Page last updated: 2024-08-24

ziprasidone and Long QT Syndrome

ziprasidone has been researched along with Long QT Syndrome in 41 studies

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	26 (63.41)	29.6817
2010's	14 (34.15)	24.3611
2020's	1 (2.44)	2.80

Authors

Authors	Studies
Chen, XL; Kang, J; Kongsamut, S; Rampe, D; Roehr, J	1
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M	1
Bordet, C; Galinier, M; Garcia, P; Montastruc, F; Salvo, F; Sommet, A; Touafchia, A	1
Erbas, O; Yilmaz, M	1
Achtyes, ED; Buckley, P; Bustillo, JR; Citrome, L; Gil, R; Goff, DC; Macklin, EA; Manschreck, TC; McEvoy, JP; Mech, AW	1
Hamilton, JB; Heaton, C; Lannan, R; Lavedan, C; Licamele, L; Mack, K; Polymeropoulos, MH; Volpi, S; Wolfgang, CD	1
Dressing, H; Krumm, B; Kuwilsky, A; Zink, M	1
Lin, YL; Tsai, GF; Wu, YC	1
Alipour, A; Cruz, R; Lott, RS	1
Strawn, JR; Tambyraja, R	1
D'Agostino, RB; Eng, SM; Faich, G; Kane, JM; Reynolds, RF; Ruskin, J; Strom, BL	1
Stroup, TS	1
Citrome, L	1
Correll, CU; Figen, V; Kane, JM; Lops, JD; Malhotra, AK; Manu, P	1
Nielsen, J	1
Mycyk, MB; Witsil, JC; Zell-Kanter, M	1
Hasnain, M; Vieweg, WV	1
Camm, AJ; Kane, JM; Karayal, ON; Kolluri, S; Meltzer, H; Miceli, J; O'Gorman, C; Tensfeldt, T	1
Mencacci, C	1
Hochfeld, M; Meng, X; Potkin, SG; Preskorn, S	1
Kelly, DL; Love, RC	1
Biswas, AK; Mayes, KL; Morris-Kukoski, CL; Zabrocki, LA	2
Taylor, D	1
Teich, J	1
Jaffe, R; Leavitt, R; Wind, T	1
Martel, ML	1
Levy, WO; Nunez, C; Robichaux-Keene, NR	1
Minov, C	1
Finzel, M; Fric, M; Laux, G	1
Baldessarini, RJ; Berry, JM; Centorrino, F; Fogarty, KV; Kidwell, JE; MacLean, E; Salvatore, P	1
Blair, J; Martin, A; Scahill, L; State, M	1
Brown, FW; Greco, KE; Tune, LE; Van Horn, WA	1
Chappell, P; Loebel, A; Miceli, J; Siu, C	1
Scott, LJ; Swainston Harrison, T	1
Hoffman, RS; Manini, AF; Nelson, LS; Raspberry, D	1
D'Agostino, RB; Eng, SM; Faich, GA; Kane, JM; Reynolds, RF; Ruskin, JN; Strom, BL	1
Bentley, ML; Biscardi, FH; Butcher, C; Levitov, A	1
Caley, CF; Cooper, CK	1
Crismon, L; Dorson, PG; Patel, NC; Sierk, P	1
Taylor, DM	1

