Page last updated: 2024-11-05

zolpidem and Behavior Disorders

zolpidem has been researched along with Behavior Disorders in 12 studies

Zolpidem: An imidazopyridine derivative and short-acting GABA-A receptor agonist that is used for the treatment of INSOMNIA.
zolpidem : An imidazo[1,2-a]pyridine compound having a 4-tolyl group at the 2-position, an N,N-dimethylcarbamoylmethyl group at the 3-position and a methyl substituent at the 6-position.

Research Excerpts

ExcerptRelevanceReference
" Predictors were calculated in 6-month intervals and exactly 6 months before a drug overdose: opioid use (mean daily morphine-equivalent dose), benzodiazepine use (days' supply), antidepressant use (days' supply), zolpidem use (days' supply), mental health disorders (depression, anxiety/PTSD, psychosis), pain-related conditions, and substance use disorders (alcohol, other drug)."3.81Drug Overdose in a Retrospective Cohort with Non-Cancer Pain Treated with Opioids, Antidepressants, and/or Sedative-Hypnotics: Interactions with Mental Health Disorders. ( Liang, Y; Turner, BJ, 2015)
"Chronic insomnia is a prevalent disorder associated with significant psychosocial, health, and economic impacts."2.82Sequential psychological and pharmacological therapies for comorbid and primary insomnia: study protocol for a randomized controlled trial. ( Beaulieu-Bonneau, S; Buysse, DJ; Edinger, JD; Ivers, H; Krystal, AD; Morin, CM, 2016)
"Insomnia is a cardinal symptom for many psychiatric disorders, especially depressive disorders."2.41A psychiatric perspective on insomnia. ( McCall, WV, 2001)
"In particular, patients with chronic insomnia have higher rates of psychiatric and medical illnesses, and insomnia is an important risk factor in the development of depression."2.41Consequences of insomnia and its therapies. ( Benca, RM, 2001)
"Comorbid psychiatric illness was diagnosed in 67 patients (39."1.46Benzodiazepine and "Z-Drug" Dependence: Data From a Tertiary Care Center. ( Benegal, V; Bokka, S; Chand, P; Kandasamy, A; Murthy, P; Shukla, L; Shukla, T, 2017)
"Zolpidem is a widely used ultrashort-acting non-benzodiazepine in clinical practice; compared with benzodiazepines, it does not have side effects such as daytime hangover, rebound insomnia, and development of tolerance."1.42[An Autopsy Case of Abnormal Behaviour Induced by Zolpidem]. ( Ikeda, N; Kudo, K; Sameshima, N; Sato, K; Tsuji, A; Usumoto, Y, 2015)
"Zolpidem is a short acting hypnotic drug belonging to imidazopyridine family."1.34Seizure following sudden zolpidem withdrawal. ( Cubała, WJ; Landowski, J, 2007)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (25.00)29.6817
2010's9 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vanda, D1
Zajdel, P1
Soural, M1
Schepis, TS1
Turner, BJ1
Liang, Y1
Motamedi, GK1
Wheeler, MG1
Usumoto, Y1
Kudo, K1
Sameshima, N1
Sato, K1
Tsuji, A1
Ikeda, N1
Morin, CM1
Edinger, JD1
Krystal, AD1
Buysse, DJ1
Beaulieu-Bonneau, S1
Ivers, H1
Shukla, L1
Bokka, S1
Shukla, T1
Kandasamy, A1
Chand, P1
Benegal, V1
Murthy, P1
Poceta, JS1
Jang, M1
Chang, H1
Yang, W1
Choi, H1
Kim, E1
Yu, BH1
Oh, Y1
Chung, H1
Cubała, WJ1
Landowski, J1
McCall, WV1
Benca, RM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Sequenced Therapies for Comorbid and Primary Insomnias[NCT01651442]211 participants (Actual)Interventional2012-08-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Percent of Participants Who Met Remission as Measured by the Insomnia Severity Index

The Insomnia Severity Index (ISI) is a self-report questionnaire assessing the nature, severity, and impact of insomnia. Remission is determined to be a score less-than 8. (NCT01651442)
Timeframe: 6 weeks, 12 weeks, 3 months, 6 months, 9 months & 12 months

