Page last updated: 2024-08-25

zoledronic acid and Progeria

zoledronic acid has been researched along with Progeria in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (9.09)	29.6817
2010's	9 (81.82)	24.3611
2020's	1 (9.09)	2.80

Authors

Authors	Studies
Cabral, WA; Collins, FS; Cubria, MB; DuBose, A; Erdos, MR; Kamalapathy, P; Karim, L; Masoudi, A; Nazarian, A; Oftadeh, R; Snyder, BD; Suarez, S	1
Baltrusaitis, K; Braddock, DT; Cleveland, RH; D'Agostino, RB; Gordon, CM; Gordon, LB; Kieran, MW; Kleinman, ME; Li, X; Liang, MG; Massaro, J; Snyder, B; Walters, M	1
Jiang, K	1
Acín-Perez, R; Andrés, V; Cabezas-Sánchez, P; Cámara, C; Enríquez, JA; Gonzalez-Gómez, C; López-Otín, C; Luque-García, JL; Megias, D; Osorio, FG; Rivera-Torres, J	1
Blondel, S; Cordette, V; de Sandre-Giovannoli, A; Djabali, K; Egesipe, AL; Jaskowiak, AL; Laabi, Y; Le Corf, A; Levy, N; Martinat, C; Navarro, C; Nissan, X; Peschanski, M	1
Brazier, J; Brown, WT; Campbell, SE; D'Agostino, RB; Gordon, LB; Kieran, MW; Kleinman, ME; Massaro, J	1
Hisama, FM; Martin, GM; Oshima, J	1
Badens, C; Bonello-Palot, N; Bourgeois, P; Dignat-George, F; Levy, N; Robert, S; Sabatier, F; Simoncini, S	1
Aizenbud, D; Dror, AD; Hazan-Molina, H	1
Cleveland, RH; D'Agostino, RB; Dowton, AA; Gerhard-Herman, M; Gordon, CM; Gordon, LB; Greer, MM; Huh, SY; Kieran, MW; Kleinman, ME; Liang, MG; Littlefield, K; Massaro, J; Miller, DT; Nazarian, A; Quinn, N; Shappell, H; Silvera, VM; Smoot, LB; Snyder, BD; Ullrich, NJ	1
Gruenbaum, Y; Meshorer, E	1

Trials

1 trial(s) available for zoledronic acid and Progeria

Article	Year
Clinical Trial of the Protein Farnesylation Inhibitors Lonafarnib, Pravastatin, and Zoledronic Acid in Children With Hutchinson-Gilford Progeria Syndrome. Circulation, 2016, Jul-12, Volume: 134, Issue:2 Topics: Bone and Bones; Carotid Arteries; Child, Preschool; Diphosphonates; Drug Therapy, Combination; Female; Humans; Imidazoles; Infant; Male; Piperidines; Pravastatin; Progeria; Prospective Studies; Protein Prenylation; Pyridines; Zoledronic Acid	2016

Article

Year

Clinical Trial of the Protein Farnesylation Inhibitors Lonafarnib, Pravastatin, and Zoledronic Acid in Children With Hutchinson-Gilford Progeria Syndrome.

Circulation, 2016, Jul-12, Volume: 134, Issue:2

Topics: Bone and Bones; Carotid Arteries; Child, Preschool; Diphosphonates; Drug Therapy, Combination; Female; Humans; Imidazoles; Infant; Male; Piperidines; Pravastatin; Progeria; Prospective Studies; Protein Prenylation; Pyridines; Zoledronic Acid

