zidovudine has been researched along with Delayed Effects, Prenatal Exposure in 78 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (1.28) | 18.7374 |
1990's | 19 (24.36) | 18.2507 |
2000's | 40 (51.28) | 29.6817 |
2010's | 18 (23.08) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Blanche, S; Clavel, J; Dollfus, C; Faye, A; Goujon, S; Hleyhel, M; Mandelbrot, L; Sibiude, J; Tubiana, R; Warszawski, J | 1 |
Dugange, F; Harms, G; Hauser, A; Kirschner, W; Kunz, A; Lau, I; Sewangi, J; Theuring, S; Ziske, J | 1 |
André-Schmutz, I; Azria, E; Benachi, A; Blanche, S; Bouallag, N; Cagnard, N; Cavazzana, M; Cocchiarella, F; Cordier, AG; Dal-Cortivo, L; Kaltenbach, S; Le Chenadec, J; Leschi, C; Luce, S; Mandelbrot, L; Mavilio, F; Radford-Weiss, I; Recchia, A; Reimann, C; Revy, P; Six, E; Ternaux, B | 1 |
Drzazga, Z; Kaszuba, M; Maciejewska, K | 1 |
Albano, J; Gee, C; Koram, N; Tilson, H; Vannappagari, V | 1 |
Albano, JD; Koram, N; Napier, MD; Scheuerle, AE; Tilson, H; Vannappagari, V | 1 |
Divi, RL; Gibbons, AT; Liu, Y; Poirier, MC; Shide, ED; Shim Park, E; Woodward, RA | 1 |
Cardellach, F; Catalán-García, M; Coll, O; García-Otero, L; Garrabou, G; Gratacós, E; Guitart-Mampel, M; Hernández, S; López, M; Milisenda, J; Miró, Ò; Morén, C | 1 |
Bae, WH; Essex, M; Lockman, S; Onyait, K; Shapiro, RL; Smeaton, LM; Thior, I; Wester, C | 1 |
Hong, HH; Koujitani, T; Lahousse, SA; Sills, RC; Ton, TV; Wakamatsu, N | 1 |
Aldrovandi, GM; Chu, C; Foca, M; Ha, BF; Li, D; McIntosh, K; Meyer, WA; Moye, J; Rich, KC; Shearer, WT; Thompson, B; Walter, J | 1 |
Carter, MM; March, TH; McCash, CL; Poirier, MC; Seilkop, SK; Torres, SM; Walker, DM; Walker, VE | 1 |
Campen, MJ; Carter, MM; Chu, Y; Divi, RL; Einem, TL; Kang, H; McCash, CL; Poirier, MC; Seilkop, SK; Torres, SM; Walker, DM; Walker, VE | 1 |
Borum, PR; Brogly, SB; Chernoff, MC; Crain, MJ; Ford-Chatterton, HM; Malee, KM; Meyer, WA; Mitchell, WG; Moye, JH; Oleske, JM; Seage Iii, GR; Van Dyke, RB | 1 |
Baroncelli, S; Floridia, M; Genovese, O; Pinnetti, C; Tamburrini, E | 1 |
Dryden-Peterson, S; Essex, M; Hughes, MD; Lockman, S; Makhema, J; Moffat, C; Moyo, S; Ogwu, A; Powis, K; Shapiro, RL | 1 |
Bhattacharyya, A; Pandey, BL; Rai, AK; Rajlakshmi, C; Roy, JK | 1 |
Colan, SD; Mittleman, MA; Oleske, JM; Patel, K; Seage, GR; Van Dyke, RB | 1 |
Aloe, L; Calamandrei, G; Puopolo, M; Valanzano, A | 1 |
Alleva, E; Capone, F; Cirulli, F; Venerosi, A | 1 |
Ayers, L | 1 |
Al-Harthi, L; Blattner, WA; Charurat, M; Divi, RL; Landay, AL; Nguyen, V; Olivero, OA; Poirier, MC; Walker, B; Walker, VE | 1 |
Bishop, JB; Tice, RR; Witt, KL; Wolfe, GW | 2 |
Abrams, EJ; Adams, ME; Divi, RL; Nagashima, K; Nesel, CJ; O'Neill, JP; Poirier, MC; Seilkop, SK; Wade, NA; Walker, VE | 1 |
Abduch, R; Duarte, G; El Beitune, P; Figueiró-Filho, EA; Marcolin, AC; Quintana, SM | 1 |
Duarte, G; El Beitune, P; Figueiró-Filho, EA; Foss, MC; Montenegro, RM; Nogueira, AA; Quintana, SM | 1 |
Ball, W; Barret, B; Blanche, S; Brunelle, F; Lachassine, E; Mayaux, MJ; Pautard, B; Raybaud, C; Tardieu, M | 1 |
Ashley, N; Clark, A; Field, P; Harris, D; Hartley, M; Morten, K; Poulton, J; Williams, KA | 1 |
