zinostatin and Neoplasm-Seeding

zinostatin has been researched along with Neoplasm-Seeding* in 2 studies

Reviews

1 review(s) available for zinostatin and Neoplasm-Seeding

Article	Year
[Subarachnoid dissemination of the brain tumor cells (author's transl)]. No shinkei geka. Neurological surgery, 1980, Volume: 8, Issue:12 Topics: Animals; Brain Neoplasms; Dogs; Glioma; Humans; Meningeal Neoplasms; Meningioma; Neoplasm Metastasis; Neoplasm Seeding; Rabbits; Rats; Subarachnoid Space; Zinostatin	1980

Other Studies

1 other study(ies) available for zinostatin and Neoplasm-Seeding

Article	Year
[Efficacy of intra-peritoneal and intra-venous injection of monoclonal antibody A7-NCS conjugates against peritoneal dissemination of the gastric cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:11 The monoclonal antibody A7 (Mab A7) against human colonic cancer also reacts with human gastric cancer at a high rate. We produced a conjugate of neocarzinostatin (NCS) with Mab A7 (A7-NCS). The in vitro anticancer effect of A7-NCS on the antigen-positive human gastric cancer cell line MKN45 was stronger than that of free NCS. Nude mice models of peritoneal dissemination were established by the intra-peritoneal inoculation of MKN45. These models were divided into three groups. The anticancer effect observed in the group that received the intra peritoneal injection of A7-NCS was superior to that observed in the group that received the intra-venous injection and the group that received no treatment. In conclusion, the intra-peritoneal injection of A7-NCS was a useful treatment method for the peritoneal dissemination of gastric cancer. Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antigens, Neoplasm; Cell Line, Tumor; Humans; Infusions, Parenteral; Injections, Intravenous; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Seeding; Peritoneal Neoplasms; Stomach Neoplasms; Zinostatin	2004

Article

Year

[Efficacy of intra-peritoneal and intra-venous injection of monoclonal antibody A7-NCS conjugates against peritoneal dissemination of the gastric cancer].

Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:11

The monoclonal antibody A7 (Mab A7) against human colonic cancer also reacts with human gastric cancer at a high rate. We produced a conjugate of neocarzinostatin (NCS) with Mab A7 (A7-NCS). The in vitro anticancer effect of A7-NCS on the antigen-positive human gastric cancer cell line MKN45 was stronger than that of free NCS. Nude mice models of peritoneal dissemination were established by the intra-peritoneal inoculation of MKN45. These models were divided into three groups. The anticancer effect observed in the group that received the intra peritoneal injection of A7-NCS was superior to that observed in the group that received the intra-venous injection and the group that received no treatment. In conclusion, the intra-peritoneal injection of A7-NCS was a useful treatment method for the peritoneal dissemination of gastric cancer.

Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antigens, Neoplasm; Cell Line, Tumor; Humans; Infusions, Parenteral; Injections, Intravenous; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Seeding; Peritoneal Neoplasms; Stomach Neoplasms; Zinostatin

2004