zilascorb and Fibrosarcoma

zilascorb has been researched along with Fibrosarcoma* in 1 studies

Other Studies

1 other study(ies) available for zilascorb and Fibrosarcoma

Article	Year
Benzylideneascorbate induces apoptosis in L929 tumor cells. Biochemical and biophysical research communications, 1993, Jul-15, Volume: 194, Issue:1 Sodium 5,6-benzylideneascorbate (SBA), which is known to be an antitumor substance, was found to induce apoptotic cell death of L929 tumor cells directly in a concentration- and time-dependent manner. The dying cells exhibited cell shrinkage, disappearance of cell surface microvilli, chromatin condensation and DNA fragmentation into nucleosomal oligomers characteristic of apoptosis. These results indicate a possible mechanism by which SBA induces tumor regression in vivo. Topics: Animals; Antineoplastic Agents; Apoptosis; Ascorbic Acid; Benzylidene Compounds; DNA Damage; DNA, Neoplasm; Electrophoresis, Agar Gel; Fibrosarcoma; Kinetics; Mice; Microscopy, Electron; Molecular Structure; Tumor Cells, Cultured	1993

Article

Year

Benzylideneascorbate induces apoptosis in L929 tumor cells.

Biochemical and biophysical research communications, 1993, Jul-15, Volume: 194, Issue:1

Sodium 5,6-benzylideneascorbate (SBA), which is known to be an antitumor substance, was found to induce apoptotic cell death of L929 tumor cells directly in a concentration- and time-dependent manner. The dying cells exhibited cell shrinkage, disappearance of cell surface microvilli, chromatin condensation and DNA fragmentation into nucleosomal oligomers characteristic of apoptosis. These results indicate a possible mechanism by which SBA induces tumor regression in vivo.

Topics: Animals; Antineoplastic Agents; Apoptosis; Ascorbic Acid; Benzylidene Compounds; DNA Damage; DNA, Neoplasm; Electrophoresis, Agar Gel; Fibrosarcoma; Kinetics; Mice; Microscopy, Electron; Molecular Structure; Tumor Cells, Cultured

1993