zoledronic acid has been researched along with Invasiveness, Neoplasm in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (31.03) | 29.6817 |
| 2010's | 20 (68.97) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Albanell, J; Bell, R; Cameron, D; Coleman, R; Dodwell, D; Gomis, RR; Gregory, W; Hall, A; Hanby, A; Jean-Mairet, J; Marshall, H; Rojo, F; Tercero, JC | 1 |
| Cao, Q; Chen, X; Dong, C; Huang, J; Huang, P; Liao, R; Ren, G; Tan, Y; Wang, L; Wu, X | 1 |
| Atkinson, C; Attia, J; Christie, D; Delahunt, B; Denham, JW; Diamond, T; Duchesne, G; Gogna, NK; Joseph, D; Kenny, L; Lamb, DS; Matthews, J; Oldmeadow, C; Spry, NA; Steigler, A; Tai, KH; Turner, S | 2 |
| Elahian, F; Lage, H; Mansouri, M; Mirzaei, SA; Mousavi, SS | 1 |
| Abal, M; Aguín, S; Alonso-Alconada, L; Carmona, M; Garcia, D; López-López, R; Martínez, N; Muinelo-Romay, L; Vieito, M | 1 |
| Ando, T; Cates, JM; Cole, HA; Haro, H; Ohba, T; Schoenecker, JG; Schwartz, HS; Slosky, DA | 1 |
| Barrett-Lee, P; Bell, R; Burkinshaw, R; Cameron, D; Coleman, R; Dodwell, D; Gil, M; Grieve, R; Hinsley, S; Keane, M; Liversedge, V; Marshall, H; Rathbone, E; Ritchie, D; Wilson, C | 1 |
| Lu, S; Song, Z; Yang, S; Yang, X; Yu, Y; Zhang, J | 1 |
| Bifulco, K; Bruzzese, F; Budillon, A; Carriero, MV; Ciardiello, C; Iannelli, F; Lombardi, R; Milone, MR; Pucci, B | 1 |
| Eaton, CL; Evans, CA; Fowles, A; Holen, I; Nutter, F; Ottewell, PD; Walker, M | 1 |
| Cheng, HL; Hsieh, MJ; Lin, CW; Lu, KH; Yang, JS; Yang, SF | 1 |
| Cserepes, M; Dobos, J; Hegedűs, B; Horváth, O; Izsák, V; Kenessey, I; Kói, K; Molnár, D; Tímár, J; Tóvári, J | 1 |
| Abbruzzese, A; Addeo, SR; Baldi, A; Budillon, A; Caraglia, M; Loeffler, M; Lupu, R; Marra, M; Meo, G; Rosolowski, M; Santini, D; Tonini, G; Vincenzi, B; Zappavigna, S | 1 |
| Athanasou, N; Balke, M; Campanacci, L; Gebert, C; Gibbons, M; Hogendoorn, P; Kroep, J; Picci, P; Taylor, R; Wass, J | 1 |
| Hildreth, BE; Lanigan, LG; Martin, CK; Pillai, SP; Rosol, TJ; Werbeck, JL; Wolfe, TD | 1 |
| Chen, JY; Hong, CQ; Huang, WL; Li, WB; Li, XY; Lin, YC; You, YJ | 1 |
| Chang, YC; Chen, JH; Cheng, JC; Chou, CH; Teng, CM; Tzen, KY | 1 |
| Koul, HK; Koul, S; Meacham, RB | 1 |
| Chen, JY; Hong, CQ; Huang, WL; Li, XY; Lin, W; Lin, YC; Wang, HB | 1 |
| Chang, JW; Chen, SM; Hsieh, LL; Li, YY; Yeh, KY | 1 |
| Denoyelle, C; Hong, L; Soria, C; Soria, J; Vannier, JP | 1 |
| Hiraga, T; Tamura, D; Ueda, A; Williams, PJ; Yoneda, T | 1 |
| Brown, MD; Clarke, NW; George, NJ; Hart, CA; Montague, R; Ramani, VA | 1 |
| Bielawski, KP; Bosse, U; Schlotter, CM; Vogt, U | 1 |
| Aogi, K; Asaga, T; Goessl, C; Iino, Y; Kohno, N; Minami, H; Nakamura, S; Ohashi, Y; Takashima, S; Watanabe, T | 1 |
| Coleman, RE; Holen, I; Neville-Webbe, HL; Woodward, JK | 1 |
| Altieri, V; Autorino, R; Benincasa, G; D'Armiento, M; De Placido, S; Di Lorenzo, G; Giordano, A; Giuliano, M; Morelli, E; Napodano, G; Russo, A | 1 |
| Boissier, S; Clézardin, P; Colombel, M; Delaissé, JM; Delmas, P; Ebetino, FH; Ferreras, M; Magnetto, S; Peyruchaud, O | 1 |
1 review(s) available for zoledronic acid and Invasiveness, Neoplasm
| Article | Year |
|---|---|
New role for an established drug? Bisphosphonates as potential anticancer agents.
