Compounds > zoledronic acid
Page last updated: 2024-08-25

zoledronic acid and Osteoarthritis

zoledronic acid has been researched along with Osteoarthritis in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's8 (61.54)24.3611
2020's3 (23.08)2.80

Authors

AuthorsStudies
Ding, D; Feng, G; Jin, Q; Ma, L; Pei, X; Wang, L; Yan, J; Yang, Y; Zhou, Y1
Guo, XE; Hu, YJ; Lu, WW; Peng, Y; Tang, B; Wang, J; Wang, Z; Xu, L1
Cabral, WA; Collins, FS; Cubria, MB; DuBose, A; Erdos, MR; Kamalapathy, P; Karim, L; Masoudi, A; Nazarian, A; Oftadeh, R; Snyder, BD; Suarez, S1
Ashraf, S; Bennett, AJ; Burston, JJ; Chapman, V; Menhinick, MR; Poulter, CL; Sagar, DR; Walsh, DA; Xu, L1
Li, Y; Liu, F; Liu, M; Mao, Y; Wang, X; Yu, D; Zhao, X; Zhu, Z1
Budsberg, SC; Chambers, JN; Dearmin, MG; García, A; Trumble, TN1
Dontas, I; Khaldi, L; Lampropoulou-Adamidou, K; Lelovas, P; Papaioannou, NA; Stathopoulos, IP; Triantafillopoulos, IK; Vlamis, J1
Andresen, CJ; Bagi, CM; Berryman, E; Wilkie, D; Zakur, DE1
de Magalhães Souza Fialho, SC; Neves, FS; Pereira, IA; Ribeiro, G; Werner de Castro, GR; Zimmermann, AF1
Glasson, SS; Jian Li, X; Kennedy, JD; Leventhal, L; Mark, L; Piesla, MJ; Strassle, BW; Whiteside, GT1
Izmerov, NF; Karmanovskaia, SA; Marinkin, IO; Panacheva, LA; Poteriaeva, EL; Shpagina, LA1
Agnello, KA; Budsberg, SC; Chambers, JN; Seewald, W; Trumble, TN1
Green, J; Kuettner, KE; Muehleman, C; Sumner, DR; Thonar, EJ; Williams, JM1

Other Studies

13 other study(ies) available for zoledronic acid and Osteoarthritis

ArticleYear
Zoledronic acid generates a spatiotemporal effect to attenuate osteoarthritis by inhibiting potential Wnt5a-associated abnormal subchondral bone resorption.
    PloS one, 2022, Volume: 17, Issue:7

    Topics: Animals; Bone Resorption; Cartilage, Articular; Disease Models, Animal; Male; Osteoarthritis; Rats; Wnt-5a Protein; X-Ray Microtomography; Zoledronic Acid

2022
Early zoledronate treatment inhibits subchondral bone microstructural changes in skeletally-mature, ACL-transected canine knees.
    Bone, 2023, Volume: 167

    Topics: Animals; Anterior Cruciate Ligament Injuries; Bone and Bones; Cartilage, Articular; Disease Models, Animal; Dogs; Male; Meloxicam; Osteoarthritis; X-Ray Microtomography; Zoledronic Acid

2023
Evaluation of musculoskeletal phenotype of the G608G progeria mouse model with lonafarnib, pravastatin, and zoledronic acid as treatment groups.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 06-02, Volume: 117, Issue:22

    Topics: Aging; Animals; Bone and Bones; Bone Density Conservation Agents; Cartilage; Disease Models, Animal; Femur; Glycosaminoglycans; Joints; Lamin Type A; Mice; Mice, Transgenic; Mutation; Osteoarthritis; Phenotype; Piperidines; Pravastatin; Progeria; Protein Processing, Post-Translational; Pyridines; X-Ray Microtomography; Zoledronic Acid

2020
Osteoprotegerin reduces the development of pain behaviour and joint pathology in a model of osteoarthritis.
    Annals of the rheumatic diseases, 2014, Volume: 73, Issue:8

    Topics: Animals; Arthralgia; Behavior, Animal; Bone Density Conservation Agents; Bone Remodeling; Diphosphonates; Disease Models, Animal; Drug Design; Enzyme Inhibitors; Imidazoles; Iodoacetic Acid; Joints; Male; Nociceptors; Osteoarthritis; Osteoclasts; Osteophyte; Osteoprotegerin; Rats; Rats, Sprague-Dawley; Spinal Cord; Zoledronic Acid

