Page last updated: 2024-08-24

zileuton and Asthma

zileuton has been researched along with Asthma in 80 studies

Research

Studies (80)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	42 (52.50)	18.2507
2000's	30 (37.50)	29.6817
2010's	7 (8.75)	24.3611
2020's	1 (1.25)	2.80

Authors

Authors	Studies
Kreft, AF; Musser, JH	1
Augert, G; Cottin, M; Demonchaux, P; Dupassieux, P; Jasserand, D; Lenoir, P; Paris, D; Peck, MJ	1
Andersson, U; Andreasson, T; Bergström, EL; Björkstrand, E; Bonn, B; Chang, HF; Chapman, D; Davis, AM; Ek, M; Glader, P; Gordon, E; Jiang, F; Johannesson, P; Käck, H; Lundqvist, AJ; Malmberg, A; Munck Af Rosenschöld, M; Nikitidis, A; Nikitidis, G; Pettersen, A; Ripa, L; Rohman, M; Rönn, R; Swedin, L; Tyrchan, C; Ullah, V; Wågberg, F; Zhou, XH	1
Holguin, F; Nouraie, M; Parikh, A; Thalanayar Muthukrishnan, P	1
Dahlin, A; Irvin, CG; Kubo, M; Lima, JJ; Litonjua, AA; Peters, SP; Qiu, W; Tamari, M; Tantisira, KG; Weiss, ST; Wu, AC	1
Seow, CY; van Eeden, S	1
Chang, FT; Chen, WJ; Liaw, SF; Lin, CC; Lin, MW	1
Dahlin, A; Irvin, CG; Kubo, M; Lima, JJ; Litonjua, A; Peters, SP; Tamari, M; Tantisira, KG	1
Arumugam, PI; Brandt, EB; Carmeliet, P; Eiymo Mwa Mpollo, MS; Hershey, GK; Jonck, B; Kalra, VK; Le Cras, TD; Lindsey, M; Loberg, A; Malik, P; Pillis, D; Ratner, N; Rizvi, T; Shanmukhappa, SK; Tiwari, S; Wills-Karp, M	1
Klanderman, B; Lima, J; Sylvia, J; Tantisira, KG; Weiss, ST	1
Gelb, AF; Shinar, C; Simmons, M; Taylor, CF	1
Kroegel, C	1
Valacer, DJ	1
Dev, A; Leong, AB; Wu, X	1
Jung, A	1
Kemp, JP	1
Blanc, PD; Eisner, MD; Katz, PP; Snyder, L; Yelin, EH	1
Gershwin, ME; Morrissey, BM; Naguwa, S; Vang, K; Watnik, M; Wineinger, J; Ziboh, VA	1
Leru, P	1
Dahlén, SE	1
Capra, V; Cole, DE; Folco, G; Rovati, GE; Sala, A; Thompson, MD	1
Ludington, E; Mehra, P; Simon, RA; Stevenson, DD; White, A	1
Dickerson, KS; Luttermoser, GK; Scow, DT	1
Balter, M; Boulet, LP; Cairns, CB; Löfdahl, CG; O'Connor, BJ; Szczeklik, A	1
Berger, W; Cairns, CB; De Chandt, MT	1
Busse, W; Calhoun, W; Dube, L; Harris, J; Panettieri, R; Peters-Golden, M; Russell, H; Walton-Bowen, K; Wenzel, S	1
Berger, W; Casale, T; Corren, J; Dube, L; Kemp, J; LaVallee, N; Nelson, H; Stepanians, M; Walton-Bowen, K	1
Cameron, CM; Dube, LM; Kasten, LE; Walton-Bowen, K; Watkins, PB	1
Awni, WM; Cohn, J; Drazen, JM; Fischer, AR; Frantz, R; Israel, E; McFadden, CA	1
Ado, VA; Mokronosova, MA; Perlamutrov, IuN	1
