zoledronic acid has been researched along with Angiogenesis, Pathologic in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (27.03) | 29.6817 |
| 2010's | 26 (70.27) | 24.3611 |
| 2020's | 1 (2.70) | 2.80 |
| Authors | Studies |
|---|---|
| Birkmann, J; Hoeres, T; Holzmann, E; Schulze-Tanzil, G; Smetak, M; Wilhelm, M | 1 |
| Calero-Paniagua, I; Fuentes-Calvo, I; García-Ortiz, L; González-Sarmiento, R; Martínez-Salgado, C; Moledo-Pouso, C; Pino-Montes, JD; Usategui-Martín, R | 1 |
| Guo, T; Liu, D; Liu, J; Pan, J; Wang, Q | 1 |
| Chen, D; Deng, Y; Hu, H; Qiao, M; Zang, X; Zhang, X; Zhao, X | 1 |
| Bafaloukos, D; Karagianni, A; Linardou, H; Michalakakou, K; Nicolatou-Galitis, O; Papadopoulou, E; Papassotiriou, I; Tarampikou, A; Tsixlakis, K; Vardas, E | 1 |
| Bocca, P; Cilli, M; Cipollone, G; Di Carlo, E; Emionite, L; Morandi, F; Pistoia, V; Prigione, I; Raffaghello, L | 1 |
| Chai, ZT; Gao, DM; Kong, LQ; Lu, L; Sun, HC; Tang, ZY; Wang, L; Wang, WQ; Wu, WZ; Xu, HX; Zhang, JB; Zhang, W; Zhu, XD; Zhuang, PY | 1 |
| Badens, C; Bonello-Palot, N; Bourgeois, P; Dignat-George, F; Levy, N; Robert, S; Sabatier, F; Simoncini, S | 1 |
| Hattori, Y; Kawano, K; Sakaida, C; Yamashita, J; Yonemochi, E | 1 |
| Consolini, R; Failli, A; Legitimo, A; Orsini, G; Romanini, A | 1 |
| Aslan, B; Calin, G; Dalton, HJ; Del C Monroig, P; Fernandez-de Thomas, RJ; Fuentes-Mattei, E; Gonzalez-Villasana, V; Ivan, C; Kahraman, N; Kanlikilicer, P; Lopez-Berestein, G; Ozpolat, B; Pradeep, S; Previs, RA; Rodriguez-Aguayo, C; Sood, AK; Velazquez-Torres, G; Wang, H | 1 |
| Cheng, J; Hong, Q; Jia, X; Lei, L; Li, D; Li, J; Liu, G; Mo, M; Shao, Z; Shen, Z; Wang, Y | 1 |
| Chiarugi, P; Comito, G; Giannoni, E; Lanciotti, M; Morandi, A; Pons Segura, C; Serni, S; Taddei, ML | 1 |
| Cserepes, M; Dobos, J; Hegedűs, B; Horváth, O; Izsák, V; Kenessey, I; Kói, K; Molnár, D; Tímár, J; Tóvári, J | 1 |
| Allocca, G; Brown, NJ; DeCristo, MJ; Haider, MT; Holen, I; McAllister, SS; Silver, DP; Ubellacker, JM | 1 |
| Boccadoro, M; Bosia, A; Cavallo, F; Coscia, M; Curcio, C; Forni, G; Holen, I; Iezzi, M; Massaia, M; Mönkkönen, H; Musiani, P; Pantaleoni, F; Quaglino, E; Riganti, C | 1 |
| D'Auria, F; Dammacco, F; Di Pietro, G; Ditonno, P; Gnoni, A; Guarini, A; Mangialardi, G; Moschetta, M; Musto, P; Ria, R; Ribatti, D; Ricciardi, MR; Vacca, A | 1 |
| Berardi, R; Bertoldo, F; Calipari, N; Fratto, ME; Ibrahim, T; Ottaviani, D; Sabbatini, R; Santini, D; Virzi, V | 1 |
| Bellahcène, A; Benzaïd, I; Castronovo, V; Clézardin, P; Colombel, M; Ebetino, FH; Fournier, PG; Mönkkönen, H; Stresing, V | 1 |
| Green, JR; Guenther, A | 1 |
| Abbruzzese, A; Ascani, R; Calimeri, T; Caraglia, M; Cigliana, G; De Rosa, G; Franco, R; La Rotonda, MI; Leonetti, C; Liguori, G; Marra, M; Salzano, G; Scarsella, M; Tagliaferri, P; Tassone, P; Zappavigna, S | 1 |
