zidovudine has been researched along with Liver Dysfunction in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (63.64) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bentley, AT; Lynx, MD; McKee, EE | 1 |
| Abdoulaye, D; André, C; André, E; Bernard, L; Sandrine, PF; Sylvie, A | 1 |
| Ali, IY; Gaikwad, AB; Gupta, J; Tamta, A; Tikoo, K | 1 |
| Bareggi, SR; Cinque, P; D'Arminio, A; Lazzarin, A; Mazzei, M; Nicolin, A; Pirola, R; Ruggieri, A | 1 |
| Crofton, ME; Goldin, R; Wetton, CW | 1 |
| Brouwer, KL; Cheeseman, SH; Eyster, E; Lemon, SM; Moore, KH; Opheim, K; Raasch, RH; van der Horst, CM | 1 |
| Borucki, MJ; Haque, AK; Olano, JP; Wen, JW | 1 |
| Abad, M; Alonso, MJ; Corcuera, T; Gómez, F; López-Bravo, A; Muñoz, E; Picazo, A; Roldán, M | 1 |
| Espiridião SKulay, L; Mamede, JA; Mora, OA; Oliveira-Filho, RM; Simo s, MJ | 1 |
| Balfour, HH; Beatty, CC; Fletcher, CV; Rhame, FS; Simpson, M | 1 |
| Smallwood, R | 1 |
1 review(s) available for zidovudine and Liver Dysfunction
| Article | Year |
|---|---|
AIDS and the gastroenterologist.
Topics: Acquired Immunodeficiency Syndrome; Animals; Candidiasis; Cryptosporidium; Cytomegalovirus Infections; Digestive System; Gastrointestinal Diseases; Gastrointestinal Neoplasms; Herpes Simplex; Humans; Liver Diseases; Lymphoma; Nutritional Physiological Phenomena; Opportunistic Infections; Sarcoma, Kaposi; Zidovudine | 1990 |
2 trial(s) available for zidovudine and Liver Dysfunction
| Article | Year |
|---|---|
Pharmacokinetics of zidovudine in HIV-positive patients with liver disease.
Topics: Adult; Half-Life; HIV Infections; HIV Seropositivity; Humans; Liver Diseases; Metabolic Clearance Rate; Zidovudine | 1994 |
Pharmacokinetics and bioavailability of zidovudine and its glucuronidated metabolite in patients with human immunodeficiency virus infection and hepatic disease (AIDS Clinical Trials Group protocol 062).
Topics: Administration, Oral; Adult; Antiviral Agents; Biological Availability; Female; HIV Infections; Humans; Injections, Intravenous; Liver Diseases; Male; Middle Aged; Zidovudine | 1995 |
8 other study(ies) available for zidovudine and Liver Dysfunction
| Article | Year |
|---|---|
3'-Azido-3'-deoxythymidine (AZT) inhibits thymidine phosphorylation in isolated rat liver mitochondria: a possible mechanism of AZT hepatotoxicity.
Topics: Animals; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; In Vitro Techniques; Kinetics; Liver Diseases; Mitochondria, Liver; Phosphorylation; Rats; Rats, Sprague-Dawley; Thymidine; Zidovudine | 2006 |
Nodular regenerative hyperplasia: a new serious antiretroviral drugs side effect?
Topics: Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Chemical and Drug Induced Liver Injury; Didanosine; Female; HIV Infections; HIV-1; Humans; Hyperplasia; Liver; Liver Diseases; Liver Regeneration; Middle Aged; Nevirapine; Zidovudine | 2007 |
Tannic acid prevents azidothymidine (AZT) induced hepatotoxicity and genotoxicity along with change in expression of PARG and histone H3 acetylation.
Topics: Acetylation; Alanine Transaminase; Alkaline Phosphatase; Animals; Anti-HIV Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; DNA Damage; Glycoside Hydrolases; Histones; Liver; Liver Diseases; Malondialdehyde; Mice; Micronucleus Tests; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Tannins; Zidovudine | 2008 |
Periportal fibrosis secondary to transfusion siderosis in two patients with acquired immune deficiency syndrome (AIDS) treated with zidovudine--a confusing ultrasound appearance.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anemia; Fibrosis; Humans; Liver Diseases; Male; Portal System; Siderosis; Transfusion Reaction; Ultrasonography; Zidovudine | 1993 |
Massive hepatic steatosis and lactic acidosis in a patient with AIDS who was receiving zidovudine.
Topics: Acidosis, Lactic; Acquired Immunodeficiency Syndrome; Adult; Alanine Transaminase; Bilirubin; Chemical and Drug Induced Liver Injury; Fat Necrosis; Fatal Outcome; Female; Humans; L-Lactate Dehydrogenase; Liver Diseases; Zidovudine | 1995 |
Hepatic Morphological alterations induced by zidovudine (ZDV) in an experimental model.
Topics: Animals; Chemical and Drug Induced Liver Injury; Liver; Liver Diseases; Microscopy, Electron; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Time Factors; Zidovudine | 1996 |
Hepatic and renal effects of azidothymidine and acyclovir on pregnant rats.
Topics: Abortion, Spontaneous; Acyclovir; Animals; Antiviral Agents; Chemical and Drug Induced Liver Injury; Drug Synergism; Female; Kidney; Kidney Diseases; Liver; Liver Diseases; Pregnancy; Pregnancy Complications; Rats; Rats, Wistar; Zidovudine | 2000 |
Comparative pharmacokinetics of zidovudine in healthy volunteers and in patients with AIDS with and without hepatic disease.
Topics: Absorption; Acquired Immunodeficiency Syndrome; Administration, Oral; Humans; Liver Diseases; Liver Function Tests; Metabolic Clearance Rate; Models, Biological; Radioimmunoassay; Zidovudine | 1992 |