Cohn, J; Kaminsky, DA; Martin, RJ; Trudeau, JB; Wenzel, SE; Westcott, JY	1
Ford-Hutchinson, AW	1
Callery, JC; Cohn, J; Drazen, JM; Fischer, AR; Igarashi, Y; Kaliner, MA; Lilly, CM; Rosenberg, MA; Rubin, P; White, MV	1
Busse, W; Cohn, J; Drazen, JM; Fish, J; Grossman, J; Israel, E; Kaiser, HB; Karahalios, P; Kemp, JP; Lanni, C; Ledford, D; Murray, JJ; Pearlman, H; Pierson, W; Rosenthal, R; Rubin, P; Segal, AT; Siegel, SC; Tinkelman, D; Wenzel, S	1
Callery, JC; Cohn, J; Drazen, JM; Fischer, AR; Israel, E; Lilly, CM; Rosenberg, MA; Rubin, P; Shapiro, J	1
Berkenkopf, JW; Carlson, RP; Grimes, D; Kreft, AF; Marinari, LR; Musser, JH; Sturm, RJ; Weichman, BM	1
Cohn, J; Drazen, JM; Dubé, L; Israel, E	1
Busse, WW; McGill, KA	1
Smith, LJ	1
Dubé, LM; Lancaster, J; Liu, MC	1
Tanaka, R	1
Jackson, SK; Larsen, JS	1
Spector, SL; Tan, RA	1
Dubé, LM; Lancaster, JF; Petty, T; Schwartz, HJ; Swanson, LJ	1
Drazen, JM	1
Bootsma, GP; Dekhuijzen, PN; Festen, J; van den Berg, LR; van Herwaarden, CL; Wielders, PL	1
Tan, RA	1
Wenzel, SE	1
Bochenek, G; Boodhoo, TI; Dahlén, B; Dahlén, SE; Dubé, LM; Kumlin, M; Mastalerz, L; Nizankowska, E; Pinis, G; Swanson, LJ; Szczeklik, A; Wright, S; Zetterström, O	1
Busse, WW; Horwitz, RJ; McGill, KA	1
Barberà, JA; Chung, KF; Gómez, FP; Iglesia, R; Roca, J; Rodriguez-Roisin, R	1
Drazen, J	1
Callens, E; Djebbar, R; Ruff, F; Santais, MC	1
Bouboulis, D; Frieri, M; Lark, G; Sansone, G; Schaefer, PA; Therattil, JM; Wang, SF; Zitt, M	1
Lane, SJ	1
Abraham, WM; Allegra, L; Scuri, M	1
Dubé, LM; DuBuske, LM; Grossman, J; Lancaster, JF; Swanson, LJ	1
Carpentier, PJ; Dubé, LM; Kemp, JP; Lancaster, JF; Lazarus, SC; Lee, T; Ochs, RF; Wenzel, S	1
Kuna, P; Kupczyk, M	1
Bleecker, ER; Dubé, LM; Hasday, JD; Hebel, JR; Lanni, C; Meltzer, SS; Moore, WC; Wisniewski, P	1
Dellaripa, PF; Drazen, J; Roth, ME; Wechsler, ME	1
Lang, DM	1
Daffern, PJ; Pauls, JD; Simon, RA; Stevenson, DD	1
Bisgaard, H	1
Drazen, JM; Dubé, L; Israel, E; Juniper, EF; Moy, ML; Weiss, ST	1
Krawiec, ME; Wenzel, SE	1
García-Marcos, L; Schuster, A	1
Spector, SL	1
Adachi, M; Minoguchi, K	1
Hayden, ML	1
Abraham, WM; Ahmed, A; Bell, RL; Bouska, J; Cortes, A; Hinz, W; Lanni, C; Sielczak, MW	1
O'Donnell, M; Payne, AN	1
Barnes, NC; Barnes, PJ; Hui, KP; Kesterson, J; Rubin, P; Taylor, GW; Taylor, IK	1
Bukantz, SC	1
Raub, W	1
Dermarkarian, R; Drazen, JM; Israel, E; Rosenberg, M; Rubin, P; Sperling, R; Taylor, G	1

