zidovudine triphosphate has been researched along with HIV Coinfection in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (32.14) | 18.2507 |
| 2000's | 13 (46.43) | 29.6817 |
| 2010's | 6 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amblard, F; Bassit, L; Bondada, L; Coats, SJ; Detorio, M; Grier, J; Hernandez-Santiago, BI; Koontz, D; Mellors, JW; Rapp, KL; Schinazi, RF; Sluis-Cremer, N | 1 |
| Barreto-de-Souza, V; Frolova, S; Karpenko, I; Khandazhinskaya, A; Kochetkov, S; Margolis, L; Vanpouille, C; Zicari, S | 1 |
| Bridges, AS; Cohen, MS; Dumond, JB; Fiscus, SA; Forrest, A; Kashuba, AD; Kendrick, R; Reddy, YS; Troiani, L; Yang, KH | 1 |
| Bodem, J; Buchholz, B; Corona, A; Di Santo, R; Jordan, M; Maccioni, E; Schneider, A; Spöring, I; Tramontano, E; Wöhrl, BM | 1 |
| Gatanaga, H; Ha, do Q; Hosokawa, S; Kato, S; Kikuchi, Y; Kinai, E; Kinh, NV; Lam, NV; Liem, NT; Oka, S; Sadatsuki, M | 1 |
| Hsu, CH; Taylor, JM | 1 |
| Marquet, R; Metzner, P; Schütte, C; von Kleist, M | 1 |
| Anderson, PL; Bushman, LR; Gardner, EM; Klein, B; Lichtenstein, K; Mawhinney, S; Meditz, A; Predhomme, J; Rower, JE; Zheng, JH | 1 |
| Heneine, W; Merigan, T; Qari, SH; Vandamme, AM; Winters, M | 1 |
| Hurwitz, SJ; Schinazi, RF | 1 |
| Gronowitz, JS; Källander, CF; Lennerstrand, J; Malmsten, A; Shao, XW; Sönnerborg, A; Unge, T | 1 |
| Anderson, PL; Bushman, L; Delahunty, T; Fletcher, CV; King, T; Ray, M | 1 |
| Acosta, EP; Bassett, R; Eron, JJ; Fischl, MA; Johnson, VA; Kuritzkes, DR; Long, MC; Moore, JD; Sommadossi, JP | 1 |
| Bénech, H; Dehée, A; Dollfus, C; Durand-Gasselin, L; Garbarg-Chenon, A; Grassi, J; Leverger, G; Pruvost, A; Tabone, MD; Vaudre, G | 1 |
| Mitsuya, H; Shirasaka, T; Ueno, T | 1 |
| Back, D; Barry, M; Beeching, N; Breckenridge, A; Carey, P; Fox, R; Nye, F; Timmins, D; Veal, G; Wild, M | 1 |
| Hall, ET; Kuchta, RD; Melançon, P; Yan, JP | 1 |
| Avramis, VI; Gomperts, E; Kwock, R; Solorzano, MM | 1 |
| Bardeguez, AD; Blanchard, S; Flynn, PM; Fridland, A; Jimenez, E; Robbins, B; Rodman, JH; Rodriguez, JF | 1 |
| Font, E; García, H; Rodriguez, JF; Rosario, O; Santana, J; Sommadossi, JP | 1 |
| García, H; Rodriguez, JF; Rodriguez, JL; Rosario, O; Santana, J | 1 |
| Anderson, PL; Brundage, RC; Bushman, LR; Fletcher, CV; Kakuda, TN; Kawle, SP; Remmel, RP; Weller, D | 1 |
| Darque, A; Moore, JD; Sommadossi, JP; Valette, G; Zhou, XJ | 1 |
| Back, DJ; Barry, MG; Dann, L; Gibbons, SE; Hoggard, PG; Khoo, SH; Lloyd, J; Loveday, C; Wilkins, EG | 1 |
| Baker, RC; Brady, MT; Hunkler, JA; McOwen, NM; Nahata, MC; Sobol, BJ; Wintermeyer, SM | 1 |
| Duan, C; Kuritzkes, DR; McHenry, CS; Petropoulos, CJ; Poticha, D; Stoeckli, TC; Whitcomb, JM | 1 |
| Hamzeh, FM; Kornhauser, DM; Kuwahara, SK; Lewis, LD; Lietman, PS; Slusher, JT | 1 |
| Britton, S; Eriksson, S; Jacobsson, B; Törnevik, Y | 1 |
3 trial(s) available for zidovudine triphosphate and HIV Coinfection
| Article | Year |
|---|---|
Zidovudine phosphorylation in HIV-infected patients and seronegative volunteers.