Topics: Animals; Antineoplastic Agents; Bone and Bones; Bone Density; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Clinical Trials as Topic; Diphosphonates; Drug Synergism; Female; Humans; Imidazoles; Male; Neoplasm Invasiveness; Neovascularization, Pathologic; Osteoclasts; Prostatic Neoplasms; Retrospective Studies; Zoledronic Acid | 2012 |
6 trial(s) available for zoledronic acid and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Effect of MAF amplification on treatment outcomes with adjuvant zoledronic acid in early breast cancer: a secondary analysis of the international, open-label, randomised, controlled, phase 3 AZURE (BIG 01/04) trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Diphosphonates; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Imidazoles; Kaplan-Meier Estimate; Mastectomy; Maximum Tolerated Dose; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Proportional Hazards Models; Prospective Studies; Proto-Oncogene Proteins c-maf; Survival Analysis; Treatment Outcome; Zoledronic Acid | 2017 |
Short-term androgen suppression and radiotherapy versus intermediate-term androgen suppression and radiotherapy, with or without zoledronic acid, in men with locally advanced prostate cancer (TROG 03.04 RADAR): 10-year results from a randomised, phase 3,
Topics: Aged; Androgen Antagonists; Australia; Brachytherapy; Cause of Death; Combined Modality Therapy; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Grading; Neoplasm Invasiveness; Neoplasm Staging; New Zealand; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Assessment; Survival Analysis; Time Factors; Treatment Outcome; Zoledronic Acid | 2019 |
Adjuvant zoledronic acid in patients with early breast cancer: final efficacy analysis of the AZURE (BIG 01/04) randomised open-label phase 3 trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Confidence Intervals; Diphosphonates; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Early Detection of Cancer; Female; Follow-Up Studies; Humans; Imidazoles; Infusions, Intravenous; International Cooperation; Kaplan-Meier Estimate; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Prospective Studies; Survival Rate; Treatment Outcome; Zoledronic Acid | 2014 |
Short-term androgen suppression and radiotherapy versus intermediate-term androgen suppression and radiotherapy, with or without zoledronic acid, in men with locally advanced prostate cancer (TROG 03.04 RADAR): an open-label, randomised, phase 3 factorial
Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Brachytherapy; Combined Modality Therapy; Diphosphonates; Disease-Free Survival; Drug Administration Schedule; Follow-Up Studies; Humans; Imidazoles; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Prostate-Specific Antigen; Prostatic Neoplasms; Survival Analysis; Treatment Outcome; Zoledronic Acid | 2014 |
Zoledronic acid significantly reduces skeletal complications compared with placebo in Japanese women with bone metastases from breast cancer: a randomized, placebo-controlled trial.
Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Diphosphonates; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Imidazoles; Infusions, Intravenous; Japan; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Prognosis; Proportional Hazards Models; Reference Values; Risk Assessment; Survival Analysis; Treatment Outcome; Zoledronic Acid | 2005 |
Phase II trial of gemcitabine, prednisone, and zoledronic acid in pretreated patients with hormone refractory prostate cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Diphosphonates; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Neoplasm; Follow-Up Studies; Gemcitabine; Humans; Imidazoles; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Neoplasms, Hormone-Dependent; Pain Measurement; Palliative Care; Prednisone; Probability; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Assessment; Survival Rate; Treatment Outcome; Zoledronic Acid | 2007 |
22 other study(ies) available for zoledronic acid and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Inhibition of UGT8 suppresses basal-like breast cancer progression by attenuating sulfatide-αVβ5 axis.
Topics: Animals; Biosynthetic Pathways; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Disease Progression; Female; Ganglioside Galactosyltransferase; Gene Expression Regulation, Neoplastic; Humans; Mice, SCID; Neoplasm Invasiveness; Neoplasm Metastasis; Receptors, Vitronectin; Signal Transduction; SOXE Transcription Factors; Sulfoglycosphingolipids; Survival Analysis; Up-Regulation; Zoledronic Acid | 2018 |
The cell cycle arrest and the anti-invasive effects of nitrogen-containing bisphosphonates are not mediated by DBF4 in breast cancer cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diphosphonates; Drug Screening Assays, Antitumor; Etidronic Acid; Female; Humans; Imidazoles; Inhibitory Concentration 50; Neoplasm Invasiveness; Pamidronate; Risedronic Acid; Zoledronic Acid | 2014 |
Zoledronic acid as an antimetastatic agent for different human tumor cell lines.
