Compounds > zidovudine
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zidovudine and Leucocythaemia

zidovudine has been researched along with Leucocythaemia in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's4 (40.00)18.2507
2000's2 (20.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, C; Chu, HY; Liu, Y; Yuan, LY1
Chen, C; Jia, MF; Li, M; Li, ZJ; Liu, CX; Ma, T; Wang, LN; Xi, YM; Zhang, H; Zhao, L1
Chao, R; Chen, C; Chu, HY; Jin, RR; Li, M; Xi, YM; Zhang, H1
D'Cruz, OJ; Tai, HL; Uckun, FM1
Benyumov, AO; Downs, S; Dumezb, D; Grigoriants, OO; Tibbles, HE; Uckun, FM; Vassilev, AO; Venkatachalam, TK1
Chandrasekaran, B; Duch, DS; Kute, TE1
Arnér, ES; Eriksson, S; Spasokoukotskaja, T1
Coplan, PM; Nolan, LL1
Eble, JN; Hoffman, R; Ichikawa, S; Jayaram, HN; Nagai, M; Nakamura, H; Natsumeda, Y; Paulik, E; Weber, G; Zhen, WN1
Frick, LW; Furman, PA; Krenitsky, TA; Nelson, DJ; St Clair, MH1

Reviews

1 review(s) available for zidovudine and Leucocythaemia

ArticleYear
Regulation of de novo and salvage pathways in chemotherapy.
    Advances in enzyme regulation, 1991, Volume: 31

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cell Line; Humans; Leukemia; Pyrimidines; Ribavirin; Thymidine Kinase; Thymidylate Synthase; Zidovudine

1991

Other Studies

9 other study(ies) available for zidovudine and Leucocythaemia

ArticleYear
[Effects of the Combination of Emodin and 3'-Azido-3'-Deoxythymidine on Proliferation and Apoptosis in leukemia KG-1a cells Transfected with Egr-1 siRNA].
    Zhongguo shi yan xue ye xue za zhi, 2015, Volume: 23, Issue:2

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Early Growth Response Protein 1; Emodin; Flow Cytometry; Humans; Leukemia; RNA, Small Interfering; Transfection; Zidovudine

2015
[Effect of Emodin Combined with AZT on the Proliferation and the Expression of BCL-2, NF-κB, TGF-β in the Leukemia Stem Cells-KG-1a cells].
    Zhongguo shi yan xue ye xue za zhi, 2015, Volume: 23, Issue:5

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Emodin; Humans; Leukemia; Neoplastic Stem Cells; NF-kappa B p50 Subunit; Proto-Oncogene Proteins c-bcl-2; Transforming Growth Factor beta1; Zidovudine

2015
[Effects of AZT on leukemia cell line KG-1a proliferation and telomerase activity].
    Zhongguo shi yan xue ye xue za zhi, 2012, Volume: 20, Issue:2

    Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Humans; Leukemia; Telomerase; Zidovudine

2012
Antileukemic activity and cellular metabolism of the aryl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07).
    Arzneimittel-Forschung, 2005, Volume: 55, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Biotransformation; Carboxylic Ester Hydrolases; Cell Division; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Dideoxynucleotides; Drug Resistance, Multiple; Embryo, Nonmammalian; Glutathione; Humans; Leukemia; Nucleosides; Paraoxon; Rhodamine 123; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Thymidine Monophosphate; Tumor Stem Cell Assay; Zebrafish; Zidovudine

2005
Anti-proliferative and anti-leukemic activity of DDE46 (compound WHI-07), a novel bromomethoxylated arylphosphate derivative of zidovudine, and related compounds. Studies using human acute lymphoblastic leukemia cells and the zebrafish model.
    Arzneimittel-Forschung, 2005, Volume: 55, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase Inhibitors; Cell Proliferation; Dideoxynucleotides; Drug Screening Assays, Antitumor; Humans; Jurkat Cells; Leukemia; Magnetic Resonance Spectroscopy; Nephelometry and Turbidimetry; Prodrugs; Tetrazolium Salts; Thiazoles; Thymidine Monophosphate; Tubulin; Zebrafish; Zidovudine

2005
Synchronization of cells in the S phase of the cell cycle by 3'-azido-3'-deoxythymidine: implications for cell cytotoxicity.
    Cancer chemotherapy and pharmacology, 1995, Volume: 35, Issue:6

    Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Division; Cell Survival; Colonic Neoplasms; Computer Simulation; DNA, Neoplasm; Drug Synergism; Flow Cytometry; Fluorouracil; Humans; Leukemia; Melanoma; Methotrexate; Pancreatic Neoplasms; S Phase; Tumor Cells, Cultured; Zidovudine

1995
Selective assays for thymidine kinase 1 and 2 and deoxycytidine kinase and their activities in extracts from human cells and tissues.
    Biochemical and biophysical research communications, 1992, Oct-30, Volume: 188, Issue:2

    Topics: Arabinonucleosides; Cladribine; Deoxycytidine; Deoxycytidine Kinase; Humans; Isoenzymes; Kinetics; Leukemia; Leukocytes; Mitochondria; Organ Specificity; Phosphorylation; Radioisotope Dilution Technique; Reference Values; Substrate Specificity; Thymidine; Thymidine Kinase; Tritium; Tumor Cells, Cultured; Zidovudine

1992
The selective toxicity of medications used in the treatment of AIDS on the CEM human leukemic CD4+ T-cell line.
    Drug and chemical toxicology, 1991, Volume: 14, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4-Positive T-Lymphocytes; Didanosine; Humans; Leukemia; Tumor Cells, Cultured; Zidovudine

1991
Effects of 3'-azido-3'-deoxythymidine on the deoxynucleotide triphosphate pools of cultured human cells.
    Biochemical and biophysical research communications, 1988, Jul-15, Volume: 154, Issue:1

    Topics: Antiviral Agents; Cell Line; Deoxyribonucleotides; Humans; Kinetics; Leukemia; Thymidine; Zidovudine

1988