Reviews

30 review(s) available for zileuton and Asthma

Article	Year
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors. Journal of medicinal chemistry, 1992, Jul-10, Volume: 35, Issue:14 Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases; Neutrophils; Quinolines	1992
[What helps for persistent symptoms of asthma during inhalative steroid therapy?]. Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:42 Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Adult; Albuterol; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Child; Cyclopropanes; Drug Therapy, Combination; Ethanolamines; Formoterol Fumarate; Humans; Hydroxyurea; Leukotriene Antagonists; Quality of Life; Quinolines; Randomized Controlled Trials as Topic; Respiratory Function Tests; Salmeterol Xinafoate; Sulfides; Treatment Failure	2011
New treatments for asthma: the role of leukotriene modifier agents. Journal of the National Medical Association, 1999, Volume: 91, Issue:8 Suppl Topics: Acetates; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Asthma, Exercise-Induced; Cyclopropanes; Drug Evaluation; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome	1999
[Anti-leukotrienes in allergic diseases in children]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2003, Volume: 14, Issue:84 Topics: Acetates; Asthma; Child; Cyclopropanes; Humans; Hydroxyurea; Leukotriene Antagonists; Leukotrienes; Membrane Proteins; Quinolines; Receptors, Leukotriene; Sulfides	2003
Recent advances in the management of asthma using leukotriene modifiers. American journal of respiratory medicine : drugs, devices, and other interventions, 2003, Volume: 2, Issue:2 Topics: Acetates; Administration, Inhalation; Adolescent; Adult; Asthma; Child; Child, Preschool; Chromones; Controlled Clinical Trials as Topic; Cyclopropanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydroxyurea; Leukotriene Antagonists; Male; Middle Aged; Peak Expiratory Flow Rate; Quinolines; Respiratory Function Tests; Severity of Illness Index; Sulfides; Treatment Outcome	2003
Leukotrienes antagonists in the management of bronchial asthma. Romanian journal of internal medicine = Revue roumaine de medecine interne, 2003, Volume: 41, Issue:1 Topics: Asthma; Humans; Hydroxyurea; Leukotriene Antagonists; Leukotrienes	2003
Treatment of asthma with antileukotrienes: first line or last resort therapy? European journal of pharmacology, 2006, Mar-08, Volume: 533, Issue:1-3 Topics: Acetates; Animals; Asthma; Clinical Trials as Topic; Cyclopropanes; Humans; Hydroxyurea; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Lipoxygenase Inhibitors; Membrane Proteins; Quinolines; Receptors, Leukotriene; Respiratory System; Rhinitis; Sulfides	2006
Cysteinyl-leukotrienes and their receptors in asthma and other inflammatory diseases: critical update and emerging trends. Medicinal research reviews, 2007, Volume: 27, Issue:4 Topics: Adult; Animals; Asthma; Cardiovascular Diseases; Child; Child, Preschool; Dermatitis, Atopic; Female; Humans; Hydroxyurea; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Membrane Proteins; Pharmacogenetics; Receptors, Leukotriene; Receptors, Purinergic; Recombinant Proteins; Rhinitis, Allergic, Seasonal; SRS-A; Tissue Distribution	2007
Leukotriene inhibitors in the treatment of allergy and asthma. American family physician, 2007, Jan-01, Volume: 75, Issue:1 Topics: Acetates; Anti-Asthmatic Agents; Asthma; Asthma, Exercise-Induced; Cyclopropanes; Dermatitis, Atopic; Humans; Hydroxyurea; Hypersensitivity; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sulfides; Sulfonamides; Tosyl Compounds	2007
Zileuton: clinical implications of 5-Lipoxygenase inhibition in severe airway disease. International journal of clinical practice, 2007, Volume: 61, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Asthma; Dermatitis, Atopic; Drug Administration Schedule; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Pulmonary Disease, Chronic Obstructive; Rhinitis	2007
[Allergy and leukotrienes]. Klinicheskaia meditsina, 1995, Volume: 73, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Asthma; Dermatitis, Atopic; Humans; Hydroxyurea; Hypersensitivity; Leukotrienes; Lipoxygenase Inhibitors; Receptors, Leukotriene	1995
Leukotriene antagonists and inhibitors: clinical applications. Advances in prostaglandin, thromboxane, and leukotriene research, 1995, Volume: 23 Topics: Animals; Asthma; Glomerulonephritis; Humans; Hydroxyurea; Indoles; Inflammatory Bowel Diseases; Leukotriene Antagonists; Leukotrienes; Membrane Proteins; Propionates; Psoriasis; Quinolines; Receptors, Leukotriene	1995
Zileuton. Lancet (London, England), 1996, Aug-24, Volume: 348, Issue:9026 Topics: Arthritis, Rheumatoid; Asthma; Humans; Hydroxyurea; Lipoxygenase Inhibitors	1996
Leukotrienes in asthma. The potential therapeutic role of antileukotriene agents. Archives of internal medicine, 1996, Oct-28, Volume: 156, Issue:19 Topics: Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Humans; Hydroxyurea; Indoles; Inflammation; Inflammation Mediators; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Sulfonamides; Tosyl Compounds	1996
