zolmitriptan has been researched along with Migraine Disorders in 248 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 66 (26.61) | 18.2507 |
| 2000's | 127 (51.21) | 29.6817 |
| 2010's | 47 (18.95) | 24.3611 |
| 2020's | 8 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Buckingham, J; Glen, RC; Hill, AP; Hyde, RM; Martin, GR; Robertson, AD; Salmon, JA; Woollard, PM | 1 |
| Barrett, V; Brockwell, M; Cambridge, D; Farrant, DR; Foster, C; Giles, H; Glen, RC; Hill, AP; Hobbs, H; Honey, A; Jandu, KS; Martin, GR; Salmon, J; Selwood, DL; Smith, D; Woollard, P | 1 |
| Bell, IM | 1 |
| Jha, S; Mishra, D | 1 |
| McVige, J; Visser, H; Yonker, ME; Zeitlin, L | 1 |
| Agrawal, A; Chanchlani, R; Hafsa, SN; Janjua, D | 1 |
| Duan, S; Li, G; Liu, L; Liu, Z; Ren, Z; Wang, Z; Xia, H; Zhu, T | 1 |
| Bukka, R; Khezri, FANZ; Lakshmi, CSR; Nargund, SL; Nidhi, M | 1 |
| Abdou, EM | 1 |
| El-Nabarawy, NA; Helal, DA; Teaima, MH | 1 |
| Ameri, M; Kellerman, DJ; Lewis, H; Rapoport, AM | 1 |
| Amundsen, S; Fuskevåg, OM; Nordeng, H; Nordmo, E; Sager, G; Spigset, O | 1 |
| Elbuluk, N; Foreman, PK; Friedman, DI; Hindiyeh, N; Kellerman, DJ; Nahas, SJ; Schmidt, P | 1 |
| Baradia, D; Dobaria, N; Ghoghari, A; Laddha, R; Mehta, P; Modi, N; Patel, H; Patel, P; Shah, S; Srinivas, NR; Variya, B | 1 |
| Al-Huniti, N; Birmingham, B; Li, J; Lillieborg, S; Xu, H; Zhou, D; Zhou, W | 1 |
| Abdou, EM; Kandil, SM; Miniawy, HMFE | 1 |
| Ameri, M; Kellerman, DJ; Tepper, SJ | 1 |
| Lee, JTL; Lin, ML; Skalicky, SE | 1 |
| Brandes, JL; Kellerman, DJ; Kudrow, DB; Schmidt, PC; Spierings, EL; Tepper, SJ; Weintraub, J | 1 |
| Dudhipala, N; Narala, A; Pitta, SK; Veerabrahma, K | 1 |
| Ameri, M; Diep, AN; Hochart, G; Lewis, H; Nguyen, J; Queja, A | 1 |
| Dodick, DW; Friedman, DI; Gelfand, AA; Kellerman, DJ; Schmidt, PC; Tepper, SJ | 1 |
| Dodick, DW; Kellerman, DJ; Schmidt, PC; Tepper, SJ | 1 |
| Cutler, H; Gauld, N; Gumbie, M; Haywood, P; Mumford, V; Parkinson, B | 1 |
| Allais, G; Benedetto, C; Bussone, G; Omboni, S; Pezzola, D; Tullo, V; Zava, D | 1 |
| Allais, G; Barbanti, P; Benedetto, C; Bussone, G; Cortelli, P; Curone, M; Omboni, S; Peccarisi, C; Pezzola, D; Tullo, V; Zava, D | 1 |
| Evers, S | 1 |
| Chen, S; Rapoport, AM; Reidenbach, F; Tepper, SJ | 1 |
| Hariharakrishnan, V; Ravikumar, K; Sridhar, B | 1 |
| Kaur, G; Kaur, K | 1 |
| Christie, M; Dubey, R; Martini, LG | 1 |
| Cui, XP; Lin, H; Lin, M; Mu, JS; Ye, JX | 1 |
| Bird, S; Derry, S; Moore, RA | 1 |
| Baudoin, Y; Guilhem, K; Meyrat, L; Thouard, H | 1 |
| Best, C; Birklein, F; Döring, K; Krämer, HH | 1 |
| Kitagawa, Y; Suzuki, Y; Takayanagi, R; Tokuoka, K; Watanabe, M; Yamada, Y | 1 |
| Garg, T; Goyal, AK; Kumar, A; Rath, G; Sarma, GS | 1 |
| Girotra, P; Kumar, G; Singh, SK | 1 |
| McKeage, K | 1 |
| Abd-Elal, RM; Bendas, ER; Rashed, HM; Shamma, RN | 1 |
| Han, W; Li, M; Wang, J; Xu, H | 1 |
| Isildak, H; O'Connell Ferster, AP; Priesol, AJ | 1 |
| Emeribe, U; Hee, A; Silberstein, S; Tuchman, MM | 1 |
| Assaid, C; Dodick, DW; Fan, X; Ferrari, MD; Froman, S; Galet, V; Ho, TW; Koppen, H; Kost, J; Leibensperger, H; Lines, C; Winner, PK | 1 |
| Edvinsson, L | 1 |
| Tfelt-Hansen, P | 1 |
| Jamieson, DG | 1 |
| Iversen, HK; Olesen, J; Tfelt-Hansen, P; Tvedskov, JF | 1 |
| Autret-Leca, E; Beau-Salinas, F; Bensouda-Grimaldi, L; Cissoko, H; Jonville-Béra, AP | 1 |
| Dandekar, P; Jain, R; Nabar, S; Patravale, V | 1 |
| Edvinsson, L; Hargreaves, RJ; Kane, SA; Lynch, JJ; Regan, CP | 1 |
| Allais, G; Benedetto, C; Bussone, G; Curone, M; Ferrari, MD; Mea, E; Omboni, S; Tullo, V; Zava, D | 1 |
| Assaid, C; Dodick, DW; Ho, TW; Kost, J; Lines, C | 1 |
| Dodick, DW; Ferrari, MD; Ho, TW; Kost, J; Lines, C; Olesen, J | 1 |
| Allais, G; Benedetto, C; Bussone, G; Omboni, S; Tullo, V; Zava, D | 1 |
| Airaksinen, M; Hoppu, K; Kaukonen, AM; Klaukka, T; Lindkvist, J | 1 |
| Golwala, H; Lozano, P; Smith, M | 1 |
| Mahmoud, AA; Salah, S | 1 |
| Bertschi, M; Hess, CW; Sturzenegger, M | 1 |
| Casolla, B; D'Alonzo, L; Lionetto, L; Martelletti, P; Mastropietri, F; Negro, A; Simmaco, M | 1 |
| Weidmann, P | 1 |
| Alhalaweh, A; Bandiera, P; Beggiato, S; Dalpiaz, A; Ferraro, L; Gavini, E; Giunchedi, P; Marchetti, N; Rassu, G; Velaga, S | 1 |
| Fukuuchi, Y; Itoyama, Y; Iwata, M; Morimatsu, M; Nakashima, K; Sakai, F; Sobue, G; Tashiro, K; Tsuji, S | 1 |
| Rapoport, AM; Sheftell, FD; Tepper, SJ | 1 |
| Csiba, L; Ficzere, A | 1 |
| Bussone, G; D'Amico, D; Gerth, W; Lines, CR; McCarroll, KA | 1 |
| Boes, CJ; Goadsby, PJ | 1 |
| Aubel, B; Bourgoin, S; Hamon, M; Kayser, V | 1 |
| Vaitkus, A; Vilionskis, A | 1 |
| Boutilier, AS; Gardner, DM | 1 |
| Lempert, T; Neuhauser, H; Radtke, A; von Brevern, M | 1 |
| Stöckli, HR; Sword, A | 1 |
| Adelman, JU; Lewit, EJ | 1 |
| Becker, WJ; Boes-Hansen, S; Charlesworth, BR; Dowson, AJ; Färkkilä, M; Purdy, A | 2 |
| Ashkenazi, A; Silberstein, SD | 1 |
| Brandes, J; Eikermann, A; MacGregor, EA | 1 |
| Diener, HC; Giffin, N; Katsarava, Z; Kaube, H | 1 |
| Gawel, M; Gladstone, JP | 1 |
| Charlesworth, BR; Dowson, AJ | 1 |
| Abu-Shakra, S; Syrett, N; Yates, R | 1 |
| Dahlöf, C | 3 |
| Diksic, M; Dobson, CF; Hamel, E; Tohyama, Y | 1 |
| Burstein, R; Collins, B; Jakubowski, M | 1 |
| Abu-Shakra, S; Loder, E; Mueller, L; Silberstein, SD; Smith, T | 1 |
| Diener, HC; MacGregor, EA; Muirheads, N; Schoenen, J; Sikes, CR; Steiner, TJ | 1 |
| Ashcroft, DM; Millson, D | 1 |
| Bigal, ME; Goadsby, PJ; Lipton, RB | 1 |
| Lines, C; Visser, WH | 1 |
| Baykal, C; Baykal, Y; Cem, B; Yeşim, B | 1 |
| Bravo, MS; Carnero, M; Corredera, E; Escribano, JL; Maciñeiras, JL; Romero, J | 1 |
| Brandes, J; Eikermann, A; Giammarco, R; MacGregor, EA | 1 |
| Bigal, ME; Rapoport, AM; Sheftell, FD; Tepper, SJ | 2 |
| Diener, HC; Evers, S; Gendolla, A | 1 |
| Charlesworth, B; Klapper, J; Lucas, C; Røsjø, Ø | 1 |
| Brandes, J; Gendolla, A; Giammarco, R; MacGregor, EA | 1 |
| Kato, K | 1 |
| Manaka, S | 1 |
| Kowa, H; Nakashima, K; Takeshima, T | 1 |
| Igarashi, H | 1 |
| Morillo, LE | 2 |
| Muñoz, P; Pascual, J | 1 |
| Aschoff, J; Charlesworth, BR; Gawel, M; May, A | 2 |
| Charlesworth, BR; Diener, HC; Dowson, AJ; Färkkilä, M; Gawel, M; Green, J; Hansen, SB | 1 |
| Brandes, J; Dodick, D; Elkind, A; Mathew, N; Rodichok, L | 1 |
| Abu-Shakra, S; Adelman, J; Freitag, FG; Loder, E; Pearlmand, S | 1 |
| Gawel, M; Worthington, I | 1 |
| Capuano, A; Di Trapani, G; Evangelista, M; Ferraro, D; Mei, D; Pierguidi, L; Vollono, C | 1 |
| Lewis, DW; Sowell, M; Winner, P; Yonker, M | 1 |
| Dowson, AJ; Loder, EW; Spierings, EL | 1 |
| Almqvist, P; Dowson, AJ | 1 |
| Diener, HC; Gendolla, A | 1 |
| Deixler, E; Helmke, K | 1 |
| Lewis, D; Rothner, AD; Stankowski, J; Wasiewski, W; Winner, P | 1 |
| Goadsby, PJ; Yates, R | 1 |
| Galbut, BH; Galbut, EJ; Kavinsky, CJ; McMullan, PW; Pacheco-Coronado, R; Schaer, GL; Snell, J | 1 |
| Auvin, S; Cuvellier, JC; Joriot, S; Vallée, L | 1 |
| Fulton, JA; Hoffman, RS; Kahn, J; Nelson, LS | 1 |
| Acuto, G; Allais, G; Benedetto, C; Bussone, G; Cabarrocas, X; Esbri, R | 1 |
| Debus, O; Evers, S; Frese, A; Husstedt, IW; Kraemer, C; Kurlemann, G; Rahmann, A | 1 |
| Kanwar, VS; Pearce, J | 1 |
| Caminero, AB; Díaz-Insa, S; Huerta, M; Jurado, C; Navarro, A; Pascual, J | 1 |
| Almqvist, P; Dowson, A; Lacoste, JP; Shapero, G | 1 |
| Emeribe, U; Hee, A; Silberstein, S; Tuchman, M | 1 |