Reviews

6 review(s) available for ziprasidone and Long QT Syndrome

Article	Year
Drug safety evaluation of ziprasidone. Expert opinion on drug safety, 2011, Volume: 10, Issue:3 Topics: Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic; Drug-Related Side Effects and Adverse Reactions; Humans; Long QT Syndrome; Piperazines; Schizophrenia; Thiazoles	2011
Ziprasidone and the corrected QT interval: a comprehensive summary of clinical data. CNS drugs, 2012, Apr-01, Volume: 26, Issue:4 Topics: Administration, Oral; Adult; Antipsychotic Agents; Bipolar Disorder; Child; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Clinical Trials, Phase IV as Topic; Dose-Response Relationship, Drug; Electrocardiography; Humans; Long QT Syndrome; Piperazines; Randomized Controlled Trials as Topic; Schizophrenia; Thiazoles	2012
Ziprasidone and the QTc interval: pharmacokinetic and pharmacodynamic considerations. Psychopharmacology bulletin, 2001,Autumn, Volume: 35, Issue:4 Topics: Animals; Antipsychotic Agents; Electrocardiography; Humans; Long QT Syndrome; Piperazines; Thiazoles	2001
Ziprasidone in the management of schizophrenia : the QT interval issue in context. CNS drugs, 2003, Volume: 17, Issue:6 Topics: Antipsychotic Agents; Electrocardiography; Female; Humans; Long QT Syndrome; Male; Piperazines; Risk Assessment; Risk Factors; Schizophrenia; Sex Factors; Thiazoles; Torsades de Pointes	2003
Ziprasidone: a review of its use in schizophrenia and schizoaffective disorder. CNS drugs, 2006, Volume: 20, Issue:12 Topics: Antipsychotic Agents; Area Under Curve; Humans; Injections, Intramuscular; Long QT Syndrome; Piperazines; Psychotic Disorders; Schizophrenia; Tablets; Thiazoles; Treatment Outcome	2006
Ziprasidone: the fifth atypical antipsychotic. The Annals of pharmacotherapy, 2002, Volume: 36, Issue:5 Topics: Acute Disease; Antipsychotic Agents; Basal Ganglia Diseases; Body Weight; Headache; Humans; Injections, Intramuscular; Long QT Syndrome; Nausea; Piperazines; Randomized Controlled Trials as Topic; Schizophrenia; Thiazoles; Treatment Outcome; Weight Gain	2002

Trials

9 trial(s) available for ziprasidone and Long QT Syndrome

Article	Year
High-dose oral ziprasidone versus conventional dosing in schizophrenia patients with residual symptoms: the ZEBRAS study. Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:4 Topics: Adult; Antipsychotic Agents; Blood Pressure; Female; Humans; Long QT Syndrome; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Thiazoles; Time Factors; Treatment Outcome; United States	2013
Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia. Molecular psychiatry, 2009, Volume: 14, Issue:11 Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Carrier Proteins; CELF Proteins; Cytoskeletal Proteins; Double-Blind Method; Electrocardiography; Female; Follow-Up Studies; Gene Frequency; Genome-Wide Association Study; Genotype; Humans; Intracellular Signaling Peptides and Proteins; Isoxazoles; Linear Models; Linkage Disequilibrium; Long QT Syndrome; Male; Middle Aged; Neuregulins; Organic Anion Transporters; Pharmacogenetics; Phosphoproteins; Phosphotransferases (Alcohol Group Acceptor); Piperazines; Piperidines; Polymorphism, Single Nucleotide; RNA-Binding Proteins; Schizophrenia; Thiazoles; Young Adult	2009