[5-lipoxygenase inhibitors in asthma therapy]. Nihon rinsho. Japanese journal of clinical medicine, 1996, Volume: 54, Issue:11 Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acids; Asthma; Humans; Hydroxyurea; Lipoxygenase Inhibitors	1996
Antileukotriene therapy for asthma. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Dec-01, Volume: 53, Issue:23 Topics: Asthma; Humans; Hydroxyurea; Inflammation; Leukotrienes; Lipoxygenase Inhibitors	1996
Antileukotriene agents. Current opinion in pulmonary medicine, 1997, Volume: 3, Issue:3 Topics: Anti-Asthmatic Agents; Asthma; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Sulfonamides; Tosyl Compounds	1997
New directions in asthma drug therapy. Hospital practice (1995), 1998, Feb-15, Volume: 33, Issue:2 Topics: Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Chromones; Humans; Hydroxyurea; Indoles; Inflammation; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Sulfonamides; Tosyl Compounds	1998
The role of antileukotrienes in asthma management. Current opinion in pulmonary medicine, 1998, Volume: 4, Issue:1 Topics: Acetates; Animals; Anti-Asthmatic Agents; Asthma; Chromones; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds	1998
New approaches to anti-inflammatory therapy for asthma. The American journal of medicine, 1998, Volume: 104, Issue:3 Topics: Anti-Asthmatic Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Dicarboxylic Acids; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Steroids; Sulfonamides; Tosyl Compounds	1998
The role of leukotriene modifiers in the treatment of asthma. American journal of respiratory and critical care medicine, 1998, Volume: 157, Issue:5 Pt 1 Topics: Animals; Asthma; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Sulfonamides; Tosyl Compounds	1998
Clinical pharmacology of leukotriene receptor antagonists and 5-lipoxygenase inhibitors. American journal of respiratory and critical care medicine, 1998, Volume: 157, Issue:6 Pt 2 Topics: Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Phenylcarbamates; Randomized Controlled Trials as Topic; Sulfonamides; Tosyl Compounds; Treatment Outcome	1998
[Potential importance of antileukotrienes in the treatment of asthma and other inflammatory diseases: apropos of a new pharmacological class]. La Revue de medecine interne, 1998, Volume: 19, Issue:2 Topics: Acetophenones; Adult; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Asthma; Bronchoconstriction; Child; Clinical Trials as Topic; Crohn Disease; Cystic Fibrosis; Haplorhini; Humans; Hydroxyurea; Indazoles; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Phenylcarbamates; Psoriasis; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome; Sulfonamides; Tetrazoles; Tosyl Compounds	1998
Leukotriene antagonism in asthma and rhinitis. Respiratory medicine, 1998, Volume: 92, Issue:6 Topics: Acetates; Asthma; Bronchi; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotriene D4; Lipoxygenase Inhibitors; Membrane Proteins; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Rhinitis; Sinusitis; Sulfides; Sulfonamides; Tosyl Compounds	1998
[The role of leukotrienes in inflammation and leukotriene inhibitors]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 1999, Volume: 7, Issue:39 Topics: Acetates; Arachidonate 5-Lipoxygenase; Asthma; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds	1999
Leukotriene modifiers in pediatric asthma management. Pediatrics, 2001, Volume: 107, Issue:2 Topics: Acetates; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Asthma; Child; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Membrane Proteins; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds	2001
Leukotriene inhibitors and non-steroidal therapies in the treatment of asthma. Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:1 Topics: Acetates; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Asthma; Bronchoconstriction; Child; Clinical Trials as Topic; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Phenylcarbamates; Phosphodiesterase Inhibitors; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome	2001
Antileukotrienes in asthma: present situation. Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:3 Topics: Acetates; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Chromones; Clinical Trials as Topic; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds	2001
[Leukotriene modifiers]. Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59, Issue:10 Topics: Acetates; Asthma; Chromones; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Phenylcarbamates; Practice Guidelines as Topic; Quinolines; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds	2001
Leukotriene modifiers. Expanded role may be on horizon. Advance for nurse practitioners, 2000, Volume: 8, Issue:10 Topics: Acetates; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Cyclopropanes; Drug Interactions; Drug Therapy, Combination; Forced Expiratory Volume; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Patient Compliance; Phenylcarbamates; Quinolines; Safety; Steroids; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome	2000