| Cunha, L; Dahlöf, CG; Diener, HC; Dowson, AJ; Färkkilä, M; Goadsby, PJ; Manzoni, GC; Massiou, H; Mateos, V; Pascual, J; Raets, I | 1 |
| Kornblau, DH | 1 |
| Buhler, L; Hadaya, K; Malacarne, S; Martin, PY; Moll, S | 1 |
| Hershey, AD; Lewis, DW; Wasiewski, WW; Winner, P | 1 |
| Jung, S | 1 |
| Gano, D; Gerretsen, P; Silver, S | 1 |
| Bundy, M; Dowson, A; Kilminster, S; Salt, R | 1 |
| Peterlin, BL; Rapoport, AM | 1 |
| Ashcroft, DM; Chen, LC | 1 |
| Martino, G; Perkins, MN | 1 |
| Cox, RC; Ferrari, MD; Jones, D; Klein, KB; Visser, WH | 1 |
| Ferrari, MD | 3 |
| Earl, NL | 1 |
| Martin, GR | 2 |
| Geraud, GE | 1 |
| Dowson, A | 1 |
| Edmeads, JG | 1 |
| Bendtsen, L; Daugaard, D; Dixon, R; Gibbens, M; Langemark, M; Lassen, LH; Olesen, J; Thomsen, LL | 1 |
| Churchus, R; On, N; Phillips, S; Posner, J; Rolan, P; Seaber, E | 1 |
| Goadsby, PJ; Hoskin, KL | 2 |
| Goadsby, PJ; Olesen, J | 1 |
| Zagami, AS | 2 |
| Dowson, AJ | 1 |
| Dixon, R; Gibbens, M; Gillotin, C; Peck, RW; Posner, J | 1 |
| Chittick, G; Dixon, RM; Gibbens, M; Leavens, WJ; Liptrot, J; On, N; Pack, RW; Posner, J; Rolan, PE; Seaber, E | 1 |
| Goadsby, PJ | 3 |
| Schoenen, J | 1 |
| Cutrer, FM; Moskowitz, MA | 1 |
| Cady, RK; Earl, NL; Klapper, JA; Ramadan, NM; Saper, JR; Solomon, GD | 1 |
| Adelman, JU; Earl, NL; Elkind, AH; Kudrow, DB; Mathew, NT; Ramadan, NM; Rapoport, AM | 1 |
| Mathew, N | 1 |
| Dixon, R; Warrander, A | 1 |
| Rolan, P | 1 |
| Sawyer, J; Schoenen, J | 1 |
| Lipton, RB; Stewart, WF | 1 |
| Bagnis, C; Deray, G; Gillotin, C; Mamet, JP; Peck, RW | 1 |
| Afra, J; Proietti-Cecchini, A; Schoenen, J | 1 |
| Layton, G; Peck, RW; Posner, J; Ridout, G; Seaber, EJ | 1 |
| Arnold, G; Back, T; Dirnagl, U; Dreier, J; Einhäupl, KM; Gold, L; Reuter, U | 1 |
| Guanci, R; Lilley, LL | 1 |
| Pascual, J | 1 |
| Leira, R; Noya, M | 1 |
| Morales Asín, F | 1 |
| Cambridge, D; MacLennan, SJ; Marston, C; Martin, GR; Whiting, MV | 1 |
| Cumberbatch, MJ; Hargreaves, RJ; Hill, RG | 1 |
| Monseu, G; Sternon, J | 1 |
| Diener, HC; Fritsche, G; Kazarawa, Z; Limmroth, V | 1 |
| Cummings, L; Dane, A; Dixon, R; Hughes, AM; Kemp, J; Yates, RA | 1 |
| Dixon, R; Engleman, K; Kemp, J; Ruckle, JL | 1 |
| Deleu, D; Hanssens, Y | 2 |
| Gunasekara, NS; Hills, C; Spencer, CM | 1 |
| Diener, HC; Limmroth, V | 1 |
| Buzzi, MG | 1 |
| Le Jeunne, C | 1 |
| Dixon, R | 1 |
| Diener, HC; Dowson, AJ; Ferrari, M; Nappi, G; Tfelt-Hansen, P | 1 |
| Amelin, AV; Korenko, LA; Skoromets, AA | 1 |
| Bartlett, MG; Stewart, JT; Vishwanathan, K | 1 |
| Bomhof, MA; Donnan, GA; Dowson, AJ; Elkind, A; Fletcher, PE; Meloche, J; Millson, DS; Tepper, SJ | 1 |
| Edvinsson, L; Geraud, G; Korczyn, A; Mauskop, A; Pfaffenrath, V; Tuchman, M | 1 |
| Farkkila, M; Hering-Hanit, R; Mauskop, A; Rapoport, A; Warner, J | 1 |
| Logemann, CD; Rankin, LM | 1 |
| Nater, B; Regli, F | 1 |
| Peacock, JH; Vijayan, N | 1 |
| Chitra, R; Dennish, G; Gallagher, RM; Spierings, EL | 1 |
| Duckmanton, L | 1 |
| Diener, HC; Geraud, G; Olesen, J; Pfaffenrath, V; Sweet, R; Tfelt-Hansen, P; Zupping, R | 1 |
| Chernyshev, O; Gentry, P; Kailasam, J; Mathew, NT | 1 |
| de Tommaso, M; Guido, M; Libro, G; Puca, F; Sciruicchio, V | 1 |
| Bartleson, JD | 1 |
| Allen, C; Diener, HC; Pascual, J; Patel, K; Vega, P; Vrijens, F | 1 |
| de Hoon, JN; Struijker-Boudier, HA; Troost, J; Van Bortel, LM; Willigers, JM | 1 |
| Scholz, M | 1 |
| Dowson, AJ; Linder, SL | 1 |
| Prusiński, A | 1 |
| Potrebic, S; Raskin, NH | 1 |
| Croft, P; Frischer, M; Goadsby, PJ; Millson, D | 1 |
| McGinnis, J; Seaton, TL | 1 |
| Becker, WJ | 1 |
| Gruffyd-Jones, K; Kies, B; Middleton, A; Millson, DS; Mulder, LJ; Røsjø , Ø | 1 |
| Hashimoto, S; Iwata, M | 1 |
| Marcus, DA | 1 |
| Leira, R; Muñoz, R; Pascual, J | 1 |
| Saper, JR | 1 |
| Goadsby, PJ; Jiang, K; Lines, CR; Lipton, RB; Massiou, H; McCarroll, KA; Pascual, J; Vandormael, K | 1 |
| Dowson, AJ; Rapoport, AM; Sawyer, J; Williams, P | 1 |
| Adelman, JU; Diener, HC; Ferrari, MD; Lines, CR; Lipton, RB; McCarroll, KA; Vandormael, K | 1 |
| Billeter, M; Daems, K; Sturzenegger, M | 1 |
| Compagnon, A; Geraud, G; Rossi, A | 1 |
| Henry, P | 1 |
| Meddis, D; Millson, D; Poole, L; Sculpher, M | 1 |
| Freitag, FG | 1 |
| Diener, HC; Drepper, J; Ellrich, J; Katsarava, Z; Kaube, H; Przywara, S | 1 |
| Becker, WJ; Dowson, AJ; Green, J; Levy, SL; MacGregor, EA; Purdy, RA | 1 |
| Bellaïche, G; Boucard, M; Ley, G; Radu, B; Slama, JL | 1 |
| Fité, B; López-Gil, A; Pascual, J | 1 |
| Charlesworth, B; Dowson, AJ | 1 |
67 review(s) available for zolmitriptan and Migraine Disorders
| Article | Year |
|---|---|
Calcitonin gene-related peptide receptor antagonists: new therapeutic agents for migraine.
Topics: Amino Acid Sequence; Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Clinical Trials as Topic; Drug Discovery; Humans; Migraine Disorders; Molecular Sequence Data; Receptors, Calcitonin Gene-Related Peptide; Structure-Activity Relationship | 2014 |
The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review.
Topics: Adolescent; Child; Headache; Humans; Migraine Disorders; Naproxen; Sumatriptan; Tryptamines | 2023 |
Efficacy and safety of intranasal agents for the acute treatment of migraine: a systematic review and network meta-analysis.
Topics: Adult; Humans; Migraine Disorders; Nasal Sprays; Network Meta-Analysis; Oxazolidinones | 2023 |
Efficacy of frovatriptan and other triptans in the treatment of acute migraine of hypertensive and normotensive subjects: a review of randomized studies.
Topics: Carbazoles; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Migraine Disorders; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Triazoles; Tryptamines | 2013 |
The efficacy of triptans in childhood and adolescence migraine.
Topics: Adolescent; Analgesics; Child; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Germany; Humans; Male; Migraine Disorders; Oxazolidinones; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2013 |
Intranasal zolmitriptan for the treatment of acute migraine.
Topics: Administration, Intranasal; Animals; Clinical Trials as Topic; Humans; Migraine Disorders; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Treatment Outcome; Tryptamines | 2013 |
Efficacy, safety, and tolerability of telcagepant in the treatment of acute migraine: a meta-analysis.
Topics: Acute Disease; Azepines; Calcitonin Gene-Related Peptide Receptor Antagonists; Humans; Imidazoles; Migraine Disorders; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Treatment Outcome; Triazoles; Tryptamines | 2015 |
Zolmitriptan for acute migraine attacks in adults.
Topics: Acute Pain; Administration, Oral; Adult; Humans; Migraine Disorders; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin 5-HT1 Receptor Agonists; Time Factors; Tryptamines | 2014 |
Zolmitriptan Nasal Spray: A Review in Acute Migraine in Pediatric Patients 12 Years of Age or Older.
Topics: Administration, Intranasal; Child; Humans; Migraine Disorders; Nasal Sprays; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines; United States | 2016 |
Network meta-analysis of migraine disorder treatment by NSAIDs and triptans.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Migraine Disorders; Oxazolidinones; Pyrrolidines; Randomized Controlled Trials as Topic; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2016 |
The clinical manifestations of vestibular migraine: A review.
