Page last updated: 2024-08-25

zoledronic acid and Pancreatic Neoplasms

zoledronic acid has been researched along with Pancreatic Neoplasms in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (12.50)29.6817
2010's10 (62.50)24.3611
2020's4 (25.00)2.80

Authors

AuthorsStudies
Cai, N; Han, S; Han, X; Li, X; Malwal, SR; Oldfield, E; Xia, Y; Yu, Z; Zhang, Y1
Katata, Y; Okawaki, M; Sawaki, A; Yamaguchi, Y; Yamamura, M2
Kawashiri, T; Kobayashi, D; Shimazoe, T; Tokunaga, A1
Fujiwara, K; Ishida, H; Kanamitsu, K; Shimada, A; Tsukahara, H; Washio, K1
Dalgleish, AG; Kasow, S; Samad, M; Smith, PL; Yogaratnam, Y1
Hakamada, K; Itoh, K; Kudo, D; Mimura, J; Nagase, H; Suto, A; Suto, S; Yoshida, E1
Baine, MJ; Batra, SK; Chen, S; Gupta, S; Jain, M; Johansson, SL; Kaur, S; Lazenby, A; Lester, K; Lin, C; Rachagani, S; Smith, L; Souchek, JJ; Zheng, D1
Bouvet, M; Chishima, T; Endo, I; Hassanein, MK; Hiroshima, Y; Hoffman, RM; Ichikawa, Y; Maawy, A; Matsuyama, R; Menen, R; Miwa, S; Momiyama, M; Mori, R; Murakami, T; Tanaka, K; Uehara, F; Yamamoto, M; Yano, S1
Bouvet, M; Endo, I; Fleming, JB; Hiroshima, Y; Hoffman, RM; Katz, MH; Maawy, AA1
Elsayed, M; Kobayashi, D; Kubota, T; Matsunaga, N; Matsuura, T; Murata, R; Ogino, T; Ohdo, S; Shimazoe, T; Tsurudome, Y; Watanabe, N; Yoshizawa, Y1
Kressley, A; Saif, MW; Smith, A1
Barth, P; Baumgart, S; Ellenrieder, V; Fernandez-Zapico, ME; Gress, TM; Hofbauer, LC; König, AO; Lomberk, G; Reutlinger, K; Singh, G; Singh, SK; Urrutia, R1
Cui, L; Fujita, H; Kozono, S; Maeyama, R; Mizumoto, K; Ohuchida, K; Tanaka, M; Toma, H; Tominaga, Y; Zhao, M1
Belt, BA; Gillanders, WE; Goedegebuure, P; Herndon, J; Hsieh, CS; Lee, HM; Linehan, DC; Mitchem, JB; Porembka, MR1
Abbruzzese, A; Boland, CR; Caraglia, M; D'Alessandro, A; Galea, E; Goel, A; Palmieri, C; Tagliaferri, P; Tassone, P; Venuta, S; Viscomi, C1

Other Studies

16 other study(ies) available for zoledronic acid and Pancreatic Neoplasms

ArticleYear
Farnesyl Pyrophosphate Synthase as a Target for Drug Development: Discovery of Natural-Product-Derived Inhibitors and Their Activity in Pancreatic Cancer Cells.
    Journal of medicinal chemistry, 2019, 12-12, Volume: 62, Issue:23

    Topics: Antineoplastic Agents; Binding Sites; Biological Products; Cell Line, Tumor; Cell Survival; Computational Biology; Geranyltranstransferase; Humans; Pancreatic Neoplasms; Protein Conformation

2019
Republication: A Prospective Observational Study of Adoptive Immunotherapy for Cancer Using Zoledronate-Activated Killer (ZAK) Cells - An Analysis for Patients With Incurable Pancreatic Cancer.
    Anticancer research, 2022, Volume: 42, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Resistance, Neoplasm; Female; Humans; Immunotherapy, Adoptive; Japan; Killer Cells, Natural; Lymphocyte Activation; Male; Middle Aged; Pancreatic Neoplasms; Prospective Studies; Salvage Therapy; Survival Analysis; Treatment Outcome; Zoledronic Acid