| Feng, X; Fu, D; He, X; Lin, T; Xu, W; Yang, S | 1 |
| Koul, HK; Koul, S; Meacham, RB | 1 |
| Brown, HK; Brown, NJ; Coleman, RE; Cross, SS; Holen, I; Jones, M; Ottewell, PD; Rogers, TL | 1 |
| Metcalf, S; Morgan, R; Pandha, HS | 1 |
| Caraglia, M; Castellano, M; De Cicco, F; Leonetti, C; Misso, G; Porru, M; Santini, D; Stoppacciaro, A | 1 |
| Brufsky, AM; Oesterreich, S; Steinman, RA | 1 |
| Croucher, PI; De Hendrik, R; Green, J; Hijzen, A; Lippitt, J; Perry, MJ; Shipman, CM; Van Camp, B; Van Marck, E; Vanderkerken, K | 1 |
| Tanvetyanon, T | 1 |
| Giraudo, E; Hanahan, D; Inoue, M | 1 |
| Battistoni, F; Dicuonzo, G; Gasparro, S; Gavasci, M; Grilli, C; La Cesa, A; Rocci, L; Santini, D; Tonini, G; Vincenzi, B; Virzì, V | 1 |
| Choong, PF; Dass, CR; Tran, TM | 1 |
| Carlini, P; Cognetti, F; Fabi, A; Felici, A; Ferretti, G; Papaldo, P; Tomao, S | 1 |
| Barazzetta, FM; Colombo, MP; Melani, C; Sangaletti, S; Werb, Z | 1 |
| Bertieri, R; Boccarelli, A; Cirulli, T; Coluccia, AM; Coluccia, M; Dammacco, F; Di Pietro, G; Giannini, T; Mangialardi, G; Ribatti, D; Scavelli, C; Vacca, A | 1 |
| Ahn, GO; Brown, JM | 1 |
| Kalomenidis, I; Karabela, S; Kollintza, A; Loutrari, H; Magkouta, S; Moschos, C; Papiris, SA; Psallidas, I; Roussos, C; Stathopoulos, GT; Zhou, Z | 1 |
6 review(s) available for zoledronic acid and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Can we consider zoledronic acid a new antitumor agent? Recent evidence in clinical setting.
Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Diphosphonates; Female; Humans; Imidazoles; Male; Mice; Middle Aged; Neoadjuvant Therapy; Neovascularization, Pathologic; Zoledronic Acid | 2010 |
The backbone of progress--preclinical studies and innovations with zoledronic acid.
Topics: Animals; Apoptosis; Bone and Bones; Bone Density Conservation Agents; Bone Neoplasms; Bone Resorption; Cell Line, Tumor; Cell Proliferation; Diphosphonates; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Imidazoles; Mice; Multiple Myeloma; Neovascularization, Pathologic; Osteoclasts; Zoledronic Acid | 2011 |
New role for an established drug? Bisphosphonates as potential anticancer agents.
Topics: Animals; Antineoplastic Agents; Bone and Bones; Bone Density; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Clinical Trials as Topic; Diphosphonates; Drug Synergism; Female; Humans; Imidazoles; Male; Neoplasm Invasiveness; Neovascularization, Pathologic; Osteoclasts; Prostatic Neoplasms; Retrospective Studies; Zoledronic Acid | 2012 |
Antiangiogenic effects of zoledronate on cancer neovasculature.
Topics: Angiogenesis Inhibitors; Animals; Bone Neoplasms; Diphosphonates; Endothelial Cells; Humans; Imidazoles; Neoplasms; Neovascularization, Pathologic; Zoledronic Acid | 2011 |
Zoledronic acid effectiveness against breast cancer metastases - a role for estrogen in the microenvironment?
