zidovudine has been researched along with Chromosome-Defective Micronuclei in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carneiro, CC; Carvalho, CJ; Carvalho, WF; Chen-Chen, L; Cunha, KS; Lima, DC; Moraes Filho, AV; Silva, DM; Vale, CR; Vieira, TB | 1 |
| Borojerdi, JP; Braun, HM; Cooch, C; Ming, J; Olivero, OA; Poirier, MC; Semino-Mora, C; Taylor, BJ; Ward, Y; Yu, M | 1 |
| Borojerdi, JP; Braun, HM; Cooch, CC; Keller, E; McKee, E; Ming, J; Olivero, OA; Poirier, MC; Vazquez, IL; Yu, M | 1 |
| Beland, FA; Bishop, ME; Dobrovolsky, VN; Hamilton, LP; Heflich, RH; Shaddock, JG; Von Tungeln, LS | 1 |
| Aruna, R; Jagetia, GC | 1 |
| Bishop, JB; Tice, RR; Witt, KL; Wolfe, GW | 2 |
| Beland, FA; Dobrovolsky, VN; Heflich, RH; McGarrity, LJ; Mittelstaedt, RA; Morris, SM; VonTungeln, LS | 1 |
| Das, S; Ming, JM; Olivero, OA; Poirier, MC; Richardson, DL; Vazquez, IL; Weston, A | 1 |
| Dertinger, SD; Tometsko, KR; Torous, DK | 1 |
| Agarwal, RP; Olivero, OA | 1 |
| Nascimbeni, B; Phillips, MD; Shelby, MD; Tice, RR | 1 |
12 other study(ies) available for zidovudine and Chromosome-Defective Micronuclei
| Article | Year |
|---|---|
Genotoxic and Cytotoxic Effects of Antiretroviral Combinations in Mice Bone Marrow.
Topics: Animals; Antiretroviral Therapy, Highly Active; Bone Marrow; Comet Assay; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Lamivudine; Mice; Micronuclei, Chromosome-Defective; Tenofovir; Zidovudine | 2016 |
Centrosomal amplification and aneuploidy induced by the antiretroviral drug AZT in hamster and human cells.
Topics: Aneugens; Aneuploidy; Animals; Aurora Kinases; Breast; Cell Cycle; Cell Line; Centrosome; CHO Cells; Cricetinae; Cricetulus; DNA Adducts; Epithelial Cells; Humans; Micronuclei, Chromosome-Defective; Microscopy, Electron, Transmission; Protein Serine-Threonine Kinases; Tubulin; Zidovudine | 2009 |
Long-term AZT exposure alters the metabolic capacity of cultured human lymphoblastoid cells.
Topics: Anti-HIV Agents; Cell Cycle; Cell Line, Tumor; Cell Survival; DNA; DNA Adducts; Down-Regulation; Drug Resistance, Neoplasm; Humans; Micronuclei, Chromosome-Defective; Micronucleus Tests; Phosphorylation; T-Lymphocytes; Thymidine; Thymidine Kinase; Zidovudine | 2010 |
Frequency of Tk and Hprt lymphocyte mutants and bone marrow micronuclei in B6C3F(1)/Tk+/- mice treated neonatally with zidovudine and lamivudine.
Topics: Animals; Anti-HIV Agents; Bone Marrow; Bromodeoxyuridine; Drug Interactions; Drug Resistance, Neoplasm; Erythrocytes; Female; Gene Frequency; Hypoxanthine Phosphoribosyltransferase; Lamivudine; Loss of Heterozygosity; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Micronuclei, Chromosome-Defective; Mutation; Thymidine Kinase; Zidovudine | 2002 |
Correlation of micronuclei-induction with the cell survival in HeLa cells treated with a base analogue, azidothymidine (AZT) before exposure to different doses of gamma-radiation.
Topics: Cell Division; Cell Survival; Dose-Response Relationship, Radiation; Gamma Rays; HeLa Cells; Humans; Logistic Models; Micronuclei, Chromosome-Defective; Zidovudine | 2003 |
Genetic damage detected in CD-1 mouse pups exposed perinatally to 3'-azido-3'-deoxythymidine and dideoxyinosine via maternal dosing, nursing, and direct gavage.
Topics: Administration, Oral; Animals; Anti-HIV Agents; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythrocytes; Female; Lactation; Male; Mice; Mice, Inbred Strains; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Pregnancy; Prenatal Exposure Delayed Effects; Time Factors; Zidovudine | 2004 |
Genetic damage detected in CD-1 mouse pups exposed perinatally to 3'-azido-3'-deoxythymidine or dideoxyinosine via maternal dosing, nursing, and direct gavage: II. Effects of the individual agents compared to combination treatment.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anti-HIV Agents; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythrocytes; Female; Male; Mice; Mice, Inbred Strains; Micronuclei, Chromosome-Defective; Micronucleus Tests; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine | 2004 |
Micronucleated erythrocyte frequency in control and azidothymidine-treated Tk+/+, Tk+/- and Tk-/- mice.
Topics: Animals; Erythrocytes; Flow Cytometry; Genotype; Mice; Micronuclei, Chromosome-Defective; Thymidine Kinase; Zidovudine | 2005 |
Human inter-individual variability in metabolism and genotoxic response to zidovudine.
Topics: Apoptosis; Bleomycin; Blotting, Western; Cell Cycle; Cell Line; Cell Survival; Cells, Cultured; DNA; Epithelial Cells; Flow Cytometry; Humans; Interphase; Mammary Glands, Human; Micronuclei, Chromosome-Defective; Radioimmunoassay; Reverse Transcriptase Inhibitors; Thymidine Kinase; Time Factors; Zidovudine | 2008 |
Induction of micronuclei by low doses of azidothymidine (AZT).
Topics: Animals; Antiviral Agents; Female; Flow Cytometry; Male; Mice; Mice, Inbred BALB C; Micronuclei, Chromosome-Defective; Zidovudine | 1996 |
Genotoxicity and mitochondrial damage in human lymphocytic cells chronically exposed to 3'-azido-2',3'-dideoxythymidine.
Topics: Anti-HIV Agents; Cell Nucleus; Cells, Cultured; Chromosome Aberrations; DNA Adducts; DNA Damage; DNA, Mitochondrial; Humans; Lactic Acid; Lipid Metabolism; Micronuclei, Chromosome-Defective; Mitochondria; Mutagenicity Tests; Radioimmunoassay; T-Lymphocytes; Zidovudine | 1997 |
Induction of micronuclei in mouse bone marrow cells: an evaluation of nucleoside analogues used in the treatment of AIDS.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Animals; Antiviral Agents; Bone Marrow; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred Strains; Micronuclei, Chromosome-Defective; Micronucleus Tests; Molecular Structure; Mutagenicity Tests; Mutagens; Nucleosides; Zidovudine | 1991 |