Chiapello, N; Gabiano, C; Spada, M; Tovo, PA; Zeviani, M | 1 |
Bhakeecheep, S; Briand, N; Hansudewechakul, R; Hongsiriwon, S; Ithisukanan, J; Karnchanamayul, V; Lallemant, M; Le Coeur, S; McIntosh, K; Ngampiyasakul, C; Traisathit, P | 1 |
Venhoff, N; Walker, UA | 1 |
Benhammou, V; Blanche, S; Rustin, P; Tardieu, M; Warszawski, J | 1 |
Dabis, F; Elenga, N; Fassinou, P; Msellati, P; Viho, I | 1 |
Blanche, S | 1 |
Abzug, MJ; Brady, M; Brogly, SB; Crain, MJ; Hughes, MD; Jean-Philippe, P; Mofenson, LM; Oleske, J; Seage, GR; Van Dyke, R; Ylitalo, N | 1 |
Blanche, S; Cibert, C; Costagliola, D; Firtion, G; Floch, C; Nigon, F; Parat, S; Senda, S; Viegas-Péquignot, E | 1 |
Gibb, DM; Newell, ML | 1 |
Cobb, JR; Etemadi, AA; Jones, TM; Lemon, T; Majekodunmi, MJ; Urso, P; Wirsiy, YG | 1 |
Andrews, E; Eldridge, R; White, A | 1 |
Ayers, KM; Reynolds, DJ; Torrey, CE | 1 |
Csete, B; Faludi, B; Hajnal, A; Jandó, G; Lénád, L; Petykó, Z; Sümegi, B | 1 |
Abkowitz, JL; Conrad, SH; Ha, JC; Mottet, NK; Nosbisch, C; Robinette, R; Ruppenthal, GC; Sackett, GP; Unadkat, JD | 1 |
Nersesyan, AK | 1 |
Anderson, LM; Diwan, BA; Haines, DC; Logsdon, D; Olivero, OA; Poirier, MC; Rice, JM; Yuspa, SH; Zhang, Z | 1 |
Brady, M; Culnane, M; Cunningham, B; Diaz, C; Flynn, PM; Fowler, M; Gortmaker, SL; Jimenez, E; Lee, SS; McSherry, G; Mofenson, L; Moore, EC; O'Donnell, K; Oleske, J; Scott, G; Shapiro, DE | 1 |
Alleva, E; Branchi, I; Calamandrei, G; Venerosi, A | 1 |
Agostoni, C; D'Auria, E; Riva, E; Torcoletti, M; Zuccotti, GV | 1 |
Alleva, E; Branchi, I; Calamandrei, G; Rondinini, C; Venerosi, A | 1 |
Barret, B; Blanche, S; Ciraru-Vigneron, N; Delfraissy, JF; Desguerre, I; Firtion, G; Lacroix, C; Mandelbrot, L; Mayaux, MJ; Rötig, A; Rouzioux, C; Rustin, P; Slama, A; Tardieu, M | 1 |
Fowler, MG | 1 |
Diwan, BA; Olivero, OA; Poirier, MC | 1 |
Baker, R; Chougnet, C; Kovacs, A; Liewehr, DJ; Luban, NL; Mueller, BU; Shearer, GM; Steinberg, SM; Thomas, EK | 1 |
Ewings, EL; Gerschenson, M; Harbaugh, JW; Harbaugh, SW; Nagashima, K; Poirier, MC; Skopets, B; St Claire, MC | 1 |
de Souza, RS; Gómez-Marín, O; Guasti, S; Mitchell, CD; O'Sullivan, MJ; Oliveira, RH; Scott, GB | 1 |
Anderson, CE; Cocroft, J; Hauck, WW; Newschaffer, CJ; Turner, BJ | 1 |
Belohradsky, BH; Rolinski, B; Stojanov, S; Wintergerst, U | 1 |
Bricker, JT; Colan, SD; Easley, KA; Kaplan, S; Lai, WW; Lipshultz, SE; McIntosh, K; Moodie, DS; Orav, EJ; Sopko, G; Starc, TJ | 1 |
Mofenson, LM | 1 |
Moschovi, M; Papaevangelou, V; Theodoridou, M; Tzortzatou-Stathopoulou, F | 1 |
Fleming, P; Gordon, L; Lindegren, ML; Rhodes, P | 1 |
Haas, RH | 1 |
Mirochnick, M | 1 |
Alleva, E; Calamandrei, G; Valanzano, A; Venerosi, A | 2 |
Lewis, W | 1 |
Alleva, E; Ricceri, L; Sorace, A; Valanzano, A; Venerosi, A | 1 |
Highleyman, L | 1 |
Eriksen, N | 1 |
Cotton, MF; Pieper, CH; Rabie, H; Robson, B | 1 |
Jaenisch, R; Ruprecht, RM; Sharpe, AH | 1 |
4 review(s) available for zidovudine and Delayed Effects, Prenatal Exposure
Article | Year |
---|---|
Antiretroviral therapy during pregnancy and early neonatal life: consequences for HIV-exposed, uninfected children.