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Dizziness; Headache; Humans; Migraine Disorders; Oxazolidinones; Quality of Life; Serotonin 5-HT1 Receptor Agonists; Tryptamines; Vertigo; Vestibular Diseases | 2017 |
Mechanisms of action of the 5-HT1B/1D receptor agonists.
Topics: Carbazoles; Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2002 |
[Treatment of migraine in patients with hypertension and ischemic heart disease].
Topics: Adjuvants, Pharmaceutic; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Contraindications; Dihydroergotamine; Dopamine Agonists; Ergotamine; Humans; Hypertension; Indoles; Migraine Disorders; Myocardial Ischemia; Oxazolidinones; Retrospective Studies; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents | 2002 |
Zolmitriptan: differences from sumatriptan.
Topics: Cluster Headache; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2001 |
[The problems of migraine headache treatment].
Topics: Aged; Analgesics; Analgesics, Non-Narcotic; Aspirin; Dihydroergotamine; Female; Humans; Male; Methysergide; Migraine Disorders; Oxazolidinones; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Psychological; Sumatriptan; Time Factors; Tryptamines; Vasoconstrictor Agents | 2002 |
Reassessing the contraindication of zolmitriptan and serotonin reuptake inhibitors: an evidence-based pharmacotherapeutic case report.
Topics: Contraindications; Depression; Drug Interactions; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Paroxetine; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Serotonin Syndrome; Tryptamines | 2003 |
Comparative aspects of triptans in treating migraine.
Topics: Carbazoles; Cardiovascular Diseases; Humans; Indoles; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Piperidines; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2001 |
The evolving management of migraine.
Topics: Angiotensin Receptor Antagonists; Anticonvulsants; Antipsychotic Agents; Botulinum Toxins, Type A; Carbazoles; Droperidol; Fructose; Humans; Indoles; Migraine Disorders; Neuromuscular Agents; Oxazolidinones; Pyrrolidines; Serotonin Receptor Agonists; Topiramate; Tryptamines | 2003 |
Newer formulations of the triptans: advances in migraine management.
Topics: Analgesics; Area Under Curve; Chemistry, Pharmaceutical; Humans; Migraine Disorders; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Treatment Outcome; Triazoles; Tryptamines | 2003 |
Clinical applications of new therapeutic deliveries in migraine.
Topics: Administration, Intranasal; Administration, Oral; Adult; Clinical Trials as Topic; Dysgeusia; Female; Humans; Injections, Subcutaneous; Male; Middle Aged; Migraine Disorders; Nausea; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tablets; Tryptamines; Vasoconstrictor Agents | 2003 |
Naratriptan for the treatment of acute migraine: meta-analysis of randomised controlled trials.
Topics: Dose-Response Relationship, Drug; Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2004 |
Double-blind clinical trials of oral triptans vs other classes of acute migraine medication - a review.
Topics: Administration, Oral; Analgesics; Double-Blind Method; Humans; Indoles; Migraine Disorders; Oxazolidinones; Pyrrolidines; Randomized Controlled Trials as Topic; Sumatriptan; Tryptamines | 2004 |
Intranasal medications for the treatment of migraine and cluster headache.
Topics: Administration, Intranasal; Analgesics; Capsaicin; Cluster Headache; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2004 |
[Triptans in migraine: a comparative review of pharmacology, pharmacokinetics].
Topics: Animals; Biological Availability; Cardiovascular System; Dose-Response Relationship, Drug; Humans; Indoles; Migraine Disorders; Oxazolidinones; Pyrrolidines; Receptor, Serotonin, 5-HT1D; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2004 |
[Triptans in migraine: from clinical view].
Topics: Drug Administration Schedule; Humans; Indoles; Migraine Disorders; Oxazolidinones; Pyrrolidines; Receptor, Serotonin, 5-HT1D; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2004 |
[Meta-analysis of triptan treatment in migraine].
Topics: Carbazoles; Evidence-Based Medicine; Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Receptor, Serotonin, 5-HT1D; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2004 |
[Side effects of triptans].
Topics: Central Nervous System; Dose-Response Relationship, Drug; Humans; Indoles; Migraine Disorders; Nausea; Oxazolidinones; Pyrrolidines; Receptor, Serotonin, 5-HT1D; Serotonin Receptor Agonists; Sleep Stages; Sumatriptan; Triazoles; Tryptamines; Vomiting | 2004 |
Migraine headache.
Topics: Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Diclofenac; Drug Therapy, Combination; Ergotamine; Humans; Ibuprofen; Indoles; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Oxazolidinones; Piperidines; Pyrrolidines; Salicylates; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2003 |
Migraine headache.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ergotamine; Humans; Ibuprofen; Indoles; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Oxazolidinones; Piperidines; Pyrrolidines; Salicylates; Sumatriptan; Triazoles; Tryptamines | 2004 |
Zolmitriptan (Zomig).
Topics: Clinical Trials as Topic; Dose-Response Relationship, Drug; Headache; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2004 |
Intranasal zolmitriptan.
Topics: Administration, Intranasal; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2005 |
The treatment of pediatric migraine.
Topics: Adrenergic beta-Antagonists; Anticonvulsants; Antidepressive Agents; Antiemetics; Biofeedback, Psychology; Calcium Channel Blockers; Child; Complementary Therapies; Contraindications; Cyproheptadine; Diet; Ergot Alkaloids; Humans; Migraine Disorders; Migraine without Aura; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2005 |
Part III: the convenience of, and patient preference for, zolmitriptan orally disintegrating tablet.
Topics: Chemistry, Pharmaceutical; Humans; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Serotonin Receptor Agonists; Tablets; Therapeutic Equivalency; Tryptamines | 2005 |
Zolmitriptan intranasal: a review of the pharmacokinetics and clinical efficacy.
Topics: Administration, Intranasal; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tissue Distribution; Tryptamines | 2006 |
Myocardial infarction after taking zolmitriptan.
Topics: Aged; Coronary Artery Disease; Female; Humans; Migraine Disorders; Myocardial Infarction; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2005 |
Acute treatment of paediatric migraine: a meta-analysis of efficacy.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Dihydroergotamine; Drug Evaluation; Humans; Ibuprofen; Migraine Disorders; Oxazolidinones; Placebos; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2008 |
Clinical pharmacology of the serotonin receptor agonist, zolmitriptan.
Topics: Clinical Trials as Topic; Humans; Migraine Disorders; Models, Biological; Molecular Structure; Oxazolidinones; Pharmacology, Clinical; Serotonin; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2007 |
Meta-analysis of the efficacy and safety of zolmitriptan in the acute treatment of migraine.
Topics: Adolescent; Adult; Age Factors; Aged; Databases, Factual; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Tryptamines | 2008 |
The clinical effectiveness of 311C90 in the acute treatment of migraine.
Topics: Double-Blind Method; Humans; Migraine Disorders; Multicenter Studies as Topic; Oxazoles; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Time Factors; Treatment Outcome; Tryptamines | 1996 |
Clinical safety of 311C90: aggregated data from patients and volunteers to date.
Topics: Adult; Aged; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Reference Values; Serotonin Receptor Agonists; Tryptamines | 1996 |
Inhibition of the trigemino-vascular system with 5-HT1D agonist drugs: selectively targeting additional sites of action.
Topics: Administration, Oral; Biological Availability; Cerebrovascular Circulation; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Trigeminal Nerve; Tryptamines | 1996 |
Emerging preclinical and clinical profile of 311C90: a poster review and discussion.
Topics: Animals; Central Nervous System; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Quality of Life; Serotonin Receptor Agonists; Tryptamines | 1996 |
Increasing the options for effective migraine management.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Ergotamine; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Quality of Life; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1997 |
311C90: increasing the options for therapy with effective acute antimigraine 5HT1B/1D receptor agonists.
Topics: Headache; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1997 |
Zolmitriptan. Introduction.
Topics: Drug Interactions; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 1997 |
Pre-clinical pharmacology of zolmitriptan (Zomig; formerly 311C90), a centrally and peripherally acting 5HT1B/1D agonist for migraine.
Topics: Administration, Oral; Animals; Biological Availability; Drug Evaluation, Preclinical; Hemodynamics; Injections, Intravenous; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1997 |
Potential drug interactions with the novel antimigraine compound zolmitriptan (Zomig, 311C90).
Topics: Acetaminophen; Adolescent; Adult; Drug Interactions; Drug Therapy, Combination; Ergotamine; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Tryptamines | 1997 |
Clinical applications of zolmitriptan (Zomig, 311C90).
Topics: Acute Disease; Disabled Persons; Dose-Response Relationship, Drug; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Tryptamines | 1997 |
[Mechanism of action of zolmitriptan].
Topics: Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1998 |
[Clinical efficacy of zolmitriptan in migraine].
Topics: Adolescent; Adult; Aged; Humans; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1998 |
[Safety profile of 311C90 (zolmitriptan)].
Topics: Dose-Response Relationship, Drug; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1998 |
Profiles of 5-HT 1B/1D agonists in acute migraine with special reference to second generation agents.
Topics: Acute Disease; Animals; Clinical Trials as Topic; Coronary Circulation; Coronary Vasospasm; Drug Design; Drug Interactions; Humans; Inactivation, Metabolic; Indoles; Meninges; Migraine Disorders; Molecular Structure; Nociceptors; Oxazoles; Oxazolidinones; Piperidines; Propranolol; Pyrrolidines; Randomized Controlled Trials as Topic; Rats; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Recurrence; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines; Vasoconstrictor Agents | 1999 |
Zolmitriptan: a review of its use in migraine.
Topics: Age Factors; Clinical Trials as Topic; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Time Factors; Tryptamines | 1999 |
Acute management of migraine: triptans and beyond.
Topics: Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
[Zolmitriptan].
Topics: Drug Costs; Drug Interactions; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Patient Selection; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 1999 |
The scientific basis of medication choice in symptomatic migraine treatment.
Topics: Acute Disease; Choice Behavior; Dose-Response Relationship, Drug; Humans; Indoles; Migraine Disorders; Models, Biological; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Severity of Illness Index; Sumatriptan; Triazoles; Tryptamines | 1999 |
Newer intranasal migraine medications.
Topics: Administration, Intranasal; Administration, Oral; Analgesics, Non-Narcotic; Clinical Trials as Topic; Dihydroergotamine; Half-Life; Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Recurrence; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2000 |
Current and emerging second-generation triptans in acute migraine therapy: a comparative review.
Topics: Acute Disease; Carbazoles; Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Pyrrolidines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Triazoles; Tryptamines | 2000 |
[Emergency treatment of migraine attacks with particular reference to agonists of 5-HT1B/1D receptor].
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Emergency Treatment; Ergotamine; Humans; Migraine Disorders; Nausea; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
New abortive agents for the treatment of migraine.
