zolpidem has been researched along with Apnea, Obstructive Sleep in 14 studies
Zolpidem: An imidazopyridine derivative and short-acting GABA-A receptor agonist that is used for the treatment of INSOMNIA.
zolpidem : An imidazo[1,2-a]pyridine compound having a 4-tolyl group at the 2-position, an N,N-dimethylcarbamoylmethyl group at the 3-position and a methyl substituent at the 6-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-one patients with obstructive sleep apnea underwent polysomnography and sleep endoscopy during zolpidem-induced sleep and during DISE with propofol." | 5.56 | Comparison of upper airway obstruction during zolpidem-induced sleep and propofol-induced sleep in patients with obstructive sleep apnea: a pilot study. ( Cahali, MB; Genta, PR; Grad, GF; Lorenzi-Filho, G; Ordones, AB; Sennes, LU, 2020) |
| "Sodium oxybate (SXB) is approved for cataplexy and excessive daytime sleepiness in narcolepsy." | 5.15 | A 2-week, polysomnographic, safety study of sodium oxybate in obstructive sleep apnea syndrome. ( Feldman, N; George, CF; Grzeschik, SM; Inhaber, N; Lai, C; Steininger, TL; Zheng, Y, 2011) |
| "Sodium oxybate (SXB) is an approved drug for the treatment of excessive daytime sleepiness (EDS) and cataplexy in narcolepsy." | 5.14 | A safety trial of sodium oxybate in patients with obstructive sleep apnea: Acute effects on sleep-disordered breathing. ( Feldman, N; George, CF; Grzeschik, SM; Inhaber, N; Lai, C; Steininger, TL; Zheng, Y, 2010) |
| " Pitolisant, a novel histamine-3 receptor antagonist/inverse agonist, gained approval for the treatment of excessive daytime sleepiness in adults with narcolepsy as well as obstructive sleep apnea." | 5.05 | New pharmacologic agents for insomnia and hypersomnia. ( Earl, DC; Van Tyle, KM, 2020) |
| "16 patients with severe obstructive sleep apnea (apnea+ hypopnea index > 30/hr), on CPAP therapy for at least 6 months." | 2.72 | Effect of zolpidem on the efficacy of continuous positive airway pressure as treatment for obstructive sleep apnea. ( Berry, RB; Patel, PB, 2006) |
| "Pretreatment with zolpidem significantly improved polysomnographic quality and may decrease the need to repeat polysomnograms." | 2.71 | Does zolpidem enhance the yield of polysomnography? ( Andrada, T; Eliasson, AH; Khramtsov, A; Kristo, DA; Lettieri, CJ, 2005) |
| "Twenty-one patients with obstructive sleep apnea underwent polysomnography and sleep endoscopy during zolpidem-induced sleep and during DISE with propofol." | 1.56 | Comparison of upper airway obstruction during zolpidem-induced sleep and propofol-induced sleep in patients with obstructive sleep apnea: a pilot study. ( Cahali, MB; Genta, PR; Grad, GF; Lorenzi-Filho, G; Ordones, AB; Sennes, LU, 2020) |
| "A total of 26 confirmed obstructive sleep apnea patients were recruited in this one-year study." | 1.56 | Tongue imaging during drug-induced sleep ultrasound in obstructive sleep apnea patients. ( Abuan, MRA; Chen, NH; Fang, TJ; Hsin, LJ; Lee, LA; Li, HY; Lin, WN; Lo, YL, 2020) |
| "Zolpidem was well tolerated and significantly improved the sleep efficiency compared with the no-drug night (77 ± 12% versus 84 ± 9%, p = 0." | 1.51 | The effects of zolpidem in obstructive sleep apnea - An open-label pilot study. ( Carberry, JC; Eckert, DJ; Grunstein, RR, 2019) |
| "Consecutive patients with suspected obstructive sleep apnea (OSA) referred for polysomnography (PSG) had demographic and PSG data abstracted." | 1.46 | Eszopiclone and Zolpidem Do Not Affect the Prevalence of the Low Arousal Threshold Phenotype. ( Andrada, TF; Bridges, E; Costan-Toth, C; Forsthoefel, D; Holley, AB; Sheikh, KL; Smith, PR, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 4 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Ordones, AB | 1 |
| Grad, GF | 1 |
| Cahali, MB | 1 |
| Lorenzi-Filho, G | 1 |
| Sennes, LU | 1 |
| Genta, PR | 1 |
| Abuan, MRA | 1 |
| Lin, WN | 1 |
| Hsin, LJ | 1 |
| Lee, LA | 1 |
| Fang, TJ | 1 |
| Chen, NH | 1 |
| Lo, YL | 1 |
| Li, HY | 1 |
| Earl, DC | 1 |
| Van Tyle, KM | 1 |
| Messineo, L | 1 |
| Carter, SG | 1 |
| Taranto-Montemurro, L | 1 |
| Chiang, A | 1 |
| Vakulin, A | 1 |
| Adams, RJ | 1 |
| Carberry, JC | 3 |
| Eckert, DJ | 3 |
| Fisher, LP | 1 |
| Grunstein, RR | 2 |
| Gandevia, SC | 1 |
| McKenzie, DK | 1 |
| Butler, JE | 1 |
| Smith, PR | 1 |
| Sheikh, KL | 1 |
| Costan-Toth, C | 1 |
| Forsthoefel, D | 1 |