Topics: Anti-HIV Agents; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Zidovudine | 2004 |
Mitochondrial disease in the offspring as a result of antiretroviral therapy.
Topics: Animals; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Female; HIV Infections; Humans; Infant, Newborn; Mitochondrial Diseases; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Zidovudine | 2006 |
A risk-benefit assessment of zidovudine in the prevention of perinatal HIV transmission.
Topics: Acquired Immunodeficiency Syndrome; Animals; Drug Resistance, Microbial; Female; Guidelines as Topic; HIV; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Randomized Controlled Trials as Topic; Risk Assessment; Zidovudine | 1995 |
Follow-up of children exposed to perinatal antiretrovirals.
Topics: Anemia; Anti-HIV Agents; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Pregnancy; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Zidovudine | 2000 |
6 trial(s) available for zidovudine and Delayed Effects, Prenatal Exposure
Article | Year |
---|---|
Hematologic and hepatic toxicities associated with antenatal and postnatal exposure to maternal highly active antiretroviral therapy among infants.
Topics: Alanine Transaminase; Anti-HIV Agents; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Aspartate Aminotransferases; Biomarkers; Botswana; Breast Feeding; Cohort Studies; Female; Follow-Up Studies; Hemoglobins; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Neutropenia; Nevirapine; Platelet Count; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Zidovudine | 2008 |
Increased risk of severe infant anemia after exposure to maternal HAART, Botswana.
Topics: Adult; Anemia; Antiretroviral Therapy, Highly Active; Botswana; Breast Feeding; Female; HIV Infections; HIV-1; Humans; Incidence; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Perinatal Care; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Severity of Illness Index; Treatment Outcome; Zidovudine | 2011 |
Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers.
Topics: Adult; Child, Preschool; DNA, Mitochondrial; Female; Fetal Blood; Genetic Markers; HIV Infections; Humans; Infant; Infant, Newborn; Leukocytes, Mononuclear; Pilot Projects; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Ribosomal, 18S; Telomere; Zidovudine | 2003 |
Growth of human immunodeficiency virus-uninfected children exposed to perinatal zidovudine for the prevention of mother-to-child human immunodeficiency virus transmission.
Topics: Anti-HIV Agents; Body Height; Body Mass Index; Body Weight; Female; Growth; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Thailand; Zidovudine | 2006 |
In utero nucleoside reverse transcriptase inhibitor exposure and signs of possible mitochondrial dysfunction in HIV-uninfected children.
Topics: Anti-HIV Agents; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV Reverse Transcriptase; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Maternal-Fetal Exchange; Mitochondrial Diseases; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Sex Factors; Zidovudine | 2007 |
Lack of long-term effects of in utero exposure to zidovudine among uninfected children born to HIV-infected women. Pediatric AIDS Clinical Trials Group Protocol 219/076 Teams.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Child Development; Child, Preschool; Echocardiography; Female; Growth; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Longitudinal Studies; Male; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Prospective Studies; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Vision Tests; Zidovudine | 1999 |
68 other study(ies) available for zidovudine and Delayed Effects, Prenatal Exposure
Article | Year |
---|---|
Risk of cancer in children exposed to antiretroviral nucleoside analogues in utero: The french experience.
Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Didanosine; Female; HIV Infections; Humans; Incidence; Infant; Infant, Newborn; Male; Maternal Exposure; Maternal-Fetal Exchange; Neoplasms; Nucleosides; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Reverse Transcriptase Inhibitors; Risk; Surveys and Questionnaires; Zidovudine | 2019 |
Hematological changes in women and infants exposed to an AZT-containing regimen for prevention of mother-to-child-transmission of HIV in Tanzania.
Topics: Adolescent; Adult; Anti-HIV Agents; Blood Cell Count; Drug Therapy, Combination; Female; Hematocrit; Hematologic Diseases; Hematologic Tests; Hemoglobins; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Mothers; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Tanzania; Young Adult; Zidovudine | 2013 |
Genotoxic signature in cord blood cells of newborns exposed in utero to a Zidovudine-based antiretroviral combination.
Topics: Adult; Anti-HIV Agents; Antigens, CD34; Cell Cycle; DNA Repair; Drug Combinations; Female; Fetal Blood; Gene Expression Profiling; Hematopoietic Stem Cells; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Karyotyping; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Stem Cells; Transcriptome; Young Adult; Zidovudine | 2013 |
Toxicology and carcinogenesis of 3´-azido-3´-deoxythymidine (AZT) (CAS No. 30516-87-1) in genetically modified C3B6.129F1-Trp53(tm1Brd) N12 haploinsufficient mice (in utero and postnatal gavage studies).