Topics: Animals; Antineoplastic Agents; Bone and Bones; Bone Density Conservation Agents; Breast Neoplasms; Cell Movement; Diphosphonates; Drug Resistance, Neoplasm; Estrogens; Female; Humans; Imidazoles; Immunity; Intercellular Signaling Peptides and Proteins; Neovascularization, Pathologic; Signal Transduction; Tumor Microenvironment; Zoledronic Acid | 2012 |
Angiogenesis inhibitors and the need for anti-angiogenic therapeutics.
Topics: Angiogenesis Inhibitors; Angiostatins; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizumab; Diphosphonates; Endostatins; Eye Proteins; Humans; Imidazoles; Neoplasms; Neovascularization, Pathologic; Nerve Growth Factors; Serpins; Zoledronic Acid | 2007 |
31 other study(ies) available for zoledronic acid and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Immune cells regulate VEGF signalling via release of VEGF and antagonistic soluble VEGF receptor-1.
Topics: Adult; Cell Line, Tumor; Female; Humans; Interleukin-2; Killer Cells, Natural; Male; Middle Aged; Neovascularization, Pathologic; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; T-Lymphocytes; Vascular Endothelial Growth Factor A; Young Adult; Zoledronic Acid | 2018 |
Influence Of Angiogenic Mediators And Bone Remodelling In Paget´s Disease Of Bone.
Topics: Aged; Aged, 80 and over; Bone Density Conservation Agents; Bone Remodeling; Cohort Studies; Cytokines; Female; Humans; Male; Neovascularization, Pathologic; Osteitis Deformans; Osteoprotegerin; RANK Ligand; Spain; Zoledronic Acid | 2018 |
Epidermal Growth Factor Reverses the Inhibitory Effects of the Bisphosphonate, Zoledronic Acid, on Human Oral Keratinocytes and Human Vascular Endothelial Cells In Vitro via the Epidermal Growth Factor Receptor (EGFR)/Akt/Phosphoinositide 3-Kinase (PI3K)
Topics: Apoptosis; Bisphosphonate-Associated Osteonecrosis of the Jaw; Cell Movement; Cell Proliferation; Cell Survival; Endothelial Cells; Epidermal Growth Factor; ErbB Receptors; Human Umbilical Vein Endothelial Cells; Humans; Keratinocytes; Neovascularization, Pathologic; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Zoledronic Acid | 2019 |
Targeted Delivery of Zoledronate to Tumor-Associated Macrophages for Cancer Immunotherapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Hydrogen-Ion Concentration; Immunotherapy; Inhibitory Concentration 50; Injections, Intraventricular; Lipids; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nanoparticles; Neovascularization, Pathologic; RAW 264.7 Cells; Sarcoma 180; Tissue Distribution; Tumor Burden; Tumor Microenvironment; Xenograft Model Antitumor Assays; Zoledronic Acid | 2019 |
The use of crevicular fluid to assess markers of inflammation and angiogenesis, IL-17 and VEGF, in patients with solid tumors receiving zoledronic acid and/or bevacizumab.
Topics: Aged; Aged, 80 and over; Bevacizumab; Biomarkers; Drug Therapy, Combination; Female; Gingival Crevicular Fluid; Humans; Inflammation; Interleukin-17; Male; Middle Aged; Neoplasms; Neovascularization, Pathologic; Osteonecrosis; Periodontal Diseases; Periodontal Pocket; Predictive Value of Tests; Vascular Endothelial Growth Factor A; Zoledronic Acid | 2020 |
Mechanisms of the antitumor activity of human Vγ9Vδ2 T cells in combination with zoledronic acid in a preclinical model of neuroblastoma.
Topics: Adoptive Transfer; Animals; Apoptosis; Cell Line, Tumor; Chemokine CXCL10; Combined Modality Therapy; Cytotoxicity, Immunologic; Diphosphonates; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Humans; Imidazoles; Immunophenotyping; Interferon-gamma; Lymphocytes, Tumor-Infiltrating; Mice; Neovascularization, Pathologic; Neuroblastoma; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocyte Subsets; Treatment Outcome; Tumor Microenvironment; Xenograft Model Antitumor Assays; Zoledronic Acid | 2013 |
Antiangiogenic therapy promoted metastasis of hepatocellular carcinoma by suppressing host-derived interleukin-12b in mouse models.