Topics: Cell Line, Tumor; Diphosphonates; Humans; Imidazoles; Neoplasm Invasiveness; Neoplasm Metastasis; Zoledronic Acid | 2013 |
Bisphosphonates inhibit osteosarcoma-mediated osteolysis via attenuation of tumor expression of MCP-1 and RANKL.
Topics: Animals; Bone Resorption; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Chemokine CCL2; Diphosphonates; Humans; Imidazoles; Mice; Monocytes; Neoplasm Invasiveness; Osteoclasts; Osteogenesis; Osteolysis; Osteoprotegerin; Osteosarcoma; RANK Ligand; Zoledronic Acid | 2014 |
Everolimus and zoledronic acid--a potential synergistic treatment for lung adenocarcinoma bone metastasis.
Topics: Animals; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Diphosphonates; Drug Synergism; Drug Therapy, Combination; Everolimus; Humans; Imidazoles; Lung Neoplasms; Mice; Neoplasm Invasiveness; Phosphorylation; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Zoledronic Acid | 2014 |
Proteomic analysis of zoledronic-acid resistant prostate cancer cells unveils novel pathways characterizing an invasive phenotype.
Topics: Blotting, Western; Bone Density Conservation Agents; Cell Movement; Cell Proliferation; Diphosphonates; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Gene Ontology; Gene Regulatory Networks; Humans; Imidazoles; Male; Neoplasm Invasiveness; Prostatic Neoplasms; Proteomics; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tumor Cells, Cultured; Zoledronic Acid | 2015 |
Oestrogen receptor positive breast cancer metastasis to bone: inhibition by targeting the bone microenvironment in vivo.
Topics: Animals; Bone Density Conservation Agents; Bone Neoplasms; Bone Remodeling; Breast Neoplasms; Cell Line, Tumor; Diphosphonates; Enzyme-Linked Immunosorbent Assay; Estradiol; Female; Flow Cytometry; Humans; Imidazoles; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Receptors, Estrogen; Tumor Microenvironment; X-Ray Microtomography; Xenograft Model Antitumor Assays; Zoledronic Acid | 2016 |
Zoledronate blocks geranylgeranylation not farnesylation to suppress human osteosarcoma U2OS cells metastasis by EMT via Rho A activation and FAK-inhibited JNK and p38 pathways.
Topics: Biological Transport; Bone Density Conservation Agents; Bone Neoplasms; Cadherins; cdc42 GTP-Binding Protein; Cell Line, Tumor; Cell Movement; Cell Survival; Diphosphonates; Diterpenes; Epithelial-Mesenchymal Transition; Farnesol; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Neoplasm Invasiveness; Nuclear Proteins; Osteoporosis; Osteosarcoma; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Prenylation; Proto-Oncogene Proteins pp60(c-src); rho-Associated Kinases; Snail Family Transcription Factors; Twist-Related Protein 1; Zoledronic Acid | 2016 |
KRAS-mutation status dependent effect of zoledronic acid in human non-small cell cancer preclinical models.
Topics: A549 Cells; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Movement; Cell Proliferation; Cisplatin; Diphosphonates; Dose-Response Relationship, Drug; Genetic Predisposition to Disease; Humans; Imidazoles; Lung Neoplasms; Male; Mice, Inbred BALB C; Mice, SCID; Mutation; Neoplasm Invasiveness; Neovascularization, Pathologic; Phenotype; Proto-Oncogene Proteins p21(ras); Signal Transduction; Tumor Burden; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays; Zoledronic Acid | 2016 |
Cyr61 downmodulation potentiates the anticancer effects of zoledronic acid in androgen-independent prostate cancer cells.
Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cysteine-Rich Protein 61; Diphosphonates; Humans; Imidazoles; Male; Neoplasm Invasiveness; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Prenylation; Signal Transduction; Zoledronic Acid | 2009 |
Bisphosphonate treatment of aggressive primary, recurrent and metastatic Giant Cell Tumour of Bone.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Bone Resorption; Diphosphonates; Female; Giant Cell Tumor of Bone; Humans; Imidazoles; Lung Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Osteoclasts; Treatment Outcome; Tumor Cells, Cultured; Young Adult; Zoledronic Acid | 2010 |
Effect of zoledronic acid and amputation on bone invasion and lung metastasis of canine osteosarcoma in nude mice.
Topics: Amputation, Surgical; Animals; Antineoplastic Agents; Bone Neoplasms; Diphosphonates; Dog Diseases; Dogs; Female; Imidazoles; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Invasiveness; Osteosarcoma; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zoledronic Acid | 2011 |
Zoledronic acid inhibits proliferation and impairs migration and invasion through downregulating VEGF and MMPs expression in human nasopharyngeal carcinoma cells.