Efficacy and tolerability of ziprasidone versus risperidone as augmentation in patients partially responsive to clozapine: a randomised controlled clinical trial. Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:3 Topics: Adolescent; Adult; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Female; Humans; Long QT Syndrome; Male; Middle Aged; Piperazines; Prolactin; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Thiazoles; Treatment Outcome; Young Adult	2009
Comparative mortality associated with ziprasidone and olanzapine in real-world use among 18,154 patients with schizophrenia: The Ziprasidone Observational Study of Cardiac Outcomes (ZODIAC). The American journal of psychiatry, 2011, Volume: 168, Issue:2 Topics: Adult; Antipsychotic Agents; Benzodiazepines; Cause of Death; Cross-Sectional Studies; Death, Sudden, Cardiac; Diabetic Ketoacidosis; Female; Hospitalization; Humans; Incidence; Kaplan-Meier Estimate; Long QT Syndrome; Male; Middle Aged; Myocardial Infarction; Olanzapine; Piperazines; Product Surveillance, Postmarketing; Prospective Studies; Risk; Schizophrenia; Suicide; Thiazoles	2011
Efficacy and tolerability of switching to ziprasidone in italian patients with acute exacerbation of schizophrenia: an open-label trial. Pharmacopsychiatry, 2012, Volume: 45, Issue:6 Topics: Adult; Antipsychotic Agents; Female; Humans; Long QT Syndrome; Male; Middle Aged; Patient Preference; Piperazines; Psychiatric Status Rating Scales; Schizophrenia; Thiazoles	2012
A thorough QTc study of 3 doses of iloperidone including metabolic inhibition via CYP2D6 and/or CYP3A4 and a comparison to quetiapine and ziprasidone. Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:1 Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dibenzothiazepines; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Electrocardiography; Enzyme Inhibitors; Female; Genotype; Heart Rate; Humans; Isoxazoles; Ketoconazole; Linear Models; Long QT Syndrome; Male; Middle Aged; Paroxetine; Pharmacogenetics; Phenotype; Piperazines; Piperidines; Quetiapine Fumarate; Thiazoles; United States; Young Adult	2013
[QTc-interval prolongation in therapy with atypical antipsychotics--results of an open, non-randomized survey]. Psychiatrische Praxis, 2004, Volume: 31 Suppl 1 Topics: Antipsychotic Agents; Electrocardiography; Germany; Hospitalization; Hospitals, Psychiatric; Humans; Long QT Syndrome; Piperazines; Prospective Studies; Psychotic Disorders; Risk Assessment; Thiazoles; Torsades de Pointes	2004
Electrocardiographic changes in children and adolescents treated with ziprasidone: a prospective study. Journal of the American Academy of Child and Adolescent Psychiatry, 2005, Volume: 44, Issue:1 Topics: Adolescent; Antipsychotic Agents; Child; Child Development Disorders, Pervasive; Electrocardiography; Female; Humans; Long QT Syndrome; Male; Obsessive-Compulsive Disorder; Piperazines; Prospective Studies; Psychotic Disorders; Thiazoles; Tourette Syndrome	2005
The Ziprasidone Observational Study of Cardiac Outcomes (ZODIAC): design and baseline subject characteristics. The Journal of clinical psychiatry, 2008, Volume: 69, Issue:1 Topics: Adult; Antipsychotic Agents; Body Mass Index; Dyslipidemias; Female; Glycated Hemoglobin; Humans; Hypertension; Long QT Syndrome; Male; Observation; Piperazines; Prevalence; Research Design; Schizophrenia; Severity of Illness Index; Surveys and Questionnaires; Thiazoles; Triglycerides	2008