2022
Anti-tumor Activities of 3-Hydroxy-3-methylglutaryl Coenzyme A (HMG-CoA) Reductase Inhibitors and Bisphosphonates in Pancreatic Cell Lines Which Show Poor Responses to Gemcitabine.
    Biological & pharmaceutical bulletin, 2020, Volume: 43, Issue:1

    Topics: Alendronate; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Deoxycytidine; Gemcitabine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pancreatic Neoplasms; Zoledronic Acid

2020
A case of alveolar rhabdomyosarcoma showing concurrent responsive bone marrow lesions and refractory pancreatic lesions to pazopanib monotherapy.
    Pediatric blood & cancer, 2020, Volume: 67, Issue:9

    Topics: Adolescent; Bone Density Conservation Agents; Bone Marrow; Bone Marrow Neoplasms; Fluorodeoxyglucose F18; Forkhead Box Protein O1; Humans; Indazoles; Oncogene Proteins, Fusion; Paired Box Transcription Factors; Pancreatic Neoplasms; PAX3 Transcription Factor; Positron-Emission Tomography; Protein Kinase Inhibitors; Pyrimidines; Receptors, Vascular Endothelial Growth Factor; Rhabdomyosarcoma, Alveolar; Sulfonamides; Tumor Microenvironment; Zoledronic Acid

2020
Effect of Gemcitabine based chemotherapy on the immunogenicity of pancreatic tumour cells and T-cells.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2021, Volume: 23, Issue:1

    Topics: Annexin A5; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Dendritic Cells; Deoxycytidine; Drug Interactions; Gemcitabine; Histocompatibility Antigens Class I; Humans; Immunomodulation; Interferon-gamma; Lymphocyte Activation; Oxaliplatin; Pancreatic Neoplasms; Thalidomide; Zoledronic Acid

2021
Increase of Tumor Infiltrating γδ T-cells in Pancreatic Ductal Adenocarcinoma Through Remodeling of the Extracellular Matrix by a Hyaluronan Synthesis Suppressor, 4-Methylumbelliferone.
    Pancreas, 2019, Volume: 48, Issue:2

    Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Extracellular Matrix; Humans; Hyaluronic Acid; Hymecromone; Interleukin-2; Intraepithelial Lymphocytes; Leukocytes, Mononuclear; Lymphocytes, Tumor-Infiltrating; Mice, Inbred NOD; Mice, SCID; Pancreatic Neoplasms; Xenograft Model Antitumor Assays; Zoledronic Acid

2019
Unbiased analysis of pancreatic cancer radiation resistance reveals cholesterol biosynthesis as a novel target for radiosensitisation.
    British journal of cancer, 2014, Sep-09, Volume: 111, Issue:6

    Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Cholesterol; Diphosphonates; DNA, Complementary; Gene Expression Profiling; Gene Knockdown Techniques; Geranyltranstransferase; Humans; Imidazoles; Immunohistochemistry; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Pancreatic Neoplasms; Radiation Tolerance; Radiation-Sensitizing Agents; Zoledronic Acid

2014
The tumor-educated-macrophage increase of malignancy of human pancreatic cancer is prevented by zoledronic acid.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Animals; Cell Communication; Cell Line, Tumor; Cell Proliferation; Diphosphonates; Disease Models, Animal; Disease Progression; Heterografts; Humans; Imidazoles; Macrophages; Mice; Mitosis; Pancreatic Neoplasms; Zoledronic Acid

2014
Selective efficacy of zoledronic acid on metastasis in a patient-derived orthotopic xenograph (PDOX) nude-mouse model of human pancreatic cancer.
    Journal of surgical oncology, 2015, Volume: 111, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Deoxycytidine; Diphosphonates; Gemcitabine; Humans; Imidazoles; Immunoenzyme Techniques; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Neoplasm Metastasis; Pancreatic Neoplasms; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zoledronic Acid