Topics: Clinical Trials as Topic; Female; Humans; Indoles; Male; Migraine Disorders; Oxazolidinones; Piperidines; Prognosis; Recurrence; Serotonin Receptor Agonists; Severity of Illness Index; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2001 |
[Current topics: expectation for new triptans].
Topics: Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2001 |
Establishing a standard of speed for assessing the efficacy of the serotonin(1B/1D) agonists (triptans).
Topics: Analgesics, Non-Narcotic; Carbazoles; Clinical Trials as Topic; Humans; Indoles; Migraine Disorders; Oxazolidinones; Pain Measurement; Patient Satisfaction; Piperidines; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Treatment Outcome; Triazoles; Tryptamines | 2001 |
Have the triptans fulfilled their promise?
Topics: Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2001 |
What matters is not the differences between triptans, but the differences between patients.
Topics: Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2001 |
Comparison of rizatriptan and other triptans on stringent measures of efficacy.
Topics: Administration, Oral; Humans; Indoles; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Piperidines; Randomized Controlled Trials as Topic; Retrospective Studies; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2001 |
Acute treatment of migraine and the role of triptans.
Topics: Acute Disease; Blood Flow Velocity; Carbazoles; Clinical Trials as Topic; Drug Administration Routes; Female; Humans; Indoles; Male; Menstruation; Migraine Disorders; Oxazolidinones; Piperidines; Practice Guidelines as Topic; Pyrrolidines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines; Vasoconstriction; Vasoconstrictor Agents | 2001 |
Review of zolmitriptan and its clinical applications in migraine.
Topics: Administration, Oral; Dose-Response Relationship, Drug; Drug Interactions; Humans; Migraine Disorders; Oxazolidinones; Randomized Controlled Trials as Topic; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 2002 |
73 trial(s) available for zolmitriptan and Migraine Disorders
| Article | Year |
|---|---|
A multicenter, randomized, double-blind, placebo-controlled, crossover trial to evaluate the efficacy and safety of zolmitriptan nasal spray for the acute treatment of migraine in patients aged 6 to 11 years, with an open-label extension.
Topics: Administration, Intranasal; Adult; Child; Cross-Over Studies; Double-Blind Method; Humans; Migraine Disorders; Nasal Sprays; Serotonin 5-HT1 Receptor Agonists; Treatment Outcome; Tryptamines | 2022 |
Development of a novel zolmitriptan intracutaneous microneedle system (Qtrypta™) for the acute treatment of migraine.
Topics: Double-Blind Method; Humans; Migraine Disorders; Oxazolidinones; Treatment Outcome; Tryptamines | 2020 |
Rapid systemic delivery of zolmitriptan using an adhesive dermally applied microarray.
Topics: Administration, Cutaneous; Adult; Cross-Over Studies; Drug Delivery Systems; Female; Humans; Male; Migraine Disorders; Oxazolidinones; Pain Management; Skin Physiological Phenomena; Tryptamines | 2017 |
Randomized, double-blind, placebo-controlled, parallel-group, multi-center study of the safety and efficacy of ADAM zolmitriptan for the acute treatment of migraine.
Topics: Administration, Cutaneous; Adult; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Transdermal Patch; Treatment Outcome; Tryptamines | 2018 |
Use of Most Bothersome Symptom as a Coprimary Endpoint in Migraine Clinical Trials: A Post-Hoc Analysis of the Pivotal ZOTRIP Randomized, Controlled Trial.
Topics: Adult; Biomarkers; Double-Blind Method; Humans; Hyperacusis; Injections, Intradermal; Migraine Disorders; Nausea; Outcome Assessment, Health Care; Oxazolidinones; Photophobia; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2018 |
Efficacy of ADAM Zolmitriptan for the Acute Treatment of Difficult-to-Treat Migraine Headaches.
Topics: Adult; Double-Blind Method; Female; Humans; Injections, Intradermal; Male; Middle Aged; Migraine Disorders; Nausea; Outcome Assessment, Health Care; Oxazolidinones; Pain Measurement; Serotonin 5-HT1 Receptor Agonists; Time Factors; Time-to-Treatment; Tryptamines | 2019 |
Zolmitriptan inhibits neurogenic inflammation and pain during electrical stimulation in human skin.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Electric Stimulation; Female; Humans; Male; Migraine Disorders; Neurogenic Inflammation; Neurons, Afferent; Nociceptors; Oxazolidinones; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Serotonin Receptor Agonists; Skin; Tryptamines; Young Adult | 2015 |
Theory-based analysis of clinical efficacy of triptans using receptor occupancy.
Topics: Humans; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Serotonin 5-HT1 Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2014 |
Oral zolmitriptan in the short-term prevention of menstrual migraine: a randomized, placebo-controlled study.
Topics: Administration, Oral; Adult; Double-Blind Method; Female; Humans; Menstruation Disturbances; Middle Aged; Migraine Disorders; Oxazolidinones; Retrospective Studies; Serotonin Receptor Agonists; Time Factors; Tryptamines | 2008 |
Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial.
Topics: Adult; Azepines; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Imidazoles; Male; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Severity of Illness Index; Tryptamines | 2008 |
Nitroglycerin provocation in normal subjects is not a useful human migraine model?
Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Studies; Double-Blind Method; Female; Humans; Infusions, Intravenous; Male; Migraine Disorders; Models, Biological; Nitroglycerin; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines; Vasodilator Agents; Young Adult | 2010 |
Frovatriptan versus zolmitriptan for the acute treatment of migraine: a double-blind, randomized, multicenter, Italian study.
Topics: Adolescent; Adult; Aged; Carbazoles; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Pain Measurement; Patient Satisfaction; Patient Selection; Serotonin Receptor Agonists; Surveys and Questionnaires; Treatment Outcome; Tryptamines | 2010 |
Sustained pain freedom and no adverse events as an endpoint in clinical trials of acute migraine treatments: application to patient-level data from a trial of the CGRP receptor antagonist, telcagepant, and zolmitriptan.
Topics: Adult; Analgesics; Azepines; Calcitonin Gene-Related Peptide Receptor Antagonists; Double-Blind Method; Female; Humans; Imidazoles; Male; Migraine Disorders; Oxazolidinones; Pain; Research Design; Serotonin 5-HT1 Receptor Antagonists; Tryptamines | 2011 |
Antimigraine efficacy of telcagepant based on patient's historical triptan response.
Topics: Adult; Azepines; Calcitonin Gene-Related Peptide Receptor Antagonists; Double-Blind Method; Female; Humans; Imidazoles; Male; Migraine Disorders; Oxazolidinones; Pain; Surveys and Questionnaires; Tryptamines | 2011 |
Efficacy of frovatriptan in the acute treatment of menstrually related migraine: analysis of a double-blind, randomized, multicenter, Italian, comparative study versus zolmitriptan.
Topics: Adult; Analgesics; Carbazoles; Cross-Over Studies; Double-Blind Method; Female; Humans; Italy; Migraine Disorders; Oxazolidinones; Premenstrual Syndrome; Tryptamines | 2011 |
Zolmitriptan is effective and well tolerated in Japanese patients with migraine: a dose-response study.
Topics: Adult; Cultural Characteristics; Dose-Response Relationship, Drug; Female; Humans; Hyperacusis; Japan; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Photophobia; Recurrence; Safety; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines; Vomiting | 2002 |
Zolmitriptan for treatment of migrainous vertigo: a pilot randomized placebo-controlled trial.
Topics: Administration, Oral; Adult; Aged; Cross-Over Studies; Double-Blind Method; Humans; Middle Aged; Migraine Disorders; Oxazolidinones; Treatment Outcome; Tryptamines; Vertigo | 2003 |
[Zolmitriptan as fast-melt tablet in the acute treatment of patients with migraine attacks: the ZORO study].
Topics: Adolescent; Adult; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Pain Measurement; Prospective Studies; Recurrence; Serotonin Receptor Agonists; Tablets; Time Factors; Tryptamines | 2003 |
Speed of onset and efficacy of zolmitriptan nasal spray in the acute treatment of migraine: a randomised, double-blind, placebo-controlled, dose-ranging study versus zolmitriptan tablet.
Topics: Administration, Intranasal; Administration, Oral; Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Time Factors; Tryptamines | 2003 |
Tolerability and consistency of effect of zolmitriptan nasal spray in a long-term migraine treatment trial.
Topics: Administration, Intranasal; Adolescent; Adult; Aged; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Serotonin Receptor Agonists; Time Factors; Treatment Outcome; Tryptamines | 2003 |
Patients with migraine prefer zolmitriptan orally disintegrating tablet to sumatriptan conventional oral tablet.
Topics: Administration, Oral; Adolescent; Adult; Aged; Cross-Over Studies; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Serotonin Receptor Agonists; Sumatriptan; Tablets; Treatment Outcome; Tryptamines | 2003 |
Zolmitriptan nasal spray: advances in migraine treatment.
Topics: Absorption; Administration, Intranasal; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Migraine Disorders; Nasal Decongestants; Oxazolidinones; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines; Vasoconstrictor Agents | 2003 |
Efficacy and tolerability of oral zolmitriptan in menstrually associated migraine: a randomized, prospective, parallel-group, double-blind, placebo-controlled study.
Topics: Adolescent; Adult; Double-Blind Method; Female; Follow-Up Studies; Humans; Menstruation; Middle Aged; Migraine Disorders; Oxazolidinones; Prospective Studies; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2004 |
Comparative efficacy of eletriptan and zolmitriptan in the acute treatment of migraine.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Indoles; Linear Models; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Pyrrolidines; Tryptamines | 2003 |
Benefits of treating highly disabled migraine patients with zolmitriptan while pain is mild.
Topics: Activities of Daily Living; Adolescent; Adult; Aged; Confidence Intervals; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Migraine Disorders; Odds Ratio; Oxazolidinones; Pain; Prospective Studies; Time Factors; Tryptamines | 2004 |
Migraine treatment strategies: the global Migraine And Zolmitriptan Evaluation (MAZE) survey--phase IV.
Topics: Adult; Drug Prescriptions; Female; Humans; Male; Middle Aged; Migraine Disorders; Nonprescription Drugs; Oxazolidinones; Patient Satisfaction; Patients; Serotonin Receptor Agonists; Surveys and Questionnaires; Tryptamines; United Kingdom | 2004 |
Zolmitriptan 5 mg nasal spray: efficacy and onset of action in the acute treatment of migraine--results from phase 1 of the REALIZE Study.
Topics: Acute Disease; Administration, Intranasal; Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2005 |
Zolmitriptan nasal spray exhibits good long-term safety and tolerability in migraine: results of the INDEX trial.
Topics: Administration, Intranasal; Adolescent; Adult; Aged; Humans; Middle Aged; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2005 |
Speed of onset, efficacy and tolerability of zolmitriptan nasal spray in the acute treatment of migraine: a randomised, double-blind, placebo-controlled study.