Other Studies

26 other study(ies) available for ziprasidone and Long QT Syndrome

Article	Year
A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs. European journal of pharmacology, 2002, Aug-16, Volume: 450, Issue:1 Topics: Animals; Antipsychotic Agents; Cation Transport Proteins; Cell Line; Clinical Trials as Topic; Cricetinae; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Long QT Syndrome; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Trans-Activators; Transcriptional Regulator ERG	2002
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers. Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18 Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2002
Antipsychotics and risk of QT prolongation: a pharmacovigilance study. Psychopharmacology, 2023, Volume: 240, Issue:1 Topics: Amisulpride; Antipsychotic Agents; Humans; Long QT Syndrome; Lurasidone Hydrochloride; Pharmacovigilance	2023
Metoprolol and diltiazem ameliorate ziprasidone-induced prolonged corrected QT interval in rats. Toxicology and industrial health, 2015, Volume: 31, Issue:12 Topics: Adrenergic beta-1 Receptor Antagonists; Anesthesia; Animals; Anti-Arrhythmia Agents; Antipsychotic Agents; Calcium Channel Blockers; Diltiazem; Electrocardiography; Heart; Injections, Intraperitoneal; Long QT Syndrome; Male; Metoprolol; Piperazines; Random Allocation; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Thiazoles	2015
Electrocardiographic monitoring for QT prolongation in patients treated with ziprasidone--a claims database approach. Pharmacoepidemiology and drug safety, 2009, Volume: 18, Issue:9 Topics: Adult; Antipsychotic Agents; Databases, Factual; Electrocardiography; Female; Humans; Long QT Syndrome; Male; Middle Aged; Piperazines; Retrospective Studies; Taiwan; Thiazoles; Young Adult	2009
Torsade de pointes after ziprasidone overdose with coingestants. Journal of clinical psychopharmacology, 2010, Volume: 30, Issue:1 Topics: Antidepressive Agents, Second-Generation; Antipsychotic Agents; Anxiety Disorders; Bipolar Disorder; Drug Overdose; Female; Humans; Long QT Syndrome; Middle Aged; Piperazines; Thiazoles; Torsades de Pointes	2010
Third degree heart block following intramuscular ziprasidone. Schizophrenia research, 2011, Volume: 125, Issue:2-3 Topics: Aged; Alzheimer Disease; Antipsychotic Agents; Bradycardia; Cardiopulmonary Resuscitation; Dementia, Vascular; Dose-Response Relationship, Drug; Female; Heart Block; Hospitalization; Humans; Injections, Intramuscular; Long QT Syndrome; Piperazines; Schizophrenia, Paranoid; Thiazoles	2011
What can large simple trials do for psychiatry? The American journal of psychiatry, 2011, Volume: 168, Issue:2 Topics: Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Death, Sudden, Cardiac; Humans; Long QT Syndrome; Multicenter Studies as Topic; Piperazines; Product Surveillance, Postmarketing; Randomized Controlled Trials as Topic; Risk Factors; Schizophrenia; Thiazoles	2011
QT interval duration and dispersion in children and adolescents treated with ziprasidone. The Journal of clinical psychiatry, 2011, Volume: 72, Issue:6 Topics: Adolescent; Antipsychotic Agents; Child; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Rate; Humans; Long QT Syndrome; Male; Piperazines; Potassium; Thiazoles; Torsades de Pointes	2011
The safety of atypical antipsychotics: does QTc provide all the answers? Expert opinion on drug safety, 2011, Volume: 10, Issue:3 Topics: Antipsychotic Agents; Humans; Long QT Syndrome; Piperazines; Thiazoles; Torsades de Pointes	2011
Single-dose ziprasidone associated with QT interval prolongation. The American journal of emergency medicine, 2012, Volume: 30, Issue:5 Topics: Antipsychotic Agents; Electrocardiography; Emergency Service, Hospital; Humans; Long QT Syndrome; Male; Middle Aged; Piperazines; Psychomotor Agitation; Thiazoles	2012
Question regarding ziprasidone and QTc interval prolongation in the ZODIAC study. The American journal of psychiatry, 2011, Volume: 168, Issue:6 Topics: Adult; Antipsychotic Agents; Female; Humans; Long QT Syndrome; Male; Piperazines; Schizophrenia; Thiazoles; Treatment Outcome	2011
Cardiotoxicity associated with intentional ziprasidone and bupropion overdose. Journal of toxicology. Clinical toxicology, 2003, Volume: 41, Issue:1 Topics: Adult; Anti-Arrhythmia Agents; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Bupropion; Drug Overdose; Electrocardiography; Heart Diseases; Humans; Hydrogen-Ion Concentration; Long QT Syndrome; Male; Piperazines; Suicide, Attempted; Thiazoles	2003