Interventionpercent remitted (Number)
Non-drug Sleep Therapy 140.00
Sleep Medication 134.94
Sleep Medication 1 Plus Non-drug Sleep Therapy 137.04
Sleep Medication 1 Plus Sleep Medication 248.15
Non-drug Sleep Therapy 1 Plus Non-drug Sleep Therapy 144.44
Non-drug Sleep Therapy 1 Plus Sleep Medication 155.56

Reviews

3 reviews available for zolpidem and Behavior Disorders

ArticleYear
Imidazopyridine-based selective and multifunctional ligands of biological targets associated with psychiatric and neurodegenerative diseases.
    European journal of medicinal chemistry, 2019, Nov-01, Volume: 181

    Topics: Animals; Clinical Trials as Topic; Drug Design; Humans; Imidazoles; Ligands; Mental Disorders; Molec

2019
A psychiatric perspective on insomnia.
    The Journal of clinical psychiatry, 2001, Volume: 62 Suppl 10

    Topics: Acetamides; Benzodiazepines; Comorbidity; Depressive Disorder; Diagnosis, Differential; GABA-A Recep

2001
Consequences of insomnia and its therapies.
    The Journal of clinical psychiatry, 2001, Volume: 62 Suppl 10

    Topics: Acetamides; Circadian Rhythm; Comorbidity; Half-Life; Health Status Indicators; Humans; Hypnotics an

2001

Trials

1 trial available for zolpidem and Behavior Disorders

ArticleYear
Sequential psychological and pharmacological therapies for comorbid and primary insomnia: study protocol for a randomized controlled trial.
    Trials, 2016, Mar-03, Volume: 17, Issue:1

    Topics: Adult; Affect; Clinical Protocols; Cognitive Behavioral Therapy; Colorado; Combined Modality Therapy

2016

Other Studies

8 other studies available for zolpidem and Behavior Disorders

ArticleYear
Age cohort differences in the nonmedical use of prescription zolpidem: findings from a nationally representative sample.
    Addictive behaviors, 2014, Volume: 39, Issue:9

    Topics: Adolescent; Adolescent Behavior; Adult; Age Distribution; Child; Cohort Studies; Cross-Sectional Stu

2014
Drug Overdose in a Retrospective Cohort with Non-Cancer Pain Treated with Opioids, Antidepressants, and/or Sedative-Hypnotics: Interactions with Mental Health Disorders.
    Journal of general internal medicine, 2015, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Analgesics, Opioid; Antidepressive Agents; Benzodiazepines; Drug Overdose; Female

2015
Daily episodes of confusion · altered behavior · chronic sleep deprivation · Dx?
    The Journal of family practice, 2015, Volume: 64, Issue:2

    Topics: Confusion; Diagnosis, Differential; Humans; Hypnotics and Sedatives; Male; Medication Errors; Mental

2015
[An Autopsy Case of Abnormal Behaviour Induced by Zolpidem].
    Fukuoka igaku zasshi = Hukuoka acta medica, 2015, Volume: 106, Issue:6

    Topics: Accidents; Aged; Autopsy; Humans; Male; Mental Disorders; Pyridines; Sleep Initiation and Maintenanc

2015
Benzodiazepine and "Z-Drug" Dependence: Data From a Tertiary Care Center.
    The primary care companion for CNS disorders, 2017, Feb-16, Volume: 19, Issue:1

    Topics: Acetamides; Adult; Azabicyclo Compounds; Bacterial Proteins; Benzodiazepines; Female; Humans; Hypnot

2017
Zolpidem ingestion, automatisms, and sleep driving: a clinical and legal case series.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2011, Dec-15, Volume: 7, Issue:6

    Topics: Adult; Aged; Automatism; Automobile Driving; Female; Follow-Up Studies; Headache; Humans; Hypnotics

2011
Development of an LC-MS/MS method for the simultaneous determination of 25 benzodiazepines and zolpidem in oral fluid and its application to authentic samples from regular drug users.
    Journal of pharmaceutical and biomedical analysis, 2013, Feb-23, Volume: 74

    Topics: Benzodiazepines; Chromatography, Liquid; Humans; Mental Disorders; Mouth; Pyridines; Reproducibility

2013
Seizure following sudden zolpidem withdrawal.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Mar-30, Volume: 31, Issue:2

    Topics: Adult; Female; Humans; Hypnotics and Sedatives; Mental Disorders; Pyridines; Seizures; Substance Wit

2007