zimeldine has been researched along with Mood-Disorders* in 2 studies
1 trial(s) available for zimeldine and Mood-Disorders
| Article | Year |
|---|---|
Evaluation of role of the biogenic amines in affective illness: a clinical strategy.
Topics: Antidepressive Agents; Biogenic Amines; Brompheniramine; Clinical Trials as Topic; Desipramine; Humans; Mood Disorders; Zimeldine | 1982 |
1 other study(ies) available for zimeldine and Mood-Disorders
| Article | Year |
|---|---|
The research and development of a 5-HT selective reuptake blocker. Preclinical aspects.
The preclinical development of zimeldine according to the 5-HT (serotonin) hypothesis is briefly reviewed. Zimeldine is a selective 5-HT reuptake inhibitor based on the "chemical lead" of brompheniramine--an antihistamine with some 5-HT reuptake inhibitory properties. By chemical manipulation of the position of the pyridine ring in brompheniramine and the stereochemistry of the side chain, a selective 5-HT reuptake inhibitor has been developed. Topics: Animals; Chemistry, Pharmaceutical; Drug Evaluation, Preclinical; Humans; Mood Disorders; Norepinephrine; Serotonin; Synapses; Zimeldine | 1983 |