Topics: Animals; Anti-HIV Agents; Carcinogens; Female; Genes, p53; Haploinsufficiency; Humans; Liver Neoplasms, Experimental; Lymphoma; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine | 2013 |
Toxicology and Carcinogenesis Studies of Mixtures of 3'-Azido-3'-Deoxythymidine (AZT), Lamivudine (3TC), and Nevirapine (NVP) (CAS Nos. 30516-87-1, 134678-17-4, 129618-40-2) in Genetically Modified C3B6.129F1-Trp53(tm1Brd) N12 Haploinsufficient Mice (in u
Topics: Animals; Animals, Genetically Modified; Animals, Newborn; Anti-HIV Agents; Body Weight; Chemistry, Pharmaceutical; Drug Combinations; Female; Haploinsufficiency; Intubation, Gastrointestinal; Lamivudine; Litter Size; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mutagens; Nevirapine; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Reproduction; Reverse Transcriptase Inhibitors; Survival; Zidovudine | 2013 |
The changes in bone organic and inorganic matrix in newborn rats after maternal application of antiretroviral agents: Indinavir and zidovudine.
Topics: Animals; Anti-Retroviral Agents; Bone Density; Calcium; Female; Femur; Humans; Incisor; Indinavir; Mandible; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Skull; Tibia; Trace Elements; Zidovudine | 2015 |
Association between in utero zidovudine exposure and nondefect adverse birth outcomes: analysis of prospectively collected data from the Antiretroviral Pregnancy Registry.
Topics: Abortion, Induced; Abortion, Spontaneous; Adolescent; Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Infant, Low Birth Weight; Live Birth; Middle Aged; Pregnancy; Pregnancy Complications, Infectious; Premature Birth; Prenatal Exposure Delayed Effects; Prevalence; Registries; Risk Factors; Stillbirth; Young Adult; Zidovudine | 2016 |
Prenatal exposure to zidovudine and risk for ventricular septal defects and congenital heart defects: data from the Antiretroviral Pregnancy Registry.
Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Argentina; Brazil; Case-Control Studies; Female; France; Gestational Age; Heart Defects, Congenital; Heart Septal Defects, Ventricular; HIV Infections; Humans; Live Birth; Middle Aged; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Second; Prenatal Exposure Delayed Effects; Prevalence; Prospective Studies; Registries; Risk Factors; South Africa; Uganda; United Kingdom; United States; Young Adult; Zidovudine | 2016 |
Mitochondrial compromise in 3-year old patas monkeys exposed in utero to human-equivalent antiretroviral therapies.
Topics: Animals; Anti-HIV Agents; Bone Marrow Cells; Brain; Dideoxynucleosides; DNA, Mitochondrial; Drug Therapy, Combination; Erythrocebus patas; Female; Gestational Age; Heart; Lamivudine; Mitochondria; Mitochondria, Heart; Oxygen Consumption; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine | 2016 |
Placental Mitochondrial Toxicity, Oxidative Stress, Apoptosis, and Adverse Perinatal Outcomes in HIV Pregnancies Under Antiretroviral Treatment Containing Zidovudine.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Apoptosis; Case-Control Studies; Contraindications; Cross-Sectional Studies; DNA, Mitochondrial; Female; Fetal Blood; HIV Infections; Humans; Infant, Newborn; Infant, Small for Gestational Age; Infectious Disease Transmission, Vertical; Maternal-Fetal Exchange; Oxidative Stress; Placenta; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Spain; Zidovudine | 2017 |
K-ras cancer gene mutations in lung tumors from female Swiss (CD-1) mice exposed transplacentally to 3'-azido-3'-deoxythymidine.
Topics: Animals; Female; Genes, ras; Lung Neoplasms; Male; Maternal Exposure; Mice; Mutation; Pregnancy; Prenatal Exposure Delayed Effects; Sex Factors; Zidovudine | 2008 |
Antiretroviral exposure and lymphocyte mtDNA content among uninfected infants of HIV-1-infected women.
Topics: Anti-HIV Agents; DNA, Mitochondrial; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Longitudinal Studies; Monocytes; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; Prenatal Exposure Delayed Effects; Reference Values; Reverse Transcriptase Inhibitors; Zidovudine | 2009 |
In utero exposure of female CD-1 Mice to AZT and/or 3TC: I. Persistence of microscopic lesions in cardiac tissue.
Topics: Animals; Anti-HIV Agents; DNA, Mitochondrial; Drug Interactions; Echocardiography; Female; Fetus; Heart; Lamivudine; Male; Maternal-Fetal Exchange; Mice; Microscopy, Electron, Transmission; Mitochondria, Heart; Mutation; Myocardium; Organ Size; Oxidative Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Sex Characteristics; Zidovudine | 2010 |
In utero exposure of female CD-1 mice to AZT and/or 3TC: II. Persistence of functional alterations in cardiac tissue.