2014
The inhibition of subchondral bone lesions significantly reversed the weight-bearing deficit and the overexpression of CGRP in DRG neurons, GFAP and Iba-1 in the spinal dorsal horn in the monosodium iodoacetate induced model of osteoarthritis pain.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Alkylating Agents; Animals; Arthritis, Experimental; Behavior, Animal; Bone Density Conservation Agents; Bone Marrow Diseases; Calcitonin Gene-Related Peptide; Calcium-Binding Proteins; Chronic Pain; Diphosphonates; DNA-Binding Proteins; Fluorescent Antibody Technique; Ganglia, Spinal; Glial Fibrillary Acidic Protein; Imidazoles; Iodoacetates; Knee Joint; Male; Microfilament Proteins; Neurons; Osteoarthritis; Rats; Rats, Sprague-Dawley; Spinal Cord; Weight-Bearing; X-Ray Microtomography; Zoledronic Acid

2013
Chondroprotective effects of zoledronic acid on articular cartilage in dogs with experimentally induced osteoarthritis.
    American journal of veterinary research, 2014, Volume: 75, Issue:4

    Topics: Alkaline Phosphatase; Animals; Bone Density Conservation Agents; Cartilage, Articular; Collagen; Diphosphonates; Dog Diseases; Dogs; Enzyme-Linked Immunosorbent Assay; Imidazoles; Male; Osteoarthritis; Radiography; Random Allocation; Stifle; Synovial Fluid; Zoledronic Acid

2014
Chondroprotective effect of high-dose zoledronic acid: An experimental study in a rabbit model of osteoarthritis.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2014, Volume: 32, Issue:12

    Topics: Animals; Bone Density Conservation Agents; Chondrocytes; Diphosphonates; Disease Models, Animal; Imidazoles; Male; Osteoarthritis; Rabbits; Zoledronic Acid

2014
Effect of antiresorptive and anabolic bone therapy on development of osteoarthritis in a posttraumatic rat model of OA.
    Arthritis research & therapy, 2015, Nov-06, Volume: 17

    Topics: Animals; Bone Density Conservation Agents; Cartilage, Articular; Chondrocytes; Diphosphonates; Disease Models, Animal; Humans; Imidazoles; Male; Osteoarthritis; Parathyroid Hormone; Rats; Rats, Inbred Lew; X-Ray Microtomography; Zoledronic Acid

2015
Flare-up of hand osteoarthritis caused by zoledronic acid infusion.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2010, Volume: 21, Issue:9

    Topics: Bone Density Conservation Agents; Diphosphonates; Female; Hand Joints; Humans; Imidazoles; Middle Aged; Osteoarthritis; Osteoporosis, Postmenopausal; Zoledronic Acid

2010
Inhibition of osteoclasts prevents cartilage loss and pain in a rat model of degenerative joint disease.
    Osteoarthritis and cartilage, 2010, Volume: 18, Issue:10

    Topics: Animals; Arthritis, Experimental; Bone Density; Bone Density Conservation Agents; Cartilage, Articular; Diphosphonates; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Imidazoles; Iodoacetates; Male; Osteoarthritis; Osteoclasts; Pain; Rats; Rats, Sprague-Dawley; Zoledronic Acid

2010
[Innovative approaches to diagnosis and treatment of occupational diseases (on joint diseases model)].
    Meditsina truda i promyshlennaia ekologiia, 2011, Issue:10

    Topics: Arthroscopy; Blood Coagulation; Cartilage, Articular; Combined Modality Therapy; Diphosphonates; Fibrinogen; Hemodynamics; Humans; Imidazoles; Knee Joint; Male; Middle Aged; Occupational Diseases; Osteoarthritis; Practice Guidelines as Topic; Ultrasonography; von Willebrand Factor; Zoledronic Acid

2011
Effects of zoledronate on markers of bone metabolism and subchondral bone mineral density in dogs with experimentally induced cruciate-deficient osteoarthritis.
    American journal of veterinary research, 2005, Volume: 66, Issue:9

    Topics: Alkaline Phosphatase; Amino Acids; Analysis of Variance; Animals; Anterior Cruciate Ligament; Bone and Bones; Bone Density; Bone Density Conservation Agents; Diphosphonates; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Imidazoles; Osteoarthritis; Osteocalcin; Time Factors; Tomography, X-Ray Computed; Zoledronic Acid

2005
The effect of bone remodeling inhibition by zoledronic acid in an animal model of cartilage matrix damage.
    Osteoarthritis and cartilage, 2002, Volume: 10, Issue:3

    Topics: Animals; Biomarkers; Bone Remodeling; Cartilage Diseases; Cartilage, Articular; Chymopapain; Collagen; Diphosphonates; Hindlimb; Imidazoles; Joints; Male; Models, Animal; Osteoarthritis; Proteoglycans; Rabbits; Zoledronic Acid

2002