Topics: Administration, Intranasal; Adolescent; Adult; Aged; Double-Blind Method; Drug Tolerance; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Pain Measurement; Reaction Time; Recurrence; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Treatment Outcome; Tryptamines | 2005 |
Pain-free rates with zolmitriptan 2.5 mg ODT in the acute treatment of migraine: results of a large double-blind placebo- controlled trial.
Topics: Acute Disease; Administration, Oral; Adult; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Pain; Placebos; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2005 |
Multiple attack study on the available triptans in Italy versus placebo.
Topics: Adult; Female; Humans; Indoles; Italy; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2005 |
Treatment satisfaction with zolmitriptan nasal spray for migraine in a real life setting: results from phase two of the REALIZE study.
Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Drug Administration Routes; Female; Humans; Male; Middle Aged; Migraine Disorders; Nasal Cavity; Oxazolidinones; Pain Measurement; Patient Satisfaction; Serotonin Receptor Agonists; Time Factors; Treatment Outcome; Tryptamines | 2005 |
Zolmitriptan oral tablet in migraine treatment: high placebo responses in adolescents.
Topics: Adolescent; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Migraine Disorders; Oxazolidinones; Pain Measurement; Placebo Effect; Serotonin Receptor Agonists; Tryptamines | 2006 |
Efficacy and tolerability of almotriptan versus zolmitriptan for the acute treatment of menstrual migraine.
Topics: Adult; Double-Blind Method; Dysmenorrhea; Female; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Time Factors; Treatment Outcome; Tryptamines | 2006 |
Treatment of childhood migraine attacks with oral zolmitriptan and ibuprofen.
Topics: Administration, Oral; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Child; Double-Blind Method; Female; Humans; Ibuprofen; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2006 |
[Symptomatic treatment of migraine with zolmitriptan: experience with 82 patients].
Topics: Administration, Intranasal; Adolescent; Adult; Aged; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2006 |
Efficacy and tolerability of zolmitriptan oral tablet in the acute treatment of menstrual migraine.
Topics: Acute Disease; Administration, Oral; Adult; Chest Pain; Dizziness; Double-Blind Method; Female; Humans; Menstruation Disturbances; Middle Aged; Migraine Disorders; Nausea; Oxazolidinones; Paresthesia; Patient Dropouts; Self Administration; Serotonin Receptor Agonists; Tablets; Treatment Outcome; Tryptamines | 2006 |
Almotriptan and zolmitriptan in the acute treatment of migraine.
Topics: Acute Disease; Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2007 |
Efficacy of zolmitriptan nasal spray in adolescent migraine.
Topics: Administration, Intranasal; Adolescent; Child; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Migraine Disorders; Oxazolidinones; Single-Blind Method; Time Factors; Tryptamines | 2007 |
Patient preference for triptan formulations: a prospective study with zolmitriptan.
Topics: Adolescent; Adult; Aged; Chemistry, Pharmaceutical; Cross-Over Studies; Disability Evaluation; Female; Humans; Longitudinal Studies; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Serotonin Receptor Agonists; Severity of Illness Index; Tryptamines | 2007 |
311C90, a new central and peripherally acting 5-HT1D receptor agonist in the acute oral treatment of migraine: a double-blind, placebo-controlled, dose-range finding study.
Topics: Administration, Oral; Adolescent; Adult; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Pain Measurement; Placebos; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1996 |
Evaluation of the long-term safety and efficacy of 311C90 in the treatment of migraine.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Child; Drug Administration Schedule; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Time Factors; Treatment Outcome; Tryptamines | 1996 |
Can oral 311C90, a novel 5-HT1D agonist, prevent migraine headache when taken during an aura?
Topics: Administration, Oral; Adult; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines; United Kingdom | 1996 |
The tolerability and pharmacokinetics of the novel antimigraine compound 311C90 in healthy male volunteers.
Topics: Administration, Oral; Adolescent; Adult; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Placebos; Reference Values; Serotonin Receptor Agonists; Tryptamines | 1996 |
311C90: long-term efficacy and tolerability profile for the acute treatment of migraine. International 311C90 Long-Term Study Group.
Topics: Adolescent; Adult; Aged; Child; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Research Design; Serotonin Receptor Agonists; Time Factors; Tryptamines | 1997 |
The pharmacokinetics and effects on blood pressure of multiple doses of the novel anti-migraine drug zolmitriptan (311C90) in healthy volunteers.
Topics: Administration, Oral; Adult; Analysis of Variance; Blood Pressure; Cross-Over Studies; Double-Blind Method; Female; Heart Rate; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1997 |
[Zolmitriptan: new perspectives in migraine therapy. Satellite symposium of the 11th Migraine Trust International Symposium, London, 10 September 1996].
Topics: Blood-Brain Barrier; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Sumatriptan; Tryptamines | 1997 |
The absolute bioavailability and metabolic disposition of the novel antimigraine compound zolmitriptan (311C90).
Topics: Absorption; Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cross-Over Studies; Feces; Female; Half-Life; Humans; Indoleacetic Acids; Infusions, Intravenous; Male; Mass Spectrometry; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sex Factors; Tryptamines | 1997 |
Clinical efficacy and tolerability of 2.5 mg zolmitriptan for the acute treatment of migraine. The 042 Clinical Trial Study Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1997 |
Optimizing the dose of zolmitriptan (Zomig, 311C90) for the acute treatment of migraine. A multicenter, double-blind, placebo-controlled, dose range-finding study. The 017 Clinical Trial Study Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Tryptamines | 1997 |
Zolmitriptan (Zomig, 311C90), a novel dual central and peripheral 5HT1B/1D agonist: an overview of efficacy.
Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Female; Humans; Menstruation; Middle Aged; Migraine Disorders; Nausea; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines | 1997 |
No need to adjust the dose of 311C90 (zolmitriptan), a novel anti-migraine treatment, in patients with renal failure not requiring dialysis.
Topics: Adult; Aged; Area Under Curve; Blood Pressure; Electrocardiography; Female; Half-Life; Humans; Kidney Failure, Chronic; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Renal Dialysis; Serotonin Receptor Agonists; Tryptamines | 1997 |
Intensity dependence of the cortical auditory evoked potentials as a surrogate marker of central nervous system serotonin transmission in man: demonstration of a central effect for the 5HT1B/1D agonist zolmitriptan (311C90, Zomig).
Topics: Adult; Cerebral Cortex; Dose-Response Relationship, Drug; Double-Blind Method; Evoked Potentials, Auditory; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Synaptic Transmission; Tryptamines | 1997 |
The novel anti-migraine compound zolmitriptan (Zomig 311C90) has no clinically significant interactions with paracetamol or metoclopramide.
Topics: Acetaminophen; Adult; Blood Pressure; Drug Interactions; Female; Humans; Male; Metoclopramide; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1997 |
The long-term tolerability and efficacy of oral zolmitriptan (Zomig, 311C90) in the acute treatment of migraine. An international study. The International 311C90 Long-term Study Group.
Topics: Adult; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Tryptamines | 1998 |
Effects of zolmitriptan (Zomig) on central serotonergic neurotransmission as assessed by active oddball auditory event-related potentials in volunteers without migraine.
Topics: Acoustic Stimulation; Adult; Double-Blind Method; Electroencephalography; Evoked Potentials, Auditory; Female; Humans; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Reference Values; Serotonin Receptor Agonists; Tryptamines | 1999 |
A comparison of the pharmacokinetics and tolerability of the novel antimigraine compound zolmitriptan in adolescents and adults.
Topics: Adolescent; Adult; Aged; Aging; Area Under Curve; Biotransformation; Child; Female; Half-Life; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1999 |
Unbalanced randomization influences placebo response: scientific versus ethical issues around the use of placebo in migraine trials.
Topics: Double-Blind Method; Ethics, Medical; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Placebos; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines | 1999 |
A long-term study to maximise migraine relief with zolmitriptan.
Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Tablets; Time Factors; Tryptamines | 1999 |
Zolmitriptan provides consistent migraine relief when used in the long-term.
Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Time Factors; Tryptamines | 1999 |
Zolmitriptan is effective for the treatment of persistent and recurrent migraine headache.
Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Time Factors; Tryptamines | 1999 |
[Oral zolmitriptan (Zomig) in the treatment of migraine crisis].
Topics: Administration, Oral; Adolescent; Adult; Humans; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2000 |
A comparative trial of zolmitriptan and sumatriptan for the acute oral treatment of migraine.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Patient Satisfaction; Recurrence; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Treatment Outcome; Tryptamines | 2000 |
Comparison of the efficacy of zolmitriptan and sumatriptan: issues in migraine trial design.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Research Design; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines | 2000 |
Treatment of nonresponders to oral sumatriptan with zolmitriptan and rizatriptan: a comparative open trial.
Topics: Administration, Oral; Cross-Over Studies; Drug Resistance; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Retreatment; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents | 2000 |
Comparison of rizatriptan 10 mg vs. zolmitriptan 2.5 mg in the acute treatment of migraine. Rizatriptan-Zolmitriptan Study Group.
Topics: Adult; Disability Evaluation; Double-Blind Method; Female; Humans; Male; Migraine Disorders; Oxazolidinones; Quality of Life; Recurrence; Retreatment; Serotonin Receptor Agonists; Time Factors; Triazoles; Tryptamines | 2000 |
Vascular effects of 5-HT1B/1D-receptor agonists in patients with migraine headaches.
Topics: Adult; Analysis of Variance; Blood Flow Velocity; Blood Pressure; Brachial Artery; Carotid Artery, Common; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Temporal Arteries; Triazoles; Tryptamines; Ultrasonography; Vascular Resistance; Vasoconstrictor Agents; Vasodilation | 2000 |
Zolmitriptan provides effective migraine relief in adolescents.
Topics: Acute Disease; Adolescent; Child; Dose-Response Relationship, Drug; Female; Humans; Male; Migraine Disorders; Oxazolidinones; Pain Measurement; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2000 |
Zolmitriptan versus sumatriptan for the acute oral treatment of migraine: a randomized, double-blind, international study.
Topics: Administration, Oral; Adult; Double-Blind Method; Female; Humans; International Cooperation; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Severity of Illness Index; Sumatriptan; Treatment Outcome; Tryptamines | 2001 |
Zolmitriptan versus a combination of acetylsalicylic acid and metoclopramide in the acute oral treatment of migraine: a double-blind, randomised, three-attack study.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aspirin; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Metoclopramide; Middle Aged; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2002 |
Cost-effectiveness analysis of stratified versus stepped care strategies for acute treatment of migraine: The Disability in Strategies for Care (DISC) Study.
Topics: Cost-Benefit Analysis; Disability Evaluation; Drug Costs; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2002 |
Acute migraine headache: possible sensitization of neurons in the spinal trigeminal nucleus?
Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Aspirin; Blinking; Electroencephalography; Electrophysiology; Female; Humans; Male; Middle Aged; Migraine Disorders; Nerve Fibers; Neurons; Nociceptors; Oxazolidinones; Trigeminal Nucleus, Spinal; Tryptamines | 2002 |
Zolmitriptan orally disintegrating tablet is effective in the acute treatment of migraine.
Topics: Administration, Oral; Adult; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Palliative Care; Patient Satisfaction; Recurrence; Retreatment; Serotonin Receptor Agonists; Solubility; Tryptamines | 2002 |
108 other study(ies) available for zolmitriptan and Migraine Disorders
| Article | Year |
|---|---|
Computer-aided design and synthesis of 5-substituted tryptamines and their pharmacology at the 5-HT1D receptor: discovery of compounds with potential anti-migraine properties.
Topics: Animals; Aorta; Computer-Aided Design; Drug Design; Haplorhini; In Vitro Techniques; Migraine Disorders; Models, Chemical; Rabbits; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1D; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Saphenous Vein; Serotonin Receptor Agonists; Structure-Activity Relationship; Tryptamines | 1995 |
Discovery of 4-[3-(trans-3-dimethylaminocyclobutyl)-1H-indol-5-ylmethyl]-(4S)-oxazolidin-2-one (4991W93), a 5HT(1B/1D) receptor partial agonist and a potent inhibitor of electrically induced plasma extravasation.
Topics: Administration, Oral; Animals; Binding, Competitive; Biological Availability; Brain; Capillary Permeability; Cattle; CHO Cells; Cricetinae; Ear; Electric Stimulation; Guinea Pigs; Humans; In Vitro Techniques; Indoles; Male; Migraine Disorders; Models, Molecular; Oxazoles; Rabbits; Rats; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Regional Blood Flow; Serotonin Receptor Agonists; Serum Albumin, Bovine; Structure-Activity Relationship; Trigeminal Ganglion; Vasoconstrictor Agents | 2001 |
Evaluation of Brain Targeting Potential of Zolmitriptan Mucoadhesive Nanoparticles for Intranasal Drug Delivery.
Topics: Administration, Intranasal; Animals; Brain; Male; Mice; Migraine Disorders; Nanoparticles; Oxazolidinones; Rats; Rats, Wistar; Tryptamines | 2022 |
Pharmacokinetic study and brain tissue analysis of Zolmitriptan loaded chitosan nanoparticles in rats by LC-MS method.
Topics: Administration, Intranasal; Animals; Brain; Chitosan; Chromatography, Liquid; Disease Models, Animal; Male; Migraine Disorders; Nanoparticles; Oxazolidinones; Particle Size; Rats; Rats, Wistar; Tandem Mass Spectrometry; Tryptamines | 2020 |
Could inhaled drug formulations be the future of acute migraine treatment?
Topics: Administration, Inhalation; Administration, Intranasal; Blood-Brain Barrier; Dihydroergotamine; Dopamine Agonists; Humans; Metered Dose Inhalers; Migraine Disorders; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2019 |
Assessment Of Spanlastic Vesicles Of Zolmitriptan For Treating Migraine In Rats.
Topics: Administration, Intranasal; Animals; Injections, Intraperitoneal; Male; Migraine Disorders; Nitroglycerin; Oxazolidinones; Rats; Rats, Wistar; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2019 |
Transfer of triptans into human breast milk and estimation of infant drug exposure through breastfeeding.
Topics: Adult; Breast Feeding; Female; Humans; Infant; Infant, Newborn; Migraine Disorders; Milk, Human; Oxazolidinones; Piperidines; Pyrrolidines; Triazoles; Tryptamines | 2021 |
Long term safety, tolerability, and efficacy of intracutaneous zolmitriptan (M207) in the acute treatment of migraine.
Topics: Double-Blind Method; Humans; Migraine Disorders; Oxazolidinones; Treatment Outcome; Tryptamines | 2021 |
One should avoid retro-orbital pharmacokinetic sample collections for intranasal dosing in rats: Illustration of spurious pharmacokinetics generated for anti-migraine drugs zolmitriptan and eletriptan.
Topics: Administration, Intranasal; Administration, Oral; Animals; Area Under Curve; Biological Availability; Blood Specimen Collection; Chromatography, High Pressure Liquid; Humans; Male; Migraine Disorders; Oxazolidinones; Pyrrolidines; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Tryptamines | 2017 |
Population Pharmacokinetic Analysis of Zolmitriptan and Its Metabolite in Adults and Adolescents to Support Dose Selection in Children With Migraine.
Topics: Administration, Intranasal; Adolescent; Adult; Body Weight; Child; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Migraine Disorders; Models, Biological; Oxazoles; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Tryptamines; Young Adult | 2017 |
Brain targeting efficiency of antimigrain drug loaded mucoadhesive intranasal nanoemulsion.
Topics: Administration, Intranasal; Animals; Brain; Chemistry, Pharmaceutical; Mice; Migraine Disorders; Nasal Mucosa; Oxazolidinones; Tryptamines | 2017 |
Drug-induced Myopia and Bilateral Angle Closure Secondary to Zolmitriptan.
Topics: Adult; Female; Glaucoma, Angle-Closure; Humans; Migraine Disorders; Myopia; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2017 |
Development of zolmitriptan transfersomes by Box-Behnken design for nasal delivery: in vitro and in vivo evaluation.
Topics: Administration, Intranasal; Animals; Biological Availability; Chemistry, Pharmaceutical; Drug Delivery Systems; Drug Liberation; Lecithins; Male; Migraine Disorders; Oxazolidinones; Particle Size; Polysorbates; Rats; Rats, Wistar; Solubility; Surface-Active Agents; Tryptamines | 2018 |
Pharmacokinetics and Skin Tolerability of Intracutaneous Zolmitriptan Delivery in Swine Using Adhesive Dermally Applied Microarray.
Topics: Administration, Cutaneous; Animals; Biological Availability; Drug Delivery Systems; Equipment Design; Female; Migraine Disorders; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Skin; Skin Absorption; Swine; Transdermal Patch; Tryptamines | 2018 |
Cost-Effectiveness of Reclassifying Triptans in Australia: Application of an Economic Evaluation Approach to Regulatory Decisions.
Topics: Australia; Cost-Benefit Analysis; Drug and Narcotic Control; General Practitioners; Humans; Migraine Disorders; Nonprescription Drugs; Oxazolidinones; Pharmacists; Prescription Drugs; Serotonin 5-HT1 Receptor Agonists; Sumatriptan; Tryptamines | 2019 |
Frovatriptan vs. other triptans for the acute treatment of oral contraceptive-induced menstrual migraine: pooled analysis of three double-blind, randomized, crossover, multicenter studies.
Topics: Carbazoles; Contraceptives, Oral, Hormonal; Cross-Over Studies; Double-Blind Method; Female; Humans; Menstruation; Migraine Disorders; Multicenter Studies as Topic; Oxazolidinones; Premenstrual Syndrome; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Triazoles; Tryptamines | 2013 |
Zolmitriptan oxalate and zolmitriptan camphorsulfonate: the first structural study of salt complexes of the antimigraine drug zolmitriptan.
Topics: Crystallography, X-Ray; Migraine Disorders; Molecular Structure; Oxalates; Oxazolidinones; Salts; Tryptamines | 2013 |
Formulation and evaluation of chitosan-chondroitin sulphate based nasal inserts for zolmitriptan.
Topics: Administration, Intranasal; Brain; Chemistry, Pharmaceutical; Chitosan; Chondroitin Sulfates; Drug Delivery Systems; Humans; Microscopy, Electron, Scanning; Migraine Disorders; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2013 |
Duel-acting subcutaneous microemulsion formulation for improved migraine treatment with zolmitriptan and diclofenac: formulation and in vitro-in vivo characterization.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Emulsions; In Vitro Techniques; Male; Microscopy, Electron, Transmission; Migraine Disorders; Oxazolidinones; Rats; Rats, Wistar; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2014 |
Images of an occlusive arterial disease of lower extremity due to chronic intoxication by ergot alkaloid.
Topics: Arterial Occlusive Diseases; Clopidogrel; Drug Substitution; Female; Humans; Lower Extremity; Methysergide; Middle Aged; Migraine Disorders; Oxazolidinones; Platelet Aggregation Inhibitors; Predictive Value of Tests; Serotonin 5-HT1 Receptor Agonists; Ticlopidine; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Tryptamines; Vasoconstrictor Agents | 2014 |
Optimization of combinational intranasal drug delivery system for the management of migraine by using statistical design.
Topics: Adhesives; Administration, Intranasal; Animals; Disease Management; Drug Delivery Systems; Gels; Ketorolac; Migraine Disorders; Nasal Mucosa; Oxazolidinones; Sheep; Tryptamines | 2015 |
Development of zolmitriptan loaded PLGA/poloxamer nanoparticles for migraine using quality by design approach.
Topics: Animals; Brain; Calorimetry, Differential Scanning; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Drug Design; Drug Liberation; Lactic Acid; Male; Mice; Migraine Disorders; Nanoparticles; Oxazolidinones; Particle Size; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Serotonin 5-HT1 Receptor Agonists; Spectroscopy, Fourier Transform Infrared; Thermogravimetry; Tryptamines; X-Ray Diffraction | 2016 |
Trans-nasal zolmitriptan novasomes: in-vitro preparation, optimization and in-vivo evaluation of brain targeting efficiency.
Topics: Administration, Intranasal; Administration, Oral; Animals; Brain; Chemistry, Pharmaceutical; Drug Delivery Systems; Male; Mice; Migraine Disorders; Nasal Mucosa; Oxazolidinones; Particle Size; Surface-Active Agents; Tryptamines | 2016 |
CGRP-receptor antagonism in migraine treatment.
Topics: Animals; Azepines; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Cerebrovascular Circulation; Humans; Imidazoles; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2008 |
Migraine and telcagepant [corrected].
Topics: Dipeptides; Humans; Migraine Disorders; Oxazolidinones; Piperazines; Quality of Life; Quinazolines; Treatment Outcome; Tryptamines | 2009 |
Molecule of the month. Telcagepant.
Topics: Azepines; Calcitonin Gene-Related Peptide Receptor Antagonists; Humans; Imidazoles; Migraine Disorders; Oxazolidinones; Randomized Controlled Trials as Topic; Tryptamines | 2009 |
Rizatriptan. Comparative trial results.
Topics: Adolescent; Adult; Aged; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Time Factors; Treatment Outcome; Triazoles; Tryptamines; Vasoconstrictor Agents; Young Adult | 2000 |
Drug dependence associated with triptans and ergot derivatives: a case/non-case study.
Topics: Claviceps; Dihydroergotamine; Ergotamine; Humans; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Risk; Substance-Related Disorders; Sumatriptan; Tryptamines | 2010 |
Micellar nanocarriers: potential nose-to-brain delivery of zolmitriptan as novel migraine therapy.