Topics: Animals; Anti-HIV Agents; DNA, Mitochondrial; Drug Interactions; Drug Therapy, Combination; Echocardiography; Electron Transport Chain Complex Proteins; Electrophoresis, Polyacrylamide Gel; Female; Heart; Lamivudine; Luminescent Measurements; Maternal Exposure; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Microscopy, Electron, Transmission; Mitochondria, Heart; Myocardium; Oxidative Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Time Factors; Zidovudine | 2010 |
Possible mitochondrial dysfunction and its association with antiretroviral therapy use in children perinatally infected with HIV.
Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Cohort Studies; Female; HIV Infections; Humans; Infant, Newborn; Male; Mitochondrial Diseases; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Regression Analysis; Stavudine; United States; Zidovudine | 2010 |
Hematological effects of zidovudine prophylaxis in newborn infants with and without prenatal exposure to zidovudine.
Topics: Anti-HIV Agents; Antibiotic Prophylaxis; Female; Hematologic Tests; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Treatment Outcome; Zidovudine | 2011 |
An unusual phenotypic and genotypic expression in F2 generation following one stage zidovudine exposure during pregnancy and lactation- an experiment in mice.
Topics: Abdominal Fat; Animals; Anti-HIV Agents; Bone Marrow Cells; Chromosome Aberrations; Female; Genes, Recessive; Lactation; Liver; Male; Maternal-Fetal Exchange; Mice; Mutagens; Mutation; Phenotype; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine | 2012 |
The impact of HAART on cardiomyopathy among children and adolescents perinatally infected with HIV-1.
Topics: Adolescent; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cardiomyopathies; Cardiotonic Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Cohort Studies; Digoxin; Female; Follow-Up Studies; HIV Seropositivity; Humans; Infant; Infectious Disease Transmission, Vertical; Male; Pregnancy; Prenatal Exposure Delayed Effects; Proportional Hazards Models; Prospective Studies; Treatment Outcome; United States; Zalcitabine; Zidovudine | 2012 |
Toxicology and carcinogenesis studies of mixtures of 3'-azido-3'-deoxythymidine (AZT), lamivudine (3TC), nevirapine (NVP), and nelfinavir mesylate (NFV) (Cas Nos. 30516-87-1, 134678-17-4, 129618-40-2, 159989-65-8) in B6C3F1 Mice (transplacental exposure s
Topics: Administration, Oral; Animals; Anti-Retroviral Agents; DNA; Drug Therapy, Combination; Escherichia coli; Female; Lamivudine; Longevity; Male; Maternal Exposure; Mice; Mice, Inbred Strains; Nelfinavir; Nevirapine; Pregnancy; Prenatal Exposure Delayed Effects; Salmonella typhimurium; Skin Neoplasms; Zidovudine | 2013 |
Developmental exposure to the antiretroviral drug zidovudine increases brain levels of brain-derived neurotrophic factor in mice.
Topics: Age Factors; Animals; Animals, Newborn; Antimetabolites; Brain; Brain-Derived Neurotrophic Factor; Female; Male; Mice; Nerve Growth Factor; Pregnancy; Prenatal Exposure Delayed Effects; Sex Factors; Time Factors; Zidovudine | 2002 |
Prolonged perinatal AZT administration and early maternal separation: effects on social and emotional behaviour of periadolescent mice.
Topics: Animals; Animals, Newborn; Corticosterone; Emotions; Female; Male; Maternal Exposure; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Social Behavior; Zidovudine | 2003 |
Is mama a criminal? An analysis of potential criminal liability of HIV-infected pregnant women in the context of mandated drug therapy.
Topics: Child; Child Advocacy; Coercion; Criminal Law; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Liability, Legal; Mandatory Testing; Patient Compliance; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Privacy; Treatment Refusal; United States; Zidovudine | 2002 |
Genetic damage detected in CD-1 mouse pups exposed perinatally to 3'-azido-3'-deoxythymidine and dideoxyinosine via maternal dosing, nursing, and direct gavage.
Topics: Administration, Oral; Animals; Anti-HIV Agents; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythrocytes; Female; Lactation; Male; Mice; Mice, Inbred Strains; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Pregnancy; Prenatal Exposure Delayed Effects; Time Factors; Zidovudine | 2004 |
Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; DNA, Mitochondrial; Drug Combinations; Female; Fetal Blood; HIV Infections; HIV-1; Humans; Infant, Newborn; Lamivudine; Maternal-Fetal Exchange; Microscopy, Electron; Mitochondria; Pilot Projects; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Umbilical Cord; Zidovudine | 2004 |
Genetic damage detected in CD-1 mouse pups exposed perinatally to 3'-azido-3'-deoxythymidine or dideoxyinosine via maternal dosing, nursing, and direct gavage: II. Effects of the individual agents compared to combination treatment.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anti-HIV Agents; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythrocytes; Female; Male; Mice; Mice, Inbred Strains; Micronuclei, Chromosome-Defective; Micronucleus Tests; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine | 2004 |
Effect of maternal use of antiretroviral agents on serum insulin levels of the newborn infant.
