Page last updated: 2024-08-25

zoledronic acid and Osteoarthritis, Knee

zoledronic acid has been researched along with Osteoarthritis, Knee in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (54.55)24.3611
2020's5 (45.45)2.80

Authors

AuthorsStudies
Cai, G; Jones, G; Laslett, LL; Zhang, X1
Aitken, D; Bowes, MA; Cai, G; Cicuttini, F; Conaghan, PG; Hill, C; Jones, G; Laslett, LL; March, L; Winzenberg, T; Wluka, AE1
Aitken, D; Antony, B; Blizzard, L; Cai, G; Cicuttini, F; Hill, C; Jones, G; Laslett, LL; March, L; Martel-Pelletier, J; Pelletier, JP; Wang, Y; Winzenberg, T; Wluka, AE1
Aspenberg, P; Brandt, J; Ledin, H; Ranstam, J; Roos, E; Schilcher, J1
Aitken, D; Cai, G; Cicuttini, F; Hill, C; Jones, G; Laslett, LL; March, L; Martel-Pelletier, J; Pelletier, JP; Wluka, AE1
Aitken, D; Blizzard, L; Cai, G; Cicuttini, F; Hill, C; Jones, G; Laslett, LL; March, L; Wang, Y; Wluka, AE1
Bolat, F; Cınar, BM; Karaeminogullari, O; Ozkoc, G; Sezgin, N; Tandogan, RN1
Harding, AK; Tägil, M; Toksvig-Larsen, S; W-Dahl, A1
Geijer, M; Harding, AK; Tägil, M; Toksvig-Larsen, S; W-Dahl, A1
Boon, P; Doré, DA; Jones, G; Laslett, LL; Quinn, SJ; Ryan, E; Winzenberg, TM1
Cao, L; Ding, HF; Liu, GW; Liu, S; Mao, YQ; Nie, SB; Wang, XQ; Yu, B; Yu, DG; Zhao, X; Zhu, ZA1

Reviews

1 review(s) available for zoledronic acid and Osteoarthritis, Knee

ArticleYear
Intravenous bisphosphonates do not improve knee pain or bone marrow lesions in people with knee osteoarthritis: a meta-analysis.
    Rheumatology (Oxford, England), 2022, 05-30, Volume: 61, Issue:6

    Topics: Bone Marrow; Cartilage Diseases; Diphosphonates; Humans; Knee Joint; Osteoarthritis, Knee; Pain; Zoledronic Acid

2022

Trials

7 trial(s) available for zoledronic acid and Osteoarthritis, Knee

ArticleYear
Effect of zoledronic acid with or without methylprednisolone on 3D bone area and bone shape in patients with symptomatic knee osteoarthritis: A post-hoc analysis of the ZAP2 trial.
    Seminars in arthritis and rheumatism, 2022, Volume: 56

    Topics: Disease Progression; Female; Femur; Humans; Knee Joint; Male; Methylprednisolone; Osteoarthritis, Knee; Zoledronic Acid

2022
Effect of Intravenous Zoledronic Acid on Tibiofemoral Cartilage Volume Among Patients With Knee Osteoarthritis With Bone Marrow Lesions: A Randomized Clinical Trial.
    JAMA, 2020, 04-21, Volume: 323, Issue:15

    Topics: Aged; Bone Density Conservation Agents; Bone Marrow; Bone Marrow Diseases; Cartilage, Articular; Double-Blind Method; Female; Humans; Infusions, Intravenous; Knee Joint; Male; Middle Aged; Osteoarthritis, Knee; Treatment Failure; Zoledronic Acid

2020
Single postoperative infusion of zoledronic acid to improve patient-reported outcome after hip or knee replacement: study protocol for a randomised, controlled, double-blinded clinical trial.
    BMJ open, 2020, 09-30, Volume: 10, Issue:9

    Topics: Arthroplasty, Replacement, Knee; Humans; Knee Prosthesis; Osteoarthritis, Knee; Patient Reported Outcome Measures; Randomized Controlled Trials as Topic; Sweden; Treatment Outcome; Zoledronic Acid

