-position and a methyl substituent at the 6-position.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe the case of a 73-year-old woman who suffered from a prolonged coma after acute self poisoning with bromazepam (serum concentration of 2,000 ng/ml at admission, 2 - 10 hours after ingestion of up to 180 mg) and zolpidem (900 ng/ml at admission)." | 7.76 | Protracted deep coma after bromazepam poisoning. ( Capdevila, X; Harry, P; Lakhal, K; Mathieu-Daude, JC; Pallancher, S, 2010) |
| " Retrospectively, both subjects suffered from psychiatric disorders and in case 2, the subject was treated for depression with doxepin." | 3.81 | Sleep self-intoxication and sleep driving as rare zolpidem-induced complex behaviour. ( Paulke, A; Toennes, SW; Wunder, C, 2015) |
| " Predictors were calculated in 6-month intervals and exactly 6 months before a drug overdose: opioid use (mean daily morphine-equivalent dose), benzodiazepine use (days' supply), antidepressant use (days' supply), zolpidem use (days' supply), mental health disorders (depression, anxiety/PTSD, psychosis), pain-related conditions, and substance use disorders (alcohol, other drug)." | 3.81 | Drug Overdose in a Retrospective Cohort with Non-Cancer Pain Treated with Opioids, Antidepressants, and/or Sedative-Hypnotics: Interactions with Mental Health Disorders. ( Liang, Y; Turner, BJ, 2015) |
| "We describe the case of a 73-year-old woman who suffered from a prolonged coma after acute self poisoning with bromazepam (serum concentration of 2,000 ng/ml at admission, 2 - 10 hours after ingestion of up to 180 mg) and zolpidem (900 ng/ml at admission)." | 3.76 | Protracted deep coma after bromazepam poisoning. ( Capdevila, X; Harry, P; Lakhal, K; Mathieu-Daude, JC; Pallancher, S, 2010) |
| "Zolpidem (Ambien), a relatively new nonbenzodiazepine sedative-hypnotic, was involved in the death of a 39-year-old obese male who was being treated for depression and insomnia." | 3.69 | Zolpidem tissue concentrations in a multiple drug related death involving Ambien. ( Benson, PA; Macapagal, EC; Meeker, JE; Som, CW, 1995) |
| "Flumazenil was not given in 55 cases." | 2.68 | Emergency department use of flumazenil prior to poison center consultation. ( Aks, S; Burda, T; Fischbein, C; Leikin, JB; Woods, K, 1997) |
| "Flumazenil has been reported to reverse sedation from all three Z-drugs." | 2.49 | The clinical and forensic toxicology of Z-drugs. ( Gunja, N, 2013) |
| "Flumazenil has been reported to reverse the CNS effects of zolpidem." | 1.39 | Pediatric zolpidem ingestion demonstrating zero-order kinetics treated with flumazenil. ( Carstairs, SD; Negus, E; Thornton, SL, 2013) |
| "Zolpidem was not present." | 1.35 | A fatal case of benzodiazepine withdrawal. ( Lann, MA; Molina, DK, 2009) |
| "A ventricular fibrillation was treated with external cardiac massage." | 1.34 | [Treatment of hydroxychloroquine poisoning with extracorporeal circulation]. ( Blin, D; Derderian, F; Durand, M; Gonthier, YT; Mongenot, F, 2007) |
| "Delirium is characterized by disturbances of consciousness, attention, cognition, and perception and is the most common reason for acute cognitive dysfunction in hospitalized elderly patients." | 1.33 | Medication sleuth: an important role for pharmacists in determining the etiology of delirium. ( Collins, RJ, 2006) |
| "Zolpidem (Ambien) is an imidazopyridine hypnotic recently introduced in the USA." | 1.29 | Acute overdose of zolpidem. ( Janssen, JK; Rafizadeh, V; Rozin, L; Wahba, WW; Winek, CL, 1996) |
| "Flumazenil (Anexate) was an effective antidote in mono- and combined intoxications involving zolpidem." | 1.29 | [Acute overdose of Zolpidem (Stilnox)]. ( Meier-Abt, PJ; Radovanovic, D; Wyss, PA, 1996) |
