Page last updated: 2024-08-23

zidovudine and Delayed Effects, Prenatal Exposure

zidovudine has been researched along with Delayed Effects, Prenatal Exposure in 78 studies

Research

Studies (78)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.28)18.7374
1990's19 (24.36)18.2507
2000's40 (51.28)29.6817
2010's18 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blanche, S; Clavel, J; Dollfus, C; Faye, A; Goujon, S; Hleyhel, M; Mandelbrot, L; Sibiude, J; Tubiana, R; Warszawski, J1
Dugange, F; Harms, G; Hauser, A; Kirschner, W; Kunz, A; Lau, I; Sewangi, J; Theuring, S; Ziske, J1
André-Schmutz, I; Azria, E; Benachi, A; Blanche, S; Bouallag, N; Cagnard, N; Cavazzana, M; Cocchiarella, F; Cordier, AG; Dal-Cortivo, L; Kaltenbach, S; Le Chenadec, J; Leschi, C; Luce, S; Mandelbrot, L; Mavilio, F; Radford-Weiss, I; Recchia, A; Reimann, C; Revy, P; Six, E; Ternaux, B1
Drzazga, Z; Kaszuba, M; Maciejewska, K1
Albano, J; Gee, C; Koram, N; Tilson, H; Vannappagari, V1
Albano, JD; Koram, N; Napier, MD; Scheuerle, AE; Tilson, H; Vannappagari, V1
Divi, RL; Gibbons, AT; Liu, Y; Poirier, MC; Shide, ED; Shim Park, E; Woodward, RA1
Cardellach, F; Catalán-García, M; Coll, O; García-Otero, L; Garrabou, G; Gratacós, E; Guitart-Mampel, M; Hernández, S; López, M; Milisenda, J; Miró, Ò; Morén, C1
Bae, WH; Essex, M; Lockman, S; Onyait, K; Shapiro, RL; Smeaton, LM; Thior, I; Wester, C1
Hong, HH; Koujitani, T; Lahousse, SA; Sills, RC; Ton, TV; Wakamatsu, N1
Aldrovandi, GM; Chu, C; Foca, M; Ha, BF; Li, D; McIntosh, K; Meyer, WA; Moye, J; Rich, KC; Shearer, WT; Thompson, B; Walter, J1
Carter, MM; March, TH; McCash, CL; Poirier, MC; Seilkop, SK; Torres, SM; Walker, DM; Walker, VE1
Campen, MJ; Carter, MM; Chu, Y; Divi, RL; Einem, TL; Kang, H; McCash, CL; Poirier, MC; Seilkop, SK; Torres, SM; Walker, DM; Walker, VE1
Borum, PR; Brogly, SB; Chernoff, MC; Crain, MJ; Ford-Chatterton, HM; Malee, KM; Meyer, WA; Mitchell, WG; Moye, JH; Oleske, JM; Seage Iii, GR; Van Dyke, RB1
Baroncelli, S; Floridia, M; Genovese, O; Pinnetti, C; Tamburrini, E1
Dryden-Peterson, S; Essex, M; Hughes, MD; Lockman, S; Makhema, J; Moffat, C; Moyo, S; Ogwu, A; Powis, K; Shapiro, RL1
Bhattacharyya, A; Pandey, BL; Rai, AK; Rajlakshmi, C; Roy, JK1
Colan, SD; Mittleman, MA; Oleske, JM; Patel, K; Seage, GR; Van Dyke, RB1
Aloe, L; Calamandrei, G; Puopolo, M; Valanzano, A1
Alleva, E; Capone, F; Cirulli, F; Venerosi, A1
Ayers, L1
Al-Harthi, L; Blattner, WA; Charurat, M; Divi, RL; Landay, AL; Nguyen, V; Olivero, OA; Poirier, MC; Walker, B; Walker, VE1
Bishop, JB; Tice, RR; Witt, KL; Wolfe, GW2
Abrams, EJ; Adams, ME; Divi, RL; Nagashima, K; Nesel, CJ; O'Neill, JP; Poirier, MC; Seilkop, SK; Wade, NA; Walker, VE1
Abduch, R; Duarte, G; El Beitune, P; Figueiró-Filho, EA; Marcolin, AC; Quintana, SM1
Duarte, G; El Beitune, P; Figueiró-Filho, EA; Foss, MC; Montenegro, RM; Nogueira, AA; Quintana, SM1
Ball, W; Barret, B; Blanche, S; Brunelle, F; Lachassine, E; Mayaux, MJ; Pautard, B; Raybaud, C; Tardieu, M1
Ashley, N; Clark, A; Field, P; Harris, D; Hartley, M; Morten, K; Poulton, J; Williams, KA1
Chiapello, N; Gabiano, C; Spada, M; Tovo, PA; Zeviani, M1
Bhakeecheep, S; Briand, N; Hansudewechakul, R; Hongsiriwon, S; Ithisukanan, J; Karnchanamayul, V; Lallemant, M; Le Coeur, S; McIntosh, K; Ngampiyasakul, C; Traisathit, P1
Venhoff, N; Walker, UA1
Benhammou, V; Blanche, S; Rustin, P; Tardieu, M; Warszawski, J1
Dabis, F; Elenga, N; Fassinou, P; Msellati, P; Viho, I1
Blanche, S1
Abzug, MJ; Brady, M; Brogly, SB; Crain, MJ; Hughes, MD; Jean-Philippe, P; Mofenson, LM; Oleske, J; Seage, GR; Van Dyke, R; Ylitalo, N1
Blanche, S; Cibert, C; Costagliola, D; Firtion, G; Floch, C; Nigon, F; Parat, S; Senda, S; Viegas-Péquignot, E1
Gibb, DM; Newell, ML1
Cobb, JR; Etemadi, AA; Jones, TM; Lemon, T; Majekodunmi, MJ; Urso, P; Wirsiy, YG1
Andrews, E; Eldridge, R; White, A1
Ayers, KM; Reynolds, DJ; Torrey, CE1
Csete, B; Faludi, B; Hajnal, A; Jandó, G; Lénád, L; Petykó, Z; Sümegi, B1
Abkowitz, JL; Conrad, SH; Ha, JC; Mottet, NK; Nosbisch, C; Robinette, R; Ruppenthal, GC; Sackett, GP; Unadkat, JD1
Nersesyan, AK1
Anderson, LM; Diwan, BA; Haines, DC; Logsdon, D; Olivero, OA; Poirier, MC; Rice, JM; Yuspa, SH; Zhang, Z1
Brady, M; Culnane, M; Cunningham, B; Diaz, C; Flynn, PM; Fowler, M; Gortmaker, SL; Jimenez, E; Lee, SS; McSherry, G; Mofenson, L; Moore, EC; O'Donnell, K; Oleske, J; Scott, G; Shapiro, DE1
Alleva, E; Branchi, I; Calamandrei, G; Venerosi, A1
Agostoni, C; D'Auria, E; Riva, E; Torcoletti, M; Zuccotti, GV1
Alleva, E; Branchi, I; Calamandrei, G; Rondinini, C; Venerosi, A1
Barret, B; Blanche, S; Ciraru-Vigneron, N; Delfraissy, JF; Desguerre, I; Firtion, G; Lacroix, C; Mandelbrot, L; Mayaux, MJ; Rötig, A; Rouzioux, C; Rustin, P; Slama, A; Tardieu, M1
Fowler, MG1
Diwan, BA; Olivero, OA; Poirier, MC1
Baker, R; Chougnet, C; Kovacs, A; Liewehr, DJ; Luban, NL; Mueller, BU; Shearer, GM; Steinberg, SM; Thomas, EK1
Ewings, EL; Gerschenson, M; Harbaugh, JW; Harbaugh, SW; Nagashima, K; Poirier, MC; Skopets, B; St Claire, MC1
de Souza, RS; Gómez-Marín, O; Guasti, S; Mitchell, CD; O'Sullivan, MJ; Oliveira, RH; Scott, GB1
Anderson, CE; Cocroft, J; Hauck, WW; Newschaffer, CJ; Turner, BJ1
Belohradsky, BH; Rolinski, B; Stojanov, S; Wintergerst, U1
Bricker, JT; Colan, SD; Easley, KA; Kaplan, S; Lai, WW; Lipshultz, SE; McIntosh, K; Moodie, DS; Orav, EJ; Sopko, G; Starc, TJ1
Mofenson, LM1
Moschovi, M; Papaevangelou, V; Theodoridou, M; Tzortzatou-Stathopoulou, F1
Fleming, P; Gordon, L; Lindegren, ML; Rhodes, P1
Haas, RH1
Mirochnick, M1
Alleva, E; Calamandrei, G; Valanzano, A; Venerosi, A2
Lewis, W1
Alleva, E; Ricceri, L; Sorace, A; Valanzano, A; Venerosi, A1
Highleyman, L1
Eriksen, N1
Cotton, MF; Pieper, CH; Rabie, H; Robson, B1
Jaenisch, R; Ruprecht, RM; Sharpe, AH1

