zolpidem has been researched along with Disorders of Excessive Somnolence in 9 studies
Zolpidem: An imidazopyridine derivative and short-acting GABA-A receptor agonist that is used for the treatment of INSOMNIA.
zolpidem : An imidazo[1,2-a]pyridine compound having a 4-tolyl group at the 2-position, an N,N-dimethylcarbamoylmethyl group at the 3-position and a methyl substituent at the 6-position.
Disorders of Excessive Somnolence: Disorders characterized by hypersomnolence during normal waking hours that may impair cognitive functioning. Subtypes include primary hypersomnia disorders (e.g., IDIOPATHIC HYPERSOMNOLENCE; NARCOLEPSY; and KLEINE-LEVIN SYNDROME) and secondary hypersomnia disorders where excessive somnolence can be attributed to a known cause (e.g., drug affect, MENTAL DISORDERS, and SLEEP APNEA SYNDROME). (From J Neurol Sci 1998 Jan 8;153(2):192-202; Thorpy, Principles and Practice of Sleep Medicine, 2nd ed, p320)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this study was to investigate the efficacy of zolpidem for improving post-operative sleep quality among patients with infective endocarditis (IE) and to identify the potential risk factors for impaired sleep quality at 6 months after surgery." | 8.12 | Zolpidem improves patients' sleep quality after surgical treatment for infective endocarditis: a prospective observational study. ( Hu, X; Huang, D; Huang, F; Huang, X; Jia, F; Li, X; Liao, H; Lin, C; Lu, F; Wei, W; Yu, Z, 2022) |
| "Sodium oxybate (SXB) is approved for cataplexy and excessive daytime sleepiness in narcolepsy." | 5.15 | A 2-week, polysomnographic, safety study of sodium oxybate in obstructive sleep apnea syndrome. ( Feldman, N; George, CF; Grzeschik, SM; Inhaber, N; Lai, C; Steininger, TL; Zheng, Y, 2011) |
| "To assess the effects of zolpidem and zaleplon on nocturnal sleep and breathing patterns at altitude, as well as on daytime attention, fatigue, and sleepiness." | 5.12 | Zaleplon and zolpidem objectively alleviate sleep disturbances in mountaineers at a 3,613 meter altitude. ( Batéjat, D; Beaumont, M; Jouanin, JC; Léger, D; Philippe, M; Piérard, C; Savourey, G; Van Beers, P, 2007) |
| " Pitolisant, a novel histamine-3 receptor antagonist/inverse agonist, gained approval for the treatment of excessive daytime sleepiness in adults with narcolepsy as well as obstructive sleep apnea." | 5.05 | New pharmacologic agents for insomnia and hypersomnia. ( Earl, DC; Van Tyle, KM, 2020) |
| "The objective of this study was to investigate the efficacy of zolpidem for improving post-operative sleep quality among patients with infective endocarditis (IE) and to identify the potential risk factors for impaired sleep quality at 6 months after surgery." | 4.12 | Zolpidem improves patients' sleep quality after surgical treatment for infective endocarditis: a prospective observational study. ( Hu, X; Huang, D; Huang, F; Huang, X; Jia, F; Li, X; Liao, H; Lin, C; Lu, F; Wei, W; Yu, Z, 2022) |
| "Sleep quality, sleepiness and symptoms of acute mountain sickness were assessed by questionnaires." | 2.87 | The effect of zolpidem on cognitive function and postural control at high altitude. ( Baillieul, S; Banco, P; Botrè, F; Bouzat, P; Casini, L; Davranche, K; De la Torre, X; Manhes, P; Mazzarino, M; Robach, P; Séchaud, G; Verges, S, 2018) |
| "Triazolam was associated with longer total sleep time and increased Stage 2 sleep." | 1.36 | Retrograde effects of triazolam and zolpidem on sleep-dependent motor learning in humans. ( Kehne, JH; Malison, RT; Morgan, PT; Sprenger, KJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Earl, DC | 1 |