Topics: Acquired Immunodeficiency Syndrome; Adult; Biotransformation; Dideoxynucleotides; HIV Infections; HIV Seronegativity; Humans; Leukocytes, Mononuclear; Middle Aged; Phosphorylation; Reference Values; Thymine Nucleotides; Zidovudine | 1994 |
Determination of zidovudine triphosphate intracellular concentrations in peripheral blood mononuclear cells from human immunodeficiency virus-infected individuals by tandem mass spectrometry.
Topics: Adult; Aged; Anti-HIV Agents; Calibration; Cells, Cultured; Chromatography, High Pressure Liquid; Dideoxynucleotides; Female; HIV Infections; Humans; Male; Mass Spectrometry; Middle Aged; Monocytes; Nucleotides; Reference Standards; Thymine Nucleotides; Zidovudine | 1999 |
Zidovudine triphosphate and lamivudine triphosphate concentration-response relationships in HIV-infected persons.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Middle Aged; Prospective Studies; Regression Analysis; Reverse Transcriptase Inhibitors; RNA, Viral; Thymine Nucleotides; Zidovudine | 2000 |
25 other study(ies) available for zidovudine triphosphate and HIV Coinfection
| Article | Year |
|---|---|
Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.
Topics: Anti-HIV Agents; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Molecular Structure; Reverse Transcriptase Inhibitors | 2009 |
A new antiviral: chimeric 3TC-AZT phosphonate efficiently inhibits HIV-1 in human tissues ex vivo.
Topics: Anti-HIV Agents; Dideoxynucleotides; Drug Evaluation, Preclinical; HIV Infections; HIV-1; Humans; In Vitro Techniques; Lamivudine; Palatine Tonsil; Thymine Nucleotides; Virus Replication; Zidovudine | 2014 |
Pharmacokinetic Modeling of Lamivudine and Zidovudine Triphosphates Predicts Differential Pharmacokinetics in Seminal Mononuclear Cells and Peripheral Blood Mononuclear Cells.
Topics: Adult; Anti-HIV Agents; Biological Availability; Biological Transport; Blood Cells; Computer Simulation; Cytidine Triphosphate; Dideoxynucleotides; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Models, Statistical; Semen; Thymine Nucleotides; Time Factors; Zidovudine | 2015 |
Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors.
Topics: Amino Acid Sequence; Amino Acid Substitution; Anti-HIV Agents; Cloning, Molecular; Dideoxynucleotides; Drug Resistance, Multiple, Viral; Enzyme Inhibitors; Escherichia coli; Gene Expression; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Recombinant Proteins; Ribonuclease H, Human Immunodeficiency Virus; Thymine Nucleotides; Zidovudine | 2016 |
High Plasma Concentrations of Zidovudine (AZT) Do Not Parallel Intracellular Concentrations of AZT-Triphosphates in Infants During Prevention of Mother-to-Child HIV-1 Transmission.
Topics: Adult; Anti-HIV Agents; Chromatography, High Pressure Liquid; Dideoxynucleotides; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Longitudinal Studies; Male; Mothers; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Thymine Nucleotides; Treatment Outcome; Young Adult; Zidovudine | 2016 |
Nonparametric comparison of two survival functions with dependent censoring via nonparametric multiple imputation.
