zinostatin has been researched along with Plasmacytoma* in 2 studies
2 other study(ies) available for zinostatin and Plasmacytoma
Article | Year |
---|---|
[Experimental study on immunochemotherapy using schizophyllan].
Immunochemotherapy with schizophyllan (SPG) combined with chemotherapeutic agents was evaluated in two syngeneic tumor-C3H/He mouse systems. The administration of SPG alone caused a significant growth inhibition of MM 46 mammary carcinoma, the highest therapeutic effect being obtained by SPG given at the advanced stage of tumors. When combined with neocarzinostatin given 7-times every other day the simultaneous administration of SPG produced an optimal response to that therapy. In X-5563 plasmacytoma, SPG alone was ineffective. However, when combined with mitomycin C given with 1 to 5-days interval, the concurrent administration of SPG prolonged significantly the life-span of the tumor-bearing mice. These results indicated that the simultaneous administration of SPG and antitumor drugs may be a useful application method for immunochemotherapy of experimental tumors. Topics: Adjuvants, Immunologic; Animals; Glycosaminoglycans; Macrophage Activation; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Mitomycin; Mitomycins; Neoplasms, Experimental; Plasmacytoma; Sizofiran; T-Lymphocytes; Zinostatin | 1982 |
Biological activity of the antitumor protein neocarzinostatin coupled to a monoclonal antibody by N-succinimidyl 3-(2-pyridyldithio)-propionate.
Topics: Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Bacillus subtilis; Clone Cells; DNA, Viral; Indicators and Reagents; Mice; Mice, Inbred BALB C; Plasmacytoma; Pyridines; Succinimides; T-Phages; Zinostatin | 1981 |