Reviews

4 review(s) available for zidovudine and Delayed Effects, Prenatal Exposure

ArticleYear
Antiretroviral therapy during pregnancy and early neonatal life: consequences for HIV-exposed, uninfected children.
    The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, 2004, Volume: 8, Issue:2

    Topics: Anti-HIV Agents; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Zidovudine

2004
Mitochondrial disease in the offspring as a result of antiretroviral therapy.
    Expert opinion on drug safety, 2006, Volume: 5, Issue:3

    Topics: Animals; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Female; HIV Infections; Humans; Infant, Newborn; Mitochondrial Diseases; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Zidovudine

2006
A risk-benefit assessment of zidovudine in the prevention of perinatal HIV transmission.
    Drug safety, 1995, Volume: 12, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Animals; Drug Resistance, Microbial; Female; Guidelines as Topic; HIV; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Randomized Controlled Trials as Topic; Risk Assessment; Zidovudine

1995
Follow-up of children exposed to perinatal antiretrovirals.
    Teratology, 2000, Volume: 61, Issue:5

    Topics: Anemia; Anti-HIV Agents; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Pregnancy; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Zidovudine

2000

Trials

6 trial(s) available for zidovudine and Delayed Effects, Prenatal Exposure

ArticleYear
Hematologic and hepatic toxicities associated with antenatal and postnatal exposure to maternal highly active antiretroviral therapy among infants.
    AIDS (London, England), 2008, Aug-20, Volume: 22, Issue:13

    Topics: Alanine Transaminase; Anti-HIV Agents; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Aspartate Aminotransferases; Biomarkers; Botswana; Breast Feeding; Cohort Studies; Female; Follow-Up Studies; Hemoglobins; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Neutropenia; Nevirapine; Platelet Count; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Zidovudine