Topics: Anti-HIV Agents; Clinical Trials as Topic; Data Interpretation, Statistical; Dideoxynucleotides; HIV Infections; Humans; Placebos; Statistics, Nonparametric; Survival Analysis; Thymine Nucleotides; Zidovudine | 2009 |
HIV-1 polymerase inhibition by nucleoside analogs: cellular- and kinetic parameters of efficacy, susceptibility and resistance selection.
Topics: Anti-HIV Agents; Base Sequence; Dideoxynucleotides; DNA, Viral; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Nucleosides; pol Gene Products, Human Immunodeficiency Virus; Reverse Transcriptase Inhibitors; RNA, Viral; Thymine Nucleotides; Zidovudine | 2012 |
Effect of HIV-1 infection and sex on the cellular pharmacology of the antiretroviral drugs zidovudine and lamivudine.
Topics: Adult; Anti-HIV Agents; Black or African American; Cytidine Triphosphate; Dideoxynucleotides; Female; HIV Infections; Humans; Lamivudine; Longitudinal Studies; Male; Prospective Studies; Sex Factors; Thymine Nucleotides; Zidovudine | 2012 |
A rapid phenotypic assay for detecting multiple nucleoside analogue reverse transcriptase inhibitor-resistant HIV-1 in plasma.
Topics: Adenosine Monophosphate; Dideoxynucleotides; Drug Evaluation, Preclinical; Drug Resistance, Multiple, Viral; HIV Infections; HIV-1; Humans; Mutation; Phenotype; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA-Directed DNA Polymerase; Thymine Nucleotides; Zidovudine | 2002 |
Development of a pharmacodynamic model for HIV treatment with nucleoside reverse transcriptase and protease inhibitors.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Cytidine Triphosphate; Dideoxynucleotides; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Models, Statistical; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Viral Load; Zidovudine | 2002 |
Use of HIV-1 reverse transcriptase recovered from human plasma for phenotypic drug susceptibility testing.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleotides; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Reproducibility of Results; Stavudine; Thymine Nucleotides; Virion; Zidovudine | 2003 |
Quantitation of zidovudine triphosphate concentrations from human peripheral blood mononuclear cells by anion exchange solid phase extraction and liquid chromatography-tandem mass spectroscopy; an indirect quantitation methodology.
Topics: Chemical Fractionation; Chromatography, Liquid; Dideoxynucleotides; Drug Stability; Enzyme-Linked Immunosorbent Assay; HIV Infections; Humans; Ion Exchange; Leukocytes, Mononuclear; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Thymine Nucleotides; Zidovudine | 2006 |
Intracellular nucleoside triphosphate concentrations in HIV-infected patients on dual nucleoside reverse transcriptase inhibitor therapy.
Topics: Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleotides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Reverse Transcriptase Inhibitors; Stavudine; Thymine Nucleotides; Zidovudine | 2007 |
High levels of zidovudine (AZT) and its intracellular phosphate metabolites in AZT- and AZT-lamivudine-treated newborns of human immunodeficiency virus-infected mothers.
Topics: Anti-HIV Agents; Dideoxynucleotides; Female; Follow-Up Studies; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Leukocytes, Mononuclear; Male; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Thymine Nucleotides; Zidovudine | 2008 |
Enzymatic characterization of human immunodeficiency virus type 1 reverse transcriptase resistant to multiple 2',3'-dideoxynucleoside 5'-triphosphates.
Topics: Antiviral Agents; Base Sequence; Binding Sites; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Dideoxynucleotides; DNA Primers; DNA, Viral; Drug Resistance, Multiple; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Thymine Nucleotides; Zidovudine | 1995 |
3'-Azido-3'-deoxythymidine potently inhibits protein glycosylation. A novel mechanism for AZT cytotoxicity.
Topics: Animals; CHO Cells; Cricetinae; Cytidine Monophosphate N-Acetylneuraminic Acid; Dideoxynucleotides; Glycosylation; Golgi Apparatus; HIV; HIV Infections; Humans; Intracellular Membranes; Kinetics; Membrane Proteins; Nucleoside Diphosphate Sugars; Protein Processing, Post-Translational; Thymine Nucleotides; Uridine Diphosphate Galactose; Uridine Diphosphate N-Acetylglucosamine; Zidovudine | 1994 |
Evidence of in vitro development of drug resistance to azidothymidine in T-lymphocytic leukemia cell lines (Jurkat E6-1/AZT-100) and in pediatric patients with HIV-1 infection.