Topics: Adolescent; Adult; Anti-HIV Agents; Blood Glucose; Cohort Studies; Female; Fetal Blood; Humans; Infant, Newborn; Insulin; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Zidovudine | 2005 |
Cerebral MR imaging in uninfected children born to HIV-seropositive mothers and perinatally exposed to zidovudine.
Topics: Anti-HIV Agents; Brain; Child, Preschool; Female; HIV Seropositivity; Humans; Infant; Magnetic Resonance Imaging; Male; Mitochondrial Encephalomyopathies; Mothers; Pilot Projects; Pregnancy; Prenatal Exposure Delayed Effects; Retrospective Studies; Zidovudine | 2005 |
Fetal and neonatal exposure to AZT and low-protein diet affects glucose homeostasis: a model with implications for AIDS prevention.
Topics: Acquired Immunodeficiency Syndrome; Animals; Birth Weight; Blood Glucose; Diabetes Mellitus; Diet, Protein-Restricted; DNA, Mitochondrial; Female; Fetal Development; Homeostasis; Insulin; Islets of Langerhans; Litter Size; Liver; Mice; Mice, Inbred C57BL; Models, Animal; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine | 2005 |
Zidovudine administration during pregnancy and mitochondrial disease in the offspring.
Topics: Anti-HIV Agents; Chemoprevention; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Mitochondrial Diseases; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Zidovudine | 2005 |
Mitochondrial dysfunction following perinatal exposure to nucleoside analogues.
Topics: Anti-HIV Agents; Child; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Lamivudine; Mitochondrial Diseases; Nervous System Diseases; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Zidovudine | 2006 |
[Zidovudine-associated mitochondriopathy: three possible observations in Abidjan, Côte d'Ivoire].
Topics: Adult; Anemia, Hypochromic; Anti-HIV Agents; Cohort Studies; Comorbidity; Cote d'Ivoire; Epilepsy, Generalized; Failure to Thrive; Female; Fetus; Growth Disorders; HIV Infections; Humans; Infant; Male; Mitochondria; Muscle Hypotonia; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Protein-Energy Malnutrition; Psychomotor Disorders; Randomized Controlled Trials as Topic; Zidovudine | 2004 |
[Possible long-term effect of in utero antiretroviral exposure?].
Topics: Anti-HIV Agents; Anti-Retroviral Agents; Child; DNA, Mitochondrial; Female; Fetus; Humans; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine | 2007 |
Altered heterochromatin organization after perinatal exposure to zidovudine.
Topics: Adolescent; Anti-HIV Agents; Case-Control Studies; Cells, Cultured; Child; Child, Preschool; Chromatin Assembly and Disassembly; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 16; Cohort Studies; DNA Methylation; Female; Heterochromatin; HIV Infections; HIV-1; Humans; In Situ Hybridization, Fluorescence; Infant; Infant, Newborn; Leukocytes; Pregnancy; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Time Factors; Zidovudine | 2007 |
Recommendations of the U.S. Public Health Service Task Force on the use of zidovudine to reduce perinatal transmission of human immunodeficiency virus.
Topics: Adult; CD4-Positive T-Lymphocytes; Drug Administration Schedule; Female; Fetal Monitoring; Gestational Age; Hematologic Tests; HIV Infections; Humans; Infant; Infant, Newborn; Leukocyte Count; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Randomized Controlled Trials as Topic; Zidovudine | 1994 |
Birth outcomes following zidovudine therapy in pregnant women.
Topics: Abnormalities, Drug-Induced; Female; HIV Infections; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Registries; Zidovudine | 1994 |
From the Centers for Disease Control and Prevention. Birth outcomes following zidovudine therapy in pregnant women.
Topics: Abnormalities, Drug-Induced; Female; HIV Infections; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Registries; Zidovudine | 1994 |
Zidovudine as an immunomodulatory agent.
Topics: Administration, Oral; Animals; Animals, Newborn; Antibody Formation; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Drug Evaluation; Female; Hemolytic Plaque Technique; Immunologic Deficiency Syndromes; Immunosuppressive Agents; Injections, Intravenous; Lymphocyte Culture Test, Mixed; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; T-Lymphocytes; Zidovudine | 1995 |
Birth outcomes following zidovudine exposure in pregnant women: the Antiretroviral Pregnancy Registry.
Topics: Abnormalities, Drug-Induced; Anti-HIV Agents; Female; HIV Infections; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Registries; Teratogens; Zidovudine | 1997 |
A transplacental carcinogenicity bioassay in CD-1 mice with zidovudine.
Topics: Animals; Anti-HIV Agents; Body Weight; Carcinogenicity Tests; Carcinogens; Carcinoma, Squamous Cell; Female; Male; Mice; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; Radioimmunoassay; Vaginal Neoplasms; Zidovudine | 1997 |
Learning disturbances in offsprings of zidovudine (AZT) treated rats.