2008
Increased risk of severe infant anemia after exposure to maternal HAART, Botswana.
    Journal of acquired immune deficiency syndromes (1999), 2011, Apr-15, Volume: 56, Issue:5

    Topics: Adult; Anemia; Antiretroviral Therapy, Highly Active; Botswana; Breast Feeding; Female; HIV Infections; HIV-1; Humans; Incidence; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Perinatal Care; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Severity of Illness Index; Treatment Outcome; Zidovudine

2011
Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers.
    Journal of acquired immune deficiency syndromes (1999), 2003, Jun-01, Volume: 33, Issue:2

    Topics: Adult; Child, Preschool; DNA, Mitochondrial; Female; Fetal Blood; Genetic Markers; HIV Infections; Humans; Infant; Infant, Newborn; Leukocytes, Mononuclear; Pilot Projects; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Ribosomal, 18S; Telomere; Zidovudine

2003
Growth of human immunodeficiency virus-uninfected children exposed to perinatal zidovudine for the prevention of mother-to-child human immunodeficiency virus transmission.
    The Pediatric infectious disease journal, 2006, Volume: 25, Issue:4

    Topics: Anti-HIV Agents; Body Height; Body Mass Index; Body Weight; Female; Growth; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Thailand; Zidovudine

2006
In utero nucleoside reverse transcriptase inhibitor exposure and signs of possible mitochondrial dysfunction in HIV-uninfected children.
    AIDS (London, England), 2007, May-11, Volume: 21, Issue:8

    Topics: Anti-HIV Agents; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV Reverse Transcriptase; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Maternal-Fetal Exchange; Mitochondrial Diseases; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Sex Factors; Zidovudine

2007
Lack of long-term effects of in utero exposure to zidovudine among uninfected children born to HIV-infected women. Pediatric AIDS Clinical Trials Group Protocol 219/076 Teams.
    JAMA, 1999, Jan-13, Volume: 281, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Child Development; Child, Preschool; Echocardiography; Female; Growth; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Longitudinal Studies; Male; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Prospective Studies; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Vision Tests; Zidovudine

1999

Other Studies

68 other study(ies) available for zidovudine and Delayed Effects, Prenatal Exposure

ArticleYear
Risk of cancer in children exposed to antiretroviral nucleoside analogues in utero: The french experience.
    Environmental and molecular mutagenesis, 2019, Volume: 60, Issue:5

    Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Didanosine; Female; HIV Infections; Humans; Incidence; Infant; Infant, Newborn; Male; Maternal Exposure; Maternal-Fetal Exchange; Neoplasms; Nucleosides; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Reverse Transcriptase Inhibitors; Risk; Surveys and Questionnaires; Zidovudine

2019
Hematological changes in women and infants exposed to an AZT-containing regimen for prevention of mother-to-child-transmission of HIV in Tanzania.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Anti-HIV Agents; Blood Cell Count; Drug Therapy, Combination; Female; Hematocrit; Hematologic Diseases; Hematologic Tests; Hemoglobins; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Mothers; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Tanzania; Young Adult; Zidovudine

2013
Genotoxic signature in cord blood cells of newborns exposed in utero to a Zidovudine-based antiretroviral combination.
    The Journal of infectious diseases, 2013, Jul-15, Volume: 208, Issue:2

    Topics: Adult; Anti-HIV Agents; Antigens, CD34; Cell Cycle; DNA Repair; Drug Combinations; Female; Fetal Blood; Gene Expression Profiling; Hematopoietic Stem Cells; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Karyotyping; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Stem Cells; Transcriptome; Young Adult; Zidovudine

2013
Toxicology and carcinogenesis of 3´-azido-3´-deoxythymidine (AZT) (CAS No. 30516-87-1) in genetically modified C3B6.129F1-Trp53(tm1Brd) N12 haploinsufficient mice (in utero and postnatal gavage studies).
    National Toxicology Program genetically modified model report, 2013, Issue:14

    Topics: Animals; Anti-HIV Agents; Carcinogens; Female; Genes, p53; Haploinsufficiency; Humans; Liver Neoplasms, Experimental; Lymphoma; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine

2013
Toxicology and Carcinogenesis Studies of Mixtures of 3'-Azido-3'-Deoxythymidine (AZT), Lamivudine (3TC), and Nevirapine (NVP) (CAS Nos. 30516-87-1, 134678-17-4, 129618-40-2) in Genetically Modified C3B6.129F1-Trp53(tm1Brd) N12 Haploinsufficient Mice (in u
    National Toxicology Program genetically modified model report, 2013, Issue:16

    Topics: Animals; Animals, Genetically Modified; Animals, Newborn; Anti-HIV Agents; Body Weight; Chemistry, Pharmaceutical; Drug Combinations; Female; Haploinsufficiency; Intubation, Gastrointestinal; Lamivudine; Litter Size; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mutagens; Nevirapine; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Reproduction; Reverse Transcriptase Inhibitors; Survival; Zidovudine

2013
The changes in bone organic and inorganic matrix in newborn rats after maternal application of antiretroviral agents: Indinavir and zidovudine.
    BioFactors (Oxford, England), 2015, May-06, Volume: 41, Issue:3

    Topics: Animals; Anti-Retroviral Agents; Bone Density; Calcium; Female; Femur; Humans; Incisor; Indinavir; Mandible; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Skull; Tibia; Trace Elements; Zidovudine

2015
Association between in utero zidovudine exposure and nondefect adverse birth outcomes: analysis of prospectively collected data from the Antiretroviral Pregnancy Registry.
    BJOG : an international journal of obstetrics and gynaecology, 2016, Volume: 123, Issue:6