Trials

25 trial(s) available for zileuton and Asthma

Article	Year
Genome-wide association study of leukotriene modifier response in asthma. The pharmacogenomics journal, 2016, Volume: 16, Issue:2 Topics: Acetates; Anti-Asthmatic Agents; Asthma; Cohort Studies; Cyclopropanes; Gene-Environment Interaction; Genetic Loci; Genome-Wide Association Study; Genotype; Humans; Hydroxyurea; Leukotrienes; Phenotype; Polymorphism, Single Nucleotide; Quinolines; Sulfides	2016
5-lipoxygenase pharmacogenetics in asthma: overlap with Cys-leukotriene receptor antagonist loci. Pharmacogenetics and genomics, 2009, Volume: 19, Issue:3 Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Cysteine; Female; Forced Expiratory Volume; Genotype; Humans; Hydroxyurea; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Middle Aged; Polymorphism, Single Nucleotide; Quinolines; Receptors, Leukotriene; Sulfides	2009
Role of add-on zileuton on total exhaled, large airway, and small airway/alveolar nitric oxide in moderate-severe persistent adult asthmatics on fluticasone 250 microg/Salmeterol 50 microg. Pulmonary pharmacology & therapeutics, 2009, Volume: 22, Issue:6 Topics: Adult; Albuterol; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Drug Therapy, Combination; Eosinophils; Female; Fluticasone; Humans; Hydroxyurea; Juniperus; Leukocyte Count; Male; Middle Aged; Nitric Oxide; Prospective Studies; Pulmonary Alveoli; Respiratory Function Tests; Respiratory System; Salmeterol Xinafoate; Spirometry	2009
Suppression of leukotriene B4 generation by ex-vivo neutrophils isolated from asthma patients on dietary supplementation with gammalinolenic acid-containing borage oil: possible implication in asthma. Clinical & developmental immunology, 2004, Volume: 11, Issue:1 Topics: Adult; Aged; Arthritis, Rheumatoid; Asthma; Dietary Supplements; Double-Blind Method; Fatty Acids; Female; gamma-Linolenic Acid; Humans; Hydroxyurea; Leukotriene B4; Lipoxygenase Inhibitors; Male; Middle Aged; Neutrophils; Plant Oils; Prospective Studies	2004
Effect of leukotriene modifier drugs on the safety of oral aspirin challenges. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 97, Issue:5 Topics: Acetates; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Asthmatic Agents; Aspirin; Asthma; Cyclopropanes; Desensitization, Immunologic; Drug Hypersensitivity; Female; Forced Expiratory Volume; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Middle Aged; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds; Treatment Outcome	2006
Zileuton added to low-dose inhaled beclomethasone for the treatment of moderate to severe persistent asthma. Respiratory medicine, 2007, Volume: 101, Issue:6 Topics: Adolescent; Adult; Aged; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Beclomethasone; Double-Blind Method; Drug Therapy, Combination; Forced Expiratory Volume; Glucocorticoids; Humans; Hydroxyurea; Middle Aged; Peak Expiratory Flow Rate; Severity of Illness Index; Single-Blind Method	2007
The safety and efficacy of zileuton controlled-release tablets as adjunctive therapy to usual care in the treatment of moderate persistent asthma: a 6-month randomized controlled study. The Journal of asthma : official journal of the Association for the Care of Asthma, 2007, Volume: 44, Issue:4 Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Asthma; Child; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Female; Forced Expiratory Volume; Glucocorticoids; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Male; Middle Aged; Peak Expiratory Flow Rate; Quality of Life; Tablets	2007
Efficacy of zileuton controlled-release tablets administered twice daily in the treatment of moderate persistent asthma: a 3-month randomized controlled study. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2007, Volume: 99, Issue:2 Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Child; Chronic Disease; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Forced Expiratory Volume; Humans; Hydroxyurea; Inhalation; Middle Aged; Tablets; Treatment Outcome	2007
Clinical pattern of zileuton-associated liver injury: results of a 12-month study in patients with chronic asthma. Drug safety, 2007, Volume: 30, Issue:9 Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Asthma; Chemical and Drug Induced Liver Injury; Chronic Disease; Female; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Liver Function Tests; Male; Prospective Studies	2007
Effect of chronic 5-lipoxygenase inhibition on airway hyperresponsiveness in asthmatic subjects. American journal of respiratory and critical care medicine, 1995, Volume: 152, Issue:4 Pt 1 Topics: Adult; Arachidonate 5-Lipoxygenase; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cold Temperature; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Male; Single-Blind Method; Time Factors	1995
Effect of 5-lipoxygenase inhibition on bronchoconstriction and airway inflammation in nocturnal asthma. American journal of respiratory and critical care medicine, 1995, Volume: 152, Issue:3 Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cross-Over Studies; Double-Blind Method; Forced Expiratory Volume; Humans; Hydroxyurea; Inflammation; Leukotriene E4; Leukotrienes; Lipoxygenase Inhibitors; Middle Aged	1995
Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthma. The Journal of allergy and clinical immunology, 1994, Volume: 94, Issue:6 Pt 1 Topics: Adult; Aspirin; Asthma; Blood Proteins; Chymases; Cross-Over Studies; Double-Blind Method; Eosinophil Granule Proteins; Female; Histamine; Humans; Hydroxyurea; Leukotrienes; Male; Mast Cells; Middle Aged; Nasal Mucosa; Ribonucleases; Serine Endopeptidases; Tryptases	1994