Topics: Animals; Brain; Female; Humans; Male; Micelles; Migraine Disorders; Nanostructures; Oxazolidinones; Rats; Rats, Wistar; Serotonin Receptor Agonists; Tryptamines | 2010 |
Comparison of the vasoconstrictor effects of the calcitonin gene-related peptide receptor antagonist telcagepant (MK-0974) and zolmitriptan in human isolated coronary arteries.
Topics: Adult; Azepines; Calcitonin Gene-Related Peptide Receptor Antagonists; Coronary Vessels; Dose-Response Relationship, Drug; Humans; Imidazoles; In Vitro Techniques; Middle Aged; Migraine Disorders; Oxazolidinones; Tryptamines; Vasoconstriction; Vasodilation; Vasodilator Agents | 2010 |
Evolution of paediatric off-label use after new significant medicines become available for adults: a study on triptans in Finnish children 1994-2007.
Topics: Adolescent; Adult; Age Factors; Child; Drug Approval; Female; Finland; Humans; Male; Migraine Disorders; Off-Label Use; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Sumatriptan; Time Factors; Triazoles; Tryptamines; Young Adult | 2011 |
Zolmitriptan induced acute coronary syndrome: a unique case.
Topics: Acute Coronary Syndrome; Chest Pain; Electrocardiography; Humans; Male; Middle Aged; Migraine Disorders; Myocardial Infarction; Nitroglycerin; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Tryptamines; Vasodilator Agents | 2011 |
Fast relief from migraine attacks using fast-disintegrating sublingual zolmitriptan tablets.
Topics: Administration, Sublingual; Animals; Biological Availability; Female; Humans; Male; Migraine Disorders; Oxazolidinones; Rabbits; Serotonin 5-HT1 Receptor Agonists; Solubility; Tablets; Time Factors; Tryptamines | 2012 |
Clinical reasoning: a 62-year-old migraineur with a new kind of headache attacks.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Magnetic Resonance Angiography; Male; Migraine Disorders; Oxazolidinones; Serotonin 5-HT1 Receptor Agonists; Tryptamines | 2012 |
Pharmacokinetic evaluation of zolmitriptan for the treatment of migraines.
Topics: Cluster Headache; Drug Evaluation; Humans; Migraine Disorders; Oxazolidinones; Treatment Outcome; Tryptamines | 2012 |
[CME "Takotsubo cardiomyopathy].
Topics: Coronary Angiography; Coronary Vasospasm; Diagnosis, Differential; Female; Humans; Migraine Disorders; Myocardial Ischemia; Oxazolidinones; Patient Education as Topic; Risk Factors; Serotonin 5-HT1 Receptor Agonists; Stress, Psychological; Takotsubo Cardiomyopathy; Tryptamines | 2012 |
Influence of polymeric microcarriers on the in vivo intranasal uptake of an anti-migraine drug for brain targeting.
Topics: Adhesives; Administration, Intranasal; Administration, Intravenous; Animals; Area Under Curve; Brain; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Glutamic Acid; Hypromellose Derivatives; Migraine Disorders; Nasal Mucosa; Oxazolidinones; Permeability; Polymers; Powders; Swine; Tryptamines | 2013 |
Restoring migraine sufferers' ability to function normally: a comparison of rizatriptan and other triptans in randomized trials.
Topics: Administration, Oral; Adolescent; Adult; Aged; Female; Humans; Indoles; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Piperidines; Randomized Controlled Trials as Topic; Retrospective Studies; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2002 |
The antimigraine 5-HT 1B/1D receptor agonists, sumatriptan, zolmitriptan and dihydroergotamine, attenuate pain-related behaviour in a rat model of trigeminal neuropathic pain.
Topics: Animals; Dihydroergotamine; Disease Models, Animal; Male; Migraine Disorders; Oxazolidinones; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Trigeminal Nerve Diseases; Tryptamines | 2002 |
[Triptane. Zolmitriptan--fast and effective in migraine].
Topics: Drug Therapy, Combination; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2003 |
Migraine prevalence and treatment patterns: the global Migraine and Zolmitriptan Evaluation survey.
Topics: Acute Disease; Administration, Oral; Adult; Analgesics; Europe; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Prevalence; Serotonin Receptor Agonists; Surveys and Questionnaires; Tryptamines; United States | 2003 |
Abnormal habituation of 'nociceptive' blink reflex in migraine--evidence for increased excitability of trigeminal nociception.
Topics: Adult; Analysis of Variance; Aspirin; Blinking; Female; Follow-Up Studies; Habituation, Psychophysiologic; Humans; Lysine; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Pain Measurement; Trigeminal Nerve; Tryptamines | 2003 |
[Improved pharmacokinetics. Fast tryptan with sustained response].
Topics: Administration, Oral; Controlled Clinical Trials as Topic; Delayed-Action Preparations; Female; Headache; Humans; Indoles; Male; Migraine Disorders; Oxazolidinones; Piperidines; Placebos; Pyrrolidines; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Tryptamines | 2003 |
[Highly selective beginning. Associated symptoms and side effects in retrospect].
Topics: Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Pyrrolidines; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2003 |
Effects of acute or chronic administration of anti-migraine drugs sumatriptan and zolmitriptan on serotonin synthesis in the rat brain.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Infusions, Parenteral; Injections, Subcutaneous; Male; Metabolic Clearance Rate; Migraine Disorders; Oxazolidinones; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Sumatriptan; Tissue Distribution; Tryptamines | 2004 |
Defeating migraine pain with triptans: a race against the development of cutaneous allodynia.
Topics: Administration, Oral; Adolescent; Adult; Humans; Injections; Middle Aged; Migraine Disorders; Oxazolidinones; Pain; Pain Measurement; Prospective Studies; Serotonin Receptor Agonists; Skin; Sumatriptan; Time Factors; Triazoles; Tryptamines | 2004 |
Zolmitriptan (Zomig) nasal spray for migraine.
Topics: Administration, Intranasal; Contraindications; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2004 |
Managing migraines. New treatments focus on relieving pain fast--or heading off these headaches before they begin.
Topics: Administration, Intranasal; Botulinum Toxins, Type A; Fructose; Heart Septal Defects, Atrial; Humans; Migraine Disorders; Neuromuscular Agents; Neuroprotective Agents; Oxazolidinones; Serotonin Receptor Agonists; Sleep Bruxism; Topiramate; Tryptamines | 2004 |
Patients with migraine prefer zolmitriptan orally disintegrating tablet to sumatriptan conventional oral tablet.
Topics: Humans; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Serotonin Receptor Agonists; Sumatriptan; Tablets; Tryptamines | 2004 |
Fixed drug eruption of the penis due to zolmitriptan.
Topics: Adult; Drug Eruptions; Humans; Male; Migraine Disorders; Oxazolidinones; Penis; Serotonin Receptor Agonists; Tryptamines | 2004 |
[Unstable angina in relationship to intake of zolmitriptan].
Topics: Adult; Angina, Unstable; Electrocardiography; Female; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 2004 |
Impact of migraine on patients and their families: the Migraine And Zolmitriptan Evaluation (MAZE) survey--Phase III.
Topics: Absenteeism; Adult; Chronic Disease; Cost of Illness; Efficiency; Family Relations; Female; Health Care Surveys; Humans; Menstrual Cycle; Migraine Disorders; Oxazolidinones; Prevalence; Risk Factors; Serotonin Receptor Agonists; Sickness Impact Profile; Surveys and Questionnaires; Tryptamines | 2004 |
The therapeutic profile of zolmitriptan in clinical practice.
Topics: Adult; Female; Humans; Male; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2004 |
Correlation between lipophilicity and triptan outcomes.
Topics: Central Nervous System Diseases; Chemical Phenomena; Chemistry, Physical; Humans; Indoles; Migraine Disorders; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Statistics as Topic; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines | 2005 |
Part II: clinical efficacy and tolerability of zolmitriptan orally disintegrating tablet in the acute treatment of migraine.
Topics: Acute Disease; Humans; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tablets; Therapeutic Equivalency; Time Factors; Treatment Outcome; Tryptamines | 2005 |
Part IV: effects of zolmitriptan orally disintegrating tablet on migraine symptoms and ability to perform normal activities: a post-marketing surveillance study in Germany.
Topics: Activities of Daily Living; Administration, Oral; Adult; Female; Germany; Humans; Male; Migraine Disorders; Oxazolidinones; Product Surveillance, Postmarketing; Quality of Life; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2005 |
[Extrahepatic cholestasia during therapy with Zolmitriptan (AscoTop)].
Topics: Bile Ducts, Extrahepatic; Cholestasis, Extrahepatic; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Radionuclide Imaging; Serotonin Receptor Agonists; Tryptamines | 2005 |
Over-the-counter triptans--making the switch.
Topics: Drug and Narcotic Control; Drug Approval; Drug Interactions; Humans; Migraine Disorders; Nonprescription Drugs; Oxazolidinones; Pharmacies; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; United Kingdom | 2005 |
[Medical treatment of migraine attacks in the child].
Topics: Acetaminophen; Age Factors; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Child; Ergot Alkaloids; Humans; Ibuprofen; Life Style; Migraine Disorders; Oxazolidinones; Parents; Patient Education as Topic; Pediatrics; Piperidines; Pyrrolidines; Risk Factors; Serotonin Receptor Agonists; Sumatriptan; Taste Disorders; Triazoles; Tryptamines; Vasoconstrictor Agents | 2006 |
Renal infarction during the use of rizatriptan and zolmitriptan: two case reports.
Topics: Adult; Cluster Headache; Humans; Infarction; Kidney; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Tomography, X-Ray Computed; Triazoles; Tryptamines | 2006 |
Acute renal failure in a 17-year-old female with ALL receiving escalating intravenous methotrexate without leukovorin.
Topics: Acute Kidney Injury; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Infusions, Intravenous; Leucovorin; Methotrexate; Migraine Disorders; Oxazolidinones; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Serotonin Receptor Agonists; Tryptamines | 2007 |
Improved migraine management in primary care: results of a patient treatment experience study using zolmitriptan orally disintegrating tablet.
Topics: Administration, Oral; Adolescent; Adult; Aged; Humans; Middle Aged; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Serotonin Receptor Agonists; Tablets; Treatment Outcome; Tryptamines | 2006 |
Treatment of childhood migraine attacks with oral zolmitriptan and ibuprofen.
Topics: Analgesics, Non-Narcotic; Drug Combinations; Drug Costs; Humans; Ibuprofen; Migraine Disorders; Nonprescription Drugs; Oxazolidinones; Tryptamines | 2007 |
Renal ischaemic injuries during the use of zolmitriptan for treatment of migraines in a transplanted patient under tacrolimus therapy.
Topics: Adult; Female; Humans; Ischemia; Kidney Transplantation; Migraine Disorders; Oxazolidinones; Postoperative Complications; Serotonin Antagonists; Treatment Outcome; Tryptamines | 2007 |
The impact of migraine: a case study.