    Topics: Abortion, Induced; Abortion, Spontaneous; Adolescent; Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Infant, Low Birth Weight; Live Birth; Middle Aged; Pregnancy; Pregnancy Complications, Infectious; Premature Birth; Prenatal Exposure Delayed Effects; Prevalence; Registries; Risk Factors; Stillbirth; Young Adult; Zidovudine

2016
Prenatal exposure to zidovudine and risk for ventricular septal defects and congenital heart defects: data from the Antiretroviral Pregnancy Registry.
    European journal of obstetrics, gynecology, and reproductive biology, 2016, Volume: 197

    Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Argentina; Brazil; Case-Control Studies; Female; France; Gestational Age; Heart Defects, Congenital; Heart Septal Defects, Ventricular; HIV Infections; Humans; Live Birth; Middle Aged; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Second; Prenatal Exposure Delayed Effects; Prevalence; Prospective Studies; Registries; Risk Factors; South Africa; Uganda; United Kingdom; United States; Young Adult; Zidovudine

2016
Mitochondrial compromise in 3-year old patas monkeys exposed in utero to human-equivalent antiretroviral therapies.
    Environmental and molecular mutagenesis, 2016, Volume: 57, Issue:7

    Topics: Animals; Anti-HIV Agents; Bone Marrow Cells; Brain; Dideoxynucleosides; DNA, Mitochondrial; Drug Therapy, Combination; Erythrocebus patas; Female; Gestational Age; Heart; Lamivudine; Mitochondria; Mitochondria, Heart; Oxygen Consumption; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine

2016
Placental Mitochondrial Toxicity, Oxidative Stress, Apoptosis, and Adverse Perinatal Outcomes in HIV Pregnancies Under Antiretroviral Treatment Containing Zidovudine.
    Journal of acquired immune deficiency syndromes (1999), 2017, 08-01, Volume: 75, Issue:4

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Apoptosis; Case-Control Studies; Contraindications; Cross-Sectional Studies; DNA, Mitochondrial; Female; Fetal Blood; HIV Infections; Humans; Infant, Newborn; Infant, Small for Gestational Age; Infectious Disease Transmission, Vertical; Maternal-Fetal Exchange; Oxidative Stress; Placenta; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Spain; Zidovudine

2017
K-ras cancer gene mutations in lung tumors from female Swiss (CD-1) mice exposed transplacentally to 3'-azido-3'-deoxythymidine.
    Environmental and molecular mutagenesis, 2008, Volume: 49, Issue:9

    Topics: Animals; Female; Genes, ras; Lung Neoplasms; Male; Maternal Exposure; Mice; Mutation; Pregnancy; Prenatal Exposure Delayed Effects; Sex Factors; Zidovudine

2008
Antiretroviral exposure and lymphocyte mtDNA content among uninfected infants of HIV-1-infected women.
    Pediatrics, 2009, Volume: 124, Issue:6

    Topics: Anti-HIV Agents; DNA, Mitochondrial; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Longitudinal Studies; Monocytes; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; Prenatal Exposure Delayed Effects; Reference Values; Reverse Transcriptase Inhibitors; Zidovudine

2009
In utero exposure of female CD-1 Mice to AZT and/or 3TC: I. Persistence of microscopic lesions in cardiac tissue.
    Cardiovascular toxicology, 2010, Volume: 10, Issue:1

    Topics: Animals; Anti-HIV Agents; DNA, Mitochondrial; Drug Interactions; Echocardiography; Female; Fetus; Heart; Lamivudine; Male; Maternal-Fetal Exchange; Mice; Microscopy, Electron, Transmission; Mitochondria, Heart; Mutation; Myocardium; Organ Size; Oxidative Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Sex Characteristics; Zidovudine

2010
In utero exposure of female CD-1 mice to AZT and/or 3TC: II. Persistence of functional alterations in cardiac tissue.
    Cardiovascular toxicology, 2010, Volume: 10, Issue:2

    Topics: Animals; Anti-HIV Agents; DNA, Mitochondrial; Drug Interactions; Drug Therapy, Combination; Echocardiography; Electron Transport Chain Complex Proteins; Electrophoresis, Polyacrylamide Gel; Female; Heart; Lamivudine; Luminescent Measurements; Maternal Exposure; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Microscopy, Electron, Transmission; Mitochondria, Heart; Myocardium; Oxidative Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Time Factors; Zidovudine

2010
Possible mitochondrial dysfunction and its association with antiretroviral therapy use in children perinatally infected with HIV.
    The Journal of infectious diseases, 2010, Jul-15, Volume: 202, Issue:2

    Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Cohort Studies; Female; HIV Infections; Humans; Infant, Newborn; Male; Mitochondrial Diseases; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Regression Analysis; Stavudine; United States; Zidovudine

2010
Hematological effects of zidovudine prophylaxis in newborn infants with and without prenatal exposure to zidovudine.
    Journal of medical virology, 2011, Volume: 83, Issue:3

    Topics: Anti-HIV Agents; Antibiotic Prophylaxis; Female; Hematologic Tests; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Treatment Outcome; Zidovudine

2011
An unusual phenotypic and genotypic expression in F2 generation following one stage zidovudine exposure during pregnancy and lactation- an experiment in mice.
    The Journal of toxicological sciences, 2012, Volume: 37, Issue:1