The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma. Annals of internal medicine, 1993, Dec-01, Volume: 119, Issue:11 Topics: Adult; Albuterol; Asthma; Double-Blind Method; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Hydroxyurea; Leukotriene E4; Lipoxygenase Inhibitors; Male; Single-Blind Method	1993
The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin. The American review of respiratory disease, 1993, Volume: 148, Issue:6 Pt 1 Topics: Adult; Arachidonate 5-Lipoxygenase; Aspirin; Asthma; Bronchoconstriction; Double-Blind Method; Drug Hypersensitivity; Female; Forced Expiratory Volume; Humans; Hydroxyurea; Leukotriene E4; Lipoxygenase Inhibitors; Male; Middle Aged	1993
Effect of treatment with zileuton, a 5-lipoxygenase inhibitor, in patients with asthma. A randomized controlled trial. Zileuton Clinical Trial Group. JAMA, 1996, Mar-27, Volume: 275, Issue:12 Topics: Adrenergic beta-Agonists; Adult; Analysis of Variance; Asthma; Double-Blind Method; Drug Administration Schedule; Drug Monitoring; Female; Forced Expiratory Volume; Glucocorticoids; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Liver; Liver Function Tests; Male; Peak Expiratory Flow Rate; Quality of Life	1996
Acute and chronic effects of a 5-lipoxygenase inhibitor in asthma: a 6-month randomized multicenter trial. Zileuton Study Group. The Journal of allergy and clinical immunology, 1996, Volume: 98, Issue:5 Pt 1 Topics: Adolescent; Adrenergic beta-Agonists; Adult; Anti-Asthmatic Agents; Asthma; Bronchoconstriction; Double-Blind Method; Drug Therapy, Combination; Eosinophils; Female; Forced Expiratory Volume; Histamine Antagonists; Humans; Hydroxyurea; Leukocyte Count; Leukotrienes; Lipoxygenase Inhibitors; Liver Function Tests; Male; Middle Aged; Time Factors; Treatment Outcome	1996
A randomized controlled trial comparing zileuton with theophylline in moderate asthma. The Zileuton Study Group. Archives of internal medicine, 1998, Jan-26, Volume: 158, Issue:2 Topics: Adult; Asthma; Bronchodilator Agents; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Lung Volume Measurements; Male; Middle Aged; Severity of Illness Index; Theophylline; Time Factors; Treatment Outcome	1998
Effects of single-dose zileuton on bronchial hyperresponsiveness in asthmatic patients treated with inhaled corticosteroids. The European respiratory journal, 1997, Volume: 10, Issue:12 Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Histamine; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Male; Middle Aged; Reference Values; Respiratory Function Tests; Sensitivity and Specificity; Water	1997
Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics. American journal of respiratory and critical care medicine, 1998, Volume: 157, Issue:4 Pt 1 Topics: Adrenergic beta-Agonists; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Forced Expiratory Volume; Glucocorticoids; Histamine; Humans; Hydroxyurea; Leukotriene Antagonists; Leukotriene D4; Lipoxygenase Inhibitors; Male; Middle Aged; Peak Expiratory Flow Rate	1998
The effects of 5-lipoxygenase inhibition by zileuton on platelet-activating-factor-induced pulmonary abnormalities in mild asthma. American journal of respiratory and critical care medicine, 1998, Volume: 157, Issue:5 Pt 1 Topics: Adult; Airway Resistance; Asthma; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydroxyurea; Leukotrienes; Lipoxygenase Inhibitors; Male; Neutropenia; Oxygen; Platelet Activating Factor; Pulmonary Gas Exchange; Respiratory Mechanics; Ventilation-Perfusion Ratio	1998
Randomized trial of zileuton in patients with moderate asthma: effect of reduced dosing frequency and amounts on pulmonary function and asthma symptoms. Zileuton Study Group. The American journal of managed care, 1997, Volume: 3, Issue:4 Topics: Adolescent; Adult; Aged; Asthma; Double-Blind Method; Drug Administration Schedule; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Managed Care Programs; Middle Aged; Respiratory Function Tests; Respiratory System Agents; United States	1997
Safety and clinical efficacy of zileuton in patients with chronic asthma. The American journal of managed care, 1998, Volume: 4, Issue:6 Topics: Asthma; Chronic Disease; Disease Management; Forced Expiratory Volume; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Managed Care Programs; Safety; Treatment Outcome; United States	1998
Anti-inflammatory effects of zileuton in a subpopulation of allergic asthmatics. American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:4 Pt 1 Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cytokines; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hydroxyurea; Inflammation Mediators; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Male; Skin Tests	2000
Effect of a 5-lipoxygenase inhibitor on leukotriene generation and airway responses after allergen challenge in asthmatic patients. Thorax, 1991, Volume: 46, Issue:3 Topics: Adult; Allergens; Asthma; Double-Blind Method; Forced Expiratory Volume; Humans; Hydroxyurea; Leukotriene B4; Leukotriene E4; Lipoxygenase Inhibitors; Male; SRS-A; Time Factors	1991
The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air. The New England journal of medicine, 1990, Dec-20, Volume: 323, Issue:25 Topics: Asthma; Bronchial Provocation Tests; Bronchoconstriction; Calcimycin; Cold Temperature; Double-Blind Method; Eicosanoids; Humans; Humidity; Hydroxyurea; Lipoxygenase Inhibitors; Male	1990