| " The methods used for pharmacokinetic and drug metabolism studies are based on column-switching high-performance liquid chromatography; they do not require any sample manipulation because the plasma or diluted urine is injected into a pre-column where clean-up and preconcentration take place." | 1.28 | Determination of zolpidem, a new sleep-inducing agent, and its metabolites in biological fluids: pharmacokinetics, drug metabolism and overdosing investigations in humans. ( Ascalone, V; Flaminio, L; Guinebault, P; Morselli, PL; Thénot, JP, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (26.92) | 18.2507 |
| 2000's | 6 (23.08) | 29.6817 |
| 2010's | 12 (46.15) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Szmulewicz, A | 1 |
| Bateman, BT | 1 |
| Levin, R | 1 |
| Huybrechts, KF | 1 |
| Gunja, N | 1 |
| Bach, AG | 1 |
| Eisenkrämer, A | 1 |
| Surov, A | 1 |
| Siekmann, H | 1 |
| Chapla, N | 1 |
| Gallucci, G | 1 |
| Trimzi, I | 1 |
| Meier, BR | 1 |
| Thornton, SL | 1 |
| Negus, E | 1 |
| Carstairs, SD | 1 |
| Millman, D | 1 |
| Paulke, A | 1 |
| Wunder, C | 1 |
| Toennes, SW | 1 |
| Turner, BJ | 1 |
| Liang, Y | 1 |
| Chou, S | 1 |
| Ayabe, S | 1 |
| Sekine, N | 1 |
| Zhang, YZ | 1 |
| He, HY | 1 |
| She, CM | 1 |
| Lian, J | 1 |
| Chang, LC | 1 |
| Hung, SC | 1 |
| Yang, CS | 1 |
| Lann, MA | 1 |
| Molina, DK | 1 |
| Lakhal, K | 1 |
| Pallancher, S | 1 |
| Mathieu-Daude, JC | 1 |
| Harry, P | 1 |
| Capdevila, X | 1 |
| Manfredi, G | 1 |
| Kotzalidis, GD | 1 |
| Lazanio, S | 1 |
| Savoja, V | 1 |
| Talamo, A | 1 |
| Koukopoulos, AE | 1 |
| Sani, G | 1 |
| Trevisi, M | 1 |
| Tatarelli, R | 1 |
| Girardi, P | 1 |
| Zosel, A | 1 |
| Osterberg, EC | 1 |
| Mycyk, MB | 1 |
| Langford, NJ | 1 |
| Martin, U | 1 |
| Ruprah, M | 1 |
| Ferner, RE | 1 |
| Collins, RJ | 1 |
| Mongenot, F | 1 |
| Gonthier, YT | 1 |
| Derderian, F | 1 |
| Durand, M | 1 |
| Blin, D | 1 |
| Winek, CL | 1 |
| Wahba, WW | 1 |
| Janssen, JK | 1 |
| Rozin, L | 1 |
| Rafizadeh, V | 1 |
| Wyss, PA | 1 |
| Radovanovic, D | 1 |
| Meier-Abt, PJ | 1 |
| Meeker, JE | 1 |
| Som, CW | 1 |
| Macapagal, EC | 1 |
| Benson, PA | 1 |
| Burda, T | 1 |
| Leikin, JB | 1 |
| Fischbein, C | 1 |
| Woods, K | 1 |
| Aks, S | 1 |
| Keller, T | 1 |
| Schneider, A | 1 |
| Tutsch-Bauer, E | 1 |
| Musshoff, F | 1 |
| Schmidt, P | 1 |
| Madea, B | 1 |
| Hamad, A | 1 |
| Sharma, N | 1 |
| Ascalone, V | 1 |
| Flaminio, L | 1 |
| Guinebault, P | 1 |
| Thénot, JP | 1 |
| Morselli, PL | 1 |
3 reviews available for zolpidem and Drug Overdose
| Article | Year |
|---|---|
The clinical and forensic toxicology of Z-drugs.
Topics: Acetamides; Azabicyclo Compounds; Coma; Drug Overdose; Flumazenil; GABA Modulators; GABA-A Receptor | 2013 |
Myocardial Injury without Electrocardiographic Changes after a Suicide Attempt by an Overdose of Glimepiride and Zolpidem: A Case Report and Literature Review.
Topics: Adult; Biomarkers; Creatine Kinase, MB Form; Drug Overdose; GABA-A Receptor Agonists; Heart Injuries | 2015 |
[Research Progress on Forensic Toxicology of Z-drugs].
Topics: Acetamides; Azabicyclo Compounds; Drug Overdose; Forensic Medicine; Forensic Toxicology; Humans; Hyp | 2015 |
1 trial available for zolpidem and Drug Overdose
| Article | Year |
|---|---|
Emergency department use of flumazenil prior to poison center consultation.
Topics: Antidotes; Benzodiazepines; Contraindications; Drug Overdose; Flumazenil; Humans; Hypnotics and Seda | 1997 |
22 other studies available for zolpidem and Drug Overdose
| Article | Year |
|---|---|
The Risk of Overdose With Concomitant Use of Z-Drugs and Prescription Opioids: A Population-Based Cohort Study.
Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Azabicyclo Compounds; Dr | 2021 |
[51-year-old-man found somnolent on the street].
Topics: Diagnosis, Differential; Drug Overdose; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pyridine | 2013 |
Addicted to sleep: A case of Ambien abuse.
Topics: Drug Overdose; Female; Humans; Hypnotics and Sedatives; Middle Aged; Pyridines; Substance-Related Di | 2013 |
Pediatric zolpidem ingestion demonstrating zero-order kinetics treated with flumazenil.
Topics: Antidotes; Central Nervous System Depressants; Child; Coma; Down Syndrome; Drug Overdose; Emergencie | 2013 |
Psychiatric hospitalization story.
Topics: Attitude of Health Personnel; Drug Overdose; Hospitalization; Hospitals, Psychiatric; Humans; Incide | 2011 |
Sleep self-intoxication and sleep driving as rare zolpidem-induced complex behaviour.
Topics: Adult; Amnesia; Antidepressive Agents, Tricyclic; Automobile Driving; Depression; Doxepin; Drug Over | 2015 |
Drug Overdose in a Retrospective Cohort with Non-Cancer Pain Treated with Opioids, Antidepressants, and/or Sedative-Hypnotics: Interactions with Mental Health Disorders.
Topics: Adolescent; Adult; Analgesics, Opioid; Antidepressive Agents; Benzodiazepines; Drug Overdose; Female | 2015 |
The case. A suicidal woman with delayed high anion gap metabolic acidosis.
Topics: Acidosis; Diabetes Mellitus, Type 2; Drug Overdose; Female; Humans; Metformin; Middle Aged; Pyridine | 2009 |
A fatal case of benzodiazepine withdrawal.
Topics: Adult; Alprazolam; Anti-Anxiety Agents; Diagnosis, Differential; Diagnostic Errors; Drug Overdose; F | 2009 |
Protracted deep coma after bromazepam poisoning.
Topics: Aged; Anti-Anxiety Agents; Antidotes; Bromazepam; Charcoal; Coma; Drug Overdose; Female; Half-Life; | 2010 |
Command hallucinations with self-stabbing associated with zolpidem overdose.
Topics: Adult; Bipolar Disorder; Drug Overdose; Hallucinations; Humans; Hypnotics and Sedatives; Male; Pyrid | 2010 |
Zolpidem misuse with other medications or alcohol frequently results in intensive care unit admission.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Child; Child, Preschool; Drug Interact | 2011 |
Alternative venlafaxine kinetics in overdose.
Topics: Adult; Antidepressive Agents, Second-Generation; Area Under Curve; Cyclohexanols; Cytochrome P-450 C | 2002 |
Medication sleuth: an important role for pharmacists in determining the etiology of delirium.
Topics: Aged; Delirium; Diagnosis, Differential; Drug Overdose; Female; Hospitalization; Humans; Hypnotics a | 2006 |
[Treatment of hydroxychloroquine poisoning with extracorporeal circulation].
Topics: Adult; Antidotes; Bromazepam; Charcoal; Coma; Combined Modality Therapy; Diazepam; Drug Overdose; Ep | 2007 |
Acute overdose of zolpidem.
Topics: Aged; Drug Overdose; Fatal Outcome; Female; Humans; Hypnotics and Sedatives; Pyridines; Zolpidem | 1996 |
[Acute overdose of Zolpidem (Stilnox)].
Topics: Adolescent; Adult; Aged; Antidotes; Coma; Drug Overdose; Female; Flumazenil; Humans; Hypnotics and S | 1996 |
Zolpidem tissue concentrations in a multiple drug related death involving Ambien.
Topics: Administration, Oral; Adult; Depression; Drug Overdose; Fatal Outcome; Gas Chromatography-Mass Spect | 1995 |
GC/MS determination of zolpidem in postmortem specimens in a voluntary intoxication.
Topics: Alcoholism; Autopsy; Drug Overdose; Fatal Outcome; Female; Gas Chromatography-Mass Spectrometry; Gas | 1999 |
Fatality caused by a combined trimipramine-citalopram intoxication.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Citalopram; Depression; | 1999 |
Acute zolpidem overdose leading to coma and respiratory failure.
Topics: Adult; Coma; Drug Overdose; Humans; Hypnotics and Sedatives; Male; Pyridines; Respiratory Insufficie | 2001 |
Determination of zolpidem, a new sleep-inducing agent, and its metabolites in biological fluids: pharmacokinetics, drug metabolism and overdosing investigations in humans.
Topics: Chromatography, High Pressure Liquid; Drug Overdose; Humans; Hypnotics and Sedatives; Pyridines; Rep | 1992 |