    Topics: Abdominal Fat; Animals; Anti-HIV Agents; Bone Marrow Cells; Chromosome Aberrations; Female; Genes, Recessive; Lactation; Liver; Male; Maternal-Fetal Exchange; Mice; Mutagens; Mutation; Phenotype; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine

2012
The impact of HAART on cardiomyopathy among children and adolescents perinatally infected with HIV-1.
    AIDS (London, England), 2012, Oct-23, Volume: 26, Issue:16

    Topics: Adolescent; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cardiomyopathies; Cardiotonic Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Cohort Studies; Digoxin; Female; Follow-Up Studies; HIV Seropositivity; Humans; Infant; Infectious Disease Transmission, Vertical; Male; Pregnancy; Prenatal Exposure Delayed Effects; Proportional Hazards Models; Prospective Studies; Treatment Outcome; United States; Zalcitabine; Zidovudine

2012
Toxicology and carcinogenesis studies of mixtures of 3'-azido-3'-deoxythymidine (AZT), lamivudine (3TC), nevirapine (NVP), and nelfinavir mesylate (NFV) (Cas Nos. 30516-87-1, 134678-17-4, 129618-40-2, 159989-65-8) in B6C3F1 Mice (transplacental exposure s
    National Toxicology Program technical report series, 2013, Issue:569

    Topics: Administration, Oral; Animals; Anti-Retroviral Agents; DNA; Drug Therapy, Combination; Escherichia coli; Female; Lamivudine; Longevity; Male; Maternal Exposure; Mice; Mice, Inbred Strains; Nelfinavir; Nevirapine; Pregnancy; Prenatal Exposure Delayed Effects; Salmonella typhimurium; Skin Neoplasms; Zidovudine

2013
Developmental exposure to the antiretroviral drug zidovudine increases brain levels of brain-derived neurotrophic factor in mice.
    Neuroscience letters, 2002, Nov-22, Volume: 333, Issue:2

    Topics: Age Factors; Animals; Animals, Newborn; Antimetabolites; Brain; Brain-Derived Neurotrophic Factor; Female; Male; Mice; Nerve Growth Factor; Pregnancy; Prenatal Exposure Delayed Effects; Sex Factors; Time Factors; Zidovudine

2002
Prolonged perinatal AZT administration and early maternal separation: effects on social and emotional behaviour of periadolescent mice.
    Pharmacology, biochemistry, and behavior, 2003, Volume: 74, Issue:3

    Topics: Animals; Animals, Newborn; Corticosterone; Emotions; Female; Male; Maternal Exposure; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Social Behavior; Zidovudine

2003
Is mama a criminal? An analysis of potential criminal liability of HIV-infected pregnant women in the context of mandated drug therapy.
    Drake law review, 2002, Volume: 50, Issue:2

    Topics: Child; Child Advocacy; Coercion; Criminal Law; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Liability, Legal; Mandatory Testing; Patient Compliance; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Privacy; Treatment Refusal; United States; Zidovudine

2002
Genetic damage detected in CD-1 mouse pups exposed perinatally to 3'-azido-3'-deoxythymidine and dideoxyinosine via maternal dosing, nursing, and direct gavage.
    Environmental and molecular mutagenesis, 2004, Volume: 43, Issue:1

    Topics: Administration, Oral; Animals; Anti-HIV Agents; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythrocytes; Female; Lactation; Male; Mice; Mice, Inbred Strains; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Pregnancy; Prenatal Exposure Delayed Effects; Time Factors; Zidovudine

2004
Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir.
    AIDS (London, England), 2004, Apr-30, Volume: 18, Issue:7

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; DNA, Mitochondrial; Drug Combinations; Female; Fetal Blood; HIV Infections; HIV-1; Humans; Infant, Newborn; Lamivudine; Maternal-Fetal Exchange; Microscopy, Electron; Mitochondria; Pilot Projects; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Umbilical Cord; Zidovudine

2004
Genetic damage detected in CD-1 mouse pups exposed perinatally to 3'-azido-3'-deoxythymidine or dideoxyinosine via maternal dosing, nursing, and direct gavage: II. Effects of the individual agents compared to combination treatment.
    Environmental and molecular mutagenesis, 2004, Volume: 44, Issue:4

    Topics: Analysis of Variance; Animals; Animals, Newborn; Anti-HIV Agents; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythrocytes; Female; Male; Mice; Mice, Inbred Strains; Micronuclei, Chromosome-Defective; Micronucleus Tests; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine

2004
Effect of maternal use of antiretroviral agents on serum insulin levels of the newborn infant.
    Diabetes care, 2005, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Anti-HIV Agents; Blood Glucose; Cohort Studies; Female; Fetal Blood; Humans; Infant, Newborn; Insulin; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Zidovudine

2005
Cerebral MR imaging in uninfected children born to HIV-seropositive mothers and perinatally exposed to zidovudine.
    AJNR. American journal of neuroradiology, 2005, Volume: 26, Issue:4

    Topics: Anti-HIV Agents; Brain; Child, Preschool; Female; HIV Seropositivity; Humans; Infant; Magnetic Resonance Imaging; Male; Mitochondrial Encephalomyopathies; Mothers; Pilot Projects; Pregnancy; Prenatal Exposure Delayed Effects; Retrospective Studies; Zidovudine