Other Studies

25 other study(ies) available for zileuton and Asthma

Article	Year
Synthesis, structure-activity relationships, and pharmacological evaluation of pyrrolo[3,2,1-ij]quinoline derivatives: potent histamine and platelet activating factor antagonism and 5-lipoxygenase inhibitory properties. Potential therapeutic application i Journal of medicinal chemistry, 1995, Feb-17, Volume: 38, Issue:4 Topics: Animals; Asthma; Female; Guinea Pigs; Histamine Antagonists; In Vitro Techniques; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Quinolines; Rabbits; Rats; Rats, Sprague-Dawley; Respiratory Function Tests; Skin Tests; Structure-Activity Relationship	1995
Discovery of the Oral Leukotriene C4 Synthase Inhibitor (1 Journal of medicinal chemistry, 2019, 09-12, Volume: 62, Issue:17 Topics: Administration, Oral; Animals; Anti-Asthmatic Agents; Asthma; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Glutathione Transferase; Humans; Molecular Structure; Pyrazines; Rats; Structure-Activity Relationship	2019
Zileuton use and phenotypic features in asthma. Pulmonary pharmacology & therapeutics, 2020, Volume: 60 Topics: Adult; Aged; Anti-Asthmatic Agents; Asthma; Female; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Lung; Male; Middle Aged; Phenotype; Respiratory Function Tests; Retrospective Studies; Severity of Illness Index	2020
The phosphatidylinositide 3-kinase (PI3K) signaling pathway is a determinant of zileuton response in adults with asthma. The pharmacogenomics journal, 2018, Volume: 18, Issue:5 Topics: Asthma; Cell Line; Humans; Hydroxyurea; Leukotrienes; Phosphatidylinositol 3-Kinases; Polymorphism, Single Nucleotide; Quantitative Trait Loci; RNA, Messenger; Signal Transduction	2018
Airway remodeling in asthma: tumor of the airway? Respiration; international review of thoracic diseases, 2013, Volume: 86, Issue:5 Topics: Airway Remodeling; Allergens; Animals; Asthma; Hydroxyurea; Leukotriene Antagonists; Lung; Male	2013
Effects of zileuton on airway smooth muscle remodeling after repeated allergen challenge in brown Norway rats. Respiration; international review of thoracic diseases, 2013, Volume: 86, Issue:5 Topics: Airway Remodeling; Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Drug Evaluation, Preclinical; Hydroxyurea; Leukotriene Antagonists; Lung; Male; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Rats; Respiratory Function Tests; T-Lymphocytes	2013
Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13. The Journal of clinical investigation, 2016, Volume: 126, Issue:2 Topics: Anemia, Sickle Cell; Animals; Asthma; Disease Models, Animal; Hydroxyurea; Interleukin-13; Leukotrienes; Mice; Mice, Knockout; Placenta Growth Factor; Pregnancy Proteins; Th2 Cells	2016
Zileuton, a 5-lipoxygenase inhibitor, increases production of thromboxane A2 and platelet aggregation in patients with asthma. American journal of hematology, 2003, Volume: 74, Issue:1 Topics: Adult; Aged; Asthma; Female; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Male; Middle Aged; Platelet Aggregation; Thromboxane A2; Thromboxane B2	2003
Leukotriene modifier use and asthma severity: how is a new medication being used by adults with asthma? Archives of internal medicine, 2004, Mar-22, Volume: 164, Issue:6 Topics: Acetates; Adult; Anti-Asthmatic Agents; Asthma; Cyclopropanes; Female; Health Status Indicators; Hospitalization; Humans; Hydroxyurea; Leukotriene Antagonists; Logistic Models; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Quinolines; Sulfides	2004
WY-50,295 tromethamine, a novel, orally active 5-lipoxygenase inhibitor: biochemical characterization and antiallergic activity. European journal of pharmacology, 1993, May-19, Volume: 236, Issue:2 Topics: Administration, Oral; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Asthma; Female; Guinea Pigs; Humans; Hydroxyurea; Indoles; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages; Male; Mice; Naphthaleneacetic Acids; Prostaglandin-Endoperoxide Synthases; Quinolines; Rabbits; Rats; Rats, Wistar	1993
Zileuton for asthma. The Medical letter on drugs and therapeutics, 1997, Feb-28, Volume: 39, Issue:995 Topics: Adolescent; Adult; Asthma; Child; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Humans; Hydroxyurea; Intestinal Absorption; Leukotrienes; Lipoxygenase Inhibitors; Propranolol; Theophylline; Warfarin	1997
Allergen-stimulated leukotriene B4 and interleukin-8 levels in patients with asthma and allergic rhinitis-modulation by a lipid pathway inhibitor. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1998, Volume: 81, Issue:4 Topics: Adult; Aged; Allergens; Asthma; Female; Humans; Hydroxyurea; Interleukin-8; Leukocytes, Mononuclear; Leukotriene B4; Lipoxygenase Inhibitors; Male; Middle Aged; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal	1998
Drugs for asthma. The Medical letter on drugs and therapeutics, 1999, Jan-15, Volume: 41, Issue:1044 Topics: Acetates; Administration, Inhalation; Administration, Oral; Adolescent; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Asthma; Bone Density; Bronchial Spasm; Bronchodilator Agents; Child; Child, Preschool; Choice Behavior; Cromolyn Sodium; Cyclopropanes; Exercise; Female; Growth; Humans; Hydroxyurea; Indoles; Infant, Newborn; Ipratropium; Lactation; Leukotriene Antagonists; Phenylcarbamates; Pregnancy; Pregnancy Complications; Quinolines; Salmeterol Xinafoate; Sulfides; Sulfonamides; Tachycardia; Theophylline; Tosyl Compounds	1999