Topics: Animals; Anti-HIV Agents; Behavior, Animal; Female; Learning Disabilities; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Zidovudine | 1997 |
Fetal, infant, and maternal toxicity of zidovudine (azidothymidine) administered throughout pregnancy in Macaca nemestrina.
Topics: Anemia; Animals; Animals, Newborn; Anti-HIV Agents; Area Under Curve; Bone Marrow; Erythrocyte Indices; Erythropoietin; Female; Fetal Death; Fetal Resorption; Fetus; Hematocrit; Hemoglobins; Leukocyte Count; Macaca nemestrina; Organ Size; Placenta; Platelet Count; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Random Allocation; Zidovudine | 1998 |
Re: Transplacental effects of 3'-azido-2',3'-dideoxythymidine (AZT): tumorigenicity in mice and genotoxicity in mice and monkeys.
Topics: Animals; Anti-HIV Agents; Antimetabolites, Antineoplastic; Female; Male; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine | 1998 |
Skin tumorigenesis and Ki-ras and Ha-ras mutations in tumors from adult mice exposed in utero to 3'-azido-2',3'-dideoxythymidine.
Topics: Animals; Anti-HIV Agents; Female; Genes, ras; Liver Neoplasms; Lung Neoplasms; Mice; Mutation; Pregnancy; Prenatal Exposure Delayed Effects; Skin Neoplasms; Zidovudine | 1998 |
Effects of prenatal zidovudine treatment on learning and memory capacities of preweanling and young adult mice.
Topics: Animals; Anti-HIV Agents; Avoidance Learning; Body Weight; Chromatography, High Pressure Liquid; Drinking; Eating; Female; Learning; Male; Maze Learning; Memory; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Reproduction; Zidovudine | 1999 |
Infant growth after in utero exposure to zidovudine.
Topics: Anti-HIV Agents; Female; Growth; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Male; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Zidovudine | 1999 |
Long-term effects of prenatal 3'-azido-3'-deoxythymidine (AZT) exposure on intermale aggressive behaviour of mice.
Topics: Aggression; Animals; Anti-HIV Agents; Female; Male; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine | 1999 |
Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analogues.
Topics: Acidosis, Lactic; Anti-HIV Agents; Child, Preschool; DNA, Mitochondrial; Female; France; HIV Infections; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Maternal-Fetal Exchange; Mitochondrial Encephalomyopathies; Pregnancy; Prenatal Exposure Delayed Effects; Reference Values; Retrospective Studies; Zidovudine | 1999 |
Absence of structural or functional alterations in male and female reproductive organs of F1 and F2 generations derived from female mice exposed to 3'-azido-3'-deoxythymidine during pregnancy.
Topics: Abnormalities, Drug-Induced; Animals; Anti-HIV Agents; Female; Fertility; Genitalia; Male; Mice; Organ Size; Pregnancy; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Zidovudine | 2000 |
Influence of human immunodeficiency virus-infected maternal environment on development of infant interleukin-12 production.
Topics: Adult; Anti-HIV Agents; Cells, Cultured; Child, Preschool; Cytokines; Female; Fetal Blood; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Interleukin-10; Interleukin-12; Lymphocytes; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Regression Analysis; Tumor Necrosis Factor-alpha; Zidovudine | 2000 |
Genotoxic and functional consequences of transplacental zidovudine exposure in fetal monkey brain mitochondria.
Topics: Animals; Animals, Newborn; Brain; Cerebellum; DNA, Mitochondrial; Electron Transport Complex II; Erythrocebus patas; Female; Humans; Maternal-Fetal Exchange; Mitochondria; Multienzyme Complexes; Mutagens; NADH Dehydrogenase; Oxidative Phosphorylation; Oxidoreductases; Pregnancy; Prenatal Exposure Delayed Effects; Succinate Dehydrogenase; Zidovudine | 2000 |
Effect of prenatal zidovudine on disease progression in perinatally HIV-1-infected infants.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Disease Progression; Female; Gestational Age; HIV Infections; HIV Seropositivity; HIV-1; Humans; Infant; Infant, Newborn; Infant, Premature; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Retrospective Studies; Risk Factors; Zidovudine | 2000 |
Prenatal zidovudine use and congenital anomalies in a medicaid population.
Topics: Abnormalities, Drug-Induced; Adult; Anti-HIV Agents; Cardiovascular Abnormalities; Central Nervous System; Digestive System Abnormalities; Female; HIV Infections; Humans; Infant, Newborn; Male; Medicaid; Musculoskeletal Abnormalities; New York; New York City; Parity; Pregnancy; Prenatal Exposure Delayed Effects; Prevalence; Registries; Retrospective Studies; United States; Zidovudine | 2000 |
Mitochondrial and peroxisomal dysfunction following perinatal exposure to antiretroviral drugs.