2005
Fetal and neonatal exposure to AZT and low-protein diet affects glucose homeostasis: a model with implications for AIDS prevention.
    American journal of physiology. Endocrinology and metabolism, 2005, Volume: 289, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Animals; Birth Weight; Blood Glucose; Diabetes Mellitus; Diet, Protein-Restricted; DNA, Mitochondrial; Female; Fetal Development; Homeostasis; Insulin; Islets of Langerhans; Litter Size; Liver; Mice; Mice, Inbred C57BL; Models, Animal; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine

2005
Zidovudine administration during pregnancy and mitochondrial disease in the offspring.
    Antiviral therapy, 2005, Volume: 10, Issue:6

    Topics: Anti-HIV Agents; Chemoprevention; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Mitochondrial Diseases; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Zidovudine

2005
Mitochondrial dysfunction following perinatal exposure to nucleoside analogues.
    AIDS (London, England), 2006, Aug-22, Volume: 20, Issue:13

    Topics: Anti-HIV Agents; Child; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Lamivudine; Mitochondrial Diseases; Nervous System Diseases; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Zidovudine

2006
[Zidovudine-associated mitochondriopathy: three possible observations in Abidjan, Côte d'Ivoire].
    Bulletin de la Societe de pathologie exotique (1990), 2004, Volume: 97, Issue:4

    Topics: Adult; Anemia, Hypochromic; Anti-HIV Agents; Cohort Studies; Comorbidity; Cote d'Ivoire; Epilepsy, Generalized; Failure to Thrive; Female; Fetus; Growth Disorders; HIV Infections; Humans; Infant; Male; Mitochondria; Muscle Hypotonia; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Protein-Energy Malnutrition; Psychomotor Disorders; Randomized Controlled Trials as Topic; Zidovudine

2004
[Possible long-term effect of in utero antiretroviral exposure?].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2007, Volume: 14, Issue:6

    Topics: Anti-HIV Agents; Anti-Retroviral Agents; Child; DNA, Mitochondrial; Female; Fetus; Humans; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine

2007
Altered heterochromatin organization after perinatal exposure to zidovudine.
    Antiviral therapy, 2007, Volume: 12, Issue:2

    Topics: Adolescent; Anti-HIV Agents; Case-Control Studies; Cells, Cultured; Child; Child, Preschool; Chromatin Assembly and Disassembly; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 16; Cohort Studies; DNA Methylation; Female; Heterochromatin; HIV Infections; HIV-1; Humans; In Situ Hybridization, Fluorescence; Infant; Infant, Newborn; Leukocytes; Pregnancy; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Time Factors; Zidovudine

2007
Recommendations of the U.S. Public Health Service Task Force on the use of zidovudine to reduce perinatal transmission of human immunodeficiency virus.
    MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports, 1994, Aug-05, Volume: 43, Issue:RR-11

    Topics: Adult; CD4-Positive T-Lymphocytes; Drug Administration Schedule; Female; Fetal Monitoring; Gestational Age; Hematologic Tests; HIV Infections; Humans; Infant; Infant, Newborn; Leukocyte Count; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Randomized Controlled Trials as Topic; Zidovudine

1994
Birth outcomes following zidovudine therapy in pregnant women.
    MMWR. Morbidity and mortality weekly report, 1994, Jun-10, Volume: 43, Issue:22

    Topics: Abnormalities, Drug-Induced; Female; HIV Infections; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Registries; Zidovudine

1994
From the Centers for Disease Control and Prevention. Birth outcomes following zidovudine therapy in pregnant women.
    JAMA, 1994, Jul-06, Volume: 272, Issue:1

    Topics: Abnormalities, Drug-Induced; Female; HIV Infections; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Registries; Zidovudine

1994
Zidovudine as an immunomodulatory agent.
    Cellular and molecular biology (Noisy-le-Grand, France), 1995, Volume: 41 Suppl 1

    Topics: Administration, Oral; Animals; Animals, Newborn; Antibody Formation; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Drug Evaluation; Female; Hemolytic Plaque Technique; Immunologic Deficiency Syndromes; Immunosuppressive Agents; Injections, Intravenous; Lymphocyte Culture Test, Mixed; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; T-Lymphocytes; Zidovudine

1995
Birth outcomes following zidovudine exposure in pregnant women: the Antiretroviral Pregnancy Registry.
    Acta paediatrica (Oslo, Norway : 1992). Supplement, 1997, Volume: 421

    Topics: Abnormalities, Drug-Induced; Anti-HIV Agents; Female; HIV Infections; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Registries; Teratogens; Zidovudine

1997
A transplacental carcinogenicity bioassay in CD-1 mice with zidovudine.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1997, Volume: 38, Issue:2

    Topics: Animals; Anti-HIV Agents; Body Weight; Carcinogenicity Tests; Carcinogens; Carcinoma, Squamous Cell; Female; Male; Mice; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; Radioimmunoassay; Vaginal Neoplasms; Zidovudine

1997
Learning disturbances in offsprings of zidovudine (AZT) treated rats.
    Neurobiology (Budapest, Hungary), 1997, Volume: 5, Issue:1

    Topics: Animals; Anti-HIV Agents; Behavior, Animal; Female; Learning Disabilities; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Zidovudine

1997
Fetal, infant, and maternal toxicity of zidovudine (azidothymidine) administered throughout pregnancy in Macaca nemestrina.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, May-01, Volume: 18, Issue:1

    Topics: Anemia; Animals; Animals, Newborn; Anti-HIV Agents; Area Under Curve; Bone Marrow; Erythrocyte Indices; Erythropoietin; Female; Fetal Death; Fetal Resorption; Fetus; Hematocrit; Hemoglobins; Leukocyte Count; Macaca nemestrina; Organ Size; Placenta; Platelet Count; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Random Allocation; Zidovudine