2020
A protocol for a multicentre, randomised, double-blind, placebo-controlled trial to compare the effect of annual infusions of zoledronic acid to placebo on knee structural change and knee pain over 24 months in knee osteoarthritis patients - ZAP2.
    BMC musculoskeletal disorders, 2018, Jul-18, Volume: 19, Issue:1

    Topics: Aged; Aged, 80 and over; Bone Density Conservation Agents; Double-Blind Method; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Knee Joint; Male; Middle Aged; Osteoarthritis, Knee; Pain; Time Factors; Treatment Outcome; Zoledronic Acid

2018
A single dose zoledronic acid enhances pin fixation in high tibial osteotomy using the hemicallotasis technique. A double-blind placebo controlled randomized study in 46 patients.
    Bone, 2010, Volume: 46, Issue:3

    Topics: Adult; Bone Nails; Coated Materials, Biocompatible; Diphosphonates; Double-Blind Method; Female; Humans; Imidazoles; Infusions, Intravenous; Male; Middle Aged; Osteoarthritis, Knee; Osteotomy; Surgical Fixation Devices; Tibia; Zoledronic Acid

2010
A single bisphosphonate infusion does not accelerate fracture healing in high tibial osteotomies.
    Acta orthopaedica, 2011, Volume: 82, Issue:4

    Topics: Absorptiometry, Photon; Adult; Bone Density; Bone Density Conservation Agents; Diphosphonates; Female; Fracture Healing; Humans; Imidazoles; Infusions, Intravenous; Male; Middle Aged; Osteoarthritis, Knee; Osteotomy; Tibia; Time Factors; Wound Healing; Zoledronic Acid

2011
Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial.
    Annals of the rheumatic diseases, 2012, Volume: 71, Issue:8

    Topics: Acute-Phase Reaction; Aged; Arthralgia; Bone Density Conservation Agents; Bone Marrow Diseases; Diphosphonates; Double-Blind Method; Female; Humans; Imidazoles; Infusions, Intravenous; Knee Joint; Male; Middle Aged; Osteoarthritis, Knee; Outcome Assessment, Health Care; Pain Measurement; Treatment Outcome; Zoledronic Acid

2012

Other Studies

3 other study(ies) available for zoledronic acid and Osteoarthritis, Knee

ArticleYear
The association between change in bone marrow lesion size and change in tibiofemoral cartilage volume and knee symptoms.
    Rheumatology (Oxford, England), 2021, 06-18, Volume: 60, Issue:6

    Topics: Arthralgia; Bone Density Conservation Agents; Bone Marrow; Bone Marrow Diseases; Cartilage, Articular; Double-Blind Method; Female; Femur; Glucocorticoids; Humans; Knee Joint; Magnetic Resonance Imaging; Male; Methylprednisolone; Middle Aged; Multicenter Studies as Topic; Osteoarthritis, Knee; Randomized Controlled Trials as Topic; Tibia; Time Factors; Zoledronic Acid

2021
Intra-articular zoledronic acid in a rat osteoarthritis model: significant reduced synovitis may indicate chondroprotective effect.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2015, Volume: 23, Issue:5

    Topics: Animals; Bone Density Conservation Agents; Cartilage, Articular; Chondrocytes; Diphosphonates; Disease Models, Animal; Disease Progression; Imidazoles; Injections, Intra-Articular; Male; Osteoarthritis, Knee; Rats; Rats, Wistar; Synovial Membrane; Synovitis; Zoledronic Acid

2015
Efficacy of zoledronic acid in treatment of teoarthritis is dependent on the disease progression stage in rat medial meniscal tear model.
    Acta pharmacologica Sinica, 2012, Volume: 33, Issue:7

    Topics: Animals; Bone Density Conservation Agents; Bone Remodeling; Calcitonin Gene-Related Peptide; Cartilage, Articular; Diphosphonates; Gene Expression; Imidazoles; Male; Osteoarthritis, Knee; Pain; Rats; Rats, Sprague-Dawley; Zoledronic Acid

2012