zolpidem has been researched along with Alcoholism in 15 studies
Zolpidem: An imidazopyridine derivative and short-acting GABA-A receptor agonist that is used for the treatment of INSOMNIA.
zolpidem : An imidazo[1,2-a]pyridine compound having a 4-tolyl group at the 2-position, an N,N-dimethylcarbamoylmethyl group at the 3-position and a methyl substituent at the 6-position.
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Zolpidem and alcohol were rated more unfavorably than placebo on the POMS." | 2.69 | The abuse potential of zolpidem administered alone and with alcohol. ( Wilkinson, CJ, 1998) |
| "Alcohol use disorders are chronic debilitating diseases characterized by severe withdrawal symptoms that contribute to morbidity and relapse." | 1.48 | Histone deacetylases mediate GABA ( Besheer, J; Bohnsack, JP; Edokpolor, K; Hughes, BA; Morrow, AL; O'Buckley, TK, 2018) |
| "[3H]Zolpidem binding was increased in the inferior colliculus and substantia nigra, and decreased in the medial septum." | 1.29 | Regional differences in the effects of chronic ethanol administration on [3H]zolpidem binding in rat brain. ( Breese, GR; Criswell, HE; Devaud, LL; Duncan, GE; Morrow, AL, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (53.33) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yin, W | 1 |
| Majumder, S | 1 |
| Clayton, T | 1 |
| Petrou, S | 1 |
| VanLinn, ML | 1 |
| Namjoshi, OA | 1 |
| Ma, C | 1 |
| Cromer, BA | 1 |
| Roth, BL | 1 |
| Platt, DM | 1 |
| Cook, JM | 1 |
| Mills, WD | 1 |
| Greenhaw, RM | 1 |
| Wang, JMP | 1 |
| Bohnsack, JP | 1 |
| Hughes, BA | 1 |
| O'Buckley, TK | 1 |
| Edokpolor, K | 1 |
| Besheer, J | 1 |
| Morrow, AL | 3 |
| Hoch, HJ | 1 |
| Gehring, C | 1 |
| Liang, J | 1 |
| Cagetti, E | 1 |
| Olsen, RW | 1 |
| Spigelman, I | 1 |
| Vadhan, NP | 1 |
| Hart, CL | 1 |
| Roe, B | 1 |
| Colley, J | 1 |
| Haney, M | 1 |
| Foltin, RW | 1 |
| Wang, WT | 1 |
| Chen, YY | 1 |
| Wu, SL | 1 |
| Wei, TS | 1 |
| Liu, SY | 1 |
| Devaud, LL | 2 |
| Criswell, HE | 1 |
| Breese, GR | 1 |
| Duncan, GE | 1 |
| Undén, M | 1 |
| Bucci, D | 1 |
| Smith, FD | 1 |
| Lewohl, JM | 2 |
| Crane, DI | 1 |
| Dodd, PR | 2 |
| Wilkinson, CJ | 1 |
| Mehta, AK | 1 |
| Ticku, MK | 1 |
| Keller, T | 1 |
| Schneider, A | 1 |
| Tutsch-Bauer, E | 1 |
1 trial available for zolpidem and Alcoholism
| Article | Year |
|---|---|
The abuse potential of zolpidem administered alone and with alcohol.
Topics: Adult; Affect; Alcoholism; Cross-Over Studies; Double-Blind Method; Drug Interactions; Ethanol; Huma | 1998 |
14 other studies available for zolpidem and Alcoholism
| Article | Year |
|---|---|
Design, synthesis, and subtype selectivity of 3,6-disubstituted β-carbolines at Bz/GABA(A)ergic receptors. SAR and studies directed toward agents for treatment of alcohol abuse.
Topics: Alcoholism; Animals; Benzodiazepines; Binding Sites; Carbolines; Cell Line; Computer Simulation; GAB | 2010 |
A Medical Review of Fatal High-G U.S. Aerobatic Accidents.
Topics: Accidents, Aviation; Aerospace Medicine; Alcoholism; Alprazolam; Case-Control Studies; Clonidine; Da | 2019 |
Histone deacetylases mediate GABA
Topics: Acetylation; Alcoholism; Animals; Cerebral Cortex; Ethanol; Histone Deacetylase 2; Histone Deacetyla | 2018 |
[High-dose zolpidem dependence].
Topics: Alcoholism; Benzodiazepines; Comorbidity; Dose-Response Relationship, Drug; Drug Tolerance; Female; | 2013 |
Altered pharmacology of synaptic and extrasynaptic GABAA receptors on CA1 hippocampal neurons is consistent with subunit changes in a model of alcohol withdrawal and dependence.
Topics: Alcoholism; Animals; Azides; Benzodiazepines; Diazepam; Drug Interactions; Ethanol; GABA Agonists; H | 2004 |
Substance use and psychosocial outcomes following participation in residential laboratory studies of marijuana, methamphetamine and zolpidem.
Topics: Alcoholism; Costs and Cost Analysis; Dopamine Agents; Humans; Hypnotics and Sedatives; Marijuana Abu | 2006 |
Zolpidem dramatically improved motor and speech function in a patient with central pontine myelinolysis.
Topics: Alcoholism; Female; Humans; Middle Aged; Motor Skills Disorders; Myelinolysis, Central Pontine; Pyri | 2007 |
Regional differences in the effects of chronic ethanol administration on [3H]zolpidem binding in rat brain.
Topics: Alcoholism; Animals; Autoradiography; Brain; Brain Mapping; Hypnotics and Sedatives; Male; Pyridines | 1995 |
[Significance of the sedative zolpidem in combination with alcohol and benzodiazepines in patients with physical dependence].
Topics: Adult; Alcoholism; Benzodiazepines; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hy | 1993 |
GABAA and NMDA receptor subunit mRNA expression in ethanol dependent rats.
Topics: Alcoholism; Animals; Azides; Base Sequence; Benzodiazepines; Cerebellum; Cerebral Cortex; Dizocilpin | 1994 |
Zolpidem binding sites on the GABA(A) receptor in brain from human cirrhotic and non-cirrhotic alcoholics.
Topics: Adult; Aged; Aged, 80 and over; Alcoholism; Binding Sites; Brain; Female; Flunitrazepam; Frontal Lob | 1997 |
Cell death mediated by amino acid transmitter receptors in human alcoholic brain damage: conflicts in the evidence.
Topics: Alcoholism; Binding, Competitive; Brain; Cadaver; Cell Death; Humans; Liver Cirrhosis, Alcoholic; Py | 1998 |
Prevalence of the GABAA receptor assemblies containing alpha1-subunit in the rat cerebellum and cerebral cortex as determined by immunoprecipitation: lack of modulation by chronic ethanol administration.
Topics: Affinity Labels; Alcoholism; Animals; Azides; Benzodiazepines; Brain Chemistry; Central Nervous Syst | 1999 |
GC/MS determination of zolpidem in postmortem specimens in a voluntary intoxication.
Topics: Alcoholism; Autopsy; Drug Overdose; Fatal Outcome; Female; Gas Chromatography-Mass Spectrometry; Gas | 1999 |