zithromax and Granulomatous-Mastitis

A 37-year-old immunocompetent woman was evaluated for progressive swelling of her left breast. Magnetic resonance imaging (MRI) showed multiple hypo-intense solid lesions and could not exclude breast cancer. Tissue biopsy was suggestive of granulomatous mastitis without any evidence of malignancy. Culture of the specimen in brain heart infusion broth grew Rhodococcus equi. The patient responded well to combination therapy with ciprofloxacin and azithromycin, and the lesions regressed in follow-up MRI. To the best of our knowledge, this is the first report of R. equi granulomatous mastitis. Accurate identification of this rare pathogen is necessary to provide appropriate treatment in granulomatous mastitis.

Topics: Actinomycetales Infections; Adult; Anti-Bacterial Agents; Azithromycin; Biopsy, Fine-Needle; Ciprofloxacin; Drug Therapy, Combination; Female; Granulomatous Mastitis; Humans; Immunocompetence; Magnetic Resonance Imaging; Radiography; Rhodococcus equi; Treatment Outcome