Topics: Acupuncture Therapy; Administration, Rectal; Adult; Caffeine; Combined Modality Therapy; Drug Combinations; Ergotamine; Fructose; Humans; Male; Manipulation, Chiropractic; Middle Aged; Migraine Disorders; Neuroprotective Agents; Oxazolidinones; Serotonin Receptor Agonists; Severity of Illness Index; Topiramate; Tryptamines; Vasoconstrictor Agents | 2007 |
Tactile-induced ultrasonic vocalization in the rat: a novel assay to assess anti-migraine therapies in vivo.
Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Drugs, Investigational; Inflammation Mediators; Injections, Intraventricular; Injections, Subcutaneous; Ketorolac; Lipopolysaccharides; Male; Meningitis; Migraine Disorders; Morphine; Nociceptors; Oxazolidinones; Pain Threshold; Rats; Rats, Sprague-Dawley; Touch; Trigeminal Nerve; Tryptamines; Vocalization, Animal | 2008 |
Extending therapeutic options? Prospects for the future.
Topics: Cerebrovascular Circulation; Forecasting; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Trigeminal Nerve; Tryptamines | 1996 |
311C90 (Zolmitriptan), a novel centrally and peripheral acting oral 5-hydroxytryptamine-1D agonist: a comparison of its absorption during a migraine attack and in a migraine-free period.
Topics: Adolescent; Adult; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Time Factors; Tryptamines | 1996 |
Inhibition of trigeminal neurons by intravenous administration of the serotonin (5HT)1B/D receptor agonist zolmitriptan (311C90): are brain stem sites therapeutic target in migraine?
Topics: Animals; Brain Stem; Cats; Cranial Sinuses; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Evoked Potentials; Injections, Intravenous; Migraine Disorders; Neural Inhibition; Neurons; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Trigeminal Caudal Nucleus; Tryptamines | 1996 |
311C90: patient profiles and typical case histories of migraine management.
Topics: Adult; Female; Humans; Male; Menstruation; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Time Factors; Tryptamines | 1997 |
Is a central action of acute antimigraine drugs essential?
Topics: Analgesics; Animals; Brain; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1997 |
Measuring central action of acute antimigraine drugs in humans.
Topics: Analgesics; Brain; Contingent Negative Variation; Electroencephalography; Evoked Potentials, Auditory; Evoked Potentials, Visual; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1997 |
Would any acute treatment for migraine demonstrate recurrence?
Topics: Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Recurrence; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Tryptamines | 1997 |
Attacking migraine headache from beginning to end.
Topics: Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1997 |
The clinical pharmacokinetics of zolmitriptan.
Topics: Absorption; Adult; Case-Control Studies; Female; Humans; Liver Diseases; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tissue Distribution; Tryptamines | 1997 |
Zolmitriptan receives migraine indication.
Topics: Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1998 |
Oral migraine treatment approved.
Topics: Administration, Oral; Contraindications; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Rabies Vaccines; Serotonin Receptor Agonists; Tryptamines; United States; United States Food and Drug Administration | 1998 |
A triptan too far?
Topics: Acute Disease; Clinical Trials as Topic; Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1998 |
Zolmitriptan for migraine.
Topics: Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Interactions; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Tryptamines | 1998 |
Cortical spreading depression-associated hyperemia in rats: involvement of serotonin.
Topics: Animals; Cerebrovascular Circulation; Cortical Spreading Depression; Hyperemia; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines | 1998 |
Comparison of more and less lipophilic serotonin (5HT1B/1D) agonists in a model of trigeminovascular nociception in cat.
Topics: Animals; Cats; Cerebrovascular Circulation; Cranial Sinuses; Electric Stimulation; Gene Expression Regulation; Genes, fos; Migraine Disorders; Neurons, Afferent; Nociceptors; Oxazoles; Oxazolidinones; Pain; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sumatriptan; Synaptic Transmission; Trigeminal Caudal Nucleus; Trigeminal Nerve; Trigeminal Nucleus, Spinal; Tryptamines; Vasoconstrictor Agents | 1998 |
It never hurts to check. Taking the time to read a label benefited this migraine sufferer.
Topics: Adult; Contraindications; Drug Labeling; Female; Humans; Medication Errors; Migraine Disorders; Oxazoles; Oxazolidinones; Patient Education as Topic; Reading; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1998 |
New "triptans" and other drugs for migraine.
Topics: Adrenergic beta-Antagonists; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Dihydroergotamine; Drug Interactions; Ergotamine; Humans; Indoles; Methysergide; Migraine Disorders; Naproxen; Oxazoles; Oxazolidinones; Piperidines; Propranolol; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Timolol; Triazoles; Tryptamines; Valproic Acid; Vasoconstrictor Agents | 1998 |
Cranial vascular effects of zolmitriptan, a centrally active 5-HT1B/1D receptor partial agonist for the acute treatment of migraine.
Topics: Animals; Arteriovenous Anastomosis; Blood Flow Velocity; Carotid Arteries; Cats; Cerebral Cortex; Disease Models, Animal; Dogs; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1998 |
The effects of 5-HT1A, 5-HT1B and 5-HT1D receptor agonists on trigeminal nociceptive neurotransmission in anaesthetized rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Analgesics; Animals; Electric Stimulation; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists; Trigeminal Caudal Nucleus; Tryptamines | 1998 |
[Zolmitriptan].
Topics: Chemistry, Pharmaceutical; Humans; Indoles; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1998 |
Headache after frequent use of serotonin agonists zolmitriptan and naratriptan.
Topics: Adult; Female; Headache; Humans; Indoles; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Serotonin Receptor Agonists; Tryptamines | 1999 |
Zolmitriptan.
Topics: Drug Interactions; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1999 |
Efficacy of 5HT in migraine.
Topics: Action Potentials; Animals; Cats; Cranial Sinuses; Electric Stimulation; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstrictor Agents | 1999 |
Measuring event-related potentials.
Topics: Adult; Arousal; Contingent Negative Variation; Dexfenfluramine; Event-Related Potentials, P300; Evoked Potentials, Auditory, Brain Stem; Humans; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Tryptamines | 1999 |
[Differentiated therapy of migraine attack].
Topics: Adult; Analgesics; Antiemetics; Aspirin; Combined Modality Therapy; Drug Therapy, Combination; Female; Humans; Male; Metoclopramide; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Severity of Illness Index; Treatment Outcome; Tryptamines | 1999 |
Determination of antimigraine compounds rizatriptan, zolmitriptan, naratriptan and sumatriptan in human serum by liquid chromatography/electrospray tandem mass spectrometry.
Topics: Bufotenin; Chromatography, High Pressure Liquid; Humans; Indoles; Mass Spectrometry; Migraine Disorders; Molecular Structure; Oxazoles; Oxazolidinones; Piperidines; Sensitivity and Specificity; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents | 2000 |
Spinal cord infarction during use of zolmitriptan: a case report.
Topics: Female; Humans; Infarction; Menstruation; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Spinal Cord; Tryptamines | 2000 |
Drug information incorrect.
Topics: Canada; Contraindications; Drug Interactions; France; Humans; Migraine Disorders; Oxazoles; Oxazolidinones; Propranolol; Serotonin Receptor Agonists; Tryptamines; Vasodilator Agents | 2000 |
Zolmitriptan reverses blink reflex changes induced during the migraine attack in humans.
Topics: Adolescent; Adult; Blinking; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Trigeminal Ganglion; Tryptamines; Vasoconstrictor Agents | 2000 |
Triptans to the rescue: effective therapy for migraine headaches in the workplace.
Topics: Absenteeism; Adult; Cost-Benefit Analysis; Efficiency; Female; Humans; Indoles; Injections, Subcutaneous; Male; Migraine Disorders; Oxazoles; Oxazolidinones; Piperidines; Randomized Controlled Trials as Topic; Self Administration; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome; Triazoles; Tryptamines; Workplace | 2000 |
Treatment options for acute migraine.
Topics: Acute Disease; Adult; Female; Humans; Migraine Disorders; Oxazolidinones; Patient Selection; Practice Guidelines as Topic; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents | 2000 |
Are triptans with enhanced lipophilicity used for the acute treatment of migraine associated with an increased consulting rate for depressive illness?
Topics: Cohort Studies; Depression; Female; Humans; Indoles; Male; Migraine Disorders; Oxazolidinones; Piperidines; Referral and Consultation; Regression Analysis; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2000 |
What is the optimal strategy for managing acute migraine headaches?
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Disabled Persons; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Metoclopramide; Migraine Disorders; Oxazolidinones; Patient Selection; Serotonin Receptor Agonists; Severity of Illness Index; Tryptamines | 2001 |
Zolmitriptan versus sumatriptan comparison trial.
Topics: Acute Disease; Clinical Trials as Topic; Communication; Humans; Migraine Disorders; Oxazolidinones; Publishing; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2001 |
An open preference study with sumatriptan 50 mg and zolmitriptan 2.5 mg in 100 migraine patients.
Topics: Adult; Chi-Square Distribution; Confidence Intervals; Cross-Over Studies; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 2001 |
Effect of rizatriptan and other triptans on the nausea symptom of migraine: a post hoc analysis.
Topics: Administration, Oral; Adult; Double-Blind Method; Humans; Indoles; Migraine Disorders; Nausea; Oxazolidinones; Piperidines; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents | 2001 |
The cost effectiveness of stratified care in the management of migraine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cost-Benefit Analysis; Decision Support Techniques; Female; Health Care Costs; Humans; Male; Migraine Disorders; Oxazolidinones; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Severity of Illness Index; Tryptamines | 2001 |
[Zolmitriptan in treatment of migraine attack--the ARES Study].
Topics: Adult; Female; Humans; Male; Middle Aged; Migraine Disorders; Oxazolidinones; Pain Measurement; Recurrence; Treatment Outcome; Tryptamines | 2000 |
Assessing patient preference in migraine treatment.
Topics: Clinical Trials as Topic; Humans; Migraine Disorders; Oxazolidinones; Patient Satisfaction; Research Design; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstrictor Agents | 2001 |
[Migraine: a disease, not a symptom].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Atenolol; Diagnosis, Differential; Dihydroergotamine; Flunarizine; GABA Agents; Humans; Indoramin; Methysergide; Migraine Disorders; Oxazolidinones; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines; Valproic Acid; Vasoconstrictor Agents; Vasodilator Agents | 2002 |
[Splenic infarction associated with Zolmitriptan use].
Topics: Female; Humans; Middle Aged; Migraine Disorders; Oxazolidinones; Serotonin Receptor Agonists; Splenic Infarction; Tryptamines | 2002 |
Comparison of triptan tablet consumption per attack: a prospective study of migraineurs in Spain.
Topics: Female; Humans; Indoles; Male; Migraine Disorders; Oxazolidinones; Piperidines; Prospective Studies; Serotonin Receptor Agonists; Sumatriptan; Tablets; Triazoles; Tryptamines | 2002 |