Topics: Anti-HIV Agents; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Male; Mitochondria; Perinatal Care; Peroxisomes; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Zidovudine | 2000 |
Absence of cardiac toxicity of zidovudine in infants. Pediatric Pulmonary and Cardiac Complications of Vertically Transmitted HIV Infection Study Group.
Topics: Anti-HIV Agents; Child, Preschool; Female; Heart Ventricles; HIV Infections; Humans; Infant; Infant, Newborn; Longitudinal Studies; Male; Mitochondria, Heart; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Prenatal Exposure Delayed Effects; Ventricular Function; Ventricular Function, Left; Zidovudine | 2000 |
Perinatal exposure to zidovudine--benefits and risks.
Topics: Anti-HIV Agents; Female; Heart Ventricles; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Longitudinal Studies; Mitochondria, Heart; Pregnancy; Pregnancy Complications, Infectious; Pregnant Women; Prenatal Care; Prenatal Exposure Delayed Effects; Risk Assessment; Ventricular Function, Left; Zidovudine | 2000 |
Acute lymphoblastic leukaemia in an infant exposed to zidovudine in utero and early infancy.
Topics: Female; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine | 2000 |
Drug safety during pregnancy and in infants. Lack of mortality related to mitochondrial dysfunction among perinatally HIV-exposed children in pediatric HIV surveillance.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cause of Death; Child; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Infant, Newborn; Los Angeles; Mitochondrial Myopathies; New York City; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; United States; Zidovudine | 2000 |
A comparison of genetic mitochondrial disease and nucleoside analogue toxicity. Does fetal nucleoside toxicity underlie reports of mitochondrial disease in infants born to women treated for HIV infection?
Topics: Anti-HIV Agents; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Mitochondria; Mitochondrial Myopathies; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Zidovudine | 2000 |
Antiretroviral pharmacology in pregnant women and their newborns.
Topics: Administration, Oral; Anti-HIV Agents; Delivery, Obstetric; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Labor, Obstetric; Maternal-Fetal Exchange; Nevirapine; Placenta; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Protease Inhibitors; Reverse Transcriptase Inhibitors; Zidovudine | 2000 |
Effects of prenatal AZT+3TC treatment on open field behavior and responsiveness to scopolamine in adult mice.
Topics: Animals; Behavior, Animal; Female; Lamivudine; Male; Mice; Muscarinic Antagonists; Pregnancy; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Scopolamine; Zidovudine | 2000 |
Prenatal exposure to anti-HIV drugs: neurobehavioral effects of zidovudine (AZT) + lamivudine (3TC) treatment in mice.
Topics: Animals; Anti-HIV Agents; Avoidance Learning; Body Weight; Female; Gestational Age; Hand Strength; Homing Behavior; Lamivudine; Male; Mice; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Reflex; Social Behavior; Zidovudine | 2001 |
Absence of cardiac toxicity of zidovudine in infants.
Topics: Adult; Animals; Anti-HIV Agents; Cardiomyopathies; Child; Female; Heart Ventricles; HIV Infections; Humans; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Prenatal Exposure Delayed Effects; Zidovudine | 2001 |
Prenatal AZT or 3TC and mouse development of locomotor activity and hot-plate responding upon administration of the GABA(A) receptor agonist muscimol.
Topics: Animals; Anti-HIV Agents; Female; GABA Agonists; GABA-A Receptor Agonists; Habituation, Psychophysiologic; Lamivudine; Male; Mice; Motor Activity; Muscimol; Pain Measurement; Pregnancy; Prenatal Exposure Delayed Effects; Reaction Time; Time Factors; Zidovudine | 2001 |
NIH reaffirms support for perinatal AZT despite cancer findings. National Institutes of Health.
Topics: Animals; Anti-HIV Agents; Female; Health Policy; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Mice; Neoplasms; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Zidovudine | 1997 |
The triple whammy & pregnancy.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Viral Load; Zidovudine | 1998 |
Neurological disorders after zidovudine exposure in utero.
Topics: Female; France; HIV Infections; Humans; Infant, Newborn; Lamivudine; Mitochondria; Neurotoxicity Syndromes; Pregnancy; Prenatal Exposure Delayed Effects; Retrospective Studies; United States; Zidovudine | 1999 |
Postnatal zidovudine in prevention of vertical HIV-1 transmission in a service setting.
Topics: Anti-HIV Agents; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Pregnancy; Prenatal Exposure Delayed Effects; Retrospective Studies; Risk Factors; South Africa; Zidovudine | 2001 |
Retroviruses and mouse embryos: a rapid model for neurovirulence and transplacental antiviral therapy.
Topics: Animals; Animals, Newborn; Antiviral Agents; Central Nervous System Diseases; Female; Fetal Diseases; Gestational Age; Maternal-Fetal Exchange; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Retroviridae; Thymidine; Tumor Virus Infections; Virulence; Zidovudine | 1987 |