zidovudine has been researched along with Aging in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (76.47) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Konishi, K; Minematsu, T; Nagasaka, Y; Tabata, K | 1 |
| Armishaw, J; Cameron, PU; Chuah, J; Cooper, DA; Crowe, SM; Fairley, C; Gouillou, M; Hearps, A; Koelsch, KK; Leeansyah, E; Lewin, SR; Liu, JP; Pierce, AB; Smit, de V; Solomon, A; Spelman, T; Tennakoon, S; Velayudham, P | 1 |
| Baker, CJ; Capparelli, EV; Connor, JD; Englund, JA; McKinney, RE; Palumbo, P; Spector, SA | 1 |
| Collier, AC; Lockhart, DW; Marra, CM; Rees, TS; Schouten, JT | 1 |
| Stretcher, BN | 1 |
| Langtry, HD; Wilde, MI | 1 |
| Gollapudi, S; Gupta, S | 1 |
| Adler, WH; Nagel, JE | 1 |
| Calkins, DF; Lopez-Anaya, A; Smith, AL; Unadkat, JD | 1 |
| Erickson, JG; Hayes, KA; Lafrado, LJ; Marr, JM; Mathes, LE | 1 |
| Capparelli, E; Dankner, W; Mirochnick, M; Spector, SA; Sperling, RS; van Dyke, R | 1 |
| Claessen, FA; Hall, D; Hamann, D; Kauffmann, RH; Koopmans, PP; Kroon, ED; Kroon, FP; Lange, JM; Miedema, F; Montaner, JS; Otto, SA; Pakker, NG; Reiss, P; Roos, MT; Schellekens, PT; Sprenger, HG; ten Napel, CH; van der Ende, ME; Weigel, HM; Wit, FW | 1 |
| Bourdon, O; Demirdjian, S; Furlan, V; Magdalou, J; Taburet, AM | 1 |
| Busidan, Y; Dow-Edwards, DL | 1 |
| Deutsche, J; Goldsmith, JM; Green, D; Tang, M | 1 |
| Lopez-Anaya, A; Schumann, LA; Smith, AL; Unadkat, JD | 1 |
4 review(s) available for zidovudine and Aging
| Article | Year |
|---|---|
Pharmacokinetic optimisation of antiretroviral therapy in patients with HIV infection.
Topics: Aging; Antineoplastic Agents; Antiviral Agents; Didanosine; Drug Interactions; Guidelines as Topic; HIV Infections; Humans; Phosphorylation; Racial Groups; Sex Characteristics; Stavudine; Zalcitabine; Zidovudine | 1995 |
Zidovudine. An update of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Aging; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Intestinal Absorption; Metabolic Clearance Rate; Tissue Distribution; Zidovudine | 1993 |
P-glycoprotein (MDR 1 gene product) in cells of the immune system: its possible physiologic role and alteration in aging and human immunodeficiency virus-1 (HIV-1) infection.
Topics: Aging; Animals; Antigen-Presenting Cells; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carrier Proteins; Drug Resistance; Gene Expression; Genes; Hematopoietic Stem Cells; HIV Infections; HIV-1; Humans; Leukocytes; Lymphocyte Subsets; Macrophages; Membrane Glycoproteins; Mice; Models, Biological; Monocytes; Plasmodium falciparum; Protozoan Proteins; Rodentia; Zidovudine | 1993 |
Acquired immunodeficiency syndrome in the elderly.
Topics: Acquired Immunodeficiency Syndrome; Aged; Aging; Humans; Immunity, Cellular; Prognosis; Social Isolation; Transfusion Reaction; Zidovudine | 1994 |
4 trial(s) available for zidovudine and Aging
| Article | Year |
|---|---|
Population pharmacokinetics and pharmacodynamics of zidovudine in HIV-infected infants and children.
Topics: Adolescent; Aging; Area Under Curve; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Male; Metabolic Clearance Rate; Zidovudine | 2003 |
A prospective study of hearing changes after beginning zidovudine or didanosine in HIV-1 treatment-naïve people.
Topics: Adult; Aging; Anti-HIV Agents; Didanosine; Female; Hearing Loss; HIV Infections; Humans; Male; Middle Aged; Prospective Studies; Zidovudine | 2006 |
HIV-1 viral load and CD4 cell count in untreated children with vertically acquired asymptomatic or mild disease. Paediatric European Network for Treatment of AIDS (PENTA).