Topics: Angiogenesis Inhibitors; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Dendritic Cells; Diphosphonates; Heterografts; Humans; Imidazoles; Immunosuppression Therapy; Indoles; Interleukin-12 Subunit p40; Killer Cells, Natural; Liver Neoplasms; Lung Neoplasms; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Neoplasm Transplantation; Neoplastic Cells, Circulating; Neovascularization, Pathologic; Niacinamide; Phenylurea Compounds; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Sorafenib; Sunitinib; Zoledronic Acid | 2013 |
Prelamin A accumulation in endothelial cells induces premature senescence and functional impairment.
Topics: Atazanavir Sulfate; Cell Adhesion; Cell Proliferation; Cells, Cultured; Cellular Senescence; Diphosphonates; Endothelial Cells; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Inflammation; Intercellular Adhesion Molecule-1; Lamin Type A; Microscopy, Fluorescence; Monocytes; Neovascularization, Pathologic; Nuclear Proteins; Oligopeptides; Pravastatin; Progeria; Protein Precursors; Pyridines; Umbilical Cord; Umbilical Veins; Zoledronic Acid | 2014 |
Evaluation of antitumor effect of zoledronic acid entrapped in folate-linked liposome for targeting to tumor-associated macrophages.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Diphosphonates; Female; Folic Acid; Humans; Imidazoles; KB Cells; Liposomes; Macrophages; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Neovascularization, Pathologic; Tumor Cells, Cultured; Zoledronic Acid | 2015 |
The effects of zoledronate on monocyte-derived dendritic cells from melanoma patients differ depending on the clinical stage of the disease.
Topics: Cell Differentiation; Cell Proliferation; Cells, Cultured; Dendritic Cells; Diphosphonates; Disease Progression; Endocytosis; Female; Humans; Imidazoles; Lipopolysaccharide Receptors; Lymphocyte Activation; Male; Melanoma; Neovascularization, Pathologic; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Helper-Inducer; Tumor Microenvironment; Zoledronic Acid | 2014 |
Rac1/Pak1/p38/MMP-2 Axis Regulates Angiogenesis in Ovarian Cancer.
Topics: Albumins; Animals; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Diphosphonates; Female; High-Throughput Screening Assays; Humans; Imidazoles; Immunohistochemistry; Matrix Metalloproteinase 2; Mice; Mice, Nude; Neovascularization, Pathologic; Ovarian Neoplasms; p21-Activated Kinases; p38 Mitogen-Activated Protein Kinases; Paclitaxel; rac1 GTP-Binding Protein; Signal Transduction; Transfection; Xenograft Model Antitumor Assays; Zoledronic Acid | 2015 |
Basal and therapy-driven hypoxia-inducible factor-1α confers resistance to endocrine therapy in estrogen receptor-positive breast cancer.
Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Diphosphonates; Drug Resistance, Neoplasm; Estradiol; Estrogens; Female; Fulvestrant; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazoles; Letrozole; MAP Kinase Signaling System; Mice; Mice, Nude; Neoadjuvant Therapy; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Neovascularization, Pathologic; Nitriles; Postmenopause; Receptors, Estrogen; RNA Interference; RNA, Small Interfering; Transcription, Genetic; Treatment Outcome; Triazoles; Xenograft Model Antitumor Assays; Zoledronic Acid | 2015 |
Zoledronic acid impairs stromal reactivity by inhibiting M2-macrophages polarization and prostate cancer-associated fibroblasts.
Topics: Cancer-Associated Fibroblasts; Cell Line, Tumor; Cell Movement; Diphosphonates; Humans; Imidazoles; Macrophage Activation; Macrophages; Male; Mevalonic Acid; Neoplasm Metastasis; Neovascularization, Pathologic; Phenotype; Prostatic Neoplasms; rhoA GTP-Binding Protein; Stromal Cells; Tumor Microenvironment; Zoledronic Acid | 2017 |
KRAS-mutation status dependent effect of zoledronic acid in human non-small cell cancer preclinical models.