1998
Re: Transplacental effects of 3'-azido-2',3'-dideoxythymidine (AZT): tumorigenicity in mice and genotoxicity in mice and monkeys.
    Journal of the National Cancer Institute, 1998, Aug-05, Volume: 90, Issue:15

    Topics: Animals; Anti-HIV Agents; Antimetabolites, Antineoplastic; Female; Male; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine

1998
Skin tumorigenesis and Ki-ras and Ha-ras mutations in tumors from adult mice exposed in utero to 3'-azido-2',3'-dideoxythymidine.
    Molecular carcinogenesis, 1998, Volume: 23, Issue:1

    Topics: Animals; Anti-HIV Agents; Female; Genes, ras; Liver Neoplasms; Lung Neoplasms; Mice; Mutation; Pregnancy; Prenatal Exposure Delayed Effects; Skin Neoplasms; Zidovudine

1998
Effects of prenatal zidovudine treatment on learning and memory capacities of preweanling and young adult mice.
    Neurotoxicology, 1999, Volume: 20, Issue:1

    Topics: Animals; Anti-HIV Agents; Avoidance Learning; Body Weight; Chromatography, High Pressure Liquid; Drinking; Eating; Female; Learning; Male; Maze Learning; Memory; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Reproduction; Zidovudine

1999
Infant growth after in utero exposure to zidovudine.
    JAMA, 1999, Aug-11, Volume: 282, Issue:6

    Topics: Anti-HIV Agents; Female; Growth; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Male; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Zidovudine

1999
Long-term effects of prenatal 3'-azido-3'-deoxythymidine (AZT) exposure on intermale aggressive behaviour of mice.
    Psychopharmacology, 1999, Volume: 145, Issue:3

    Topics: Aggression; Animals; Anti-HIV Agents; Female; Male; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine

1999
Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analogues.
    Lancet (London, England), 1999, Sep-25, Volume: 354, Issue:9184

    Topics: Acidosis, Lactic; Anti-HIV Agents; Child, Preschool; DNA, Mitochondrial; Female; France; HIV Infections; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Maternal-Fetal Exchange; Mitochondrial Encephalomyopathies; Pregnancy; Prenatal Exposure Delayed Effects; Reference Values; Retrospective Studies; Zidovudine

1999
Absence of structural or functional alterations in male and female reproductive organs of F1 and F2 generations derived from female mice exposed to 3'-azido-3'-deoxythymidine during pregnancy.
    Toxicology letters, 2000, Apr-10, Volume: 115, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Anti-HIV Agents; Female; Fertility; Genitalia; Male; Mice; Organ Size; Pregnancy; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Zidovudine

2000
Influence of human immunodeficiency virus-infected maternal environment on development of infant interleukin-12 production.
    The Journal of infectious diseases, 2000, Volume: 181, Issue:5

    Topics: Adult; Anti-HIV Agents; Cells, Cultured; Child, Preschool; Cytokines; Female; Fetal Blood; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Interleukin-10; Interleukin-12; Lymphocytes; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Regression Analysis; Tumor Necrosis Factor-alpha; Zidovudine

2000
Genotoxic and functional consequences of transplacental zidovudine exposure in fetal monkey brain mitochondria.
    Journal of acquired immune deficiency syndromes (1999), 2000, Jun-01, Volume: 24, Issue:2

    Topics: Animals; Animals, Newborn; Brain; Cerebellum; DNA, Mitochondrial; Electron Transport Complex II; Erythrocebus patas; Female; Humans; Maternal-Fetal Exchange; Mitochondria; Multienzyme Complexes; Mutagens; NADH Dehydrogenase; Oxidative Phosphorylation; Oxidoreductases; Pregnancy; Prenatal Exposure Delayed Effects; Succinate Dehydrogenase; Zidovudine

2000
Effect of prenatal zidovudine on disease progression in perinatally HIV-1-infected infants.
    Journal of acquired immune deficiency syndromes (1999), 2000, Jun-01, Volume: 24, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Disease Progression; Female; Gestational Age; HIV Infections; HIV Seropositivity; HIV-1; Humans; Infant; Infant, Newborn; Infant, Premature; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Retrospective Studies; Risk Factors; Zidovudine

2000
Prenatal zidovudine use and congenital anomalies in a medicaid population.
    Journal of acquired immune deficiency syndromes (1999), 2000, Jul-01, Volume: 24, Issue:3

    Topics: Abnormalities, Drug-Induced; Adult; Anti-HIV Agents; Cardiovascular Abnormalities; Central Nervous System; Digestive System Abnormalities; Female; HIV Infections; Humans; Infant, Newborn; Male; Medicaid; Musculoskeletal Abnormalities; New York; New York City; Parity; Pregnancy; Prenatal Exposure Delayed Effects; Prevalence; Registries; Retrospective Studies; United States; Zidovudine

2000
Mitochondrial and peroxisomal dysfunction following perinatal exposure to antiretroviral drugs.
    AIDS (London, England), 2000, Jul-28, Volume: 14, Issue:11

    Topics: Anti-HIV Agents; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Male; Mitochondria; Perinatal Care; Peroxisomes; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Zidovudine

2000
Absence of cardiac toxicity of zidovudine in infants. Pediatric Pulmonary and Cardiac Complications of Vertically Transmitted HIV Infection Study Group.
    The New England journal of medicine, 2000, Sep-14, Volume: 343, Issue:11