2016

Other Studies

10 other study(ies) available for zoledronic acid and Progeria

Article	Year
Evaluation of musculoskeletal phenotype of the G608G progeria mouse model with lonafarnib, pravastatin, and zoledronic acid as treatment groups. Proceedings of the National Academy of Sciences of the United States of America, 2020, 06-02, Volume: 117, Issue:22 Topics: Aging; Animals; Bone and Bones; Bone Density Conservation Agents; Cartilage; Disease Models, Animal; Femur; Glycosaminoglycans; Joints; Lamin Type A; Mice; Mice, Transgenic; Mutation; Osteoarthritis; Phenotype; Piperidines; Pravastatin; Progeria; Protein Processing, Post-Translational; Pyridines; X-Ray Microtomography; Zoledronic Acid	2020
Extraskeletal Calcifications in Hutchinson-Gilford Progeria Syndrome. Bone, 2019, Volume: 125 Topics: Calcinosis; Calcium; Child; Child, Preschool; Creatinine; Female; Fibroblast Growth Factor-23; Humans; In Vitro Techniques; Lamin Type A; Male; Parathyroid Hormone; Piperidines; Pravastatin; Progeria; Pyridines; Zoledronic Acid	2019
Drug development for progeria yields insights into normal aging. Nature medicine, 2013, Volume: 19, Issue:5 Topics: Aging; Child; Clinical Trials as Topic; Diphosphonates; Drug Discovery; Humans; Imidazoles; Lamin Type A; Mutation; Piperidines; Pravastatin; Progeria; Pyridines; Time Factors; Zoledronic Acid	2013
Identification of mitochondrial dysfunction in Hutchinson-Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture. Journal of proteomics, 2013, Oct-08, Volume: 91 Topics: Adenosine Triphosphate; Adolescent; Amino Acids; Animals; Child; Diphosphonates; Female; Fibroblasts; Galactose; Gene Expression Regulation; Glucose; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Lamin Type A; Male; Methionine; Mice; Mitochondria; Mutation; Nuclear Proteins; Oxygen Consumption; Pravastatin; Progeria; Protein Precursors; Proteomics; Skin; Zoledronic Acid	2013
Induced pluripotent stem cells reveal functional differences between drugs currently investigated in patients with hutchinson-gilford progeria syndrome. Stem cells translational medicine, 2014, Volume: 3, Issue:4 Topics: Animals; Anticholesteremic Agents; Bone Density Conservation Agents; Cell Differentiation; Cell Proliferation; Child; Child, Preschool; Diphosphonates; Female; Humans; Imidazoles; Induced Pluripotent Stem Cells; Infant; Lamin Type A; Male; Mice; Nuclear Proteins; Osteoblasts; Pravastatin; Prenylation; Progeria; Protein Precursors; Zoledronic Acid	2014
Impact of farnesylation inhibitors on survival in Hutchinson-Gilford progeria syndrome. Circulation, 2014, Jul-01, Volume: 130, Issue:1 Topics: Adolescent; Adult; Alkyl and Aryl Transferases; Atherosclerosis; Cause of Death; Child; Child, Preschool; Clinical Trials as Topic; Cohort Studies; Dimethylallyltranstransferase; Diphosphonates; Drug Therapy, Combination; Female; Genes, Dominant; Genotype; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Kaplan-Meier Estimate; Lamin Type A; Male; Multicenter Studies as Topic; Nuclear Proteins; Piperidines; Pravastatin; Progeria; Proportional Hazards Models; Protein Precursors; Protein Prenylation; Pyridines; Treatment Outcome; Young Adult; Zoledronic Acid	2014
An encouraging progress report on the treatment of progeria and its implications for atherogenesis. Circulation, 2014, Jul-01, Volume: 130, Issue:1 Topics: Diphosphonates; Female; Humans; Imidazoles; Lamin Type A; Male; Nuclear Proteins; Piperidines; Pravastatin; Progeria; Protein Precursors; Protein Prenylation; Pyridines; Zoledronic Acid	2014
Prelamin A accumulation in endothelial cells induces premature senescence and functional impairment. Atherosclerosis, 2014, Volume: 237, Issue:1 Topics: Atazanavir Sulfate; Cell Adhesion; Cell Proliferation; Cells, Cultured; Cellular Senescence; Diphosphonates; Endothelial Cells; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Inflammation; Intercellular Adhesion Molecule-1; Lamin Type A; Microscopy, Fluorescence; Monocytes; Neovascularization, Pathologic; Nuclear Proteins; Oligopeptides; Pravastatin; Progeria; Protein Precursors; Pyridines; Umbilical Cord; Umbilical Veins; Zoledronic Acid	2014
Treatment considerations in hutchinson-gilford progeria syndrome: a case report. The Journal of clinical pediatric dentistry, 2015,Winter, Volume: 39, Issue:2 Topics: Adolescent; Bone Density Conservation Agents; Cephalometry; Diphosphonates; Female; Humans; Imidazoles; Malocclusion; Odontogenesis; Patient Care Planning; Progeria; Retrognathia; Tooth Eruption; Tooth Extraction; Tooth Root; Tooth, Deciduous; Zoledronic Acid	2015
Rejuvenating premature aging. Nature medicine, 2008, Volume: 14, Issue:7 Topics: Animals; Bone Density Conservation Agents; Cell Nucleus; Diphosphonates; Disease Models, Animal; Drug Therapy, Combination; Farnesyltranstransferase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Lamin Type A; Longevity; Mice; Mice, Knockout; Nuclear Proteins; Pravastatin; Prenylation; Progeria; Protein Precursors; Tumor Suppressor Protein p53; Zoledronic Acid	2008