Cardiotoxicity associated with intentional ziprasidone and bupropion overdose. Journal of toxicology. Clinical toxicology, 2003, Volume: 41, Issue:2 Topics: Adolescent; Anti-Arrhythmia Agents; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Bupropion; Consciousness; Depressive Disorder, Major; Drug Overdose; Electrocardiography; Heart Diseases; Humans; Hydrogen-Ion Concentration; Lidocaine; Long QT Syndrome; Male; Piperazines; Suicide, Attempted; Thiazoles	2003
Side effects of ziprasidone. The American journal of psychiatry, 2003, Volume: 160, Issue:7 Topics: Antipsychotic Agents; Female; Humans; Hypokalemia; Long QT Syndrome; Magnesium; Middle Aged; Mood Disorders; Piperazines; Thiazoles; Water-Electrolyte Imbalance	2003
QTc prolongation in multiple drug overdose. Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:3 Topics: Adult; Bupropion; Drug Overdose; Fluoxetine; Humans; Long QT Syndrome; Male; Piperazines; Psychotic Disorders; Thiazoles; Valproic Acid	2004
Ziprasidone for sedation of the agitated ED patient. The American journal of emergency medicine, 2004, Volume: 22, Issue:3 Topics: Antipsychotic Agents; Droperidol; Drug Labeling; Emergency Treatment; Humans; Long QT Syndrome; Piperazines; Practice Guidelines as Topic; Psychomotor Agitation; Thiazoles; Torsades de Pointes; United States; United States Food and Drug Administration	2004
No significant QTc interval changes with high-dose ziprasidone: a case series. Journal of psychiatric practice, 2004, Volume: 10, Issue:4 Topics: Adult; Dose-Response Relationship, Drug; Electrocardiography; Female; Humans; Long QT Syndrome; Male; Middle Aged; Piperazines; Retrospective Studies; Serotonin Antagonists; Thiazoles	2004
[Risk of QTc prolongation due to combination of ziprasidone and quetiapine]. Psychiatrische Praxis, 2004, Volume: 31 Suppl 1 Topics: Acute Disease; Aged; Antipsychotic Agents; Dibenzothiazepines; Drug Interactions; Drug Therapy, Combination; Electrocardiography; Hallucinations; Humans; Long QT Syndrome; Male; Piperazines; Quetiapine Fumarate; Schizophrenia, Paranoid; Thiazoles	2004
Ziprasidone: first year experience in a hospital setting. Journal of psychiatric practice, 2004, Volume: 10, Issue:6 Topics: Adult; Antipsychotic Agents; Depressive Disorder; Electrocardiography; Female; Hospitalization; Humans; Inpatients; Length of Stay; Long QT Syndrome; Male; Middle Aged; Mood Disorders; Piperazines; Retrospective Studies; Schizophrenia; Thiazoles; Treatment Outcome	2004
A retrospective study of the safety of intramuscular ziprasidone in agitated elderly patients. The Journal of clinical psychiatry, 2005, Volume: 66, Issue:7 Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Arrhythmias, Cardiac; Dementia; Electrocardiography; Female; Haloperidol; Humans; Injections, Intramuscular; Long QT Syndrome; Male; Middle Aged; Piperazines; Psychomotor Agitation; Retrospective Studies; Risk Factors; Thiazoles; Torsades de Pointes	2005
Electrocardiographic changes with ziprasidone. Journal of the American Academy of Child and Adolescent Psychiatry, 2006, Volume: 45, Issue:6 Topics: Adolescent; Antipsychotic Agents; Child; Data Interpretation, Statistical; Electrocardiography; Female; Humans; Long QT Syndrome; Male; Piperazines; Psychotic Disorders; Research Design; Selection Bias; Thiazoles; Tourette Syndrome	2006
QT prolongation and Torsades de Pointes following overdose of ziprasidone and amantadine. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2007, Volume: 3, Issue:4 Topics: Adult; Amantadine; Analgesics, Non-Narcotic; Antipsychotic Agents; Drug Overdose; Drug Therapy, Combination; Electrocardiography; Fatal Outcome; Female; Humans; Ibuprofen; Long QT Syndrome; Piperazines; Suicide, Attempted; Thiazoles; Torsades de Pointes	2007
Inadvertent administration of intravenous ziprasidone leading to bradycardia and QT interval prolongation. The Annals of pharmacotherapy, 2008, Volume: 42, Issue:6 Topics: Adult; Antipsychotic Agents; Bradycardia; Electrocardiography; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Long QT Syndrome; Medication Errors; Piperazines; Thiazoles	2008
Experience with ziprasidone. Journal of the American Academy of Child and Adolescent Psychiatry, 2002, Volume: 41, Issue:5 Topics: Adolescent; Antipsychotic Agents; Contraindications; Depressive Disorder, Major; Drug Evaluation; Electrocardiography; Female; Humans; Long QT Syndrome; Male; Piperazines; Psychotic Disorders; Thiazoles	2002
Prolongation of QTc interval and antipsychotics. The American journal of psychiatry, 2002, Volume: 159, Issue:6 Topics: Antipsychotic Agents; Death, Sudden, Cardiac; Drug Administration Schedule; Drug Labeling; Drug Monitoring; Haloperidol; Humans; Long QT Syndrome; Piperazines; Risperidone; Thiazoles	2002