Topics: A549 Cells; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Movement; Cell Proliferation; Cisplatin; Diphosphonates; Dose-Response Relationship, Drug; Genetic Predisposition to Disease; Humans; Imidazoles; Lung Neoplasms; Male; Mice, Inbred BALB C; Mice, SCID; Mutation; Neoplasm Invasiveness; Neovascularization, Pathologic; Phenotype; Proto-Oncogene Proteins p21(ras); Signal Transduction; Tumor Burden; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays; Zoledronic Acid | 2016 |
Zoledronic acid alters hematopoiesis and generates breast tumor-suppressive bone marrow cells.
Topics: Animals; Bone and Bones; Bone Density Conservation Agents; Bone Marrow; Bone Marrow Cells; Breast Neoplasms; Cell Line, Tumor; Colony-Forming Units Assay; Diphosphonates; Disease Models, Animal; Extracellular Matrix; Female; Hematopoiesis; Hematopoietic Stem Cells; Humans; Imidazoles; Leukocyte Count; Mice; Neovascularization, Pathologic; Osteoblasts; Osteoclasts; X-Ray Microtomography; Zoledronic Acid | 2017 |
Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway.
Topics: Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Diphosphonates; Female; Genes, erbB-2; Imidazoles; Interferon-gamma; Interleukin-10; Macrophages; Mammary Glands, Animal; Mammary Neoplasms, Animal; Metabolic Networks and Pathways; Mevalonic Acid; Mice; Mice, Inbred BALB C; Mice, Transgenic; Neovascularization, Pathologic; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Protein Prenylation; Vascular Endothelial Growth Factor A; Zoledronic Acid | 2010 |
Bortezomib and zoledronic acid on angiogenic and vasculogenic activities of bone marrow macrophages in patients with multiple myeloma.
Topics: Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Boronic Acids; Bortezomib; Cell Adhesion; Cell Movement; Cell Proliferation; Diphosphonates; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Imidazoles; Macrophages; Male; Middle Aged; Multiple Myeloma; Neovascularization, Pathologic; NF-kappa B; Phosphorylation; Pyrazines; Vascular Endothelial Growth Factor Receptor-2; Zoledronic Acid | 2010 |
Nitrogen-containing bisphosphonates can inhibit angiogenesis in vivo without the involvement of farnesyl pyrophosphate synthase.
Topics: Animals; Cell Proliferation; Cell Survival; Cells, Cultured; Chick Embryo; Chorioallantoic Membrane; Diphosphonates; Endothelial Cells; Etidronic Acid; Geranyltranstransferase; Humans; Imidazoles; Male; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Risedronic Acid; Zoledronic Acid | 2011 |
Nanotechnologies to use bisphosphonates as potent anticancer agents: the effects of zoledronic acid encapsulated into liposomes.
Topics: Animals; Antineoplastic Agents; Bone Density Conservation Agents; Cell Line, Tumor; Cell Proliferation; Diphosphonates; Drug Delivery Systems; Humans; Imidazoles; Liposomes; Male; Mice; Mice, Nude; Multiple Myeloma; Neovascularization, Pathologic; Prostate; Prostatic Neoplasms; Zoledronic Acid | 2011 |
Zoledronic acid inhibits vasculogenic mimicry in murine osteosarcoma cell line in vitro.