Topics: Blotting, Western; Bone Density Conservation Agents; Carcinoma; Cell Adhesion; Cell Movement; Cell Proliferation; Diphosphonates; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Humans; Imidazoles; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Zoledronic Acid | 2012 |
MMP-9 from sublethally irradiated tumor promotes Lewis lung carcinoma cell invasiveness and pulmonary metastasis.
Topics: Animals; Carcinoma, Lewis Lung; Chick Embryo; Diphosphonates; Imidazoles; Lung Neoplasms; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Zoledronic Acid | 2012 |
[Inhibitory effects of zoledronic acid on cell proliferation and invasion in human nasopharyngeal carcinoma cell line HNE1].
Topics: Carcinoma; Cell Line, Tumor; Cell Proliferation; Diphosphonates; Humans; Imidazoles; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Vascular Endothelial Growth Factor A; Zoledronic Acid | 2011 |
Low-dose zoledronic acid reduces spinal cord metastasis in pulmonary adenocarcinoma with neuroendocrine differentiation.
Topics: Animals; Antineoplastic Agents; Carcinoma, Neuroendocrine; Cell Differentiation; Cell Line, Tumor; Cloning, Molecular; Diphosphonates; Dose-Response Relationship, Drug; Flow Cytometry; Gene Knockdown Techniques; Green Fluorescent Proteins; Imidazoles; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Transplantation; Neural Cell Adhesion Molecules; RNA, Small Interfering; Spinal Cord Neoplasms; Transfection; Zoledronic Acid | 2012 |
New insights into the actions of bisphosphonate zoledronic acid in breast cancer cells by dual RhoA-dependent and -independent effects.
Topics: Bone Resorption; Breast Neoplasms; Cell Movement; Chemokine CXCL12; Chemokines, CXC; Cyclooxygenase 2; Dinoprostone; Diphosphonates; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Humans; Imidazoles; Isoenzymes; Membrane Proteins; Neoplasm Invasiveness; Neoplasm Metastasis; Osteolysis; Prostaglandin-Endoperoxide Synthases; rhoA GTP-Binding Protein; Tumor Cells, Cultured; Zoledronic Acid | 2003 |
Zoledronic acid inhibits visceral metastases in the 4T1/luc mouse breast cancer model.
Topics: Animals; Apoptosis; Blotting, Western; Bone Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Separation; Cell Survival; Diphosphonates; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Imidazoles; Luciferases; Lung Neoplasms; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Neoplasm Invasiveness; Neoplasm Metastasis; Osteoclasts; Time Factors; Zoledronic Acid | 2004 |
Differential inhibition of invasion and proliferation by bisphosphonates: anti-metastatic potential of Zoledronic acid in prostate cancer.
Topics: Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Diphosphonates; Epithelial Cells; Humans; Imidazoles; Male; Matrix Metalloproteinases; Neoplasm Invasiveness; Neoplasm Metastasis; Prostatic Neoplasms; Zoledronic Acid | 2004 |
Breast tumour growth inhibition in vitro through the combination of cyclophosphamide/metotrexate/5-fluorouracil, epirubicin/cyclophosphamide, epirubicin/paclitaxel, and epirubicin/docetaxel with the bisphosphonates ibandronate and zoledronic acid.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Cyclophosphamide; Diphosphonates; Docetaxel; Drug Synergism; Epirubicin; Female; Fluorouracil; Humans; Ibandronic Acid; Imidazoles; In Vitro Techniques; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasms, Ductal, Lobular, and Medullary; Paclitaxel; Taxoids; Zoledronic Acid | 2004 |
Combined effects of zoledronic acid and doxorubicin on breast cancer cell invasion in vitro.
Topics: Antibiotics, Antineoplastic; Apoptosis; Breast Neoplasms; Cell Movement; Cell Proliferation; Collagen; Diphosphonates; Doxorubicin; Drug Combinations; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imidazoles; In Vitro Techniques; Laminin; Neoplasm Invasiveness; Proteoglycans; Tumor Cells, Cultured; Zoledronic Acid | 2005 |
Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Bone Neoplasms; Breast Neoplasms; Cell Adhesion; Cell Cycle; Cell Movement; Clodronic Acid; Collagen; Diphosphonates; Dose-Response Relationship, Drug; Drug Combinations; Flow Cytometry; Fluorometry; Humans; Ibandronic Acid; Imidazoles; Laminin; Male; Matrix Metalloproteinases; Neoplasm Invasiveness; Neoplasm Metastasis; Paclitaxel; Prostatic Neoplasms; Proteoglycans; Pyridines; Pyridinium Compounds; Tumor Cells, Cultured; Zinc; Zoledronic Acid | 2000 |