| Van Tyle, KM | 1 |
| Hu, X | 1 |
| Huang, D | 1 |
| Lin, C | 1 |
| Li, X | 1 |
| Lu, F | 1 |
| Wei, W | 1 |
| Yu, Z | 1 |
| Liao, H | 1 |
| Huang, F | 1 |
| Huang, X | 1 |
| Jia, F | 1 |
| Bouzat, P | 1 |
| Séchaud, G | 1 |
| Banco, P | 1 |
| Davranche, K | 1 |
| Casini, L | 1 |
| Baillieul, S | 1 |
| Manhes, P | 1 |
| Botrè, F | 1 |
| Mazzarino, M | 1 |
| De la Torre, X | 1 |
| Robach, P | 1 |
| Verges, S | 1 |
| Mednick, SC | 1 |
| McDevitt, EA | 1 |
| Walsh, JK | 1 |
| Wamsley, E | 1 |
| Paulus, M | 1 |
| Kanady, JC | 1 |
| Drummond, SP | 1 |
| Morgan, PT | 1 |
| Kehne, JH | 1 |
| Sprenger, KJ | 1 |
| Malison, RT | 1 |
| George, CF | 1 |
| Feldman, N | 1 |
| Zheng, Y | 1 |
| Steininger, TL | 1 |
| Grzeschik, SM | 1 |
| Lai, C | 1 |
| Inhaber, N | 1 |
| Dopp, JM | 1 |
| Morgan, BJ | 1 |
| Steinig, J | 1 |
| Klösch, G | 1 |
| Sauter, C | 1 |
| Zeitlhofer, J | 1 |
| Happe, S | 1 |
| Beaumont, M | 1 |
| Batéjat, D | 1 |
| Piérard, C | 1 |
| Van Beers, P | 1 |
| Philippe, M | 1 |
| Léger, D | 1 |
| Savourey, G | 1 |
| Jouanin, JC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of High-altitude Sleep Disturbance: A Double-blind Comparison of Temazepam Versus Acetazolamide.[NCT01519544] | 34 participants (Actual) | Interventional | 2012-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for zolpidem and Disorders of Excessive Somnolence
| Article | Year |
|---|---|
New pharmacologic agents for insomnia and hypersomnia.
Topics: Azepines; Carbamates; Dementia; Disorders of Excessive Somnolence; GABA-A Receptor Agonists; Humans; | 2020 |
Pharmacologic approaches for the management of symptoms and cardiovascular consequences of obstructive sleep apnea in adults.
Topics: Benzhydryl Compounds; Cardiovascular Diseases; Central Nervous System Stimulants; Combined Modality | 2010 |
4 trials available for zolpidem and Disorders of Excessive Somnolence
| Article | Year |
|---|---|
The effect of zolpidem on cognitive function and postural control at high altitude.
Topics: Adult; Altitude; Altitude Sickness; Cognition; Cross-Over Studies; Disorders of Excessive Somnolence | 2018 |
The critical role of sleep spindles in hippocampal-dependent memory: a pharmacology study.
Topics: Adolescent; Adult; Analysis of Variance; Brain Waves; Cross-Over Studies; Disorders of Excessive Som | 2013 |
A 2-week, polysomnographic, safety study of sodium oxybate in obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Benzhydryl Compounds; Central Nervous System Stimulants; Combined Moda | 2011 |
Zaleplon and zolpidem objectively alleviate sleep disturbances in mountaineers at a 3,613 meter altitude.
Topics: Acetamides; Altitude; Attention; Cross-Over Studies; Disorders of Excessive Somnolence; Double-Blind | 2007 |
3 other studies available for zolpidem and Disorders of Excessive Somnolence
| Article | Year |
|---|---|
Zolpidem improves patients' sleep quality after surgical treatment for infective endocarditis: a prospective observational study.
Topics: Disorders of Excessive Somnolence; Endocarditis; Humans; Sleep; Sleep Initiation and Maintenance Dis | 2022 |
Retrograde effects of triazolam and zolpidem on sleep-dependent motor learning in humans.
Topics: Adult; Arousal; Cognition Disorders; Disorders of Excessive Somnolence; Dose-Response Relationship, | 2010 |
Actigraphy in irregular sleep-wake rhythm.
Topics: Adult; Behavior Therapy; Combined Modality Therapy; Disorders of Excessive Somnolence; Female; Human | 2007 |