The effects of multiple dosing with zileuton on antigen-induced responses in sheep. Pulmonary pharmacology & therapeutics, 1998, Volume: 11, Issue:4 Topics: Airway Resistance; Animals; Asthma; Bronchial Provocation Tests; Disease Models, Animal; Drug Administration Schedule; Female; Hydroxyurea; Leukotriene Antagonists; Random Allocation; Sheep	1998
Drugs for asthma. The Medical letter on drugs and therapeutics, 2000, Mar-06, Volume: 42, Issue:1073 Topics: Acetates; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Bronchial Spasm; Child; Cromolyn Sodium; Cyclopropanes; Exercise; Female; Growth Disorders; Humans; Hydroxyurea; Indoles; Ipratropium; Lactation; Leukotriene Antagonists; Nebulizers and Vaporizers; Nedocromil; Phenylcarbamates; Pregnancy; Pregnancy Complications; Quinolines; Salmeterol Xinafoate; Sulfides; Sulfonamides; Theophylline; Tosyl Compounds	2000
The use of newer asthma and allergy medications during pregnancy. The American College of Obstetricians and Gynecologists (ACOG) and The American College of Allergy, Asthma and Immunology (ACAAI). Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2000, Volume: 84, Issue:5 Topics: Abnormalities, Drug-Induced; Acetates; Administration, Inhalation; Administration, Intranasal; Administration, Oral; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Albuterol; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Budesonide; Chlorpheniramine; Cyclopropanes; Ephedrine; Female; Histamine H1 Antagonists; Humans; Hydroxyurea; Hypersensitivity; Indoles; Ipratropium; Leukotriene Antagonists; Metaproterenol; Nasal Decongestants; Nebulizers and Vaporizers; Nedocromil; Phenylcarbamates; Pregnancy; Pregnancy Complications; Quinolines; Salmeterol Xinafoate; Sulfides; Sulfonamides; Terbutaline; Tosyl Compounds; Tripelennamine	2000
Recurrent panniculitis in a man with asthma receiving treatment with leukotriene-modifying agents. Mayo Clinic proceedings, 2000, Volume: 75, Issue:6 Topics: Acetates; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Cyclopropanes; Diagnosis, Differential; Erythema Induratum; Humans; Hydroxyurea; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Middle Aged; Panniculitis, Nodular Nonsuppurative; Quinolines; Sulfides	2000
Antileukotriene agents and aspirin-sensitive asthma: are we removing the second bassoonist or skating to where the puck is gonna be? Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2000, Volume: 85, Issue:1 Topics: Aspirin; Asthma; Bronchial Spasm; Humans; Hydroxyurea; Leukotriene Antagonists; Therapeutic Equivalency	2000
Lack of effect of the 5-lipoxygenase inhibitor zileuton in blocking oral aspirin challenges in aspirin-sensitive asthmatics. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2000, Volume: 85, Issue:1 Topics: Administration, Oral; Aspirin; Asthma; Desensitization, Immunologic; Humans; Hydroxyurea; Leukotrienes; Lipoxygenase Inhibitors	2000
Clinical predictors of health-related quality of life depend on asthma severity. American journal of respiratory and critical care medicine, 2001, Volume: 163, Issue:4 Topics: Adult; Albuterol; Analysis of Variance; Asthma; Female; Follow-Up Studies; Humans; Hydroxyurea; Male; Predictive Value of Tests; Probability; Quality of Life; Respiratory Function Tests; Retrospective Studies; Severity of Illness Index; Sickness Impact Profile; Treatment Outcome	2001
Safety of antileukotriene agents in asthma management. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2001, Volume: 86, Issue:6 Suppl 1 Topics: Acetates; Asthma; Churg-Strauss Syndrome; Clinical Trials as Topic; Cyclopropanes; Humans; Hydroxyurea; Indoles; Leukotriene Antagonists; Phenylcarbamates; Quinolines; Sulfides; Sulfonamides; Tosyl Compounds	2001
The 5-lipoxygenase inhibitor zileuton blocks antigen-induced late airway responses, inflammation and airway hyperresponsiveness in allergic sheep. European journal of pharmacology, 1992, Jul-07, Volume: 217, Issue:2-3 Topics: Administration, Oral; Animals; Antigens; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Calcimycin; Dose-Response Relationship, Drug; Hydroxyurea; Leukotriene B4; Lipoxygenase Inhibitors; Sheep	1992
Therapeutic approaches to reduce airway inflammation. Agents and actions. Supplements, 1991, Volume: 35 Topics: Animals; Anti-Inflammatory Agents; Asthma; Blood Platelets; Bronchi; Cell Adhesion Molecules; Humans; Hydroxyurea; Intercellular Adhesion Molecule-1; Interleukin-5; Lipoxygenase Inhibitors	1991
Asthma: the molecular light at the end of the tracheal tunnel. Hospital practice (Office ed.), 1991, Feb-15, Volume: 26, Issue:2 Topics: Asthma; Humans; Hydroxyeicosatetraenoic Acids; Hydroxyurea; Leukotrienes; Lipoxygenase Inhibitors; Propionates; Quinolines	1991
From the National Institutes of Health. JAMA, 1991, Mar-06, Volume: 265, Issue:9 Topics: Arthritis, Juvenile; Asthma; CD4 Antigens; Cells, Cultured; Exotoxins; HIV-1; HLA Antigens; Humans; Hydroxyurea; Immunotoxins; Lipoxygenase Inhibitors; National Institutes of Health (U.S.); Recombinant Proteins; Respiratory Hypersensitivity; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; T-Lymphocytes; United States	1991

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