Topics: Aging; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Double-Blind Method; Drug Resistance, Microbial; Female; HIV Infections; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Male; Point Mutation; Quality Control; RNA, Viral; Viral Load; Viremia; Zidovudine | 1998 |
Zidovudine pharmacokinetics in premature infants exposed to human immunodeficiency virus.
Topics: Aging; Antiviral Agents; Female; Gestational Age; Half-Life; HIV Infections; Humans; Infant, Newborn; Infant, Premature; Male; Zidovudine | 1998 |
9 other study(ies) available for zidovudine and Aging
| Article | Year |
|---|---|
Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment.
Topics: Acetanilides; Adolescent; Adrenergic beta-3 Receptor Agonists; Adult; Aged; Aging; Butyrylcholinesterase; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Desipramine; Drug Interactions; Female; Gemfibrozil; Glucuronosyltransferase; Humans; Itraconazole; Lorazepam; Male; Middle Aged; Models, Biological; Renal Insufficiency; Thiazoles; Young Adult; Zidovudine | 2019 |
Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging.
Topics: Adenine; Adult; Aging; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; Cells, Cultured; Deoxycytidine; Dideoxynucleosides; Emtricitabine; Enzyme Activation; Female; HIV; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Regression Analysis; Reverse Transcriptase Inhibitors; Risk Factors; Telomerase; Telomere; Telomere Shortening; Tenofovir; Time Factors; Young Adult; Zidovudine | 2013 |
Effect of age on distribution of zidovudine (azidothymidine) into the cerebrospinal fluid of Macaca nemestrina.
Topics: Aging; Animals; Animals, Newborn; Female; Infusions, Intravenous; Injections, Intravenous; Macaca nemestrina; Pregnancy; Zidovudine | 1993 |
Prophylactic ZDV therapy prevents early viremia and lymphocyte decline but not primary infection in feline immunodeficiency virus-inoculated cats.
Topics: Age Factors; Aging; Animals; Antibodies, Viral; Antigens, Viral; Blotting, Southern; Cats; CD4-CD8 Ratio; Disease Models, Animal; Electrophoresis, Agar Gel; Feline Acquired Immunodeficiency Syndrome; Immunodeficiency Virus, Feline; Immunophenotyping; Infusions, Parenteral; Leukocyte Count; Lymphocytes; Polymerase Chain Reaction; Specific Pathogen-Free Organisms; Viremia; Zidovudine | 1993 |
Immune restoration does not invariably occur following long-term HIV-1 suppression during antiretroviral therapy. INCAS Study Group.
Topics: Adult; Aging; Anti-HIV Agents; Didanosine; Follow-Up Studies; HIV Infections; HIV-1; Humans; Immunologic Memory; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Time Factors; Zidovudine | 1999 |
Glucuronidation of drugs by hepatic microsomes derived from healthy and cirrhotic human livers.
Topics: Adolescent; Adult; Aging; Aryl Hydrocarbon Hydroxylases; Biotransformation; Child; Child, Preschool; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Glucuronates; Glucuronosyltransferase; Hepatitis; Humans; In Vitro Techniques; Lamotrigine; Liver Cirrhosis; Microsomes, Liver; Oxazepam; Oxidoreductases, N-Demethylating; Triazines; Umbelliferones; Xenobiotics; Zidovudine | 1999 |
Neurobehavioral effects of perinatal AZT exposure in Sprague-Dawley weaning rats.
Topics: Aging; Amphetamine; Animals; Animals, Newborn; Animals, Suckling; Anti-HIV Agents; Behavior, Animal; Body Weight; Central Nervous System Stimulants; Female; Grooming; Male; Motor Activity; Pregnancy; Rats; Rats, Sprague-Dawley; Sex Characteristics; Zidovudine | 1999 |
CD4 cells in HIV-1 infected hemophiliacs: effect of factor VIII concentrates.
Topics: Aging; Factor VIII; Follow-Up Studies; Hemophilia A; HIV Seropositivity; HIV-1; Humans; Leukocyte Count; T-Lymphocytes, Helper-Inducer; Transfusion Reaction; Zidovudine | 1991 |
Pharmacokinetics of zidovudine (azidothymidine). II. Development of metabolic and renal clearance pathways in the neonate.
Topics: Aging; Animals; Animals, Newborn; Female; Glucuronates; Glucuronosyltransferase; Humans; Macaca nemestrina; Male; Metabolic Clearance Rate; Zidovudine | 1990 |