| Bridges, E | 1 |
| Andrada, TF | 1 |
| Holley, AB | 1 |
| George, CF | 2 |
| Feldman, N | 2 |
| Inhaber, N | 2 |
| Steininger, TL | 2 |
| Grzeschik, SM | 2 |
| Lai, C | 2 |
| Zheng, Y | 2 |
| Dopp, JM | 1 |
| Morgan, BJ | 1 |
| Berry, RB | 1 |
| Patel, PB | 1 |
| Bradshaw, DA | 1 |
| Ruff, GA | 1 |
| Murphy, DP | 1 |
| Pelayo, R | 1 |
| Guilleminault, C | 1 |
| Lettieri, CJ | 1 |
| Eliasson, AH | 1 |
| Andrada, T | 1 |
| Khramtsov, A | 1 |
| Kristo, DA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison Between Natural Sleep Endoscopy and Drug-induced Sleep Endoscopy Among Obstructive Sleep Apnea Subjects Referred for Surgical Treatment[NCT03004014] | 28 participants (Actual) | Interventional | 2015-01-31 | Completed | |||
| Prospective, Randomized, Placebo Controlled Trial Assessing the Effects of Ezopiclone on the Quality of Overnight Polysomnography and CPAP Titration[NCT00507117] | Phase 4 | 300 participants (Anticipated) | Interventional | 2007-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for zolpidem and Apnea, Obstructive Sleep
| Article | Year |
|---|---|
New pharmacologic agents for insomnia and hypersomnia.
Topics: Azepines; Carbamates; Dementia; Disorders of Excessive Somnolence; GABA-A Receptor Agonists; Humans; | 2020 |
Pharmacologic approaches for the management of symptoms and cardiovascular consequences of obstructive sleep apnea in adults.
Topics: Benzhydryl Compounds; Cardiovascular Diseases; Central Nervous System Stimulants; Combined Modality | 2010 |
7 trials available for zolpidem and Apnea, Obstructive Sleep
| Article | Year |
|---|---|
Addition of zolpidem to combination therapy with atomoxetine-oxybutynin increases sleep efficiency and the respiratory arousal threshold in obstructive sleep apnoea: A randomized trial.
Topics: Arousal; Atomoxetine Hydrochloride; Humans; Mandelic Acids; Sleep; Sleep Apnea, Obstructive; Zolpide | 2021 |
Role of common hypnotics on the phenotypic causes of obstructive sleep apnoea: paradoxical effects of zolpidem.
Topics: Adult; Arousal; Azabicyclo Compounds; Continuous Positive Airway Pressure; Cross-Over Studies; Doubl | 2017 |
A safety trial of sodium oxybate in patients with obstructive sleep apnea: Acute effects on sleep-disordered breathing.
Topics: Adjuvants, Anesthesia; Adult; Aged; Benzhydryl Compounds; Central Nervous System Stimulants; Comorbi | 2010 |
A 2-week, polysomnographic, safety study of sodium oxybate in obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Benzhydryl Compounds; Central Nervous System Stimulants; Combined Moda | 2011 |
Effect of zolpidem on the efficacy of continuous positive airway pressure as treatment for obstructive sleep apnea.
Topics: Adult; Arousal; Body Mass Index; Combined Modality Therapy; Continuous Positive Airway Pressure; Cro | 2006 |
An oral hypnotic medication does not improve continuous positive airway pressure compliance in men with obstructive sleep apnea.
Topics: Administration, Oral; Adult; Continuous Positive Airway Pressure; Humans; Hypnotics and Sedatives; M | 2006 |
Does zolpidem enhance the yield of polysomnography?
Topics: Adult; Continuous Positive Airway Pressure; Demography; Female; Humans; Laboratories; Male; Middle A | 2005 |
5 other studies available for zolpidem and Apnea, Obstructive Sleep
| Article | Year |
|---|---|
Comparison of upper airway obstruction during zolpidem-induced sleep and propofol-induced sleep in patients with obstructive sleep apnea: a pilot study.
Topics: Airway Obstruction; Endoscopy; Humans; Pilot Projects; Propofol; Sleep; Sleep Apnea, Obstructive; Zo | 2020 |
Tongue imaging during drug-induced sleep ultrasound in obstructive sleep apnea patients.
Topics: Adult; Body Mass Index; Female; Humans; Male; Middle Aged; Mouth; Polysomnography; Regression Analys | 2020 |
The effects of zolpidem in obstructive sleep apnea - An open-label pilot study.
Topics: Female; Humans; Male; Middle Aged; Pilot Projects; Sleep Aids, Pharmaceutical; Sleep Apnea, Obstruct | 2019 |
Eszopiclone and Zolpidem Do Not Affect the Prevalence of the Low Arousal Threshold Phenotype.
Topics: Adult; Arousal; Eszopiclone; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Phenotype; | 2017 |
The role of hypnotics in continuous positive airway pressure compliance.
Topics: Continuous Positive Airway Pressure; Humans; Hypnotics and Sedatives; Patient Compliance; Pyridines; | 2007 |