    Topics: Anti-HIV Agents; Child, Preschool; Female; Heart Ventricles; HIV Infections; Humans; Infant; Infant, Newborn; Longitudinal Studies; Male; Mitochondria, Heart; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Prenatal Exposure Delayed Effects; Ventricular Function; Ventricular Function, Left; Zidovudine

2000
Perinatal exposure to zidovudine--benefits and risks.
    The New England journal of medicine, 2000, Sep-14, Volume: 343, Issue:11

    Topics: Anti-HIV Agents; Female; Heart Ventricles; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Longitudinal Studies; Mitochondria, Heart; Pregnancy; Pregnancy Complications, Infectious; Pregnant Women; Prenatal Care; Prenatal Exposure Delayed Effects; Risk Assessment; Ventricular Function, Left; Zidovudine

2000
Acute lymphoblastic leukaemia in an infant exposed to zidovudine in utero and early infancy.
    AIDS (London, England), 2000, Oct-20, Volume: 14, Issue:15

    Topics: Female; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine

2000
Drug safety during pregnancy and in infants. Lack of mortality related to mitochondrial dysfunction among perinatally HIV-exposed children in pediatric HIV surveillance.
    Annals of the New York Academy of Sciences, 2000, Volume: 918

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cause of Death; Child; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Infant, Newborn; Los Angeles; Mitochondrial Myopathies; New York City; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; United States; Zidovudine

2000
A comparison of genetic mitochondrial disease and nucleoside analogue toxicity. Does fetal nucleoside toxicity underlie reports of mitochondrial disease in infants born to women treated for HIV infection?
    Annals of the New York Academy of Sciences, 2000, Volume: 918

    Topics: Anti-HIV Agents; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Mitochondria; Mitochondrial Myopathies; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Zidovudine

2000
Antiretroviral pharmacology in pregnant women and their newborns.
    Annals of the New York Academy of Sciences, 2000, Volume: 918

    Topics: Administration, Oral; Anti-HIV Agents; Delivery, Obstetric; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Labor, Obstetric; Maternal-Fetal Exchange; Nevirapine; Placenta; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Protease Inhibitors; Reverse Transcriptase Inhibitors; Zidovudine

2000
Effects of prenatal AZT+3TC treatment on open field behavior and responsiveness to scopolamine in adult mice.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 67, Issue:3

    Topics: Animals; Behavior, Animal; Female; Lamivudine; Male; Mice; Muscarinic Antagonists; Pregnancy; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Scopolamine; Zidovudine

2000
Prenatal exposure to anti-HIV drugs: neurobehavioral effects of zidovudine (AZT) + lamivudine (3TC) treatment in mice.
    Teratology, 2001, Volume: 63, Issue:1

    Topics: Animals; Anti-HIV Agents; Avoidance Learning; Body Weight; Female; Gestational Age; Hand Strength; Homing Behavior; Lamivudine; Male; Mice; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Reflex; Social Behavior; Zidovudine

2001
Absence of cardiac toxicity of zidovudine in infants.
    The New England journal of medicine, 2001, Feb-08, Volume: 344, Issue:6

    Topics: Adult; Animals; Anti-HIV Agents; Cardiomyopathies; Child; Female; Heart Ventricles; HIV Infections; Humans; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Prenatal Exposure Delayed Effects; Zidovudine

2001
Prenatal AZT or 3TC and mouse development of locomotor activity and hot-plate responding upon administration of the GABA(A) receptor agonist muscimol.
    Psychopharmacology, 2001, Volume: 153, Issue:4

    Topics: Animals; Anti-HIV Agents; Female; GABA Agonists; GABA-A Receptor Agonists; Habituation, Psychophysiologic; Lamivudine; Male; Mice; Motor Activity; Muscimol; Pain Measurement; Pregnancy; Prenatal Exposure Delayed Effects; Reaction Time; Time Factors; Zidovudine

2001
NIH reaffirms support for perinatal AZT despite cancer findings. National Institutes of Health.
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1997

    Topics: Animals; Anti-HIV Agents; Female; Health Policy; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Mice; Neoplasms; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Zidovudine

1997
The triple whammy & pregnancy.
    Research initiative, treatment action : RITA, 1998, Volume: 4, Issue:3

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Viral Load; Zidovudine

1998
Neurological disorders after zidovudine exposure in utero.
    Prescrire international, 1999, Volume: 8, Issue:44

    Topics: Female; France; HIV Infections; Humans; Infant, Newborn; Lamivudine; Mitochondria; Neurotoxicity Syndromes; Pregnancy; Prenatal Exposure Delayed Effects; Retrospective Studies; United States; Zidovudine

1999
Postnatal zidovudine in prevention of vertical HIV-1 transmission in a service setting.
    Journal of tropical pediatrics, 2001, Volume: 47, Issue:4

    Topics: Anti-HIV Agents; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Pregnancy; Prenatal Exposure Delayed Effects; Retrospective Studies; Risk Factors; South Africa; Zidovudine

2001
Retroviruses and mouse embryos: a rapid model for neurovirulence and transplacental antiviral therapy.
    Science (New York, N.Y.), 1987, Jun-26, Volume: 236, Issue:4809

    Topics: Animals; Animals, Newborn; Antiviral Agents; Central Nervous System Diseases; Female; Fetal Diseases; Gestational Age; Maternal-Fetal Exchange; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Retroviridae; Thymidine; Tumor Virus Infections; Virulence; Zidovudine

1987