2015
A Prospective Observational Study of Adoptive Immunotherapy for Cancer Using Zoledronate-Activated Killer (ZAK) Cells - An Analysis for Patients with Incurable Pancreatic Cancer.
    Anticancer research, 2016, Volume: 36, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cells, Cultured; Combined Modality Therapy; Deoxycytidine; Diphosphonates; Drug Combinations; Female; Gemcitabine; Humans; Imidazoles; Immunotherapy, Adoptive; Interleukin-2; Kaplan-Meier Estimate; Killer Cells, Lymphokine-Activated; Male; Middle Aged; Oxonic Acid; Pancreatic Neoplasms; Prospective Studies; Salvage Therapy; Tegafur; Treatment Outcome; Zoledronic Acid

2016
Synergistic Antiproliferative Effects of Zoledronic Acid and Fluvastatin on Human Pancreatic Cancer Cell Lines: An in Vitro Study.
    Biological & pharmaceutical bulletin, 2016, Aug-01, Volume: 39, Issue:8

    Topics: Anticholesteremic Agents; Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Cell Proliferation; Diphosphonates; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Imidazoles; Indoles; Mevalonic Acid; Pancreatic Neoplasms; Polyisoprenyl Phosphates; ras Proteins; rhoA GTP-Binding Protein; Zoledronic Acid

2016
Oral osteonecrosis associated with the use of zoledronic acid: first case of a patient with advanced pancreatic cancer and bone metastases.
    JOP : Journal of the pancreas, 2009, Mar-09, Volume: 10, Issue:2

    Topics: Adenocarcinoma; Bone Density Conservation Agents; Bone Neoplasms; Diphosphonates; Humans; Imidazoles; Jaw Diseases; Male; Middle Aged; Neoplasm Staging; Osteonecrosis; Pancreatic Neoplasms; Zoledronic Acid

2009
Disruption of a nuclear NFATc2 protein stabilization loop confers breast and pancreatic cancer growth suppression by zoledronic acid.
    The Journal of biological chemistry, 2011, Aug-19, Volume: 286, Issue:33

    Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Bone Density Conservation Agents; Breast Neoplasms; Cell Nucleus; Diphosphonates; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Imidazoles; Mice; Mice, Nude; Neoplasm Proteins; NFATC Transcription Factors; Pancreatic Neoplasms; Phosphorylation; Protein Stability; Protein Structure, Tertiary; Proto-Oncogene Proteins c-mdm2; Signal Transduction; Ubiquitination; Zoledronic Acid

2011
Significance of combination therapy of zoledronic acid and gemcitabine on pancreatic cancer.
    Cancer science, 2012, Volume: 103, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Blotting, Western; Bone Density Conservation Agents; Cell Movement; Cell Proliferation; Deoxycytidine; Diphosphonates; Drug Therapy, Combination; Female; Gemcitabine; Humans; Imidazoles; Immunoenzyme Techniques; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Tumor Cells, Cultured; Zoledronic Acid

2012
Pancreatic adenocarcinoma induces bone marrow mobilization of myeloid-derived suppressor cells which promote primary tumor growth.
    Cancer immunology, immunotherapy : CII, 2012, Volume: 61, Issue:9

    Topics: Adenocarcinoma; Animals; Bone Marrow Cells; Cell Differentiation; Diphosphonates; Disease Models, Animal; Humans; Imidazoles; Mice; Mice, Inbred C57BL; Myeloid Cells; Pancreatic Neoplasms; Tumor Microenvironment; Up-Regulation; Zoledronic Acid

2012
Zoledronic acid induces antiproliferative and apoptotic effects in human pancreatic cancer cells in vitro.
    British journal of cancer, 2003, Jun-16, Volume: 88, Issue:12

    Topics: Apoptosis; Cell Division; Diphosphonates; Humans; Imidazoles; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; Tumor Cells, Cultured; Zoledronic Acid

2003