zileuton has been researched along with Brain Ischemia in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Cui, E; Du, L; Du, S; Jiang, X; Li, J; Ma, X; Qian, S; Wang, H | 1 |
| Chen, W; Han, H; Li, C; Wei, E; Zhang, L; Zhang, X; Zhao, J | 1 |
| Chen, CM; Liang, RS; Shi, SS; Tu, XK; Wang, CH; Yang, WZ; Zhang, HB | 1 |
| Chen, CM; Shi, SS; Tu, XK; Wang, CH; Yang, WZ | 1 |
| Chen, CM; Jin, CD; Shi, SS; Tu, XK; Wang, CH; Wen, S; Yang, WZ; Yang, YK; Zhang, YL | 1 |
| Fang, SH; Huang, XQ; Lin, KN; Lu, YB; Wei, EQ; Zhang, WP | 1 |
6 other study(ies) available for zileuton and Brain Ischemia
| Article | Year |
|---|---|
Design and synthesis of novel indole and indazole-piperazine pyrimidine derivatives with anti-inflammatory and neuroprotective activities for ischemic stroke treatment.
Topics: Animals; Anti-Inflammatory Agents; Brain Ischemia; Cyclooxygenase 2; Disease Models, Animal; Indazoles; Indoles; Ischemic Stroke; Lipopolysaccharides; Mice; Microglia; Neuroprotection; Neuroprotective Agents; Piperazine; Pyrimidines; Rats; Stroke; Tumor Necrosis Factor-alpha | 2022 |
[Expression of 5-lipoxygenase in hippocampal CA1 neuronal damage following global cerebral ischemia in rats].
Topics: Animals; Arachidonate 5-Lipoxygenase; Brain Ischemia; CA1 Region, Hippocampal; Disease Models, Animal; Hydroxyurea; Lipoxygenase Inhibitors; Male; Neurons; Rats; Rats, Sprague-Dawley | 2013 |
5-LOX Inhibitor Zileuton Reduces Inflammatory Reaction and Ischemic Brain Damage Through the Activation of PI3K/Akt Signaling Pathway.
Topics: Animals; Arachidonate 5-Lipoxygenase; Brain; Brain Ischemia; Hydroxyurea; Infarction, Middle Cerebral Artery; Inflammation; Lipoxygenase Inhibitors; Male; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction | 2016 |
5-lipoxygenase inhibitor zileuton attenuates ischemic brain damage: involvement of matrix metalloproteinase 9.
Topics: Animals; Arachidonate 5-Lipoxygenase; Body Water; Brain; Brain Edema; Brain Ischemia; Dose-Response Relationship, Drug; Down-Regulation; Hydroxyurea; Infarction, Middle Cerebral Artery; Lipoxygenase Inhibitors; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2009 |
Zileuton reduces inflammatory reaction and brain damage following permanent cerebral ischemia in rats.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Brain; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Encephalitis; Enzyme-Linked Immunosorbent Assay; Hydroxyurea; Immunohistochemistry; Interleukin-1beta; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Malondialdehyde; Neuroprotective Agents; Neutrophil Infiltration; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxidase; Rats; Rats, Sprague-Dawley; Time Factors; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2010 |
Nuclear translocation of cysteinyl leukotriene receptor 1 is involved in oxygen-glucose deprivation-induced damage to endothelial cells.
Topics: Apoptosis; Brain Ischemia; Cell Culture Techniques; Cell Hypoxia; Cell Line; Cell Membrane; Cell Nucleus; Cell Survival; Chromones; Endothelial Cells; Glucose; Humans; Hydroxyurea; Ligands; Models, Biological; Nuclear Localization Signals; Oxygen; Protein Transport; Receptors, Leukotriene | 2012 |