Topics: Adolescent; Adult; Antiviral Agents; Cell Division; Child; Child, Preschool; Clone Cells; Dideoxynucleotides; DNA, Neoplasm; Drug Resistance; Drug Resistance, Microbial; HIV Infections; HIV-1; Humans; Infant; Leukemia, T-Cell; T-Lymphocytes; Thymidine Kinase; Thymine Nucleotides; Tumor Cells, Cultured; Zidovudine | 1993 |
Systemic pharmacokinetics and cellular pharmacology of zidovudine in human immunodeficiency virus type 1-infected women and newborn infants.
Topics: Adolescent; Adult; Anti-HIV Agents; Dideoxynucleotides; Female; Fetal Blood; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Phosphorylation; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Zidovudine | 1999 |
Simultaneous quantitation of intracellular zidovudine and lamivudine triphosphates in human immunodeficiency virus-infected individuals.
Topics: Anti-HIV Agents; Chromatography, Ion Exchange; Cytidine Triphosphate; Dideoxynucleotides; HIV Infections; Humans; Lamivudine; Reference Standards; Thymine Nucleotides; Zidovudine | 2000 |
Simultaneous quantitation of the 5'-triphosphate metabolites of zidovudine, lamivudine, and stavudine in peripheral mononuclear blood cells of HIV infected patients by high-performance liquid chromatography tandem mass spectrometry.
Topics: Anti-HIV Agents; Calibration; Chromatography, High Pressure Liquid; Cytidine Triphosphate; Dideoxynucleotides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Mass Spectrometry; Monocytes; Reference Standards; Sensitivity and Specificity; Stavudine; Thymine Nucleotides; Zidovudine | 2000 |
Zidovudine phosphorylation determined sequentially over 12 months in human immunodeficiency virus-infected patients with or without previous exposure to antiretroviral agents.
Topics: Adult; Anti-HIV Agents; Dideoxynucleotides; Female; HIV; HIV Infections; Humans; Longitudinal Studies; Male; Middle Aged; Phosphorylation; Thymine Nucleotides; Zidovudine | 2001 |
Phosphorylated zidovudine concentrations in mononuclear cells in pediatric patients with human immunodeficiency virus infections.
Topics: Adolescent; Anti-HIV Agents; Biological Availability; Child; Child, Preschool; Dideoxynucleotides; Dose-Response Relationship, Drug; Female; HIV Infections; Humans; Male; Monocytes; Phosphorylation; Thymine Nucleotides; Treatment Outcome; Zidovudine | 1997 |
Inhibition of purified recombinant reverse transcriptase from wild-type and zidovudine-resistant clinical isolates of human immunodeficiency virus type 1 by zidovudine, stavudine, and lamivudine triphosphates.
Topics: Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Escherichia coli; HIV Infections; HIV-1; Lamivudine; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Stavudine; Thymine Nucleotides; Transfection; Zidovudine | 2001 |
Intracellular zidovudine (ZDV) and ZDV phosphates as measured by a validated combined high-pressure liquid chromatography-radioimmunoassay procedure.
Topics: Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Dideoxynucleotides; Drug Stability; HIV Infections; Humans; Intracellular Fluid; Leukocytes, Mononuclear; Phosphorylation; Radioimmunoassay; Reproducibility of Results; Sensitivity and Specificity; Thymine Nucleotides; Tritium; Zidovudine | 1992 |
Intracellular metabolism of 3'-azidothymidine in isolated human peripheral blood mononuclear cells.
Topics: Adult; Dideoxynucleotides; Female; Half-Life; HIV Infections; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Male; Middle Aged; Phosphorylation; Phytohemagglutinins; Thymine Nucleotides; Zidovudine | 1991 |