zithromax has been researched along with Prostatic-Hyperplasia* in 1 studies
1 other study(ies) available for zithromax and Prostatic-Hyperplasia
Article | Year |
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Concentration of azithromycin in human prostatic tissue.
Prostatic tissue was obtained from 36 patients at two study locations and assayed for azithromycin by HPLC or bioassay. The mean concentration of azithromycin in human prostatic tissue (2.54 micrograms/ml) 14 h after 500 mg oral dosing (two 250 mg doses 12 h apart) was much greater than plasma concentrations (less than or equal to 0.1 micrograms/ml). Azithromycin was slowly eliminated from prostatic tissue (half-life 60 h) and a mean concentration of 0.62 micrograms/ml remained 137 h after dosing. Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Azithromycin; Chromatography, High Pressure Liquid; Erythromycin; Half-Life; Humans; Male; Prostate; Prostatectomy; Prostatic Hyperplasia; Prostatic Neoplasms; Time Factors | 1991 |