Topics: Angiogenesis Inhibitors; Animals; Bone Density Conservation Agents; Bone Neoplasms; Cell Line, Tumor; Diphosphonates; Imidazoles; Mice; Microvilli; Neovascularization, Pathologic; Organ Culture Techniques; Osteosarcoma; Protein Transport; rhoA GTP-Binding Protein; Zoledronic Acid | 2011 |
Combination therapy inhibits development and progression of mammary tumours in immunocompetent mice.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Density Conservation Agents; Cell Proliferation; Diphosphonates; Disease Models, Animal; Disease Progression; Doxorubicin; Female; Imidazoles; Immunocompetence; Macrophages; Male; Mammary Neoplasms, Experimental; Mice; Neoplasm Metastasis; Neoplasm Staging; Neovascularization, Pathologic; Zoledronic Acid | 2012 |
Evaluation of the in vitro and in vivo antiangiogenic effects of denosumab and zoledronic acid.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Denosumab; Diphosphonates; Female; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; RANK Ligand; Xenograft Model Antitumor Assays; Zoledronic Acid | 2012 |
Zoledronic acid treatment of 5T2MM-bearing mice inhibits the development of myeloma bone disease: evidence for decreased osteolysis, tumor burden and angiogenesis, and increased survival.
Topics: Animals; Bone Density; Diphosphonates; Disease-Free Survival; Imidazoles; Mice; Mice, Inbred C57BL; Multiple Myeloma; Neovascularization, Pathologic; Zoledronic Acid | 2003 |
Is hypocalcemia during therapy with zoledronic acid or other bisphosphonates beneficial to cancer patients?
Topics: Angiogenesis Inhibitors; Calcium; Diphosphonates; Humans; Hypocalcemia; Imidazoles; Models, Biological; Neoplasms; Neovascularization, Pathologic; Treatment Outcome; Zoledronic Acid | 2004 |
An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis.
Topics: Angiogenesis Inhibitors; Animals; Cell Movement; Diphosphonates; Enzyme Activation; Female; Humans; Imidazoles; Macrophage Activation; Macrophages; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Transgenic; Neovascularization, Pathologic; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms; Vascular Endothelial Growth Factors; Zoledronic Acid | 2004 |
Zoledronic acid-related angiogenesis modifications and survival in advanced breast cancer patients.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Cohort Studies; Diphosphonates; Female; Humans; Imidazoles; Interferon-gamma; Neovascularization, Pathologic; Prospective Studies; Survival Rate; Vascular Endothelial Growth Factor A; Zoledronic Acid | 2005 |
Zoledronic acid and angiogenesis.
Topics: Bone Density Conservation Agents; Diphosphonates; Humans; Imidazoles; Neoplasms; Neovascularization, Pathologic; Zoledronic Acid | 2007 |
Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma.
Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Colony-Forming Units Assay; Diphosphonates; Female; Hematopoiesis; Imidazoles; Immune Tolerance; Immunotherapy; Macrophages; Male; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Myeloid Cells; Neovascularization, Pathologic; Receptor, ErbB-2; Stromal Cells; Vascular Endothelial Growth Factor A; Zoledronic Acid | 2007 |
Zoledronic acid affects over-angiogenic phenotype of endothelial cells in patients with multiple myeloma.
Topics: Adult; Aged; Base Sequence; Blotting, Western; Culture Media, Conditioned; Diphosphonates; DNA Primers; Enzyme-Linked Immunosorbent Assay; Female; Humans; Imidazoles; Lovastatin; Male; Middle Aged; Multiple Myeloma; Neovascularization, Pathologic; Phenotype; Receptors, Vascular Endothelial Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; Vascular Endothelial Growth Factor A; Zoledronic Acid | 2007 |
Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: role of bone marrow-derived myelomonocytic cells.
Topics: Animals; Antineoplastic Agents; Bone Marrow Cells; Bone Marrow Transplantation; CD11b Antigen; Diphosphonates; Endothelial Cells; Imidazoles; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Melanoma, Experimental; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Myeloid Cells; Neoplasms, Experimental; Neovascularization, Pathologic; Protease Inhibitors; Signal Transduction; Stem Cells; Subcutaneous Tissue; Time Factors; Zoledronic Acid | 2008 |
Zoledronic acid is effective against experimental malignant pleural effusion.
Topics: Animals; Apoptosis; Capillary Permeability; Carcinoma, Lewis Lung; Cell Line, Tumor; Cell Proliferation; Diphosphonates; Imidazoles; Leukocytes, Mononuclear; Lung Neoplasms; Macrophages; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neovascularization, Pathologic; Pleural Effusion, Malignant; Pleural Neoplasms; Zoledronic Acid | 2008 |